SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO09089  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA007516
Annotation
PREDICTED:_elongation_factor_1-alpha_2_[Papilio_xuthus]
Location
Bomo_Chr15(+):11084729-11088242      View in EpiBrowser
Full name
Elongation factor 1-alpha       + More
Elongation factor 1-alpha 2      
Location in the cell
Cytoplasmic   Reliability : 4.325
 

Sequence

CDS
ATGGGTAAAGAGAAGACTCATATCAACATCGTCGTCATCGGCCATGTGGACTCTGGAAAGTCCACTACTACCGGCCATCTCATCTACAAGTGCGGCGGCATTGATAAACGTACAATCGAGAAGTTTGAGAAAGAAGCTCAAGAGATGGGCAAGGGCTCCTTCAAGTATGCTTGGGTATTGGACAAGCTAAAGGCGGAACGCGAACGCGGTATCACCATTGACATAGCTCTCTGGAAGTTTGAAACCAGCAAATACTACGTCACCATTATTGATGCTCCCGGTCATAGAGATTTCATTAAGAACATGATCACGGGTACTTCCCAGGCTGATTGCGCAGTACTGATCGTGGCAGCCGGAACTGGCGAGTTCGAAGCCGGTATCAGTAAGAATGGACAGACTCGCGAACACGCCCTGCTTGCTTTCACTCTTGGCGTAAAACAACTTATTGTCGGCGTGAATAAAATGGACTCTACCGAACCGCCTTACCATGAGGCTCGCTATGAAGAGATTAAGAAAGAAGTGTCTTCTTACATTAAGAAAATTGGTTACAATCCCGCTACTGTGGCGTTCGTACCGATATCTGGCTGGCACGGTGACAATATGCTGGAGCCTTCTGATAAGATGCCTTGGTTCAAGGGGTGGACCATCGATCGCAAGGACGGCAAAGTCGAGGGAAAATGTCTCATCGAGGCGCTCGATGCGATACAGCCTCCGTCACGGCCGACTGAGAAGCCCCTTCGCTTGCCTCTTCAGGACGTGTACAAGATAGGAGGAATCGGAACGGTGCCAGTTGGACGAGTGGAGACAGGAATTCTCAAGCCTGGTATGGTTGTGGTATTTGCTCCGGCAGCTATTACCACCGAAGTTAAGTCTGTTGAGATGCACCACGAGGCACTGCAAGAGGCGATGCCCGGCGATAACGTCGGCTTCAACGTCAAGAACGTATCGGTGAAAGAACTGCGTCGCGGCTACGTTGCTGGCGATTCTAAGAACGCACCACCCAAAGGCGCTTCCGACTTCACTGCTCAGGTGATTGTGCTCAACCACCCGGGACAAATCAGCAACGGGTATACTCCGGTGCTTGATTGTCACACCGCTCATATCGCCTGCAAGTTCGCCGAGATCAAGGAGAAGTGCGACCGCCGTACCGGAAAAACAACCGAAGTGGATCCAAAGTCGATCAAGTCTGGAGACGCAGCCATCGTGACTCTGGTGCCAACAAAGCCCCTGTGTGTCGAATCCTTCCAGGAGTTCCCTCCGCTCGGTCGGTTTGCTGTGCGCGACATGCGTCAGACTGTCGCCGTGGGTGTCATCAAGAGTGTGACATTCAAAGAAGTGACTACTGGTAAAATTACCAAAGCCGCCGAGAAGGCCCAGAAGAAAAAATAA
Protein
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYHEARYEEIKKEVSSYIKKIGYNPATVAFVPISGWHGDNMLEPSDKMPWFKGWTIDRKDGKVEGKCLIEALDAIQPPSRPTEKPLRLPLQDVYKIGGIGTVPVGRVETGILKPGMVVVFAPAAITTEVKSVEMHHEALQEAMPGDNVGFNVKNVSVKELRRGYVAGDSKNAPPKGASDFTAQVIVLNHPGQISNGYTPVLDCHTAHIACKFAEIKEKCDRRTGKTTEVDPKSIKSGDAAIVTLVPTKPLCVESFQEFPPLGRFAVRDMRQTVAVGVIKSVTFKEVTTGKITKAAEKAQKKK

Summary

Description
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Similarity
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
Keywords
Complete proteome   Cytoplasm   Elongation factor   GTP-binding   Nucleotide-binding   Phosphoprotein   Protein biosynthesis   Reference proteome  
Feature
chain  Elongation factor 1-alpha
Uniprot
H9JDB9   A0A2H1WDC6   A0A3S2TNN4   A0A2A4JZ61   A0A194RCQ3   A0A212EKY6   + More
W8BCW3   A0A1S3DCE5   A9XXA7   H9J271   A0A182MBB0   A0A0K8TZP3   A0A139WNV6   A0A0A1WJ43   A0A0A0QY84   A0A182V4W0   A0A182TV27   A0A182KR72   A0A182X3V3   Q7PT29   A0A182I369   P29520   A0A1Q3F505   A0A194PP74   A0A0K8TPH8   A0A0N1PF32   A0A1Q3F4X7   A0A0K8TN69   W5JEK7   T1PCL0   B0WQ61   I4DLT8   L7WID6   A0A0K2CTM2   A0A336KP24   A0A0M4EGZ9   A0A1A9XNA3   T1DMZ2   A0A2M3ZY17   A0A182FHI6   W5JJ91   A0A182F7Q8   A0A182GCR7   A0A3B0EBP7   A0A1B0BS76   A0A1Q3G3C8   A0A1J1IE44   A0A1A9ZUN3   A0A2A4JGU8   A0A1I8PVF8   B2DBL0   A0A1A9WF65   J9HYQ9   A0A182GHS1   A0A1A9W6Y1   A0A1A9V2G9   A0A182JBL5   A0A1A9ZYJ8   D3TNV8   Q1HR88   A0A0Q4U618   A0A182NSM3   A0A182QFB2   A0A1B0C5C9   A0A2U6X9K6   A0A0U4CK92   A0A069DZ22   A0A023FBG1   B4M0Y1   D6WKQ3   A0A0L7LTH3   A0A385AAY2   A0A291L1Q9   R4G8S8   A0A182MKN9   A0A182R8C4   A0A3B0K4V0   Q297R9   B4G2Y2   A0A182P0C0   A0A0B5L5V8   A0A1W4VVS6   B4QT88   E0D8P8   A0A385AAX8   B4IJ22   B3P515   A4V3Q6   B4PP14   P05303   A0A224XC81   E2J7D9   A0A182YLI8   B4JH67   A0A182VS18   A0A182UTJ1   A0A182WVW6   F5HL97   A0A182HZ72   B4N8S9  
Pubmed
19121390    26354079    22118469    24495485    18154650    18362917    + More
19820115    25830018    20966253    12364791    14747013    17210077    8441684    26369729    20920257    23761445    25315136    22651552    26263512    26483478    18712529    17510324    20353571    17204158    26694822    26334808    25474469    17994087    26227816    28964897    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    3131735    3135536    25244985   
EMBL
BABH01030127    ODYU01007902    SOQ51085.1    RSAL01000040    RVE50997.1    NWSH01000353    + More
PCG77099.1    KQ460615    KPJ13686.1    AGBW02014166    OWR42156.1    GAMC01007440    JAB99115.1    EU016386    ABV68853.1    BABH01007426    JQ638952    AFJ44727.1    AXCM01017070    GDHF01032773    GDHF01032377    JAI19541.1    JAI19937.1    KQ971307    KYB29556.1    GBXI01015208    GBXI01010971    JAC99083.1    JAD03321.1    KM027246    AIU94615.1    AAAB01008807    EAA04644.4    APCN01000199    D13338    GFDL01012401    JAV22644.1    KQ459597    KPI95107.1    GDAI01001306    JAI16297.1    KQ461187    KPJ07349.1    GFDL01012424    JAV22621.1    GDAI01002027    JAI15576.1    ADMH02001732    ETN61259.1    KA646497    AFP61126.1    DS232034    EDS32715.1    AK402256    BAM18878.1    KC007373    AGC82213.1    KT218669    ODYU01003719    ALA09389.1    SOQ42848.1    UFQS01000679    UFQT01000679    SSX06137.1    SSX26493.1    CP012526    ALC45508.1    GAMD01003315    JAA98275.1    GGFK01000074    MBW33395.1    ADMH02001358    GGFL01004298    ETN62859.1    MBW68476.1    JXUM01054558    KQ561827    KXJ77411.1    RBVL01000042    RKO12866.1    JXJN01019543    GFDL01000730    JAV34315.1    CVRI01000047    CRK98525.1    NWSH01001631    PCG70643.1    AB264694    BAG30769.1    CH477381    EJY57625.1    JXUM01064419    JXUM01064420    KQ562297    KXJ76212.1    CCAG010021078    EZ423110    ADD19386.1    DQ440206    CH477217    ABF18239.1    EJY57378.1    LMMH01000027    KQO52249.1    AXCN02000234    JXJN01025928    KX353923    ANS53407.1    KU218668    ALX00048.1    GBGD01001395    JAC87494.1    GBBI01000012    GEMB01001277    JAC18700.1    JAS01877.1    CH940650    EDW67392.1    KQ971342    EFA03028.1    JTDY01000116    KOB78760.1    MH592940    AXL66192.1    KY809859    ATI09807.1    ACPB03005610    GAHY01000447    JAA77063.1    AXCM01000836    OUUW01000005    SPP81029.1    CM000070    EAL28136.1    CH479179    EDW24177.1    KM923784    AJG43843.1    CM000364    EDX15150.1    AB583233    BAJ15871.1    MH592933    AXL66185.1    CH480846    EDW50975.1    CH954182    EDV52929.1    AE014297    AAN14285.1    CM000160    EDW99250.1    X06870    BT015202    GFTR01006429    JAW09997.1    HP429357    ADN29857.1    CH916369    EDV92758.1    AAAB01008888    EGK97058.1    APCN01005504    CH964232    EDW81530.1   
Proteomes
UP000005204    UP000283053    UP000218220    UP000053240    UP000007151    UP000079169    + More
UP000075883    UP000007266    UP000075903    UP000075902    UP000075882    UP000076407    UP000007062    UP000075840    UP000053268    UP000000673    UP000095301    UP000002320    UP000092553    UP000092443    UP000069272    UP000069940    UP000249989    UP000276569    UP000092460    UP000183832    UP000092445    UP000095300    UP000091820    UP000008820    UP000078200    UP000075880    UP000092444    UP000051797    UP000075884    UP000075886    UP000008792    UP000037510    UP000015103    UP000075900    UP000268350    UP000001819    UP000008744    UP000075885    UP000192221    UP000000304    UP000001292    UP000008711    UP000000803    UP000002282    UP000076408    UP000001070    UP000075920    UP000007798   
PRIDE
H9JDB9    H9J271    P29520    A4V3Q6    P05303   
Pfam
PF00009   GTP_EFTU        + More
PF03144   GTP_EFTU_D2
PF03143   GTP_EFTU_D3
PF11819   DUF3338
PF08293   MRP-S33
PF00151   Lipase
Interpro
IPR004160   Transl_elong_EFTu/EF1A_C        + More
IPR009001   Transl_elong_EF1A/Init_IF2_C       
IPR004539   Transl_elong_EF1A_euk/arc       
IPR000795   TF_GTP-bd_dom       
IPR031157   G_TR_CS       
IPR027417   P-loop_NTPase       
IPR009000   Transl_B-barrel_sf       
IPR004161   EFTu-like_2       
IPR021774   DUF3338       
IPR009057   Homeobox-like_sf       
IPR001005   SANT/Myb       
IPR013219   Ribosomal_S27/S33_mit       
IPR013818   Lipase/vitellogenin       
IPR029058   AB_hydrolase       
SUPFAM
SSF50465   SSF50465        + More
SSF50447   SSF50447       
SSF52540   SSF52540       
SSF46689   SSF46689       
SSF53474   SSF53474       
Gene 3D
3.40.50.1820    
CDD
cd00167  SANT
ProteinModelPortal
H9JDB9   A0A2H1WDC6   A0A3S2TNN4   A0A2A4JZ61   A0A194RCQ3   A0A212EKY6   + More
W8BCW3   A0A1S3DCE5   A9XXA7   H9J271   A0A182MBB0   A0A0K8TZP3   A0A139WNV6   A0A0A1WJ43   A0A0A0QY84   A0A182V4W0   A0A182TV27   A0A182KR72   A0A182X3V3   Q7PT29   A0A182I369   P29520   A0A1Q3F505   A0A194PP74   A0A0K8TPH8   A0A0N1PF32   A0A1Q3F4X7   A0A0K8TN69   W5JEK7   T1PCL0   B0WQ61   I4DLT8   L7WID6   A0A0K2CTM2   A0A336KP24   A0A0M4EGZ9   A0A1A9XNA3   T1DMZ2   A0A2M3ZY17   A0A182FHI6   W5JJ91   A0A182F7Q8   A0A182GCR7   A0A3B0EBP7   A0A1B0BS76   A0A1Q3G3C8   A0A1J1IE44   A0A1A9ZUN3   A0A2A4JGU8   A0A1I8PVF8   B2DBL0   A0A1A9WF65   J9HYQ9   A0A182GHS1   A0A1A9W6Y1   A0A1A9V2G9   A0A182JBL5   A0A1A9ZYJ8   D3TNV8   Q1HR88   A0A0Q4U618   A0A182NSM3   A0A182QFB2   A0A1B0C5C9   A0A2U6X9K6   A0A0U4CK92   A0A069DZ22   A0A023FBG1   B4M0Y1   D6WKQ3   A0A0L7LTH3   A0A385AAY2   A0A291L1Q9   R4G8S8   A0A182MKN9   A0A182R8C4   A0A3B0K4V0   Q297R9   B4G2Y2   A0A182P0C0   A0A0B5L5V8   A0A1W4VVS6   B4QT88   E0D8P8   A0A385AAX8   B4IJ22   B3P515   A4V3Q6   B4PP14   P05303   A0A224XC81   E2J7D9   A0A182YLI8   B4JH67   A0A182VS18   A0A182UTJ1   A0A182WVW6   F5HL97   A0A182HZ72   B4N8S9  
PDB
5LZS     E-value=0,     Score=2042

Ontologies

KEGG
101743635    K03231 elongation factor 1-alpha | (RefSeq) elongation factor 1-alpha 2
PATHWAY
03013    RNA transport - Bombyx mori (domestic silkworm)
GO
GO:0005525   GO:0003746   GO:0003924   GO:0006412   GO:0006414   GO:0005737   GO:0003677   GO:0005576   GO:0016021   GO:0005853   GO:0010181   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

Topology

Subcellular location
Cytoplasm  
Secreted  
Length:
462
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.12213
Exp number, first 60 AAs:
0.0218
Total prob of N-in:
0.02455
outside
1  -  462
 
 

Population Genetic Test Statistics

Pi
178.507155
Theta
189.207406
Tajima's D
-0.537749
CLR
1.922716
CSRT
0.231888405579721
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28556443 EVSSYIK 96.88 1e-17
28556443 EHALLAFTLGVK 96.88 1e-17
25044914 IGYNPAAVAFVPISGWHGDNMIEPSTK 96.30 2e-13
26280517 MMETGMNVAR 96.55 1e-12
25044914 NMITEAAIDTETR 96.55 1e-12
27102218 RGYVAGDSK 96.55 1e-12
31223520 VETGVLKPGTIVVFAPANITTEVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 STTTGHLIYK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 SVEMHHEALQEAVPGDNVGFNVK 95.65 1e-09
28556443 STTTGHLIYK 95.65 1e-09
28556443 SGDAAIVNLVPSKPLCVESFQEFPPLGR 95.65 1e-09
25044914 VETFYDIQINIK 95.83 2e-08
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PGTIVVFAPANITTEVK 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 PLCVESFQEFPPLGR 100.00 1e-05
28556443 MDSTEPPYSEPR 100.00 1e-05
28556443 PGTIVVFAPANITTEVK 100.00 1e-05
26822097 EVSSYIK 100.00 4e-05
26280517 YYIYEIIK 100.00 4e-05
27102218 FAEIKEK 100.00 4e-05
28467696 YYVTIIDAPGHR 100.00 4e-05
28556443 KIGYNPAAVAFVPISGWHGDNMLEPSTK 100.00 9e-05
28556443 KIGYNPAAVAFVPISGWHGDNMLEPSTK 100.00 9e-05
28556443 CVESFQEFPPLGR 100.00 5e-04
28556443 CVESFQEFPPLGR 100.00 5e-04
28556443 AVAFVPISGWHGDNMLEPSTK 100.00 5e-04
28556443 CVESFQEFPPLGR 100.00 5e-04
28556443 CLIEALDAILPPARPTDKPLR 100.00 5e-04
28556443 CLIEALDAILPPARPTDKPLR 100.00 5e-04
31223520 MDSTEPPYSEPR 100.00 0.003
26822097 QTVAVGVIK 100.00 0.003
26280517 RIDMFEIDSFMYK 100.00 0.003
25044914 THIIFIDAEIAYPTSTGIPIHINIVGSATAK 100.00 0.003
28467696 THIMITQGIQECK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 SVEMHHEALQEAVPGDNVGFNVK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 THINIVVIGHVDSGK 100.00 0.003
28556443 SVEMHHEALQEAVPGDNVGFNVK 100.00 0.003
28556443 SVEMHHEALQEAVPGDNVGFNVK 100.00 0.003
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