Gene

KWMTBOMO09125

Pre Gene Modal

BGIBMGA007539

Annotation

PREDICTED:_E3_ubiquitin-protein_ligase_TRIP12_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr15(+):11744281-11758995      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 2.629

CDS

ATGCCGCAGCCGCAGCCGGCCTCTACTCGAAAAGAAAAACGAGGCAAAACCAGTCTGGGTTCCTGTGCCAGTACTGGTGCTGCCACTAGCCGCTCCCACGCCCAGCCTCTAACCACGGGTGCCATAGCATCCACGTCCACCACACCACCTGCTCAAGCTGCAGCTGTCTCGATGCCTGACAATGCTGCAAGTGACGTCAAGCCTAAAGTGGGTGGCATGACGTCAGCGGAGGAGTGTGGGGGCGCGGGCGGGGCGGGGCTGGGCGGCGCGGCGACGCTGGCCGAGGAGTCGTCGTCCGAGGAGGGCGAGGTGGGCCGGCTGCAGGCGCTGCTAGAGGCGCGCGGCCTCCCGCCGCACCTGCTCGGCGCGCTCGGGCCTCGCATGCAGCACCTCCTGCACCGGACAGTCACCGCTAACTCGGCGGCTTCTAAAGCAGCTCAACTGCTCGCTGGCCTCCAGGCAACCGGCGACGAAGGCCAACAGCTTCAAGCCGTCATAGAAATGTGCCAACTTCTCGTTATGGGCAACGAGGACACGCTCGCCGGCTTCCCGGTCCGACAAGTCGTTCCCGCTCTCGTTAACCTGCTCGCTGCCGAACATAACTTTGACATGATGAACCACGCGTGCCGCGCGCTGACGTACATGCTGGAGGCGCTGCCCCGCAGCAGCGGCGCCGTGGCGCTGGCCGTGCCCGCCTTCCTCGACAAGCTGCAGGCCATCACGTGCATGGACGTCGCCGAGCAGAGCCTCACCGCGCTCGACATGCTGTCCCGCAGACACGCCAAAGCCATCCTGCAAGCGCGAGGTGTATCGGCCTGCCTGACCTACCTGGACTTCTTCTCCATAAACGCGCAACGTGCCGCGCTCTCCATCACCGCTAATTGTTGCCAAAACCTCACTGCAGATGAATTTCACCTTGTCCGAGAATCTCTACAATTGCTTGCTAATAGACTAACTCAACAAGACAAAAAGTCAGTGGAGTGCGTTTGTCTCGCATTCTCGCGGCTCGTGGACAGCTTCCAGCACGACCCGGCACGCTTGCAGGAAATCGCCACTCCGGAATTACTTACTAATCTACAACAACTTTTGGTGGTGCAGCCGCCACTGATATCGGGCGGGACGTTCATCATGGTGCTGCGGCTGCTGTGGCTCATGTGCGGCGCCTGCCCGCAGCTCGCGCTCGCGCTGCACCAGCGGTCCATCGCCGACACGCTGCTCTGTCTGCTCACCGGCTCCACGCTACATCAGGAGCAAGTGGAGCTGATACCGCGCCTGCCGCAAGAGCTGTATGAGATCACATGCCTCATCGGAGAGTTGATGCCGCGGCTACCCACCGACGGGATCTTCGCGGTGGACGCACATCTCGACCGGCCCTGGTCCACCAGCACCGAGCGAACTGCGCATTGGCAGTGGCGAGACGATAGAGGTGCGGCGGCGGGCGAGGAGGAGGTGTGCCTGAGCACGCTGGGCCGCTCCTACACGGTGGACCTCACCGCCATGCAGCAGCTCAACGAACACACCGGCACCGCGCGGCCCGTGCAGCGCCTCGCCCCCCCGCACGCACCCCACGCCGCCGCCGCAGCCGCCGCGCCCGATCCGCGCATCAGCATGGTGCGGTCGAACCCGTCTCTAATCCGCGCTCTGCTGGCTGTCCTCCACGAAGTGTACTGGAGCTCGGCGGGACCGGCCGTGCGCTCGCAGGCTCTGAAGGCCATACTGCGCTGCGTCTATTACGCCGATGCGGCGCTACTGCGACAAGTTCTAAAGATGCAGGTGATATCGTCTCACATCGCCGGTATGATGGCTTCTAGCGACCTGCGCATTGTTGTGGGATCGTTGCAGCTGGCGGAGATACTGATGCAGCGCTTACCCGAAGAGATGGGTGCTCAGTTCAGACGCGAGGGCGTGCTGCATCAGGTCGCGCAGCTCGCCGCACCGCATTCCACCACACAGAACTTGCAAAAGTCACCGAATGGCCCCAATGCACGCACCAGCGGTGGGGCATCCCCTCCAACATCATCAACGGCTTCGCTCGAGCACAACAATCTTTCCATGGCATTTTCTGCTTCAGGTTCATTTGTGGCCACTTCGCTACCGAGCGGTAGCGACGTGAGTGGATCGGAACCGGGTCCTGCATCTGCTTCTACACATCCCCAGTTACCAACTTCAGTGCACAGGTCGGGCAGTCCCCTGCAGCTGGCTGAGATGTTGAAACGTAAGCGGGCTATAAAGCGGAGCGGCGCAGGCGGCGGGCGACACGCGCGGCGCCGCGACGACCCCGTGCACGCGCCCGCGCCGCACCACGCGTCGCATCACGCGCCCTCGCCGCACGGAGCGAGCAGTTCGGGCGGAGGGCGCGGCGCCGGGCGGCCCAGCGGCGCGTCCAAGACCGCGTCGTTCCTGTCGTCGCTGAACCCGTCGCGCTGGGGCCGCGCGCCGCACCAGCACAAGGACACGGCGCTGCTCGCCTCGCCGCACGCCAGCGCCAACCTCACCGTGCAGAACAAAGAGAAAGTCCGCGAGTGGATTTCGTGGTCGGCGCGTCGGCTGCGCTGCGAGTGGGGAGCGCTGGGCGGCGGCGCCGGGGCGCTGGAGCAGCTGGGAGCGCTGGCGGCCGCGCTGCCGCACGCTGCGCACTCGCGCGCCGCCCTGGCACATCTCCGCGACACGCTGCTGCATCACGACGTCTCGCCCTTCGAGGTGAACCATTCCGGAGTATTGGGCGCCCTGCACCAATACCTAACTGGCTTCGATATGGAAGTGGATGGTTTGGAAAAGCGCGACGGCGATGGCGAAGGACAGGAGTCCGCTGATTTGGTGCAAGCGTGTGAAGAGCGACTGCGTTTATTCTTACATGTGTTTGCTGAGATGCCCATTGAACCTGAAGTAAACGATTGGAAAGAGTCGTTGGGCAGCAGCACGGCCTTGTGTGCGCTGGTGGCGAAGGTGAACGCGTGCGTGTCGCATCTCGAGCAGTTTCCGGTGCGAGTCCACGACCTACCGGCCCGTCCCGCCACGTCCGCTCTTAAATTCTTCAACACGCACCAGCTCATGTGTGATCTCAAACGTCATCCTTCGTGCAACACTTTGAAGCAATGGAAGGGTGGTGTAGTACGAATAGACCCATTAGCTTTAGTTCAAGCCATCGAGAGATACCTGGCGCAGCGCGGGTACGCCCAGGGCCGCACGCGCTCGGACTCTGCGGGCGCGCACTCGGACGACGAGCCCGCCTCCGATGACGACGTCGACGACGCCCTGCCCGCGCCGCCGCAGCCCACCAACGAGTCAGTCACGTTTCTCGCTTCTATGCCTTATTGA

Protein

MPQPQPASTRKEKRGKTSLGSCASTGAATSRSHAQPLTTGAIASTSTTPPAQAAAVSMPDNAASDVKPKVGGMTSAEECGGAGGAGLGGAATLAEESSSEEGEVGRLQALLEARGLPPHLLGALGPRMQHLLHRTVTANSAASKAAQLLAGLQATGDEGQQLQAVIEMCQLLVMGNEDTLAGFPVRQVVPALVNLLAAEHNFDMMNHACRALTYMLEALPRSSGAVALAVPAFLDKLQAITCMDVAEQSLTALDMLSRRHAKAILQARGVSACLTYLDFFSINAQRAALSITANCCQNLTADEFHLVRESLQLLANRLTQQDKKSVECVCLAFSRLVDSFQHDPARLQEIATPELLTNLQQLLVVQPPLISGGTFIMVLRLLWLMCGACPQLALALHQRSIADTLLCLLTGSTLHQEQVELIPRLPQELYEITCLIGELMPRLPTDGIFAVDAHLDRPWSTSTERTAHWQWRDDRGAAAGEEEVCLSTLGRSYTVDLTAMQQLNEHTGTARPVQRLAPPHAPHAAAAAAAPDPRISMVRSNPSLIRALLAVLHEVYWSSAGPAVRSQALKAILRCVYYADAALLRQVLKMQVISSHIAGMMASSDLRIVVGSLQLAEILMQRLPEEMGAQFRREGVLHQVAQLAAPHSTTQNLQKSPNGPNARTSGGASPPTSSTASLEHNNLSMAFSASGSFVATSLPSGSDVSGSEPGPASASTHPQLPTSVHRSGSPLQLAEMLKRKRAIKRSGAGGGRHARRRDDPVHAPAPHHASHHAPSPHGASSSGGGRGAGRPSGASKTASFLSSLNPSRWGRAPHQHKDTALLASPHASANLTVQNKEKVREWISWSARRLRCEWGALGGGAGALEQLGALAAALPHAAHSRAALAHLRDTLLHHDVSPFEVNHSGVLGALHQYLTGFDMEVDGLEKRDGDGEGQESADLVQACEERLRLFLHVFAEMPIEPEVNDWKESLGSSTALCALVAKVNACVSHLEQFPVRVHDLPARPATSALKFFNTHQLMCDLKRHPSCNTLKQWKGGVVRIDPLALVQAIERYLAQRGYAQGRTRSDSAGAHSDDEPASDDDVDDALPAPPQPTNESVTFLASMPY

Catalytic Activity

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Uniprot

H9JDE2   A0A194PL69   A0A212FCE6   A0A437B0L8   S4NNH1   A0A194R8Z6   + More
A0A1Y1N5J1   A0A1Y1N832   U4U6X9   A0A139WIF7   D6WKR6   N6UGN3   T1IVF8   E9GIS4   A0A1B6I391   A0A3Q0DAY5   A0A452CP65   L5L065   A0A452CP31   A0A452CP71   A0A2Y9MNR1   A0A2Y9SPU4   A0A2Y9N2W2   A0A2Y9MNR6   A0A452CP76   A0A3Q7QJ16   A0A2Y9SS94   A0A2Y9SNU0   A0A2Y9IRG3   A0A3Q7VYD9   K9IUR6   I3LK74   A0A3Q7QIX2   A0A3Q7RY28   A0A3Q7VER3   A0A287AHR9   A0A2Y9N2X3   A0A3Q7QUE1   A0A2Y9SPU9   A0A2Y9IS02   A0A2Y9IS58   A0A1D5Q1A6   A0A2K5W179   A0A0B8RZ14   A0A287ABS2   A0A287BDL0   A0A2Y9RMZ8   A0A3Q7TLD2   A0A3Q7U486   A0A3Q7SK99   A0A383YVE0   A0A383YV63   A0A3Q7VER9   A0A2Y9MRQ8   A0A2K6CT33   A0A384C192   A0A2I2Y313   A0A2K5XT25   A0A452EH82   A0A2Y9RQ91   A0A2R9CE95   A0A2I3MF76   A0A2K6NWP9   A0A2Y9GMU1   A0A2Y9GHP0   H2QJK1   A0A2Y9ISV5   A0A3Q7SK96   A0A2Y9MMT9   A0A3Q7UGN8   I3MNV5   A0A341B3L1   A0A452EHB6   A0A2K5DK90   A0A2K5DK54   A0A2Y9FQC0   A0A2K6NWR1   M3WFL9   A0A2Y9IRZ0   A0A2Y9MX55   A0A2K5HEH5   A0A2K6V8K8   A0A383YVM5   A0A2Y9MMS9   A0A287CS44   A0A2I2YZ06   A0A341B0T4   A0A341B493   A0A452EH96   F7D7S2   A0A3Q2HJ91   A0A2Y9RN03   A0A3Q7QUF3   A0A3Q7QJ00   A0A2Y9FMY9   A0A2I2V4P8   K7DNP2   A0A2K5S383   A0A2K5HEI3  

Pubmed

19121390    26354079    22118469    23622113    28004739    23537049    + More
18362917    19820115    21292972    26319212    28071753    23258410    17431167    30723633    22398555    22722832    25362486    16136131    17975172    19892987   

EMBL

BABH01030078    BABH01030079    KQ459602    KPI93479.1    AGBW02009204    OWR51388.1    + More
RSAL01000223    RVE43996.1    GAIX01013931    JAA78629.1    KQ460615    KPJ13725.1    GEZM01012265    JAV93029.1    GEZM01012264    JAV93030.1    KB631743    ERL85715.1    KQ971342    KYB27699.1    EFA02989.2    APGK01021341    APGK01021342    KB740314    ENN80905.1    JH431584    GL732546    EFX80839.1    GECU01026322    JAS81384.1    KB030407    ELK17134.1    GABZ01000332    JAA53193.1    AEMK02000101    JSUE03009783    JSUE03009784    JSUE03009785    JSUE03009786    AQIA01016162    AQIA01016163    AQIA01016164    AQIA01016165    AQIA01016166    GBZA01000686    JAG69082.1    DQIR01122054    HDA77530.1    CABD030019002    CABD030019003    CABD030019004    CABD030019005    CABD030019006    CABD030019007    CABD030019008    CABD030019009    CABD030019010    CABD030019011    LWLT01000002    AJFE02075331    AJFE02075332    AJFE02075333    AJFE02075334    AJFE02075335    AJFE02075336    AJFE02075337    AJFE02075338    AJFE02075339    AJFE02075340    AHZZ02004663    AACZ04056628    AGTP01044278    AGTP01044279    AGTP01044280    AGTP01044281    AGTP01044282    AANG04002752    GABE01000120    JAA44619.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000283053    UP000053240    UP000030742    + More
UP000007266    UP000019118    UP000000305    UP000189706    UP000261681    UP000010552    UP000248483    UP000248484    UP000286641    UP000248482    UP000286642    UP000008227    UP000006718    UP000233100    UP000248480    UP000286640    UP000233120    UP000261680    UP000001519    UP000233140    UP000291000    UP000240080    UP000028761    UP000233200    UP000248481    UP000002277    UP000005215    UP000252040    UP000233020    UP000011712    UP000233080    UP000233220    UP000002281    UP000233040   

PRIDE

H9JDE2    I3LK74   

Pfam

PF00632   HECT        + More
PF02825   WWE

Interpro

IPR018123   WWE-dom_subgr        + More
IPR011989   ARM-like       
IPR037197   WWE_dom_sf       
IPR035983   Hect_E3_ubiquitin_ligase       
IPR016024   ARM-type_fold       
IPR000569   HECT_dom       
IPR004170   WWE-dom       

SUPFAM

SSF117839   SSF117839        + More
SSF48371   SSF48371       
SSF56204   SSF56204       

Gene 3D

1.25.10.10     3.30.720.50    

CDD

cd00078  HECTc

ProteinModelPortal

H9JDE2   A0A194PL69   A0A212FCE6   A0A437B0L8   S4NNH1   A0A194R8Z6   + More
A0A1Y1N5J1   A0A1Y1N832   U4U6X9   A0A139WIF7   D6WKR6   N6UGN3   T1IVF8   E9GIS4   A0A1B6I391   A0A3Q0DAY5   A0A452CP65   L5L065   A0A452CP31   A0A452CP71   A0A2Y9MNR1   A0A2Y9SPU4   A0A2Y9N2W2   A0A2Y9MNR6   A0A452CP76   A0A3Q7QJ16   A0A2Y9SS94   A0A2Y9SNU0   A0A2Y9IRG3   A0A3Q7VYD9   K9IUR6   I3LK74   A0A3Q7QIX2   A0A3Q7RY28   A0A3Q7VER3   A0A287AHR9   A0A2Y9N2X3   A0A3Q7QUE1   A0A2Y9SPU9   A0A2Y9IS02   A0A2Y9IS58   A0A1D5Q1A6   A0A2K5W179   A0A0B8RZ14   A0A287ABS2   A0A287BDL0   A0A2Y9RMZ8   A0A3Q7TLD2   A0A3Q7U486   A0A3Q7SK99   A0A383YVE0   A0A383YV63   A0A3Q7VER9   A0A2Y9MRQ8   A0A2K6CT33   A0A384C192   A0A2I2Y313   A0A2K5XT25   A0A452EH82   A0A2Y9RQ91   A0A2R9CE95   A0A2I3MF76   A0A2K6NWP9   A0A2Y9GMU1   A0A2Y9GHP0   H2QJK1   A0A2Y9ISV5   A0A3Q7SK96   A0A2Y9MMT9   A0A3Q7UGN8   I3MNV5   A0A341B3L1   A0A452EHB6   A0A2K5DK90   A0A2K5DK54   A0A2Y9FQC0   A0A2K6NWR1   M3WFL9   A0A2Y9IRZ0   A0A2Y9MX55   A0A2K5HEH5   A0A2K6V8K8   A0A383YVM5   A0A2Y9MMS9   A0A287CS44   A0A2I2YZ06   A0A341B0T4   A0A341B493   A0A452EH96   F7D7S2   A0A3Q2HJ91   A0A2Y9RN03   A0A3Q7QUF3   A0A3Q7QJ00   A0A2Y9FMY9   A0A2I2V4P8   K7DNP2   A0A2K5S383   A0A2K5HEI3  

KEGG

101736311    K10590 E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26] | (RefSeq) E3 ubiquitin-protein ligase TRIP1

GO

GO:0004842   GO:0008270   GO:0016874   GO:1901315   GO:0006974   GO:0006511   GO:0016607   GO:0016740   GO:0046966   GO:0045995   GO:2000780   GO:0005488   GO:0032259   GO:0019205   GO:0005739   GO:0016776   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

Length:

1105

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.23358

Exp number, first 60 AAs:

0.00059

Total prob of N-in:

0.00617

outside

1  -  1105

 

 

Pi

3.870532

Theta

182.319091

Tajima's D

-1.791728

CLR

733.089298

CSRT

0.0286485675716214

Interpretation

Possibly Positive selection