Gene

KWMTBOMO09135  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007543

Annotation

PREDICTED:_peptidyl-prolyl_cis-trans_isomerase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(+):11917641-11919370      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase       + More
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4      

Alternative Name

Parvulin-14
Peptidyl-prolyl cis-trans isomerase Pin4
Rotamase Pin4

Location in the cell

Cytoplasmic   Reliability : 1.354 Nuclear   Reliability : 1.96

CDS

ATGCCACCAAAAAAACAACCCGAAAAAGTTGCCAAAGGTGGCGGGAGCGCTAAAGGAAGTGGTGGTAAAACGAGTGGCGATACAAAAGAATCTGCAGCAAAGGAGAAAAAAGGTGGGACAGCTGTCAAAGTACGTCACATACTATGTGAAAAGCAATCCAAATGTTTAGAAGCGTTAGAGAAATTAAAAGCCGGGCAAAAGTTTCCTGATGTAGCAGCAGCTTATAGTGAAGACAAGGCAAGGCAAGGTGGAGATCTAGGCTGGATGACCAGAGGTTCAATGGTTGGTCCATTTCAAGATGCTGCATTTGCTTTGCCAATATCATCTGTAACTAATCCAGTTTACACAAACCCGCCAGTTAAAACGAAATTTGGTTATCATATAATTATGGTCGAAGGGAAGAAATGA

Protein

MPPKKQPEKVAKGGGSAKGSGGKTSGDTKESAAKEKKGGTAVKVRHILCEKQSKCLEALEKLKAGQKFPDVAAAYSEDKARQGGDLGWMTRGSMVGPFQDAAFALPISSVTNPVYTNPPVKTKFGYHIIMVEGKK

Description

May be involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to DNA (By similarity).

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

Keywords

Complete proteome   Cytoplasm   Cytoskeleton   DNA-binding   Isomerase   Nucleus   Reference proteome   Rotamase  

Feature

chain  Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

Uniprot

Q2F670   A0A194RCV1   I4DMX1   H9JDE6   A0A194PJ83   A0A212EP31   + More
A0A2H1VTN1   A0A2A4JEJ2   A0A0L7LL41   S4PYG4   A0A2Z5U7D0   D6WQF8   A0A1Y1KTV2   N6TDK7   U5EZI7   A0A2J7PRS0   I4DPS8   A0A1J1J3C2   A0A0K8UHX2   A0A034VKG2   A0A067QQQ3   W8BYZ0   A0A0J7K5U5   B4IJJ6   A0A1W4VLX7   Q9VBU4   B4QUR9   Q296L8   B4GEZ6   B4PUA0   B3LWJ7   B3P6N4   A0A023GHV2   G3MLG2   A0A1Z5L6R2   A0A293M222   E2ATA5   A0A444SSN6   A0A090XA76   A0A1B0DBR4   A0A0K8RJQ1   A0A0K8RAN3   B4NIU9   A0A1E1WYW4   A0A1A9Z3P9   A0A3B0KDK6   A0A195F1B6   A0A1S3DFD8   A0A195E7G1   A0A026WIL3   A0A131XE87   F4X6L2   B7PP75   A0A224YXG7   A0A131YHC8   L7M638   E2BE26   A0A0C9RSD0   A0A195B2J9   A0A158NLD5   A0A2S2QJG0   A0A1W4WHP0   A0A131Y3W2   A0A1A9Y3Z0   A0A0L7R4J4   A0A2L2YA33   A0A2P6L0K6   T1EUP4   A0A3N0YMB1   A0A1L8DU66   A0A0B2VJF7   A7SIW4   A0A0R3PJB6   A0A1I7XY27   A0A2P8YH95   A0A444UU06   W2TI59   B2GQB4   Q503Y7   A0A0N0BHD0   A0A3B4WJF1   C3KID0   A0A3B4U475   A0A1L8DUK2   A0A0B1SVC4   A0A132AIS2   E9IZ66   A0A3Q0SA74   A0A0N5BVB9   A0A3B4EJX5   A0A2P2I4Y0   A0A226D031   A0A0P5R773   A0A3Q1H5R9   A0A0B1TKJ7   A0A0C2FIV3   A0A0K0DI39   I3KMG1   A0A0A9VSP6  

EC Number

5.2.1.8

Pubmed

26354079    22651552    19121390    22118469    26227816    23622113    + More
18362917    19820115    28004739    23537049    25348373    24845553    24495485    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    17550304    22216098    28528879    20798317    25970599    28503490    24508170    30249741    28049606    21719571    28797301    26830274    25576852    26131772    21347285    26561354    23254933    17615350    26392177    29403074    26555130    21282665    25186727    25401762    26823975   

EMBL

DQ311202    ABD36147.1    KQ460615    KPJ13736.1    AK402639    BAM19261.1    + More
BABH01030069    KQ459602    KPI93486.1    AGBW02013545    OWR43226.1    ODYU01004370    SOQ44180.1    NWSH01001662    PCG70495.1    JTDY01000728    KOB76084.1    GAIX01003333    JAA89227.1    AP017517    BBB06859.1    KQ971354    EFA06964.1    GEZM01080207    JAV62297.1    APGK01034123    KB740904    KB632006    ENN78449.1    ERL87961.1    GANO01000724    JAB59147.1    NEVH01021953    PNF19021.1    AK403763    BAM19918.1    CVRI01000067    CRL06933.1    GDHF01026364    JAI25950.1    GAKP01016350    JAC42602.1    KK853131    KDR10898.1    GAMC01002023    JAC04533.1    LBMM01013490    KMQ85614.1    CH480848    EDW51187.1    AE014297    AY071761    AAF56433.1    AAL49383.1    CM000364    EDX14385.1    CM000070    EAL28439.1    CH479182    EDW34181.1    CM000160    EDW98787.1    CH902617    EDV41591.1    CH954182    EDV53704.1    GBBM01003038    JAC32380.1    JO842713    AEO34330.1    GFJQ02004010    JAW02960.1    GFWV01008411    MAA33140.1    GL442545    EFN63350.1    SAUD01024521    RXG56414.1    GBIH01001761    JAC92949.1    AJVK01030216    GADI01003044    JAA70764.1    GADI01005591    JAA68217.1    CH964272    EDW84851.1    GFAC01007020    JAT92168.1    OUUW01000008    SPP84329.1    KQ981864    KYN34365.1    KQ979568    KYN20774.1    KK107185    QOIP01000012    EZA55813.1    RLU16094.1    GEFH01004650    JAP63931.1    GL888818    EGI57794.1    ABJB011088889    DS756244    EEC08397.1    GFPF01010459    MAA21605.1    GEDV01011236    JAP77321.1    GACK01006431    JAA58603.1    GL447755    EFN86013.1    GBZX01002554    JAG90186.1    KQ976662    KYM78429.1    ADTU01019320    GGMS01008109    MBY77312.1    GEFM01002598    JAP73198.1    KQ414657    KOC65802.1    IAAA01012680    IAAA01012681    LAA05016.1    MWRG01002900    PRD32111.1    AMQM01001503    KB097571    ESN94181.1    RJVU01035834    ROL47304.1    GFDF01004138    JAV09946.1    JPKZ01001505    KHN81534.1    DS469672    EDO36374.1    UYYA01003819    VDM56120.1    PYGN01000600    PSN43554.1    SCEB01008111    RXM91646.1    KI658624    ETN81765.1    BC164671    AAI64671.1    BC095126    KQ435757    KOX75841.1    BT082695    ACQ58402.1    GFDF01004139    JAV09945.1    KN554501    KHJ89243.1    JXLN01015967    KPM10886.1    GL767119    EFZ14112.1    IACF01003327    LAB68946.1    LNIX01000054    OXA37646.1    GDIP01144613    GDIQ01104714    LRGB01001856    JAJ78789.1    JAL47012.1    KZS10301.1    KN549691    KHJ96352.1    KN768713    KIH46674.1    AERX01014037    AERX01014038    GBHO01044855    GDHC01020674    JAF98748.1    JAP97954.1   

Proteomes

UP000053240    UP000005204    UP000053268    UP000007151    UP000218220    UP000037510    + More
UP000007266    UP000019118    UP000030742    UP000235965    UP000183832    UP000027135    UP000036403    UP000001292    UP000192221    UP000000803    UP000000304    UP000001819    UP000008744    UP000002282    UP000007801    UP000008711    UP000000311    UP000288706    UP000092462    UP000007798    UP000092445    UP000268350    UP000078541    UP000079169    UP000078492    UP000053097    UP000279307    UP000007755    UP000001555    UP000008237    UP000078540    UP000005205    UP000192223    UP000092443    UP000053825    UP000015101    UP000031036    UP000001593    UP000050601    UP000267027    UP000095287    UP000245037    UP000000437    UP000053105    UP000261360    UP000261420    UP000261340    UP000046392    UP000261440    UP000198287    UP000076858    UP000265040    UP000035642    UP000005207   

PRIDE

Q2F670    H9JDE6    Q9VBU4    G3MLG2    B7PP75    L7M638    + More

Interpro

IPR000297   PPIase_PpiC       

ProteinModelPortal

Q2F670   A0A194RCV1   I4DMX1   H9JDE6   A0A194PJ83   A0A212EP31   + More
A0A2H1VTN1   A0A2A4JEJ2   A0A0L7LL41   S4PYG4   A0A2Z5U7D0   D6WQF8   A0A1Y1KTV2   N6TDK7   U5EZI7   A0A2J7PRS0   I4DPS8   A0A1J1J3C2   A0A0K8UHX2   A0A034VKG2   A0A067QQQ3   W8BYZ0   A0A0J7K5U5   B4IJJ6   A0A1W4VLX7   Q9VBU4   B4QUR9   Q296L8   B4GEZ6   B4PUA0   B3LWJ7   B3P6N4   A0A023GHV2   G3MLG2   A0A1Z5L6R2   A0A293M222   E2ATA5   A0A444SSN6   A0A090XA76   A0A1B0DBR4   A0A0K8RJQ1   A0A0K8RAN3   B4NIU9   A0A1E1WYW4   A0A1A9Z3P9   A0A3B0KDK6   A0A195F1B6   A0A1S3DFD8   A0A195E7G1   A0A026WIL3   A0A131XE87   F4X6L2   B7PP75   A0A224YXG7   A0A131YHC8   L7M638   E2BE26   A0A0C9RSD0   A0A195B2J9   A0A158NLD5   A0A2S2QJG0   A0A1W4WHP0   A0A131Y3W2   A0A1A9Y3Z0   A0A0L7R4J4   A0A2L2YA33   A0A2P6L0K6   T1EUP4   A0A3N0YMB1   A0A1L8DU66   A0A0B2VJF7   A7SIW4   A0A0R3PJB6   A0A1I7XY27   A0A2P8YH95   A0A444UU06   W2TI59   B2GQB4   Q503Y7   A0A0N0BHD0   A0A3B4WJF1   C3KID0   A0A3B4U475   A0A1L8DUK2   A0A0B1SVC4   A0A132AIS2   E9IZ66   A0A3Q0SA74   A0A0N5BVB9   A0A3B4EJX5   A0A2P2I4Y0   A0A226D031   A0A0P5R773   A0A3Q1H5R9   A0A0B1TKJ7   A0A0C2FIV3   A0A0K0DI39   I3KMG1   A0A0A9VSP6  

PDB

1FJD     E-value=6.51538e-39,     Score=397

KEGG

692830    K09579 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8] | (RefSeq) peptidyl-proly

GO

GO:0003755   GO:0005730   GO:0005737   GO:0005819   GO:0003677   GO:0016853   GO:0016592   GO:0006260   GO:0019205   GO:0005739   GO:0016776   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

Subcellular location

Nucleus  
Nucleolus  
Cytoplasm  
Cytoskeleton  
Spindle  

Length:

135

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04401

Exp number, first 60 AAs:

0

Total prob of N-in:

0.22394

outside

1  -  135

 

 

Pi

146.359726

Theta

159.503314

Tajima's D

1.020101

CLR

0.504372

CSRT

0.667916604169791

Interpretation

Uncertain