Gene

KWMTBOMO09062

Pre Gene Modal

BGIBMGA007584

Annotation

PREDICTED:_gamma-tubulin_complex_component_3_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr15(-):10732566-10741804      View in EpiBrowser

Full name

Gamma-tubulin complex component       + More
Gamma-tubulin complex component 3 homolog      
Gamma-tubulin complex component 3      

Alternative Name

Gamma-ring complex protein 109
Xgrip109
Gamma-ring complex protein 104 kDa
Spindle pole body protein Spc98 homolog

Location in the cell

Mitochondrial   Reliability : 1.349 Nuclear   Reliability : 1.731

CDS

ATGGAACCGACTTCGACCAATGTCGCAGAACTTCTTCATAAATTATGTTCCCATCTGTCAACAGATCTAGATGGTGCATATGAACTGGCTATGTCATATTTGTCATCAACAAGCGAAAAGACGCGTTCATCTGCAGACGAGAAACTACTTTGTCAAAAGATTTACTCAAAGTTGTGTAGCAGATCCTCTCGAGATGCAGAAAAGTTCAATGAATATCATTCAAAATTAAGGAATTGTTTCATTCTAAAACAGCGTTTATCTGTTTTGAGCCTGTTGTTAGCCCTGTCAGAACTGCCGCAGCACTCTGATTCAACACTTCAGCTGTTTCCTATACCACAGTTAGCTAACGCTAAATCTGCAACTGGTATCCCGGCTGTTATACCTAGTATAAGCAAGAGTACTATTGGTTCAGTGAGCTGGACCAACTCACTAAAGCAACAAATTTCTGAGCAGAGCATACCTTCTAATAATAATATGGCACTGTCAATCCACCAAGCAGATCGTCCGAATGAGCGTAGTTGTGTGCGTGAAGCTGTGTTGGCGGCTACTGGAGTGAAATGTCGTAATTCAGGAGCTGGATCTCGACCGATGCAAGCCCTGTACTCTCGTATTGCTCACCTGGGTTTTCTGCATGATAGACTAAAAGAATTCATTGATCCATTGTCTGGCCTCATGCCGCAAGGTTTGATGGGTGAGGGGCTAGTAACCGCCATCAGAGATGAACTCACAGAGTACTACCGCAGTGTTGCACTTCTTCAATCACAGGCTTGTGAAGGTGACGGAGGAGGCGCCACCTTACGTCGCGTGTGTGTCTGGGCACAAGAACCTCTGCACCGTCTCACGTGGCTTGCTAATATGGCACATGCTGCACAACATAAAAAAGGTGGCGAGCTAGCGTCGTGCGTGCACCGCTTCGTCCGTCACGGCGACGAGCGCGTGTCGTCACTAGCGCGCCGCCTGCTCACTGCGCTCACCTACCCGCTGCTGCTCATGCTGACCCGCTGGCTCTTACACGGAGAAATCGATGACCCGTTCAATGAGTTCTTCATTGAAAGTCGAAGCGGTGTGCCTATTGATCGAATGTGGCATGACAAATACCGAGTCAGGGAATGGATGGTGCCGTCGTTCATGTGCCGCGAGCAGGCCGCGCAGATCCTGGCCACCGGGAAGAGCGTCGTGTTTATGCGCGAGGCGTGCGCCGACGAGCCAGACCACGCCCCCCACGCGCACCATCTACACTCCCTGCTCAAACCCGATACAGGATAA

Protein

MEPTSTNVAELLHKLCSHLSTDLDGAYELAMSYLSSTSEKTRSSADEKLLCQKIYSKLCSRSSRDAEKFNEYHSKLRNCFILKQRLSVLSLLLALSELPQHSDSTLQLFPIPQLANAKSATGIPAVIPSISKSTIGSVSWTNSLKQQISEQSIPSNNNMALSIHQADRPNERSCVREAVLAATGVKCRNSGAGSRPMQALYSRIAHLGFLHDRLKEFIDPLSGLMPQGLMGEGLVTAIRDELTEYYRSVALLQSQACEGDGGGATLRRVCVWAQEPLHRLTWLANMAHAAQHKKGGELASCVHRFVRHGDERVSSLARRLLTALTYPLLLMLTRWLLHGEIDDPFNEFFIESRSGVPIDRMWHDKYRVREWMVPSFMCREQAAQILATGKSVVFMREACADEPDHAPHAHHLHSLLKPDTG

Description

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Subunit

Interacts with gamma-tubulin.
Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. Interacts with CDK5RAP2; the interaction is leading to centrosomal localization of TUBGCP3 and CDK5RAP2. Interacts with NIN (via N-terminus); the interaction may promote recruitment of the gamma-tubulin ring complex to the centrosome (By similarity).

Similarity

Belongs to the TUBGCP family.

Keywords

Cytoplasm   Cytoskeleton   Direct protein sequencing   Microtubule   Acetylation   Alternative splicing   Complete proteome   Phosphoprotein   Polymorphism   Reference proteome  

Feature

chain  Gamma-tubulin complex component 3 homolog
splice variant  In isoform 3.
sequence variant  In dbSNP:rs1044287.

Uniprot

A0A2A4IYP9   A0A2H1WVS7   A0A212EP19   A0A3S2LPZ6   A0A194PJ08   S4P7T5   + More
A0A194RCM7   A0A1B0D8W7   A0A1W4XGV0   A0A182KBQ7   A0A182TWG8   A0A158NPS5   F4W7H2   A0A182UPC3   A0A067RBF3   E2BZ55   A0A182WUZ4   A0A195ATD3   Q7QFS6   A0A182LAH0   A0A182I8M0   A0A151JST0   A0A195EKZ8   A0A151X8N9   A0A182P2Q1   A0A182NG02   A0A151INW1   A0A2T7NAW8   D6WM36   E1ZZY6   A0A182XX59   A0A182W137   A0A182FSV4   A0A182RRT7   A0A026WIU5   O73787   A0A1L8H8V9   E9IX19   K7JAQ7   Q6PF23   A0A1L8HH01   B1H2U5   A0A3B3ITE3   A0A182M1W3   A0A3B0JC28   A0A3B0JDA5   A0A182QZ54   Q96CW5-2   A0A2Y9RNQ6   Q96CW5   B4DYP7   A0A091H1V6   A0A2Y9DYW0  

Pubmed

22118469    26354079    23622113    21347285    21719571    24845553    + More
20798317    12364791    14747013    17210077    20966253    18362917    19820115    25244985    24508170    30249741    9566968    27762356    21282665    20075255    20431018    15057823    19369195    19690332    21269460    22814378    23186163    25944712    9566967    9566969    14702039    15489334    14654843    17959831   

EMBL

NWSH01004559    PCG64945.1    ODYU01011426    SOQ57161.1    AGBW02013542    OWR43238.1    + More
RSAL01000033    RVE51436.1    KQ459602    KPI93406.1    GAIX01004454    JAA88106.1    KQ460615    KPJ13661.1    AJVK01004160    AJVK01004161    ADTU01022725    GL887844    EGI69845.1    KK852751    KDR17134.1    GL451563    EFN79024.1    KQ976745    KYM75451.1    AAAB01008844    EAA06014.4    APCN01003086    KQ982014    KYN30664.1    KQ978730    KYN28935.1    KQ982409    KYQ56699.1    KQ976914    KYN07125.1    PZQS01000014    PVD18317.1    KQ971343    EFA04217.1    GL435531    EFN73258.1    KK107182    QOIP01000011    EZA55945.1    RLU16685.1    AF052663    CM004469    OCT92539.1    GL766616    EFZ14883.1    AAZX01000978    AAZX01016257    BC057755    AAH57755.1    CM004468    OCT95373.1    AAMC01018036    AAMC01018037    AAMC01018038    AAMC01018039    BC161134    AAI61134.1    AL139384    AL160033    AXCM01001964    OUUW01000003    SPP78093.1    SPP78092.1    AXCN02000343    AF042378    AJ003061    AJ003062    BT009772    AK314785    CH471085    BC007763    BC013781    BC046634    AK302537    BAG63809.1    KL521580    KFO89816.1   

Proteomes

UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    UP000092462    + More
UP000192223    UP000075881    UP000075902    UP000005205    UP000007755    UP000075903    UP000027135    UP000008237    UP000076407    UP000078540    UP000007062    UP000075882    UP000075840    UP000078541    UP000078492    UP000075809    UP000075885    UP000075884    UP000078542    UP000245119    UP000007266    UP000000311    UP000076408    UP000075920    UP000069272    UP000075900    UP000053097    UP000279307    UP000186698    UP000002358    UP000008143    UP000005640    UP000075883    UP000268350    UP000075886    UP000248480   

PRIDE

O73787    Q96CW5    B4DYP7   

Pfam

PF17681   GCP_N_terminal        + More
PF04130   GCP_C_terminal

Interpro

IPR041470   GCP_N        + More
IPR007259   GCP       
IPR040457   GCP_C       
IPR042241   GCP_C_sf       

Gene 3D

1.20.120.1900    

ProteinModelPortal

A0A2A4IYP9   A0A2H1WVS7   A0A212EP19   A0A3S2LPZ6   A0A194PJ08   S4P7T5   + More
A0A194RCM7   A0A1B0D8W7   A0A1W4XGV0   A0A182KBQ7   A0A182TWG8   A0A158NPS5   F4W7H2   A0A182UPC3   A0A067RBF3   E2BZ55   A0A182WUZ4   A0A195ATD3   Q7QFS6   A0A182LAH0   A0A182I8M0   A0A151JST0   A0A195EKZ8   A0A151X8N9   A0A182P2Q1   A0A182NG02   A0A151INW1   A0A2T7NAW8   D6WM36   E1ZZY6   A0A182XX59   A0A182W137   A0A182FSV4   A0A182RRT7   A0A026WIU5   O73787   A0A1L8H8V9   E9IX19   K7JAQ7   Q6PF23   A0A1L8HH01   B1H2U5   A0A3B3ITE3   A0A182M1W3   A0A3B0JC28   A0A3B0JDA5   A0A182QZ54   Q96CW5-2   A0A2Y9RNQ6   Q96CW5   B4DYP7   A0A091H1V6   A0A2Y9DYW0  

PDB

5FM1     E-value=0.0787734,     Score=84

KEGG

101738472    K16570 gamma-tubulin complex component 3 | (RefSeq) gamma-tubulin complex component 3 homolog

GO

GO:0000922   GO:0043015   GO:0005737   GO:0005815   GO:0007020   GO:0005874   GO:0005813   GO:0051225   GO:0000278   GO:0000930   GO:0031122   GO:0000923   GO:0051415   GO:0051321   GO:0008275   GO:0016021   GO:0005814   GO:0005198   GO:0005829   GO:0005819   GO:0007338   GO:0005200   GO:0005827   GO:0016020   GO:0000226   GO:0005254   GO:0006811   GO:0016876   GO:0043039  

PANTHER

PTHR19302  

Subcellular location

  

Length:

421

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.19412

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01318

outside

1  -  421

 

 

Pi

328.982945

Theta

184.666492

Tajima's D

3.303094

CLR

0.651465

CSRT

0.990200489975501

Interpretation

Uncertain