Gene

KWMTBOMO09173

Pre Gene Modal

BGIBMGA003366

Annotation

PREDICTED:_integrator_complex_subunit_4_[Papilio_xuthus]

Location

Bomo_Chr15(-):12621955-12625885      View in EpiBrowser

Full name

Integrator complex subunit 4      

Location in the cell

Mitochondrial   Reliability : 1.173

CDS

ATGTCCGAACAGGACAATGCGTGCGTTTGGCAGCTGGCGCTGCGAGTGTGCGCCGCCCGCCTGTGCGCCGCCGTGCAGCAGAGCGCGGCTGGCAACACTAGCGGCGGGGTCGCTGCAGCTGGCAACACCGCCGCGCTGTCGGCCGTCGCAGCTCTCACGCACCACGCCGAAGTGTTGGACAGAATGCTGGCTTCCGCAGGTGTAGAGCCGGATCCGTTCACGATAGCAGTGTTCCGTCAGCTGTCGATGAACGCGGACAACAAGCCGGCCGCGCTGGCGAGGAGCATCCACCCGCTCCTACTGTCCGCGCCGCTGCCGGTCATACCCAAACCTAACCTTAAGATCGTGATGTGCAAAGCTAGCATAGTGGAGCCGGCCGCCGACAACGACTTGGTGGTGCGGTTCAGCGCGGGGCTCGTGGCCGGCGTGGCGCTGGAGGCCGAGGTGACGCGCGTGCGCTGTGCGGACGCGCTGCGCGTGCGCGTGGCCTACCCGGACCGCCGGGTGCACGCGCTGCTGCCGCCCCGGGACCACCTCCGGCCGCTCGACCATCACGACCAAAATGAGGATGGAACGCAAAACTTGCGTTTGCTGACTAAAGTTTTAATTTCACATGGAGTGTGGTCAGAACCATGTGGAGTGGACATTTCTATATGCCTAGCGGTCGAAGAAGGCGGTGGCAGAGAACCACCACAACTAGTAGAGCTTTGTAAACCAGTTAGAGTTACTGTAGCACCAAAGCCTATCAAACGAGGAATATAA

Protein

MSEQDNACVWQLALRVCAARLCAAVQQSAAGNTSGGVAAAGNTAALSAVAALTHHAEVLDRMLASAGVEPDPFTIAVFRQLSMNADNKPAALARSIHPLLLSAPLPVIPKPNLKIVMCKASIVEPAADNDLVVRFSAGLVAGVALEAEVTRVRCADALRVRVAYPDRRVHALLPPRDHLRPLDHHDQNEDGTQNLRLLTKVLISHGVWSEPCGVDISICLAVEEGGGREPPQLVELCKPVRVTVAPKPIKRGI

Description

Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424). Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424). Essential for development (PubMed:21078872). May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity).

Subunit

Belongs to the multiprotein complex Integrator, at least composed of IntS1, IntS2, IntS3, IntS4, omd/IntS5, IntS6, defl/IntS7, IntS8, IntS9, IntS10, IntS11, IntS12, asun/IntS13 and IntS14.

Similarity

Belongs to the Integrator subunit 4 family.

Keywords

Complete proteome   Nucleus   Reference proteome  

Feature

chain  Integrator complex subunit 4

Uniprot

H9J1H9   A0A2A4JG33   A0A2H1WH17   A0A3S2NAW5   A0A194PJB0   A0A194R938   + More
A0A1Y1KGH3   D6WNP8   E0VWN5   N6T0P4   A0A067R8X0   A0A0K8SS89   A0A146KUM2   A0A0A9XLV2   A0A2J7PTT1   A0A2J7PTS3   A0A2R7WQR2   A0A1B6KFJ8   T1HLK5   A0A1B6EUS6   A0A069DWU3   A0A023F1P2   A0A1B6JDN2   A0A2P8Z301   A0A0V0GA73   B7QNR7   A0A293LIB9   A0A1S3DQ96   A0A182SNE1   A0A1Q3F7B9   A0A182NQM0   A0A182QT24   A0A087UJI0   A0A084VXS1   A0A182X9J0   A0A182PRP9   A0A1B6E309   A0A182JG55   A0A182VHR8   A0A182VVV1   Q7PX93   A0A182L8R1   A0A182UJ60   A0A182HKH3   A0A182YBF8   A0A182RVR1   Q17LI2   A0A2L2YE14   A0A182K522   B0X7L2   A0A182GIB1   B4HA28   A0A147BQL0   V5HG76   W5J837   A0A2M4AHN6   A0A182FRM5   A0A023GJC6   A0A224YTP1   A0A182M153   A0A131Z4A6   A0A423THR1   L7M7B4   A0A131XES2   A0A1B0AXN7   A0A1E1XM30   W8BMN1   A0A2P6K3Q8   Q29FM0   A0A0P4WD44   A0A1I8Q286   T1PPE2   A0A336LYV8   B4L4X5   B4M1M8   A0A1E1XBR9   A0A1W4VV02   A0A1B0A5E6   A0A1A9V6R0   A0A2R5LJB7   B3N0B1   A0A0A1WXA9   B4JN25   A0A1S3DQZ2   A0A1A9X5K4   A0A240SWV1   A0A1I8MZZ2   B4NCA9   B4IJX9   A0A0P4W6N6   A0A034V2J9   A0A0K8U138   B4Q0A1   Q9W3E1   A0A1D2N3C4   A0A1I8Q290  

Pubmed

19121390    26354079    28004739    18362917    19820115    20566863    + More
23537049    24845553    26823975    25401762    26334808    25474469    29403074    24438588    12364791    14747013    17210077    20966253    25244985    17510324    26561354    26483478    17994087    29652888    25765539    20920257    23761445    28797301    26830274    25576852    28049606    29209593    24495485    15632085    28503490    25830018    25315136    25348373    17550304    10731132    12537572    21078872    23097424    27289101   

EMBL

BABH01023716    BABH01023717    NWSH01001620    PCG70668.1    ODYU01008620    SOQ52359.1    + More
RSAL01000300    RVE42754.1    KQ459602    KPI93511.1    KQ460615    KPJ13770.1    GEZM01088909    JAV57837.1    KQ971342    EFA03749.1    DS235823    EEB17791.1    APGK01049450    APGK01049451    APGK01049452    APGK01049453    APGK01049454    APGK01049455    KB741154    ENN73654.1    KK852619    KDR20101.1    GBRD01009800    JAG56024.1    GDHC01018438    GDHC01011408    JAQ00191.1    JAQ07221.1    GBHO01021907    GDHC01006813    JAG21697.1    JAQ11816.1    NEVH01021221    PNF19739.1    PNF19738.1    KK855304    PTY21912.1    GEBQ01029747    JAT10230.1    ACPB03014046    GECZ01028131    JAS41638.1    GBGD01000361    JAC88528.1    GBBI01003798    JAC14914.1    GECU01010376    JAS97330.1    PYGN01000219    PSN50884.1    GECL01001444    JAP04680.1    ABJB010057111    ABJB010192685    ABJB010283782    ABJB010306238    ABJB010382177    ABJB010414991    ABJB010632223    ABJB010708409    ABJB010738996    ABJB011062949    DS979863    EEC20489.1    GFWV01002869    MAA27599.1    GFDL01011593    JAV23452.1    AXCN02001514    KK120096    KFM77519.1    ATLV01018205    KE525224    KFB42765.1    GEDC01005019    JAS32279.1    AAAB01008987    EAA01205.5    APCN01000830    CH477215    EAT47554.1    IAAA01023360    LAA06374.1    DS232454    EDS42024.1    JXUM01065564    KQ562354    KXJ76091.1    CH479235    EDW36696.1    GEGO01002364    JAR93040.1    GANP01001823    JAB82645.1    ADMH02002105    ETN59025.1    GGFK01006969    MBW40290.1    GBBM01001366    JAC34052.1    GFPF01009149    MAA20295.1    AXCM01000928    GEDV01002962    JAP85595.1    QCYY01001702    ROT75993.1    GACK01005277    JAA59757.1    GEFH01003739    JAP64842.1    JXJN01005326    GFAA01003383    JAU00052.1    GAMC01006528    JAC00028.1    MWRG01032267    PRD20942.1    CH379066    EAL31380.1    GDRN01068023    JAI64262.1    KA649980    AFP64609.1    UFQT01000194    SSX21437.1    CH933810    EDW07603.1    CH940651    EDW65582.1    GFAC01002539    JAT96649.1    GGLE01005389    MBY09515.1    CH902640    EDV38315.1    GBXI01010805    JAD03487.1    CH916371    EDV92118.1    CCAG010000014    CCAG010000015    CH964239    EDW82468.1    CH480850    EDW51335.1    GDRN01068022    JAI64263.1    GAKP01022250    GAKP01022248    JAC36704.1    GDHF01032264    JAI20050.1    CM000162    EDX02238.1    AE014298    AY051460    LJIJ01000256    ODM99768.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000007266    + More
UP000009046    UP000019118    UP000027135    UP000235965    UP000015103    UP000245037    UP000001555    UP000079169    UP000075901    UP000075884    UP000075886    UP000054359    UP000030765    UP000076407    UP000075885    UP000075880    UP000075903    UP000075920    UP000007062    UP000075882    UP000075902    UP000075840    UP000076408    UP000075900    UP000008820    UP000075881    UP000002320    UP000069940    UP000249989    UP000008744    UP000000673    UP000069272    UP000075883    UP000283509    UP000092460    UP000001819    UP000095300    UP000009192    UP000008792    UP000192221    UP000092445    UP000078200    UP000007801    UP000001070    UP000091820    UP000092444    UP000095301    UP000007798    UP000001292    UP000002282    UP000000803    UP000094527   

PRIDE

H9J1H9    Q9W3E1   

Pfam

PF02985   HEAT        + More
PF01602   Adaptin_N

Interpro

IPR016024   ARM-type_fold        + More
IPR011989   ARM-like       
IPR000357   HEAT       
IPR002553   Clathrin/coatomer_adapt-like_N       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

H9J1H9   A0A2A4JG33   A0A2H1WH17   A0A3S2NAW5   A0A194PJB0   A0A194R938   + More
A0A1Y1KGH3   D6WNP8   E0VWN5   N6T0P4   A0A067R8X0   A0A0K8SS89   A0A146KUM2   A0A0A9XLV2   A0A2J7PTT1   A0A2J7PTS3   A0A2R7WQR2   A0A1B6KFJ8   T1HLK5   A0A1B6EUS6   A0A069DWU3   A0A023F1P2   A0A1B6JDN2   A0A2P8Z301   A0A0V0GA73   B7QNR7   A0A293LIB9   A0A1S3DQ96   A0A182SNE1   A0A1Q3F7B9   A0A182NQM0   A0A182QT24   A0A087UJI0   A0A084VXS1   A0A182X9J0   A0A182PRP9   A0A1B6E309   A0A182JG55   A0A182VHR8   A0A182VVV1   Q7PX93   A0A182L8R1   A0A182UJ60   A0A182HKH3   A0A182YBF8   A0A182RVR1   Q17LI2   A0A2L2YE14   A0A182K522   B0X7L2   A0A182GIB1   B4HA28   A0A147BQL0   V5HG76   W5J837   A0A2M4AHN6   A0A182FRM5   A0A023GJC6   A0A224YTP1   A0A182M153   A0A131Z4A6   A0A423THR1   L7M7B4   A0A131XES2   A0A1B0AXN7   A0A1E1XM30   W8BMN1   A0A2P6K3Q8   Q29FM0   A0A0P4WD44   A0A1I8Q286   T1PPE2   A0A336LYV8   B4L4X5   B4M1M8   A0A1E1XBR9   A0A1W4VV02   A0A1B0A5E6   A0A1A9V6R0   A0A2R5LJB7   B3N0B1   A0A0A1WXA9   B4JN25   A0A1S3DQZ2   A0A1A9X5K4   A0A240SWV1   A0A1I8MZZ2   B4NCA9   B4IJX9   A0A0P4W6N6   A0A034V2J9   A0A0K8U138   B4Q0A1   Q9W3E1   A0A1D2N3C4   A0A1I8Q290  

KEGG

101739991    K13141 integrator complex subunit 4 | (RefSeq) integrator complex subunit 4

GO

GO:0016180   GO:0032039   GO:0016192   GO:0030117   GO:0006886   GO:0016021   GO:0034472   GO:0005634  

Subcellular location

Nucleus  

Length:

253

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.86636

Exp number, first 60 AAs:

0.81901

Total prob of N-in:

0.13754

outside

1  -  253

 

 

Pi

130.683935

Theta

69.445176

Tajima's D

1.077504

CLR

0

CSRT

0.68111594420279

Interpretation

Uncertain