Gene

KWMTBOMO09147

Pre Gene Modal

BGIBMGA007550

Annotation

PREDICTED:_ribonuclease_H2_subunit_B_[Papilio_xuthus]

Location

Bomo_Chr15(-):12158422-12161357      View in EpiBrowser

Full name

Ribonuclease H2 subunit B      

Alternative Name

Ribonuclease HI subunit B

Location in the cell

Nuclear   Reliability : 2.951

CDS

ATGACTAGATCACAAAATAAATTAAAAACAAAGGAACAGTTAAACACACCTATAGCTAAACGCGTGGAAAATACGTGGATTTTACTTGCAAAAGAGTCCTTATTGCAAAACAAGAATTTTCGATTTATCAATCTATCACATCCAGCGACTGGCAAAATAACAAAATATTGTTTGGAAGATGTCAGCAACAAAATATTTGAAGTCGTAACATATAACGAACCACATCGATCGTGGTTTATAGGAGAAACAGTAAAATCTGATCCTAGTATGCAAATTTTGACTCCGATAAATCCATTATTTTTAATACTTCCAAAAGTGAAGAGTCAATGCACTAGTAAAGCAGTACCTTTGGAGGATTTACTATCTGACAAGGGATATGATCAAATTGTGAATACTGTGAAAGATCTGGAAAAAATAGCTGACCGTAAGGGTCCAGTAGAGTTGAAAGCATACAAATATAATGAAGAAAAAACCTACAAATGGCTAGAGGACAGGATCCGGAATCTTGCTAAAGTACTGAAAGAAAAAAATCTGCATGTAACAGCTGGAGCCGTATCAGCGACATTTGTTTCTAGCAATTTAAACAATGTTGAAATTGAAGAAGAGTTCTACTTAAAATACGCACATGGACTGCTATCAGAATATCTTCAAGAAGAATTTGTACAAAATTTGGAGAAAAGGTTAAATTTTAGGCCAGAATTAATAGAGACCATAGGAATGAAACGTAAATCTGAAATAAATGATTTACATGAAAACACGAAAAAAATAAAATTAGAAAACTCTTCTCTAGAAGAAGTGGTTAGTGAAAGTATGTCCACTCAAAGTTTTACAGAAAACAAAAAGAACAAGACATTGTCTGCAAAAGAAAAAGCAAGACAGAAGGCAGCTAGTGGAATGAAAACAATTTCATCCTTTTTTACAAAAAAATAA

Protein

MTRSQNKLKTKEQLNTPIAKRVENTWILLAKESLLQNKNFRFINLSHPATGKITKYCLEDVSNKIFEVVTYNEPHRSWFIGETVKSDPSMQILTPINPLFLILPKVKSQCTSKAVPLEDLLSDKGYDQIVNTVKDLEKIADRKGPVELKAYKYNEEKTYKWLEDRIRNLAKVLKEKNLHVTAGAVSATFVSSNLNNVEIEEEFYLKYAHGLLSEYLQEEFVQNLEKRLNFRPELIETIGMKRKSEINDLHENTKKIKLENSSLEEVVSESMSTQSFTENKKNKTLSAKEKARQKAASGMKTISSFFTKK

Description

Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).

Subunit

The RNase H2 complex is a heterotrimer composed of the catalytic subunit rnaseh2a and the non-catalytic subunits rnaseh2b and rnaseh2c.
The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

Similarity

Belongs to the RNase H2 subunit B family.

Keywords

Complete proteome   Nucleus   Reference proteome  

Feature

chain  Ribonuclease H2 subunit B

Uniprot

H9JDF3   A0A1E1VY17   A0A2A4JCG1   A0A194R7X0   A0A0L7L9V6   I4DPS9   + More
S4PCA0   A0A437B8Y3   A0A212F0B6   A0A194PL84   A0A1Y1KXD9   N6THU3   A0A310SNB7   A0A2A3EAN2   A0A087ZRD0   A0A2J7QLE9   F4WH28   D6WMH9   A0A195BT07   A0A158NT91   A0A0L7R3W6   A0A151JW26   E2BEF7   A0A195E360   A0A232EJ65   A0A154PE26   K7JDG3   A0A195CAN2   A0A0M9A3I0   E2A5A7   E9INW9   A0A151WZX8   A0A1B6DRY5   A0A1B6HFF3   A0A026WZZ1   A0A1B6FMH0   A0A3L8D3H4   A0A1B6LCP7   A0A067RNJ2   A0A2P8YV45   A0A1B6LL34   A0A1B6LF92   A0A1B0CPT4   W5L4U7   A0A3B1ITC9   B0WCS6   A0A3N0XKR7   A0A3B4EIP3   E3TEX9   A0A2R8QEF7   A0A1Q3EWZ3   Q28GD9   A0A0N7ZBA0   A0A401T3Z5   A0A0P5EA35   A0A0P5CCI0   G8JLU1   F1QN47   A0A2D4MVM1   R4G8Z4   A0A2R8QE52   A0A0P5BMU0   A0A0N8CWL1   A0A3B4D231   A0A0P5R8D0   A0A0P4YH62   A0A0P5A221   A0A0P5RM44   A0A0P5MV09   A0A0P6FK13   A0A0P5N5Z6   V9L8M3   A0A1J1IWK1   A0A0P6CJ15   A0A3Q1HSQ4   A0A0N8CRI1   A0A2D4KQ88   A0A3Q3Q7J7   A0A0P5M710   A0A2D4FEZ4   A0A2D4P7W8   A0A3P9I3B6   A0A3P9KRN6   A0A336LCZ1   A0A1L8HIV1   Q5HZP1   A0A401Q4Y5   A0A3Q3G161   A0A3B3DI26   A0A1U7RYV4   A0A3B5B4P1   A0A151NC22   A0A452HXX9   A0A3P8UZ38   A0A1L8HIQ8  

Pubmed

19121390    26354079    26227816    22651552    23622113    22118469    + More
28004739    23537049    21719571    18362917    19820115    21347285    20798317    28648823    20075255    21282665    24508170    30249741    24845553    29403074    25329095    20634964    23594743    30297745    20431018    24402279    17554307    27762356    29451363    22293439    28562605    24487278   

EMBL

BABH01030051    GDQN01011483    JAT79571.1    NWSH01001887    PCG69787.1    KQ460615    + More
KPJ13747.1    JTDY01002028    KOB72288.1    AK403765    BAM19919.1    GAIX01005547    JAA87013.1    RSAL01000115    RVE46904.1    AGBW02011130    OWR47172.1    KQ459602    KPI93494.1    GEZM01071093    JAV66083.1    APGK01037617    KB740948    KB632364    ENN77383.1    ERL93614.1    KQ762520    OAD55764.1    KZ288322    PBC28121.1    NEVH01013247    PNF29414.1    GL888148    EGI66507.1    KQ971343    EFA04271.1    KQ976409    KYM90932.1    ADTU01025732    KQ414663    KOC65441.1    KQ981686    KYN37946.1    GL447768    EFN86002.1    KQ979701    KYN19583.1    NNAY01004075    OXU18409.1    KQ434885    KZC10067.1    AAZX01014366    KQ978072    KYM97256.1    KQ435747    KOX76495.1    GL436894    EFN71388.1    GL764397    EFZ17686.1    KQ982636    KYQ53317.1    GEDC01008851    JAS28447.1    GECU01034298    JAS73408.1    KK107061    EZA61321.1    GECZ01018389    JAS51380.1    QOIP01000014    RLU14754.1    GEBQ01018512    JAT21465.1    KK852521    KDR22140.1    PYGN01000342    PSN48116.1    GEBQ01015604    JAT24373.1    GEBQ01017657    JAT22320.1    AJWK01022620    DS231890    EDS43802.1    RJVU01070621    ROI57079.1    GU588912    ADO28865.1    BX530033    GFDL01015235    JAV19810.1    CR761427    BC121543    GDRN01087192    JAI61064.1    BEZZ01000981    GCC37334.1    GDIP01144400    JAJ79002.1    GDIP01172498    JAJ50904.1    AAMC01061537    BX649442    CU855930    IACM01130007    LAB37148.1    GAHY01000117    JAA77393.1    CU151883    GDIP01187451    JAJ35951.1    GDIP01091759    JAM11956.1    GDIQ01109196    JAL42530.1    GDIP01237052    JAI86349.1    GDIP01206644    JAJ16758.1    GDIQ01117749    JAL33977.1    GDIQ01153140    JAK98585.1    GDIP01100208    GDIQ01063225    JAM03507.1    JAN31512.1    GDIQ01150642    JAL01084.1    JW875306    AFP07823.1    CVRI01000061    CRL04066.1    GDIP01014180    JAM89535.1    GDIP01105999    JAL97715.1    IACL01077559    LAB10828.1    GDIQ01159790    JAK91935.1    IACJ01062574    LAA46032.1    IACN01054212    LAB54091.1    UFQS01002706    UFQT01002706    SSX14573.1    SSX33971.1    CM004468    OCT95971.1    BC088940    BFAA01009653    GCB80443.1    AKHW03003532    KYO34368.1    OCT95972.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000037510    UP000283053    UP000007151    + More
UP000053268    UP000019118    UP000030742    UP000242457    UP000005203    UP000235965    UP000007755    UP000007266    UP000078540    UP000005205    UP000053825    UP000078541    UP000008237    UP000078492    UP000215335    UP000076502    UP000002358    UP000078542    UP000053105    UP000000311    UP000075809    UP000053097    UP000279307    UP000027135    UP000245037    UP000092461    UP000018467    UP000002320    UP000261440    UP000221080    UP000000437    UP000008143    UP000287033    UP000183832    UP000265040    UP000261600    UP000265200    UP000265180    UP000186698    UP000288216    UP000261660    UP000261560    UP000189705    UP000261400    UP000050525    UP000291020    UP000265120   

PRIDE

H9JDF3    Q28GD9    F1QN47    Q5HZP1   

Pfam

PF17745   Ydr279_N        + More
PF09468   RNase_H2-Ydr279
PF04146   YTH
PF14712   Snapin_Pallidin
PF05175   MTS

Interpro

IPR019024   RNase_H2_suB_wHTH        + More
IPR040456   RNase_H2_suB       
IPR041195   Rnh202_N       
IPR007275   YTH_domain       
IPR002052   DNA_methylase_N6_adenine_CS       
IPR029063   SAM-dependent_MTases       
IPR007848   Small_mtfrase_dom       
IPR004557   PrmC-related       
IPR028119   Snapin/Pallidin/Snn1       

SUPFAM

SSF53335   SSF53335       

CDD

cd09270  RNase_H2-B

ProteinModelPortal

H9JDF3   A0A1E1VY17   A0A2A4JCG1   A0A194R7X0   A0A0L7L9V6   I4DPS9   + More
S4PCA0   A0A437B8Y3   A0A212F0B6   A0A194PL84   A0A1Y1KXD9   N6THU3   A0A310SNB7   A0A2A3EAN2   A0A087ZRD0   A0A2J7QLE9   F4WH28   D6WMH9   A0A195BT07   A0A158NT91   A0A0L7R3W6   A0A151JW26   E2BEF7   A0A195E360   A0A232EJ65   A0A154PE26   K7JDG3   A0A195CAN2   A0A0M9A3I0   E2A5A7   E9INW9   A0A151WZX8   A0A1B6DRY5   A0A1B6HFF3   A0A026WZZ1   A0A1B6FMH0   A0A3L8D3H4   A0A1B6LCP7   A0A067RNJ2   A0A2P8YV45   A0A1B6LL34   A0A1B6LF92   A0A1B0CPT4   W5L4U7   A0A3B1ITC9   B0WCS6   A0A3N0XKR7   A0A3B4EIP3   E3TEX9   A0A2R8QEF7   A0A1Q3EWZ3   Q28GD9   A0A0N7ZBA0   A0A401T3Z5   A0A0P5EA35   A0A0P5CCI0   G8JLU1   F1QN47   A0A2D4MVM1   R4G8Z4   A0A2R8QE52   A0A0P5BMU0   A0A0N8CWL1   A0A3B4D231   A0A0P5R8D0   A0A0P4YH62   A0A0P5A221   A0A0P5RM44   A0A0P5MV09   A0A0P6FK13   A0A0P5N5Z6   V9L8M3   A0A1J1IWK1   A0A0P6CJ15   A0A3Q1HSQ4   A0A0N8CRI1   A0A2D4KQ88   A0A3Q3Q7J7   A0A0P5M710   A0A2D4FEZ4   A0A2D4P7W8   A0A3P9I3B6   A0A3P9KRN6   A0A336LCZ1   A0A1L8HIV1   Q5HZP1   A0A401Q4Y5   A0A3Q3G161   A0A3B3DI26   A0A1U7RYV4   A0A3B5B4P1   A0A151NC22   A0A452HXX9   A0A3P8UZ38   A0A1L8HIQ8  

PDB

3P5J     E-value=8.00424e-22,     Score=255

KEGG

101736756    K10744 ribonuclease H2 subunit B | (RefSeq) ribonuclease H2 subunit B

PATHWAY

03030    DNA replication - Bombyx mori (domestic silkworm)

GO

GO:0032299   GO:0003723   GO:0005654   GO:0005634   GO:0006401   GO:0004523   GO:0009259   GO:0008168   GO:0003676   GO:0016021   GO:0006508   GO:0015074   GO:0005739   GO:0016776   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

PANTHER

PTHR13383  

Subcellular location

Nucleus  

Length:

309

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01289

Exp number, first 60 AAs:

9e-05

Total prob of N-in:

0.20205

outside

1  -  309

 

 

Pi

238.294255

Theta

179.388403

Tajima's D

0.86693

CLR

0.003429

CSRT

0.629118544072796

Interpretation

Uncertain