Gene

KWMTBOMO09153

Pre Gene Modal

BGIBMGA003375

Annotation

hypothetical_protein_KGM_00953_[Danaus_plexippus]

Location

Bomo_Chr15(-):12325456-12326757      View in EpiBrowser

Full name

Ribonuclease H1      

Location in the cell

Nuclear   Reliability : 2.297

CDS

ATGCCATTTTACGCAGTGGCAAAAGGTCGTACCTCAGGAATTTTTATGACTTGGGCAGATTGTGAAGCTCAGGTCAAAGGATTTTCTGGCGCTAAGTACAAAAAATTCGACACCATAAATCAGGCTCAGGACTATGTAGTCACCCAAGGAGGTAATAAGGGTCCGCCTTCTAAACCTGGAACTAGCTTTAAGGTCGGAAATAAAAAAACCGCGTCTAATAATCTGAAACGTCCCTATTCAACCACTACAAATGACAAGAATGAGAATGAAAACAAATTAAAATCACAAACTAAAGCTGAGGACGATTGCGATGAAGATTTTGAAATATCCGATGACCTGAACACTATTTTAACAAAGCAAATGGACGATATTGAAGCAAGATTAAAAGGTTTCCAGAAAGGAGTTGATAAAATAATAAAGAAAAATAGTGCTAAACCTGAACGAAAAACGATAATGATTGATCCACCCGAACCAAAAAAACAAAGACAAGACAACAACGATTTTGAAACTGACCCTGATGGCTTTGTACAGGTGTATACTGACGGAGCATGTTCAGCAAATGGTCGGAGTAGTGCGAAAGCAGGCTTGGGTGTGTACTGGGGAGATGGTCACTCTCTAAACGTTAGTGAACCGGTATCGGGCAGAGCAACTAATAATTGTGGTGAAATACAAGCGGCTACTAAGGCTATAAGACAAGCACTACAAAATGGAATTACAAAACTATCTATTAACACAGACTCTAAATTTTTAATCAATTCAGTCACTAAATGGATGCCTGGTTGGAAAAGGAAAGGTTGGAAATTGCAGTCTGGTGAACCAGTAAAAAACGAAAAAGATTTCAAAGATTTAGATAGTGTCCAGCACAAATTAGACATTAAGTGGAATTATGTAGAAGCACATCGTGGAATCCATGGTAACGAGATGGCAGATCAGTTGGCAAAGGCAGGAGCGGCTTCTTACAAATCATGA

Protein

MPFYAVAKGRTSGIFMTWADCEAQVKGFSGAKYKKFDTINQAQDYVVTQGGNKGPPSKPGTSFKVGNKKTASNNLKRPYSTTTNDKNENENKLKSQTKAEDDCDEDFEISDDLNTILTKQMDDIEARLKGFQKGVDKIIKKNSAKPERKTIMIDPPEPKKQRQDNNDFETDPDGFVQVYTDGACSANGRSSAKAGLGVYWGDGHSLNVSEPVSGRATNNCGEIQAATKAIRQALQNGITKLSINTDSKFLINSVTKWMPGWKRKGWKLQSGEPVKNEKDFKDLDSVQHKLDIKWNYVEAHRGIHGNEMADQLAKAGAASYKS

Description

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

Catalytic Activity

Endonucleolytic cleavage to 5'-phosphomonoester.

Cofactor

Mg(2+)

Similarity

Belongs to the RNase H family.

Uniprot

H9J1I8   A0A2A4ITF5   A0A2H1W5W1   A0A194RCW6   A0A194PL89   A0A3S2NJZ0   + More
A0A0L7L945   A0A182MH08   A0A1Q3G1H8   A0A182WQW2   A0A2M4BW48   A0A2M4BVW3   A0A182S4S7   A0A0M4E7N0   A0A3B0JS66   A0A1B0G5S5   A0A1A9US96   A0A0Q9WB12   A0A1J1I5K3   I5APZ9   A0A0Q9X961   I7M3J1   A0A034W138   A0A195B758   A0A2M4BX11   A0A1D2NEA3   F4WND3   D3TL25   A0A151XAS0   A0A3L8DMQ4   K7J9T7   E2A8N3   A0A158NG80   A0A026W1U7   A0A0A1WVN7   A0A0A9YCY3   A0A0V0GC64   A0A1A9ZAW8   A0A2R7W1K2   A0A146LWZ5   A0A023F7Z3   A0A224XG19   R4FM65   A0A3M7PMS8   A0A1B6CFC8   A0A3S1BXK2   A0A195FEA5  

EC Number

3.1.26.4

Pubmed

19121390    26354079    26227816    17994087    15632085    25348373    + More
27289101    21719571    20353571    30249741    20075255    20798317    21347285    24508170    25830018    25401762    26823975    25474469    30375419   

EMBL

BABH01023685    NWSH01008517    PCG62534.1    ODYU01006522    SOQ48448.1    KQ460615    + More
KPJ13751.1    KQ459602    KPI93499.1    RSAL01000063    RVE49500.1    JTDY01002197    KOB71895.1    AXCM01002726    GFDL01001409    JAV33636.1    GGFJ01008020    MBW57161.1    GGFJ01008022    MBW57163.1    CP012524    ALC42741.1    OUUW01000001    SPP75551.1    CCAG010015437    CH940662    KRF78468.1    CVRI01000040    CRK95018.1    CM000071    EIM53034.2    CH933808    KRG03945.1    EAL26050.4    GAKP01009686    JAC49266.1    KQ976574    KYM80353.1    GGFJ01008458    MBW57599.1    LJIJ01000069    ODN03562.1    GL888236    EGI64303.1    EZ422120    ADD18320.1    KQ982339    KYQ57390.1    QOIP01000006    RLU21661.1    AAZX01005976    GL437652    EFN70220.1    ADTU01015041    KK107487    EZA50037.1    GBXI01011158    JAD03134.1    GBHO01012662    JAG30942.1    GECL01001175    JAP04949.1    KK854205    PTY13061.1    GDHC01007452    JAQ11177.1    GBBI01001335    JAC17377.1    GFTR01004999    JAW11427.1    ACPB03021502    GAHY01001113    JAA76397.1    REGN01009768    RNA00413.1    GEDC01025195    JAS12103.1    RQTK01000013    RUS91353.1    KQ981625    KYN39010.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000037510    + More
UP000075883    UP000075920    UP000075900    UP000092553    UP000268350    UP000092444    UP000078200    UP000008792    UP000183832    UP000001819    UP000009192    UP000078540    UP000094527    UP000007755    UP000075809    UP000279307    UP000002358    UP000000311    UP000005205    UP000053097    UP000092445    UP000015103    UP000276133    UP000271974    UP000078541   

PRIDE

H9J1I8   

Pfam

PF00075   RNase_H        + More
PF01693   Cauli_VI

Interpro

IPR036397   RNaseH_sf        + More
IPR002156   RNaseH_domain       
IPR009027   Ribosomal_L9/RNase_H1_N       
IPR017067   RNase_H1_euk       
IPR011320   RNase_H1_N       
IPR012337   RNaseH-like_sf       
IPR037056   RNase_H1_N_sf       

SUPFAM

SSF53098   SSF53098        + More
SSF55658   SSF55658       

Gene 3D

3.30.420.10     3.40.970.10    

ProteinModelPortal

H9J1I8   A0A2A4ITF5   A0A2H1W5W1   A0A194RCW6   A0A194PL89   A0A3S2NJZ0   + More
A0A0L7L945   A0A182MH08   A0A1Q3G1H8   A0A182WQW2   A0A2M4BW48   A0A2M4BVW3   A0A182S4S7   A0A0M4E7N0   A0A3B0JS66   A0A1B0G5S5   A0A1A9US96   A0A0Q9WB12   A0A1J1I5K3   I5APZ9   A0A0Q9X961   I7M3J1   A0A034W138   A0A195B758   A0A2M4BX11   A0A1D2NEA3   F4WND3   D3TL25   A0A151XAS0   A0A3L8DMQ4   K7J9T7   E2A8N3   A0A158NG80   A0A026W1U7   A0A0A1WVN7   A0A0A9YCY3   A0A0V0GC64   A0A1A9ZAW8   A0A2R7W1K2   A0A146LWZ5   A0A023F7Z3   A0A224XG19   R4FM65   A0A3M7PMS8   A0A1B6CFC8   A0A3S1BXK2   A0A195FEA5  

PDB

2QKK     E-value=7.36501e-36,     Score=376

KEGG

101738648    K03469 ribonuclease HI [EC:3.1.26.4] | (RefSeq) ribonuclease H1

PATHWAY

03030    DNA replication - Bombyx mori (domestic silkworm)

GO

GO:0003676   GO:0004523   GO:0000287   GO:0015074   GO:0005739   GO:0016776   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

Length:

322

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00021

Exp number, first 60 AAs:

0.00021

Total prob of N-in:

0.02137

outside

1  -  322

 

 

Pi

123.729444

Theta

188.903204

Tajima's D

-1.572488

CLR

0.329333

CSRT

0.0530473476326184

Interpretation

Uncertain