SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO09097  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA007522
Annotation
transcription_factor-like_protein_[Bombyx_mori]
Full name
COP9 signalosome complex subunit 6      
Location in the cell
Cytoplasmic   Reliability : 0.918
 

Sequence

CDS
ATGTCAAGTGCTGATCGAATTGATTTCGAAATGGAAGTGGAAGTAGAGAGTGCATCTTCAGGTCCGCCGATTGAAGTGCCTAACCCAACATCCCCGGCGCCTACAACACCAGGCAGCAATAAGAGTGTAGTAGTTACGACTGCTACAGCCGGTTCGGTGACCGTCTCTCTCCATCCTTTAGTTATTATGAATGTTTCAGAACATTGGACACGACTTAAGGCACAGGAAGGCTTTCCTCAAACAGTTGTTGGAGCTTTAATTGGGAAGCAAAAAGGTCGCAACATTGAAGTAATGAATTCATTTGAATTAGTGTTCAGTATGATTGATGGAGACATTATTATAGATAGAGATTATTATAATATGAAAGAGGAACAATTCAAACAAGTGTTTTCTGACATGGATTTCCTCGGATGGTATACAACTGGAGATGCTCCCTCAGAACGTGACATCGCAGTTCACAGACAGATCTGTGACATTAATGAGTGTCCTGTGATGTTGATGTTGAATCCGGCAGGCAGAAATGGTGATCAATTACCGGTAGTTTTGTATGAATCAGTAATTGATGTGGTTAATGGTCGCGCCACAATGCTACTAGCACCTTTAACATATACATTAGCCGCTGAAGAGGCTGAGAGAATTGGAGTAGATCATGTTGCCAGAGTTTCATCTGGAGAAGCTGCTCTCAATAGTTTAGTTGCCGAACATCTGACTGCACAAAGATCAGCTATAAAAATGTTAGTTTCTCGTGTACGGGCCGTACTTGCGACAGTACGCGCTATAAGGGATGGTAAACTTCAGCCTCGACCGGCTTTACTAAGGGAGGCGCGTGCTCTCGCCAACAGATTACCTCTGTTGACTTCACAGCAGTTCCGGACACATTTCTATAATCAATGCAACGATGTAGCCCTAATGACATACTTAGGGACGATCACGAAGGGCTGCAACGCTATCAATCAGCTTGTGAATAGATTCAACGTGCTCTACGACAGACAGGGCATGGGAAGGCGCATGCGAGGACTCTTCTTTTAG
Protein
MSSADRIDFEMEVEVESASSGPPIEVPNPTSPAPTTPGSNKSVVVTTATAGSVTVSLHPLVIMNVSEHWTRLKAQEGFPQTVVGALIGKQKGRNIEVMNSFELVFSMIDGDIIIDRDYYNMKEEQFKQVFSDMDFLGWYTTGDAPSERDIAVHRQICDINECPVMLMLNPAGRNGDQLPVVLYESVIDVVNGRATMLLAPLTYTLAAEEAERIGVDHVARVSSGEAALNSLVAEHLTAQRSAIKMLVSRVRAVLATVRAIRDGKLQPRPALLREARALANRLPLLTSQQFRTHFYNQCNDVALMTYLGTITKGCNAINQLVNRFNVLYDRQGMGRRMRGLFF

Summary

Description
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).
Subunit
Component of the CSN complex, probably composed of cops1, cops2, cops3, cops4, cops5, cops6, cops7, cops8 and cops9.
Similarity
Belongs to the peptidase M67A family. CSN6 subfamily.
Keywords
Cytoplasm   Nucleus   Signalosome  
Feature
chain  COP9 signalosome complex subunit 6
EMBL
BABH01030112    DQ311258    ABD36203.1    KQ460615    KPJ13697.1    AK401713    + More
KQ459602    BAM18335.1    KPI93446.1    ODYU01011781    SOQ57721.1    GDQN01004841    JAT86213.1    AGBW02011160    OWR47120.1    JTDY01000861    KOB75640.1    RSAL01000065    RVE49422.1    NEVH01006723    PNF36983.1    KK852634    KDR19771.1    DS497702    EFA12663.1    GEZM01074861    JAV64450.1    KZ288310    PBC28627.1    GECU01023945    GECU01009297    JAS83761.1    JAS98409.1    GECZ01008627    JAS61142.1    KQ435969    KOX67875.1    KQ414583    KOC70767.1    GBHO01036231    GBHO01012198    GBRD01007120    GDHC01021558    GDHC01017720    GDHC01004598    JAG07373.1    JAG31406.1    JAG58701.1    JAP97070.1    JAQ00909.1    JAQ14031.1    GDKW01001708    JAI54887.1    ACPB03017525    GAHY01001519    JAA75991.1    GECL01001160    JAP04964.1    KQ434786    KZC05096.1    GBGD01002230    JAC86659.1    DS235049    EEB10993.1    JH431723    GBBM01001838    JAC33580.1    JO842932    AEO34549.1    GFAC01004693    JAT94495.1    NEDP02000041    OWF56821.1    GFPF01006905    MAA18051.1    GEDV01007209    JAP81348.1    GACK01005496    JAA59538.1    GBBI01000653    JAC18059.1    GFTR01004985    JAW11441.1    GEFH01005111    JAP63470.1    CH478240    EAT33443.1    GAPW01002260    JAC11338.1    GL769399    EFZ10439.1    KK107020    EZA62501.1    AAZX01005358    GDAI01002043    JAI15560.1    UFQS01000317    UFQS01001464    UFQT01000317    UFQT01001464    SSX02810.1    SSX30668.1    JXUM01103889    KQ564842    KXJ71657.1    KK107256    QOIP01000006    EZA54278.1    RLU21226.1    NNAY01000354    OXU28958.1    GL888384    EGI61900.1    KQ976417    KYM89814.1    KQ981953    KYN32481.1    ADTU01021753    KQ982766    KYQ50990.1    KQ978438    KYM93981.1    KQ980503    KYN15792.1    GEFM01006809    JAP68987.1    RLU21945.1    DS231890    EDS43805.1    GL436428    EFN72006.1    ABJB010098962    ABJB010591610    ABJB010816375    DS816156    EEC11415.1    GEDC01029404    JAS07894.1    GFDL01011535    JAV23510.1    JH817877    EKC33739.1    GANO01000746    JAB59125.1    MWRG01017377    PRD23550.1    BT126822    AEE61784.1    APGK01040869    KB740984    ENN76312.1    GFDF01004566    JAV09518.1    GGLE01005361    MBY09487.1    GFWV01010486    MAA35215.1    LJIG01022557    KRT79937.1    GBYB01009856    JAG79623.1    KB203567    ESO83905.1    AMQN01014936    KB311434    ELT89268.1    KA647927    AFP62556.1    BC068673    GL732584    EFX74250.1    CH902617    EDV44193.1    ATLV01021357    KE525317    KFB46386.1    AHAT01024680    JRES01001062    JRES01000065    KNC25907.1    KNC34432.1    ADMH02001270    ETN63280.1    JXJN01024713    CH964232    EDW80920.1    CCAG010015463    EZ423288    ADD19564.1    GGFK01010855    MBW44176.1    GGFK01010908    MBW44229.1    GDIP01053377    GDIQ01036832    LRGB01000725    JAM50338.1    JAN57905.1    KZS16283.1   
Pfam
PF01398   JAB        + More
PF13012   MitMem_reg
Interpro
IPR024969   Rpn11/EIF3F_C        + More
IPR033859   MPN_CSN6       
IPR037518   MPN       
IPR000555   JAMM/MPN+_dom       
PDB
4WSN     E-value=3.45562e-95,     Score=888

Ontologies

Topology

Subcellular location
Cytoplasm  
Nucleus  
Length:
342
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.555370000000001
Exp number, first 60 AAs:
0.36549
Total prob of N-in:
0.02620
outside
1  -  342
 
 

Population Genetic Test Statistics

Pi
217.077395
Theta
186.683539
Tajima's D
0.585578
CLR
0.147818
CSRT
0.543072846357682
Interpretation
Uncertain
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