Silkworm Genome Informatics Database

Gene

KWMTBOMO09085

Pre Gene Modal

BGIBMGA007577

Annotation

PREDICTED:_serine/threonine-protein_kinase_PAK_3_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr15(-):11044340-11054338 View in EpiBrowser

Full name

Non-specific serine/threonine protein kinase

Location in the cell

Nuclear Reliability : 2.924

CDS

ATGTCGAGTGACGAAGATAAACCGCCTGCACCACCGGTGCGTCTAACAAGTAATCGTGCCACTGATAGAGTAGACTCTGTAGCTTCAGTCGACATGAGACCTCTTCCGAAAGAGCCTGATGATGGTAGTGATAGGAAAAAGAAAACACTAAAAGCAAAAATAAAAGGATCAAAGAGTACAGCACACAATGATAATAAACCAAATATTAGTTATCCAACAAACTTTGAACACACCGTTCATGTTGGTTTTGATGCTGTTACGGGGGAATTCACTGGTATGCCAGAGGCATGGGCGCGACTTCTGATGGCTGCAAACATTAGTAAACAAGAACAGAAGAACAATCCACAGGCCGTATTAGATGTACTGAAATGGTATGATGCGTCTGCAACTCAACCTCCTCCTTCGAAGTATATGACTTCAGCTCAGATGCACACTACGCATTCAGAAGATACGGGAATGCGACCCCGGCCTTCTCGAGCTACTGCTACTACTTCCTCAACATCAGTCTGTAGTAGTAGTTCCTCAGTATCAAGAGTGTCATCGAGTAGTCCATCTTCATCTACACCTACCGACACAGAGCATCCAGAACCTCCCCCACCACCACCGTCACGACCAGACCGCACTAAAAGTATTTACACAAAGCCAATAGAGGAAGAAGAAGTTCCACCACCGCGACCGGCTCCGGCGCCAGCGGCTGTGACTACTCCCTCGTCACCACCGCCACATATACCGCATTCTGCCGTGACCACGCACTCTGTATGTCGCGCGGAAGGCGGCGTCGTGTCATTAGATCGAAATAAAAATCTACCGGCCGGCGTACCCGTGGCGCCACCACCCGCGCAGACCAACACCGAGACTGGACGAGCGACAGGACAGCAGCAAAGGAAAAAGAAAATGACTGATGAAGAAATCTTAGAAAAATTAAGAACAATTGTTAGCGTCGGCGATCCTAACAGAAAATACACCAAAATGGAAAAAATTGGTCAAGGAGCATCAGGCACGGTTTATACAGCGATAGAAACATCTACGGGAATGGAAGTGGCCATAAAACAGATGAATCTGAGTCAACAACCAAAGAAGGAACTCATCATAAACGAGATCCTTGTGATGCGGGAGAATAAACACAACAATGTTGTCAATTATCTCGACAGCTACCTTGTCAATGAGGAGTTATGGGTTGTAATGGAGTATTTAGCAGGTGGTTCACTGACCGACGTGGTGACCGAGACGTGCATGGACGAAGGTCAGATAGCCGCCGTCTGTCGAGAAGTACTACAGGCGTTACACTTTCTTCACACCAACCACGTCATACACAGAGATATTAAGTCTGATAACATATTGTTGGGTCTCGATGGACAAGTCAAGCTCACTGATTTTGGTTTCTGTGCTCAAATATCGCCCGAACAAAATAAACGAACGACAATGGTTGGTACGCCGTACTGGATGGCGCCTGAAGTCGTGACGAGAAAGCAATATGGACCTAAGGTAGATGTATGGTCATTGGGCATAATGGCAATCGAAATGATTGAAGGTGAACCACCTTACTTGAATGAGAATCCACTACGAGCATTGTATCTTATAGCCACAAATGGTAAACCCGATATTAAAGACAAAGATAAACTTAGTACAGTATTTCAAGACTTTTTGGATCAGTGCCTGGAGGTAGACGTCGAAAGGCGAGCTACTGCCTTAGATTTACTGAAGCATCCATTTTTGAAAATGGCTCGCCCTCTAGCTTCTTTAACACCTCTGATAATGGCAGCAAAAGAAGCAGCTAAGGGACATTAA

Protein

MSSDEDKPPAPPVRLTSNRATDRVDSVASVDMRPLPKEPDDGSDRKKKTLKAKIKGSKSTAHNDNKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMAANISKQEQKNNPQAVLDVLKWYDASATQPPPSKYMTSAQMHTTHSEDTGMRPRPSRATATTSSTSVCSSSSSVSRVSSSSPSSSTPTDTEHPEPPPPPPSRPDRTKSIYTKPIEEEEVPPPRPAPAPAAVTTPSSPPPHIPHSAVTTHSVCRAEGGVVSLDRNKNLPAGVPVAPPPAQTNTETGRATGQQQRKKKMTDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIETSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHNNVVNYLDSYLVNEELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREVLQALHFLHTNHVIHRDIKSDNILLGLDGQVKLTDFGFCAQISPEQNKRTTMVGTPYWMAPEVVTRKQYGPKVDVWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGKPDIKDKDKLSTVFQDFLDQCLEVDVERRATALDLLKHPFLKMARPLASLTPLIMAAKEAAKGH

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Uniprot

A0A194R784 A0A194PK95 A0A2A4JYJ7 A0A3S2P2Y0 A0A212EL17 A0A2H1WB73 + More

EC Number

2.7.11.1

Pubmed

26354079 22118469

EMBL

KQ460615 KPJ13683.1 KQ459602 KPI93433.1 NWSH01000353 PCG77097.1 + More
RSAL01000040 RVE50994.1 AGBW02014166 OWR42158.1 ODYU01007507 SOQ50335.1

Proteomes

UP000053240 UP000053268 UP000218220 UP000283053 UP000007151

Pfam

PF00069 Pkinase + More
PF00786 PBD

Interpro

IPR000095   CRIB_dom        + More
IPR000719   Prot_kinase_dom
IPR036936   CRIB_dom_sf
IPR033923   PAK_BD
IPR011009   Kinase-like_dom_sf
IPR008271   Ser/Thr_kinase_AS
IPR017441   Protein_kinase_ATP_BS

SUPFAM

SSF56112 SSF56112

Gene 3D

3.90.810.10

CDD

cd01093 CRIB_PAK_like

ProteinModelPortal

A0A194R784 A0A194PK95 A0A2A4JYJ7 A0A3S2P2Y0 A0A212EL17 A0A2H1WB73 + More

PDB

6FD3 E-value=2.82565e-144, Score=1314

KEGG

101743777 K04409 p21-activated kinase 1 [EC:2.7.11.1] | (RefSeq) serine/threonine-protein kinase PAK 3

PATHWAY

04392 Hippo signaling pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0005524 GO:0004674 GO:0004672 GO:0006468 GO:0016579 GO:0010181 GO:0006811 GO:0016020 GO:0016876 GO:0043039

Length:

595

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00303

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00047

outside

1 - 595

Pi

222.251247

Theta

193.587183

Tajima's D

0.410282

CLR

0.329331

CSRT

0.489675516224189

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics