Gene

KWMTBOMO09126

Pre Gene Modal

BGIBMGA007539

Annotation

PREDICTED:_E3_ubiquitin-protein_ligase_TRIP12_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr15(+):11760101-11764655      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 2.34

CDS

ATGAAGCGGAGTTCTGAACACAAACTCGAGTTCCTGATCGGCGATACAGTGCTGCCGTACAACATGACCGTGTACCAGGCGGTGCGACAGTTCGGGGAACAAACGGACGCCGACACGGACACCGAAACTCCATTGGCGAACGCGGGGATATGGGTCCAGACACACACGATATATTATCGCGCCGTGGAGCCAAATGAACAACCGCGTTCCGAAAGCACTCCGTCAAAGAAAGGCAAAGGACAACCCACAAAGATCTCATCCCGACGAAAACCTGATTTACTCTGGAACGAGGGCGCGGTGCCGGCGCGTGCGTCATCGCTGGTGGTGATGGTGCGCGCGGCGCTGCTCACGGAGGGCGACGTGCGGGACGCCTCGCTGCCCGCGCTGGGCGTGCTGCGCGCCCTGCACGCCCTGTCGCGCCACTGGCACGCGCTCTACCGCGCCGCCTGTCTGCCGGACCACCGCCCTCTCGTGCCGCACGCAGACTTCATCAATGCTAAGCTCGCCGCCAAAGCCAATAGACAGTTGCAAGATCCATTAGTAATAATGACAGGCAATCTACCGCCGTGGCTAAAAAAGATCGCCTACGCATGTCCGTTCGTGTTGCCGTTCGAGTGTCGGCACTTGTTATTCTACGTGGTGTCTTTCGACCGCGACCGCGCCCTGCAGCGGCTGCTGGAGGCGGGCGGGGAGCGCGGCGGGACGGCGGGCGGCGAGACGGAGCGCGTGGCGCCTCGCCTCGACCGACGCAAGCGCACCGTGCAGCGACACAACGTGCTACGCCAGGCCGAACACGTCATGCACGAGTTCGCGCACACCAAGGCGCTCCTCGAGATTCAGTACGAGAACGAAGTCGGCACCGGTCTCGGGCCCACCTTGGAGTTCTACGCGCTGGTCTCGCAAGAACTGCAACGCGCGGATCTCGATCTTTGGCACGGCAGCGAAAACTTCAAACAGAAGCCTAGCTCTTTCGGGGGTGAAATTGTGAAATCGGGCGAAGCGGCGGCCCGCCTCGCTACTTCGGTACGCGACGGTTTGAACTTGGACGAAGAACGTACGCGCGCCACTTCACCGACGGACCGTGATAAAGATGCTCCCGAGCCGGCTGCCTTCGTTTCGTGGCCGTGCGGACTCTTTCCGCAGGCGCTAGGTCGCAACGCCCGCGCATCTCATCTCTCTCGAGTCAAAGCCAAATTCCGCTTCCTTGGAAAGTTCATGGCTAAAGCGGTTATGGATTCACGAATGGTGGATATTCCTCTGTCGGTAACAATGTACCGATGGGTGGTGAACGAAGAACGTTGGCTAAGCTTGAGCGACGTGCGACACGTGGCGCCCGAACTGTGGCGTTCTCTGTGTCGTTTACGGCGCGTCGCCGATCGCGCACAACACATCGCAGCCGACACCCGACATACACAGGACCAGAAGAATCAACTTATAAGTAACCTTGAGCTAGATGGATGTCCGATTGAAGAGCTCGGGCTCGACTTCATATTGCCCGGAGACGGATGCACGGAACTGCGTCGGGGTGGCAGAGACATGCCCGTCACTGCGCACAATTTGCAAAATTATATTAATCTCGTAACTCATTGGCTACTTTTTGAAGGTGTATCAAAACAGATGGAAGCTTTCAAAGAAGGATTTGAGTCGGTATTTCCTTTGAGTAACTTAAAAATATTTTATCCTGAAGAGTTGGAACAAGTGTTTTGCGGAAGTCCTTCAGGTGGTCGTGACCAACGATGGGATCCACGTATGCTGGCGGAATGTATTCGTCCGGATCATGGATACAATGCAGAATCGCGGGCTATACGCATGCTTATTGATATTTTGGCTTCGTACAACCGTGAAGAACAACGACACTTCTTACAGTTTGTTACTGGAAGTCCAAGGCTGCCAACTGGTGGATTCAAGGCATTGAATCCACCACTAACTGTGGTGCGTAAATCGCTGGAGTCTTCATTGGATCCGGATGAATATTTGCCATCAGTGATGACATGTGTCAACTACTTGAAGCTGCCAGACTACAGTAGCGCTGAGGTGATGCGCGCTAAGCTACGGCTCGCTGCTTCTGAGGGACAACATTCGTTCCACCTTTCATAA

Protein

MKRSSEHKLEFLIGDTVLPYNMTVYQAVRQFGEQTDADTDTETPLANAGIWVQTHTIYYRAVEPNEQPRSESTPSKKGKGQPTKISSRRKPDLLWNEGAVPARASSLVVMVRAALLTEGDVRDASLPALGVLRALHALSRHWHALYRAACLPDHRPLVPHADFINAKLAAKANRQLQDPLVIMTGNLPPWLKKIAYACPFVLPFECRHLLFYVVSFDRDRALQRLLEAGGERGGTAGGETERVAPRLDRRKRTVQRHNVLRQAEHVMHEFAHTKALLEIQYENEVGTGLGPTLEFYALVSQELQRADLDLWHGSENFKQKPSSFGGEIVKSGEAAARLATSVRDGLNLDEERTRATSPTDRDKDAPEPAAFVSWPCGLFPQALGRNARASHLSRVKAKFRFLGKFMAKAVMDSRMVDIPLSVTMYRWVVNEERWLSLSDVRHVAPELWRSLCRLRRVADRAQHIAADTRHTQDQKNQLISNLELDGCPIEELGLDFILPGDGCTELRRGGRDMPVTAHNLQNYINLVTHWLLFEGVSKQMEAFKEGFESVFPLSNLKIFYPEELEQVFCGSPSGGRDQRWDPRMLAECIRPDHGYNAESRAIRMLIDILASYNREEQRHFLQFVTGSPRLPTGGFKALNPPLTVVRKSLESSLDPDEYLPSVMTCVNYLKLPDYSSAEVMRAKLRLAASEGQHSFHLS

Catalytic Activity

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Uniprot

H9JDE2   A0A437B0L8   A0A212FCE6   A0A194PL69   A0A194R8Z6   A0A2H1V9S7   + More
A0A2J7R148   A0A2J7R149   A0A067RUC7   A0A2J7R154   A0A1B6CDK3   A0A1B6HPM5   A0A1B6HIP0   A0A1B6EU11   A0A1B6I391   A0A1B6HFS4   A0A1B0DRJ3   A0A1B6ME64   A0A1W4XCN5   A0A1L8DSR1   A0A1J1IHY8   A0A023F2M2   A0A224X9E7   A0A069DYG2   A0A0K8TBZ6   A0A0K8TBT8   A0A0L7QMD7   T1HY39   A0A1Y1N832   A0A0A9XEA8   A0A146KYS7   A0A0K8TBV2   A0A0A9XLJ3   A0A146LSW2   A0A0A9YA47   A0A146L998   A0A0A9XGQ4   A0A146MHM7   A0A0A9X6F5   A0A0A9XDB1   A0A139WIF7   A0A0N7Z8S6   D6WKR6   E9IME8   A0A3L8D484   A0A151WFQ6   A0A158NCA7   A0A026W567   A0A151J6G5   A0A195CEA5   A0A195BW90   A0A131Z0H8   A0A131Z199   T1IVF8   A0A087TI59   A0A087ZT69   A0A0P5YJT4   U4U6X9   A0A1S3K667   A0A0P5LJN1   A0A0P5NSZ6   A0A0N7ZEX9   A0A0P5RS56   A0A0N8CDX9   A0A0P6ADL8   A0A0P5R4P5   A0A1S3K657   A0A1S3K6I9   A0A1S3K662   A0A1S3K781   A0A3G2KX41   A0A162CJF2   A0A0P6G2K6   A0A0N8ABG6   A0A0P5U745   A0A0P5SUR5   A0A0P5KJU8   A0A0N8AZX9   A0A2A3ED50   A0A195F9P5   A0A0P5DFG2   A0A2S2R5J1   A0A0P6A4L5   A0A0P5ZYZ1   A0A0N8EGR5   A0A0P5QZN3   E9GIS4   A0A147BUV0   A0A293N253   A0A224YP23   A0A1E1XEW3   K7IVT5   A0A224YXK0   A0A443STX7   A0A023GDJ5   A0A443QDS8   V9K781   K1PK87  

Pubmed

19121390    22118469    26354079    24845553    25474469    26334808    + More
28004739    25401762    26823975    18362917    19820115    27129103    21282665    30249741    21347285    24508170    26830274    23537049    30329069    21292972    29652888    28797301    28503490    20075255    24402279    22992520   

EMBL

BABH01030078    BABH01030079    RSAL01000223    RVE43996.1    AGBW02009204    OWR51388.1    + More
KQ459602    KPI93479.1    KQ460615    KPJ13725.1    ODYU01001228    SOQ37152.1    NEVH01008214    PNF34561.1    PNF34560.1    KK852413    KDR24415.1    PNF34562.1    GEDC01025772    GEDC01000329    JAS11526.1    JAS36969.1    GECU01031077    JAS76629.1    GECU01033187    JAS74519.1    GECZ01028323    JAS41446.1    GECU01026322    JAS81384.1    GECU01034112    JAS73594.1    AJVK01018645    AJVK01018646    GEBQ01032187    GEBQ01005798    JAT07790.1    JAT34179.1    GFDF01004667    JAV09417.1    CVRI01000050    CRK99378.1    GBBI01003142    JAC15570.1    GFTR01008902    JAW07524.1    GBGD01000052    JAC88837.1    GBRD01002817    GBRD01002812    JAG63009.1    GBRD01002816    GBRD01002814    JAG63007.1    KQ414894    KOC59696.1    ACPB03015372    GEZM01012264    JAV93030.1    GBHO01025613    JAG17991.1    GDHC01017301    JAQ01328.1    GBRD01002815    GBRD01002813    JAG63008.1    GBHO01025614    GBHO01025610    JAG17990.1    JAG17994.1    GDHC01007761    JAQ10868.1    GBHO01017194    JAG26410.1    GDHC01013748    JAQ04881.1    GBHO01025616    JAG17988.1    GDHC01000097    JAQ18532.1    GBHO01027292    GBHO01025612    JAG16312.1    JAG17992.1    GBHO01025617    GBHO01025615    JAG17987.1    JAG17989.1    KQ971342    KYB27699.1    GDKW01002523    JAI54072.1    EFA02989.2    GL764132    EFZ18263.1    QOIP01000014    RLU14941.1    KQ983211    KYQ46638.1    ADTU01011777    ADTU01011778    KK107405    EZA51217.1    KQ979863    KYN18756.1    KQ977873    KYM99132.1    KQ976396    KYM92852.1    GEDV01004322    JAP84235.1    GEDV01004321    JAP84236.1    JH431584    KK115327    KFM64798.1    GDIP01058430    JAM45285.1    KB631743    ERL85715.1    GDIQ01169994    JAK81731.1    GDIQ01138207    JAL13519.1    GDIP01252105    JAI71296.1    GDIQ01096817    JAL54909.1    GDIP01141215    JAL62499.1    GDIP01031242    JAM72473.1    GDIQ01105565    JAL46161.1    MH712875    AYN64382.1    LRGB01000704    KZS16522.1    GDIQ01039442    JAN55295.1    GDIP01163809    JAJ59593.1    GDIP01134116    JAL69598.1    GDIP01142318    JAL61396.1    GDIQ01190189    GDIQ01190188    JAK61536.1    GDIQ01226428    GDIQ01226427    JAK25298.1    KZ288292    PBC29086.1    KQ981727    KYN37101.1    GDIP01157063    JAJ66339.1    GGMS01015797    MBY85000.1    GDIP01036082    JAM67633.1    GDIP01037131    JAM66584.1    GDIQ01028348    JAN66389.1    GDIQ01107962    JAL43764.1    GL732546    EFX80839.1    GEGO01001092    JAR94312.1    GFWV01021543    MAA46271.1    GFPF01007529    MAA18675.1    GFAC01001460    JAT97728.1    GFPF01007528    MAA18674.1    NCKV01000312    RWS30969.1    GBBM01003504    JAC31914.1    NCKU01009713    RWS01174.1    JW861122    AFO93639.1    JH816978    EKC22028.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053268    UP000053240    UP000235965    + More
UP000027135    UP000092462    UP000192223    UP000183832    UP000053825    UP000015103    UP000007266    UP000279307    UP000075809    UP000005205    UP000053097    UP000078492    UP000078542    UP000078540    UP000054359    UP000005203    UP000030742    UP000085678    UP000076858    UP000242457    UP000078541    UP000000305    UP000002358    UP000288716    UP000285301    UP000005408   

PRIDE

H9JDE2   

Pfam

PF00632   HECT        + More
PF02825   WWE
PF00096   zf-C2H2

Interpro

IPR018123   WWE-dom_subgr        + More
IPR011989   ARM-like       
IPR037197   WWE_dom_sf       
IPR035983   Hect_E3_ubiquitin_ligase       
IPR016024   ARM-type_fold       
IPR000569   HECT_dom       
IPR004170   WWE-dom       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF117839   SSF117839        + More
SSF48371   SSF48371       
SSF56204   SSF56204       
SSF57667   SSF57667       

Gene 3D

1.25.10.10     3.30.720.50    

CDD

cd00078  HECTc

ProteinModelPortal

H9JDE2   A0A437B0L8   A0A212FCE6   A0A194PL69   A0A194R8Z6   A0A2H1V9S7   + More
A0A2J7R148   A0A2J7R149   A0A067RUC7   A0A2J7R154   A0A1B6CDK3   A0A1B6HPM5   A0A1B6HIP0   A0A1B6EU11   A0A1B6I391   A0A1B6HFS4   A0A1B0DRJ3   A0A1B6ME64   A0A1W4XCN5   A0A1L8DSR1   A0A1J1IHY8   A0A023F2M2   A0A224X9E7   A0A069DYG2   A0A0K8TBZ6   A0A0K8TBT8   A0A0L7QMD7   T1HY39   A0A1Y1N832   A0A0A9XEA8   A0A146KYS7   A0A0K8TBV2   A0A0A9XLJ3   A0A146LSW2   A0A0A9YA47   A0A146L998   A0A0A9XGQ4   A0A146MHM7   A0A0A9X6F5   A0A0A9XDB1   A0A139WIF7   A0A0N7Z8S6   D6WKR6   E9IME8   A0A3L8D484   A0A151WFQ6   A0A158NCA7   A0A026W567   A0A151J6G5   A0A195CEA5   A0A195BW90   A0A131Z0H8   A0A131Z199   T1IVF8   A0A087TI59   A0A087ZT69   A0A0P5YJT4   U4U6X9   A0A1S3K667   A0A0P5LJN1   A0A0P5NSZ6   A0A0N7ZEX9   A0A0P5RS56   A0A0N8CDX9   A0A0P6ADL8   A0A0P5R4P5   A0A1S3K657   A0A1S3K6I9   A0A1S3K662   A0A1S3K781   A0A3G2KX41   A0A162CJF2   A0A0P6G2K6   A0A0N8ABG6   A0A0P5U745   A0A0P5SUR5   A0A0P5KJU8   A0A0N8AZX9   A0A2A3ED50   A0A195F9P5   A0A0P5DFG2   A0A2S2R5J1   A0A0P6A4L5   A0A0P5ZYZ1   A0A0N8EGR5   A0A0P5QZN3   E9GIS4   A0A147BUV0   A0A293N253   A0A224YP23   A0A1E1XEW3   K7IVT5   A0A224YXK0   A0A443STX7   A0A023GDJ5   A0A443QDS8   V9K781   K1PK87  

PDB

4Y07     E-value=1.85055e-26,     Score=299

KEGG

101736311    K10590 E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26] | (RefSeq) E3 ubiquitin-protein ligase TRIP1

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0004842   GO:0008270   GO:0016874   GO:1901315   GO:0006974   GO:0006511   GO:0016607   GO:0016740   GO:0003676   GO:0016021   GO:0032259   GO:0019205   GO:0005739   GO:0016776   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

Length:

698

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0642699999999999

Exp number, first 60 AAs:

0.01907

Total prob of N-in:

0.00329

outside

1  -  698

 

 

Pi

65.738147

Theta

37.822128

Tajima's D

-1.555552

CLR

4123.512468

CSRT

0.0530473476326184

Interpretation

Uncertain