Gene

KWMTBOMO09067  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007507

Annotation

PREDICTED:_probable_ubiquitin_carboxyl-terminal_hydrolase_FAF-X_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr15(+):10758575-10792986      View in EpiBrowser

Full name

Probable ubiquitin carboxyl-terminal hydrolase FAF      

Alternative Name

Protein fat facets
Ubiquitin thioesterase FAF
Ubiquitin-specific-processing protease FAF

Location in the cell

Cytoplasmic   Reliability : 1.61 Nuclear   Reliability : 1.907

CDS

ATGACACAGTCTCGTAACGACCAACCTTCATCATTAGAACAGTCTACAACTGAAACAAGAGTCACAGAGGTCTGGCATTTATTACGCCCTCTTGGTGTCTGTCATGATCTTCTCACTGCACATACTGTTACAACATACTTATTACCTGTGCTTGAATGCATACCAACGTTGTTAGAAAGTTTATCCGACGAAGAATTGAAGAAGGAAGCGCGAGGTAGTGAAAATAAGACTGATACCGTTTCCTGTTTGATTAGGGCTTGTAAATATGTTTCTGCAAAAACACCACAACATCATAGTCTTCTTAAGTCTCTTGAAATGTTTCGATTGAAAATGATATTGAGGTTATTACAAATGTCCTCATTTAATGGCAAAATGTCAGCACTGAATGAAATTAATCAACTTATAAGTACTTTTTCACAACAACCAAAACCAGAGTGGCTCACACCTGCTGTCATAACGAATTGGATTCGTGAGAACAAAGTAGTGGACATTGTGCTTCGTGATTCACTTCATCAACCTCAATATGTGGACAGATTAGAGAAAATGCTAAGGTTTATGATCAAAGAAAATTCGTTAACCACAGAAGACTTGGACGCTATTTGGAAGGCGCAGCACGGGAAACATGAAGCTATCGTGAAAAACCTGCACGATTTACTGTCGAAGTTAGCGTGGGATTTTACCCCTGACCAATTAGACCATCTTTTCGACTGTTTTAAGGCTAGTTGGGCTTCATCAAGTAAAAAACAAAGTGACAAATTGTTAGAGGTAATAAGAAGGCTTGCTGAAGATGATAAAGATGGAGTAATGGCGAACAAGGTTTTAGTACTTTTTTGGAACTTGGCACACTCCGATGAGGTATGCACAGAAATAATTGACGTGGCCCTTGCTAATCTAATCAAAATACTCGACTACAGTTGTAGTCAAGATCGCGATGCACAGAAAACTCTGTGGCTAAATAAGTGCGTAGAAGAGTTAAAAACAAACGAAAAATGGGTGCTTCCTGCGCTTAAGATGATGAAAGAAATCTGTTGTTTATACGAAGCGGGCGGAGGTACGGGCGTGCGACCTAATCTTACGAGACAGGAACTGATCGACCGGCTACAAACACAGCACTCCCTTGTCATATTGGTTACAAACTCTCTTACAAGTTATATGGATGGAGTTCGTAATAAACTTGCAGTTGATGGTGTTATCGATTGGGAGAATTGGTTACCCGATGGAAGATATCCACACGCAGCTCAGGTTCATGAACGACTTAGTTTTTTGCGGTTCTTATTGAAAGATGGTCAATTGTGGCTTTGTGCTGAACAGGCAAAACAGATTTGGGTATGTTTAGCGGAAAGGCCAGCGCACCTTGGAGACCGTGAAGCCTGTTTTCGATGGTTCAGTAAACTCATGGGAGAGGAACCTGATTTGGATCCAAATATCAACTTGCATTTTTTTCGACGTAACATTATGACTTTACCGCCTAATTTATTAACCCATGCCGGTATTAAATGTTTTGAGAGGTTTTTTAAAGCTGTGAATGCCAAAGAAGGTAAACTTAGGATTAAACGTAGAAGTTTTCAACTCAACGACGCTGATCTCATAGGAATAGATTATTTATGGAGAGTGATAACGGAATGCGACGACGACATATCGGCGCGCGGCATAGAGCTGTTGCGGGAAGTGTGCACGTGCGTGGGGCCGCAGCTGTCGCCGGCGATGCACCACGAGTCATTCCTAACGCAGTGCTGCGCACGAACGCAACGGCTCCAACGGGAAATGGAACAGCAAGAAGATAATCCCGAAGTTTGTACAAAAATGTGTAGAATAATTCGTGCCATACAAGAATACATTAATGAATGTGACAGAAGGTTTTCGTCGGAGCGACAAATACTGCCTATCTACAGAGCCGGTCGCGGAAGACAATGTACAATAATAGTAAGATTTAACTTTCAAACTGGCCAAAGACAAATTGAAGATATAGAATTATTTTCGCATTCTAACGAAACATTGCATTCTTTACGAGCATCGATCCAAAGAAGATTAAAATGTGCCTCGGATAGTACCATTAAATTAGAACTATATGTTAACAAATTAGAATTGTTTGTAAATGGTGAACTGTTGGATTCTAGTCACGATAAGAAAATACTTTCACAGATACCTCTCCGTGATAAAACTTTGATCGTCGCTAAGGTTTATGATGGACAAGTGTGTGGTAGCGGCGGATGCGGTTCCTCGAATGAATCCAGTAGTGATTCTAGCACATCTTCGCCGCCACTTTCACCTACTCCTGAAAACGCTTTACCTGGAGTTCTGTTTGCGCAAGGCTCGTGGTACTTACCATTTATATTAGAATTGGAACATGTTGGCATTACGAAGTTGCATGGACCATTGACTGAAGCGGCACATCTGCTATCACAAATTTGTCCTGCACATAAACTAACAATGGAGAAATTAACAGAAGCATTGTTATGTAGGGACGACACGAAACTCAGAGATATGCTTTATGGACCATCACCACCGACTGTAGCTTACAATATAGAGGTATTGTACAGCATGGTGATGCCGTCGTCAGACACGAGACTAGAACGCAGCCGGAATTACCAGCTGGCCTGTGTAAAGAAGGCTCCGCTACTGGTAAAATGCCTTTCTGACAAGGATTTTTTAAAAGATGCTGCTCCCCACACCAGAAGGGTAGGTTATTTAGCCTTAGTGAGACTGGCGAAGTTAATTTTGTACACCTTGGGATATTTATTTGAAATATTGGCGCCAGATGGATCTGATGTTTCGGTGGACAAAGATTTTAGAATGGATCTTACTATTTTAAGGGAGGCTCTCACCACTATACCAAATCACAGTTGTGAAATGATCGTGAAAGCAGTAGCGGAAAAGTTAGCGAATTCATTAGGAGAACAGGTTGTGATCGCCGGAGAAGAGAGTGACTCCGTATCGTCACTAGTGTGGTGGCGCGTCCCTACGATGGCGACGGTCCGGGCATTGTTTGCACTCGGATACTCTGTGGCGCAGCCTGTCGAGATGACTAGCATTGTACACCCCGACGACGTTACCTTGGTCCGAGAATGTATGGAAGTGGTGACTATATGCATGGCGCTTGGCGGCGGAAGACTGGATATGTTGCTTAACGAACCTTGGTGGCAGGATACCGCTCTTTACTTAATGATCGATTGCCCAAATCCACAAGTGCGCGTGTCGTGCGCGGAGCAGCTGCTGGCGATGTGTGCGTGGGGCGGCGGGGGCGGGGCGCGCAGCGTGCTGGCGGCGCTGGCCGGCACCGCGCTGCGCCTGCACCGGCACGCCGCGCACGCTATGCAGTTTCTGCAACTTCTCTGCCGTCTCGTCGCGCTCGCTGGACCCACCGATCGTACACTCGAAGACCTCGCGCTCGAGGTGGATTGGCTTCGAACCGCGAAAACTAACCCCGACACCTTGGACGACACTCTTCTCGAAGGACACCTTAATTTGACGAAAGAATTATTTGCTCATGTCCCGGCACAGGTCAAATACCAATATGGAGCTCATCCGGACCATAAAGACTCTGGACTTATTAAAGAAATAACGACGGAATTTTTGTGGCCGTACTCATGGGCTTGGCACGTGAATGGCAGCGGGAATGGTGGTGGCGGTGTAGGCGGGAGCGCGTCGGACTGCAGGCGCGAGCCGCCGGCGCCGCTGTGTCGCACGCCGGGGGCCGCCGCCGCCGCCGCCGACCTGCTGCTTGCGCTCGTACACGGCTGCGTTCTCAACATGGCCGCGCTTGCACGACTGTTAGAACAAATGTTCTATAGTGACAAGACAATGCCATTAGCTGAATGGGAATACATGCCTTGCGTGGGCCCACGGCCGCCTGCTGGACTTGTGGGGTTAAAAAATGCTGGAGCGACGTGTTACATGAATTCTGTGCTGCAGCAGCTATACTGTGTCCGAGCTGTCAGAGATACCATACTCACTGTGCAAGGAGCAGCAACAGATCCCAACGAAGATTTTTCTGGAGAAAGTCACCATCACAGTATTTTAGAAAATAATATAGAGAATAATACTGACTATAACATCACAATATTGAAACAAGTACAGGCGATATTTGCACATTTACATTGCAGCAAACTGCAATACTATGTTCCAAGAGGATTATGGGCCCATTTTAGGTTACAGGGCGAACCGGTAAACTTGCGTGAACAGCAGGATGCAGTTGAATTTTTCATGTCGTTGGTCGAGTCGTTAGATGAAGCTCTGAAGTCTTTGGGACAGGATCAATTGATGGCAAAAACGATGGGAGGAACTTACTCTGATCAAAAGATCTGCAAAGGCTGTCCGCATAGATACTGTAAGGAAGAGCCGTTCAGTGTTGTGTCTTTAGATATTAGAAATATGTCACGTCTCCAAGAATCATTAGAAGCTTATGTCCGTGGTGAACTGTTAGAAGGTGCTGATGCTTATCACTGTGATAAATGCAATAAAAAGGTGGTGACAGTGAAAAGGTTATGTCTGAACAAACTGCCCCCAGTATTAGTTATACAATTGAAAAGATTTGAATATGATTTCGAAAAAGTGTGTGCAATAAAATTCAATGACTATTTTGAATTCCCGAGAGACTTGGACGTCGAACCTTATACAGCGTGGGGCCTAGCACGAGCGGAAGGTGACTCGACTCTATGGGAGGGGGGCGAGGAGCGGACGCCTGAAACAAATTATCAACTCAGCGGGATCGTTGTACACTCCGGCCAGGCTTCCGGTGGGCACTATTATTCATACGTGCTCTTAAGGGATAACGGAAGCGAAACTGGCCGTTGGGTAAAATTAGACGATGGCGATGTATCGGAGTGTGCAATGCACGATGATGAAGAAATGAAGGCGCAATGCTTTGGTGGTGAATATATGGGAGAGGTTTACGATCCAATGTTGAAAAGGATTTCATATAAACGACAAAAACGATGGTGGAATGCCTACATGCTATTTTATACCAGGAAGGATACTATAGAAACAGTCGGTCTCGAGCAATCAATGCGTAATCTAACACTCAAGGAAAGTGCCATACCTCAGCCGATTTGGATGTCAGTACGTCGAAGCAATATTGCATTCTCCCATAATCAAGATCAATTTAGTCTCGAACATTTCAATTTTATGAAAAAATTGTGTTGTATGAGATTACAACTGACACATGGTTGTGTACAACAAAGTACTGTTTGGGGGCCTGAACAAGAGGAAATGTCAATGCTAGCGGTACAATTGGCAACTCGGTTTTTATTCCAAGTGGGATTTCGAACAAAGAAAACATTGCGAGGACCTGCGGCTGACTGGCACGAAATTCTATGTCAACATCTGAGGTGTTCATCGGCGATTAGAGCGTGGTTCGGGACTGAAATATTTAGATATCCACATAGAATATGTGATTATTTGTTATCATGCCCTACAGCGGAAATCAGAATAGTTTTTATGAAGATTATAGTTTTCCTAGCACATTTTTCAATTGAAGATCCACCAGTGAGTAACGGCTACGGCTCGTGGTGCACGCGCGAGGAGGCGCTCTCTCTGTCGGACCAGCTCGTGTGCAGCGTGCGGGCGCTCACCGCCCCGCACCCCGATGCACACGGCTCGCGACACTTGCCGCTGCTTTATAACCTCTTCCTCACCTACGCCAACCTGGGACTCACGGAGAAACTACAACTACTCCGGTTAAAAATCTTGGACATCATTCTCTCGGCCTGTATAGATGATACATCGTCCGGAGGAAAATACCAGTATCCAGAATCTGCTAAAGTACACCAGGTGGTGTGCGCTCTGCTGCGGTGCTGCGACGTTAGCGGGCGGTGTCAGTCGGCGGCGGAGGGCGCGGCGCCGTTGCCCAACCCGTACGCCGAGCCGCCGCACGTGGCGCCCGCCGACCGACATGTCATGTCACCCCTCGTTGCCGACATACTCTACAACAGATCCGGGACGTACATGAAGAAACTGACAGAGGAGTGTTGCGGCTGCGAGGAAGGCATCCGTATACTACAGTTTCTGTGCTGGGAAAACGCGGGCTGGTCTCGGCTGGCTCTGTCCGAGCTGTTGTGGCAGATGGCGTACGCGTACTGCCACGAGCTGCGGCGCCACGCCGACGCGCTCACCGCGCTGCTGCTCATGGAGGACAGCTGGCAACAGCGACGCATACATAACGTTATCAAGGGTGTGTCTGAGGAGAGGCCGGGACTGCTGGAGACGGCGGCCCGCTCGCGCGGACACTACCAGAAGCGTGCGTACGCGTGCGTGAAGCTCGTGGTAGGCGTCATGTGCCGCACGCCGCTCGCAGTGCGCGCCGTGCACACGCAGGCCGACGCGCGGCGCCGCTGGAGGCAGCTGCTCGCCTGGCTGCAGGACGAACTCGATCGCAAGTACGGTCCAGGATACGGGTCATACGGCACGTGGTCTCCGCCAGGAACCTCAAATGAAACGTCCAGCGGATACTTCCTCGAACGCAGTAACTCTGCGAGGAAAACTCTAGAAAAAGCATATCAGCTGTGTCCGGACGAAGATGAGGAAGAAGAAGAAGAAGGTCGGGAGGTTGCCGAAGGCTCCGGGTCGGGCGAGCCTGGCGAGGACAGCGGCGACGAGGACGAACCACCAGACGACGAGCCCCGACGTCTGCAGCCCCACGCGCTCTCCGGACTCGCAGCGTTTTCGGGAATAATGGAAAAGTATATAAGTGTTAAAGATTTAGAAGAAGCGGCCCTGAAACGTCTTCCAAAATCGGTGAGAGATTATTATAGCAGTGGTGCTACAGAAGAACAGACACTAGGAGAAAACAAAAACGCCTTTCAAAGGCTGCGAATAAGCCCCAAGTGCTTAGTGGGTGTAAATAATTGTGACCTTCGAACAACAGTGCTTGGAAATGAAATCTCAATGCCTATTGGTATATCTGCTACTGCGATGCAGCGCATGGCACACCCTGACGGAGAACTTGCTAATGTTAAAGCTGCTGCTAAGGAACAGACTATCTTTATGTTGAGCACCATCGCCACAACTTCTATAGAAGAAGTAGCAAACGCAGCGCCAGATGCTACTAAATGGTTTCAACTTTACATTTATAATGATAGAGAAGTAACAAAAAATTTAGTGCTGCGTGCAGAAAAACACGGATTTACAGCAATAGCGTTAACTGTAGACACGCCATTATTCGGCTTGCGACGCGCAGACATCCGGAATAAATTTACATTGCCCCGACACTTAAGATTAGCAAATTTCGATGGTATTTTATCTACAAAAATACACAATGCGAATAGTGGAAGTGGTTTAAATGAATACGTACAAGATCTACTTGACAAATCAGTAACTTGGAATGACATAAAGTGGTTGAAGAGTATCACAAGTCTCCCAATAATAGCGAAAGGTGTACTTCGTGGTGATGATGCTGTAAAAGCGGTAGAAGCTGGCTGTTCTGCTATTTTGGTATCTAATCACGGAGCAAGACAACTTGATGGAGTTCCAGCAACTATTGAAGCTTTGCCGGAAATTGTTGAAGCCCTAAAAGGTTACGACGTCGAAATATTTCTGGACGGCGGCGTTTCCACTGGCACTGATGTCTACAAGGCTTTGGCGCTTGGTGCAAAAATGGTTTTAGTGGGTCGTCCGGCACTGTGGGGTTTGACTGTAGGAGGGCAAGCCGGAGTGCAGAGGATGTTACAGATACTCCGTACGGAGCTTGAATATACGCTTCAGATTGCAGGAACCCCAACTGTCGCGGACGTCACGAAAGAAATGGTGAGGCATGAAAATTCGTATTGTAAACTTTGA

Protein

MTQSRNDQPSSLEQSTTETRVTEVWHLLRPLGVCHDLLTAHTVTTYLLPVLECIPTLLESLSDEELKKEARGSENKTDTVSCLIRACKYVSAKTPQHHSLLKSLEMFRLKMILRLLQMSSFNGKMSALNEINQLISTFSQQPKPEWLTPAVITNWIRENKVVDIVLRDSLHQPQYVDRLEKMLRFMIKENSLTTEDLDAIWKAQHGKHEAIVKNLHDLLSKLAWDFTPDQLDHLFDCFKASWASSSKKQSDKLLEVIRRLAEDDKDGVMANKVLVLFWNLAHSDEVCTEIIDVALANLIKILDYSCSQDRDAQKTLWLNKCVEELKTNEKWVLPALKMMKEICCLYEAGGGTGVRPNLTRQELIDRLQTQHSLVILVTNSLTSYMDGVRNKLAVDGVIDWENWLPDGRYPHAAQVHERLSFLRFLLKDGQLWLCAEQAKQIWVCLAERPAHLGDREACFRWFSKLMGEEPDLDPNINLHFFRRNIMTLPPNLLTHAGIKCFERFFKAVNAKEGKLRIKRRSFQLNDADLIGIDYLWRVITECDDDISARGIELLREVCTCVGPQLSPAMHHESFLTQCCARTQRLQREMEQQEDNPEVCTKMCRIIRAIQEYINECDRRFSSERQILPIYRAGRGRQCTIIVRFNFQTGQRQIEDIELFSHSNETLHSLRASIQRRLKCASDSTIKLELYVNKLELFVNGELLDSSHDKKILSQIPLRDKTLIVAKVYDGQVCGSGGCGSSNESSSDSSTSSPPLSPTPENALPGVLFAQGSWYLPFILELEHVGITKLHGPLTEAAHLLSQICPAHKLTMEKLTEALLCRDDTKLRDMLYGPSPPTVAYNIEVLYSMVMPSSDTRLERSRNYQLACVKKAPLLVKCLSDKDFLKDAAPHTRRVGYLALVRLAKLILYTLGYLFEILAPDGSDVSVDKDFRMDLTILREALTTIPNHSCEMIVKAVAEKLANSLGEQVVIAGEESDSVSSLVWWRVPTMATVRALFALGYSVAQPVEMTSIVHPDDVTLVRECMEVVTICMALGGGRLDMLLNEPWWQDTALYLMIDCPNPQVRVSCAEQLLAMCAWGGGGGARSVLAALAGTALRLHRHAAHAMQFLQLLCRLVALAGPTDRTLEDLALEVDWLRTAKTNPDTLDDTLLEGHLNLTKELFAHVPAQVKYQYGAHPDHKDSGLIKEITTEFLWPYSWAWHVNGSGNGGGGVGGSASDCRREPPAPLCRTPGAAAAAADLLLALVHGCVLNMAALARLLEQMFYSDKTMPLAEWEYMPCVGPRPPAGLVGLKNAGATCYMNSVLQQLYCVRAVRDTILTVQGAATDPNEDFSGESHHHSILENNIENNTDYNITILKQVQAIFAHLHCSKLQYYVPRGLWAHFRLQGEPVNLREQQDAVEFFMSLVESLDEALKSLGQDQLMAKTMGGTYSDQKICKGCPHRYCKEEPFSVVSLDIRNMSRLQESLEAYVRGELLEGADAYHCDKCNKKVVTVKRLCLNKLPPVLVIQLKRFEYDFEKVCAIKFNDYFEFPRDLDVEPYTAWGLARAEGDSTLWEGGEERTPETNYQLSGIVVHSGQASGGHYYSYVLLRDNGSETGRWVKLDDGDVSECAMHDDEEMKAQCFGGEYMGEVYDPMLKRISYKRQKRWWNAYMLFYTRKDTIETVGLEQSMRNLTLKESAIPQPIWMSVRRSNIAFSHNQDQFSLEHFNFMKKLCCMRLQLTHGCVQQSTVWGPEQEEMSMLAVQLATRFLFQVGFRTKKTLRGPAADWHEILCQHLRCSSAIRAWFGTEIFRYPHRICDYLLSCPTAEIRIVFMKIIVFLAHFSIEDPPVSNGYGSWCTREEALSLSDQLVCSVRALTAPHPDAHGSRHLPLLYNLFLTYANLGLTEKLQLLRLKILDIILSACIDDTSSGGKYQYPESAKVHQVVCALLRCCDVSGRCQSAAEGAAPLPNPYAEPPHVAPADRHVMSPLVADILYNRSGTYMKKLTEECCGCEEGIRILQFLCWENAGWSRLALSELLWQMAYAYCHELRRHADALTALLLMEDSWQQRRIHNVIKGVSEERPGLLETAARSRGHYQKRAYACVKLVVGVMCRTPLAVRAVHTQADARRRWRQLLAWLQDELDRKYGPGYGSYGTWSPPGTSNETSSGYFLERSNSARKTLEKAYQLCPDEDEEEEEEGREVAEGSGSGEPGEDSGDEDEPPDDEPRRLQPHALSGLAAFSGIMEKYISVKDLEEAALKRLPKSVRDYYSSGATEEQTLGENKNAFQRLRISPKCLVGVNNCDLRTTVLGNEISMPIGISATAMQRMAHPDGELANVKAAAKEQTIFMLSTIATTSIEEVANAAPDATKWFQLYIYNDREVTKNLVLRAEKHGFTAIALTVDTPLFGLRRADIRNKFTLPRHLRLANFDGILSTKIHNANSGSGLNEYVQDLLDKSVTWNDIKWLKSITSLPIIAKGVLRGDDAVKAVEAGCSAILVSNHGARQLDGVPATIEALPEIVEALKGYDVEIFLDGGVSTGTDVYKALALGAKMVLVGRPALWGLTVGGQAGVQRMLQILRTELEYTLQIAGTPTVADVTKEMVRHENSYCKL

Description

Ubiquitin C-terminal hydrolase involved in development and the imd/NF-kappa-B (IMD) signaling cascade (PubMed:23919485, PubMed:1295747). Required for eye and embryo development, and plays a role in compound eye assembly and oogenesis respectively (PubMed:1295747). In the larval eye disks, cells outside the assembling facets require this protein for short-range cell interactions that prevent the mystery cells from becoming photoreceptors (PubMed:1295747). Also required for nuclear migration and cellularization in early embryogenesis and could play a role in pole cell determination, development or function (PubMed:1295747). Regulates the IMD signaling cascade at later stages of infection (around 6 hours post-infection) by inhibiting the expression of the antimicrobial peptides Dpt and Dro (PubMed:23919485). Acts by modulating the state of imd polyubiquitination and/or stability; a function which appears to be independent of its enzymatic activity (PubMed:23919485). In turn, imd enhances the polyubiquitination and stability of faf suggesting that they may form a regulatory feedback mechanism within the Imd pathway (PubMed:23919485).

Catalytic Activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Cofactor

FMN

Subunit

Interacts with imd.

Similarity

Belongs to the peptidase C19 family.
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

Keywords

Alternative splicing   Complete proteome   Developmental protein   Differentiation   Hydrolase   Oogenesis   Phosphoprotein   Protease   Reference proteome   Sensory transduction   Thiol protease   Ubl conjugation   Ubl conjugation pathway   Vision  

Feature

chain  Probable ubiquitin carboxyl-terminal hydrolase FAF
splice variant  In isoform 3.

Uniprot

A0A2H1WVS5   A0A3S2TP78   A0A194R833   A0A195EYM8   A0A151WV29   F4W771   + More
A0A195BJS5   A0A158NJ55   A0A151JRZ4   E2A416   A0A3L8DR29   A0A195C536   E2BJY6   A0A0L7QM89   A0A067RUD8   A0A139WI67   D6WKR1   A0A026WEI3   K7IRB1   A0A088A5Z8   A0A154P3H2   A0A2A3EAM0   A0A310SNR3   A0A1Y1LX88   A0A1B6EYR0   A0A069DY94   A0A224XFS3   A0A146KRP5   A0A146LHV0   T1IZS4   A0A1W4VZZ5   A0A1W4VZD0   A0A1W4VM46   A0A1W4W000   B4K9J1   B3P500   A0A2R5LEU6   B4PP28   A0A1I8MTQ8   T1PH99   A0A1I8MTP3   A0A2S2Q1F3   A0A0P5D010   A0A0P5QCM4   A0A0P5FRF0   A0A2H8TU30   A0A0P4WMU4   A0A0P5IX11   A0A0P6FHD5   A0A0P5PY20   A0A0P5CYN1   A0A0M4EGW4   A0A0P6DG39   A0A0P5CPM7   A0A0P5C6C5   A0A0P4ZTV5   A0A0P6DRA5   A0A0P4WJ07   A0A0P6FYQ0   F7DP21   A0A0P5J8Q0   A0A0N8BIF8   A0A0N8D4I4   A0A0P5LIV4   A0A0P6ESZ5   A0A091KSE1   A0A0P5NZB1   H2M4X8   A0A3N0Y7K3   A0A091IBF3   K7FJZ4   K7FK11   A0A3P9MBV5   A0A3P9I9H7   A0A0B4K7S0   P55824   A0A0P6GU97   A0A3P8V0J2   J9K5U3   A0A0B4K6W2   P55824-3   A0A3P8V4M2   A0A3P8V203   A0A1W4XZT4   A0A1W4Y9A9   E9GZ89   A0A3B5JXV4   A0A0P5M757   Q4FE55   W5M2K6   A0A1W4Y9D5   A0A146MIG9   M4AUH4   A0A1W4XZ97   A0A315W606  

EC Number

3.4.19.12

Pubmed

26354079    21719571    21347285    20798317    30249741    24845553    + More
18362917    19820115    24508170    20075255    28004739    26334808    26823975    17994087    17550304    25315136    18464734    17554307    17381049    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    1295747    10731138    18327897    23919485    24487278    21292972    21551351    23594743    23542700    29703783   

EMBL

ODYU01011426    SOQ57158.1    RSAL01000033    RVE51433.1    KQ460615    KPJ13664.1    + More
KQ981920    KYN33012.1    KQ982708    KYQ51790.1    GL887813    EGI69955.1    KQ976453    KYM85441.1    ADTU01017494    KQ978579    KYN30005.1    GL436519    EFN71868.1    QOIP01000005    RLU22895.1    KQ978317    KYM95273.1    GL448708    EFN83995.1    KQ414894    KOC59763.1    KK852413    KDR24425.1    KQ971342    KYB27698.1    EFA03030.2    KK107293    EZA53439.1    KQ434809    KZC06489.1    KZ288305    PBC28777.1    KQ760706    OAD59322.1    GEZM01044529    GEZM01044528    JAV78164.1    GECZ01026966    JAS42803.1    GBGD01000019    JAC88870.1    GFTR01008974    JAW07452.1    GDHC01020989    JAP97639.1    GDHC01011704    JAQ06925.1    JH431723    CH933806    EDW16651.2    CH954182    EDV52914.1    GGLE01003915    MBY08041.1    CM000160    EDW99264.2    KA648202    AFP62831.1    GGMS01002404    MBY71607.1    GDIP01179159    JAJ44243.1    GDIQ01122608    JAL29118.1    GDIP01167409    GDIQ01253121    GDIQ01253120    GDIQ01253119    GDIP01085972    GDIP01069576    JAJ55993.1    JAJ98605.1    GFXV01005645    MBW17450.1    GDIP01254653    JAI68748.1    GDIQ01267984    GDIQ01225525    GDIQ01209235    GDIQ01209234    GDIQ01209233    GDIQ01207931    GDIQ01207930    GDIQ01207929    GDIQ01206629    GDIQ01205182    GDIQ01205181    GDIQ01205180    GDIQ01201581    GDIQ01201580    GDIQ01201579    GDIQ01200380    GDIQ01189033    GDIQ01181138    GDIQ01159547    GDIQ01147757    GDIQ01147756    GDIQ01147755    GDIQ01146352    GDIQ01145154    GDIQ01145153    GDIQ01097973    GDIQ01096317    GDIQ01079877    GDIQ01067183    GDIQ01058336    JAK43795.1    GDIQ01047791    GDIQ01047790    JAN46947.1    GDIQ01122609    JAL29117.1    GDIP01165159    JAJ58243.1    CP012526    ALC45446.1    GDIQ01077877    JAN16860.1    GDIP01168560    JAJ54842.1    GDIP01179158    JAJ44244.1    GDIP01208807    JAJ14595.1    GDIQ01077878    JAN16859.1    GDIP01254654    JAI68747.1    GDIQ01043643    JAN51094.1    GDIQ01203479    GDIQ01203478    JAK48246.1    GDIQ01174595    JAK77130.1    GDIP01069575    JAM34140.1    GDIQ01170342    JAK81383.1    GDIQ01058337    JAN36400.1    KK753039    KFP42418.1    GDIQ01140156    JAL11570.1    RJVU01050883    ROL42001.1    KL218485    KFP05899.1    AGCU01157784    AGCU01157785    AGCU01157786    AGCU01157787    AGCU01157788    AGCU01157789    AGCU01157790    AGCU01157791    AGCU01157792    AGCU01157793    AE014297    AFH06704.1    AFH06707.1    AHN57626.1    L04959    L04958    L04960    AF145677    GDIQ01029298    JAN65439.1    ABLF02019680    ABLF02019682    ABLF02019684    AFH06705.1    AFH06706.2    GL732577    EFX75197.1    GDIQ01171638    JAK80087.1    BX545856    DQ086492    AAY99448.1    AHAT01025064    GCES01166831    JAQ19491.1    NHOQ01000293    PWA31177.1   

Proteomes

UP000283053    UP000053240    UP000078541    UP000075809    UP000007755    UP000078540    + More
UP000005205    UP000078492    UP000000311    UP000279307    UP000078542    UP000008237    UP000053825    UP000027135    UP000007266    UP000053097    UP000002358    UP000005203    UP000076502    UP000242457    UP000192221    UP000009192    UP000008711    UP000002282    UP000095301    UP000092553    UP000002279    UP000001038    UP000054308    UP000007267    UP000265180    UP000265200    UP000000803    UP000265120    UP000007819    UP000192224    UP000000305    UP000005226    UP000000437    UP000018468    UP000002852   

PRIDE

P55824   

Pfam

PF00443   UCH        + More
PF01070   FMN_dh

Interpro

IPR028889   USP_dom        + More
IPR016024   ARM-type_fold       
IPR018200   USP_CS       
IPR038765   Papain-like_cys_pep_sf       
IPR001394   Peptidase_C19_UCH       
IPR000262   FMN-dep_DH       
IPR013785   Aldolase_TIM       
IPR037396   FMN_HAD       

SUPFAM

SSF48371   SSF48371        + More
SSF54001   SSF54001       

Gene 3D

3.20.20.70    

ProteinModelPortal

A0A2H1WVS5   A0A3S2TP78   A0A194R833   A0A195EYM8   A0A151WV29   F4W771   + More
A0A195BJS5   A0A158NJ55   A0A151JRZ4   E2A416   A0A3L8DR29   A0A195C536   E2BJY6   A0A0L7QM89   A0A067RUD8   A0A139WI67   D6WKR1   A0A026WEI3   K7IRB1   A0A088A5Z8   A0A154P3H2   A0A2A3EAM0   A0A310SNR3   A0A1Y1LX88   A0A1B6EYR0   A0A069DY94   A0A224XFS3   A0A146KRP5   A0A146LHV0   T1IZS4   A0A1W4VZZ5   A0A1W4VZD0   A0A1W4VM46   A0A1W4W000   B4K9J1   B3P500   A0A2R5LEU6   B4PP28   A0A1I8MTQ8   T1PH99   A0A1I8MTP3   A0A2S2Q1F3   A0A0P5D010   A0A0P5QCM4   A0A0P5FRF0   A0A2H8TU30   A0A0P4WMU4   A0A0P5IX11   A0A0P6FHD5   A0A0P5PY20   A0A0P5CYN1   A0A0M4EGW4   A0A0P6DG39   A0A0P5CPM7   A0A0P5C6C5   A0A0P4ZTV5   A0A0P6DRA5   A0A0P4WJ07   A0A0P6FYQ0   F7DP21   A0A0P5J8Q0   A0A0N8BIF8   A0A0N8D4I4   A0A0P5LIV4   A0A0P6ESZ5   A0A091KSE1   A0A0P5NZB1   H2M4X8   A0A3N0Y7K3   A0A091IBF3   K7FJZ4   K7FK11   A0A3P9MBV5   A0A3P9I9H7   A0A0B4K7S0   P55824   A0A0P6GU97   A0A3P8V0J2   J9K5U3   A0A0B4K6W2   P55824-3   A0A3P8V4M2   A0A3P8V203   A0A1W4XZT4   A0A1W4Y9A9   E9GZ89   A0A3B5JXV4   A0A0P5M757   Q4FE55   W5M2K6   A0A1W4Y9D5   A0A146MIG9   M4AUH4   A0A1W4XZ97   A0A315W606  

PDB

5WCH     E-value=6.22467e-149,     Score=1360

KEGG

101738334    K11840 ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12] | (RefSeq) probable ubiquitin carbo

GO

GO:0006511   GO:0036459   GO:0016579   GO:0004197   GO:0004843   GO:0005737   GO:0016491   GO:0007349   GO:0009950   GO:0008583   GO:0035192   GO:0016787   GO:0048477   GO:0007601   GO:0006897   GO:0045861   GO:0050829   GO:0045824   GO:0008354   GO:0003824   GO:0005488   GO:0010181   GO:0006811   GO:0016020   GO:0016876   GO:0043039   GO:0055114  

Length:

2590

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.14719

Exp number, first 60 AAs:

0.0362

Total prob of N-in:

0.00178

outside

1  -  2590

 

 

Pi

245.776394

Theta

176.936052

Tajima's D

0.559375

CLR

0.801138

CSRT

0.531623418829059

Interpretation

Uncertain