Gene

KWMTBOMO09057  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007503

Annotation

PREDICTED:_extended_synaptotagmin-1_[Bombyx_mori]

Location

Bomo_Chr15(+):10667315-10692943      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.42 Nuclear   Reliability : 1.448

CDS

ATGGCCAGTGATAATAACATGGCAGGTGCAAGCAAAACTGCCTTACCACCAGGCAGTGATGATGGCAACAGTGTTTTTTCTATGATGTACACATTTCTCAAAAAGGTGTCGATTGTAGGAGCTGTGTACTTAGTAGGTTATATGCAATGGAGCGTTGCGTGGCTTATTGGGCCCGTTATATTGTCGGTGATGCGCGATCAATGGCGCAAGGAGAACGAATACAAACGCAACATCGCAAAGGTCGCTGCACTGTCTTCTGAAAAAGATGTGATACTAGCGAGACTTGACGACTTGCCTTCATGGGTATTCTTCCCGGACGTCGAACGAGCCGAATGGTTGAACAGGATACTCCTACAAGTCTGGCCGAATGTGAACAGCTACGCAAAGACTTTATTGAAAGACTTGATCGAACCGGCTGTCGCGGAGAGCCTGGCCAATTACAAACTCAGCGGATTTAAATTTGAACGTATGATTCTCGGTACCATTGCGCCGCGGGTTGGTGGCGTCAAGGTTTATGATAAGAATCTCTCGAGGAATGAAATCATCATGGACATAGACTTATTCTACGCCGGCGATTGCGACATCTCATTCGTACTTCAACGCATTCGCGGAGGAATCAAAGATCTCCAAATTCACGGCATGGTACGTGTTGTAATGAAACCTCTGATCTCTAAAATACCGTTAGTCGGAGGACTACAGATCTTCTTTTTGAACAACCCCTCAATCGACTTCAATCTCGTTGGCGCAGCTGACATACTAGATATGCCAGGCTTTAGTGATATACTTCGTCGATGCATCGTGGAGCAAGTGTCCAAAATGATGGTGCTGCCTAACAAGCTTTCGATCAAACTAAGCGATGAGATTCCAACGGTTGATCTGCGCATGCCTGAGCCGGAGGGTGTACTTCGCATACATTTGGTTCAAGCTCAGAATCTCATGAAGAAAGATGTTTCTATGCTAGGAAAAGGCAAGTCAGATCCGTATGCAGTTATAACTGTGGGCGCCCAGCAATGGAAAACGAAGCACATTGATAACAACGTGAACCCGCGATGGGACTTCTGGTGTGAGGCGCGTATAATGCAATCCCTCGGTCAGATGTTGGATATAGAGGTGTTCGACAAGGACGAAGGCAACGACGACGACAAGCTCGGCAAGTGTTCATTGGACATATCTCAAGTAGTTCGATTTGGCCGCTTGGACACTTGGCAGACCTTGCAACAAGCGAAGCACGGTAAAGTCCAACTGAGATTATCTTGGCATCGTTTATCCACGGATGTAACTGAGTTAAGTCGAGCACTGACGGAAACTCTCCTTATCAAGACGGGAGATTTGAGCTCAGCAGTACTCTCTGTTTACATAGACTCGTGTAAGAAGCTACCGAACGCCCGTGTGCAATCCCGTCCGGACCCTTACCTGATGGTGACGGTTGGCAAAAAAACCGAAAACACCGCCGTGCAACTGCGAACCGATGATCCCGTGTATGAGATCGGATATTCTTTCCTCGTCCAGAACCCTGAAATCGACACGCTTGACGTCAAAGTTCTCGACCAGAAAACTGGAAGCCAACTCGGTCAATTGTTCTATAGCATCTCCGCTTTGCTTAAAGAAAAAGATCTGACGATGCTGACTCAGCCGCTGATGTTGCAGAAATCTGGGCCCGAGTCCAAAATCATACTGTCCTTACAATTGAGGATTCTCAAAGAAGCCATAAAAGAGGTCGATATTGACGAAGAGAGTTTGGAAGCGGCGGTCGCGGAGCCGAGCCCCCCCACCCCGAGCCCCTCCGTGTCGTCGGCGGCCACCGACACCACGGACGGCGGCGCCTCGCACCCGCGCCCGCAGTCCGCCGCGCCCGCCGACTCGCTGCCTGCACAACCTGCTTCATCAGGTGATACTGAATTAAAGAATATTGAAGATTCTGTACAAGACGACGCCTCGCAGAGATCCGTGCCAGAGGAAATAATTGATAAAGAAGTCGATTCTCCTCAAGAGAACCAACCTCCATCTGGACGCGACTCTCCAAAACTCATCCACAGGACTTCGTCATTAACTACTTCCGCTGGGGAAGCCGGTCTGGGCCGCATATTACTCTCTCTGCGCTATAGTATGCAGAATCAAACATTATATATTGTTGTTCACAAGATAATGAATATCCCGCTGAAAGATCCTACAAATGTGCCCGATCCGTACGTTAAATTGTATCTACTGCCGGGTAGAACTAAAGATTCAAAACGCAAGACAGTGGTGGTAAAAGACAGCTGTATGCCGGAATATGACGAACAATTCGAATGGGTGATTCCATTAGCTGAGCTTCACTCCAGGCAAGTCGAAGTCACTGTTGCCACCCACAAGGGATTCCTGGCTGGCAGTCCGGTCATTGGACAGGTTGTAGTCCATCTAAATCAGTACGATTTCCGTGAAGCTAAAACCCTGTGGTTCGATCTTATGCCTGAAACATCCCCTAGAGATTAA

Protein

MASDNNMAGASKTALPPGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYKRNIAKVAALSSEKDVILARLDDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEIIMDIDLFYAGDCDISFVLQRIRGGIKDLQIHGMVRVVMKPLISKIPLVGGLQIFFLNNPSIDFNLVGAADILDMPGFSDILRRCIVEQVSKMMVLPNKLSIKLSDEIPTVDLRMPEPEGVLRIHLVQAQNLMKKDVSMLGKGKSDPYAVITVGAQQWKTKHIDNNVNPRWDFWCEARIMQSLGQMLDIEVFDKDEGNDDDKLGKCSLDISQVVRFGRLDTWQTLQQAKHGKVQLRLSWHRLSTDVTELSRALTETLLIKTGDLSSAVLSVYIDSCKKLPNARVQSRPDPYLMVTVGKKTENTAVQLRTDDPVYEIGYSFLVQNPEIDTLDVKVLDQKTGSQLGQLFYSISALLKEKDLTMLTQPLMLQKSGPESKIILSLQLRILKEAIKEVDIDEESLEAAVAEPSPPTPSPSVSSAATDTTDGGASHPRPQSAAPADSLPAQPASSGDTELKNIEDSVQDDASQRSVPEEIIDKEVDSPQENQPPSGRDSPKLIHRTSSLTTSAGEAGLGRILLSLRYSMQNQTLYIVVHKIMNIPLKDPTNVPDPYVKLYLLPGRTKDSKRKTVVVKDSCMPEYDEQFEWVIPLAELHSRQVEVTVATHKGFLAGSPVIGQVVVHLNQYDFREAKTLWFDLMPETSPRD

Uniprot

A0A1E1WHH0   A0A1E1WVZ1   A0A1E1WR37   A0A194PJ99   A0A212EP34   A0A1B0CUF4   + More
A0A1S4FLH5   Q16WM9   A0A023EW26   A0A182G462   A0A1Q3FZ48   A0A2M4BD42   A0A2M4BDD3   A0A182N5H2   A0A2M4BDK5   A0A2M4BDE8   A0A182QM74   A0A1L8DZX3   A0A084W4Z9   A0A182R5P9   A0A182J284   A0A2M3YYD3   A0A182FKR4   A0A2M4A0R3   A0A2M4A0N4   A0A182WVD1   A0A182LB03   A0A453Z2A5   Q5TVA9   A0A182UYE8   A0A0K8WH19   A0A1L8DZP3   T1P7K2   A0A1I8M6J8   A0A034VAE4   A0A034VBK8   A0A034VD48   W5JAG8   A0A1W4UT63   B3N1S0   B4QT78   W8B3N3   W8BVK5   A0A1B6M122   A0A1Q3FZ41   Q7KS16   Q9VC62   B4PVS6   A0A0A1WIF5   A0A0R1E5U4   A0A1W4V6I4   A9UNH8   A0A0P8ZJE0   A0A0A1X4F3   U5EHK3   A0A0P8XZD3   A0A1L8E098   A0A3B0KCB9   A0A3B0JQX0   Q293H6   A0A1B0GDH3   A0A0B4KGU9   A0A182JSB2   A0A1W4USS3   A0A0M5J2D6   A0A0P9BTA2   B4JG26   B4KB48   A0A0R1E5U3   A0A1W4V5I1   A0A0R3NKG2   A0A1I8Q3P6   A0A1J1IG23   A0A0B4K6F9   A0A1J1IJH6   A0A1J1IG34   B3P718   A0A0R1E5T7   A0A3B0JM38   A0A1Q3FZ65   A0A0Q9XB46   A0A3B0JM70   A0A3B0JM99   A0A0R1E5T6   A0A1Q3FZ30   A0A0R3NKF1   A0A1Q3FZ44   B4LYB1   E0VZ51   V5IAC8   A0A0Q9WEU1   A0A0Q9XAA2   A0A0Q9X0T2   D6WLV7   A0A336MS91   B4NIG9   A0A1I8Q3P9   A0A1I8Q3M4   A0A1I8Q3N9  

Pubmed

26354079    22118469    17510324    24945155    26483478    24438588    + More
20966253    12364791    14747013    17210077    25315136    25348373    20920257    23761445    17994087    24495485    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25830018    15632085    20566863    18362917    19820115   

EMBL

GDQN01004698    JAT86356.1    GDQN01000113    JAT90941.1    GDQN01001616    JAT89438.1    + More
KQ459602    KPI93402.1    AGBW02013542    OWR43243.1    AJWK01029142    CH477560    EAT38995.1    GAPW01000170    JAC13428.1    JXUM01042316    JXUM01042317    JXUM01042318    JXUM01042319    JXUM01042320    JXUM01042321    JXUM01042322    JXUM01042323    JXUM01042324    JXUM01042325    GFDL01002228    JAV32817.1    GGFJ01001825    MBW50966.1    GGFJ01001830    MBW50971.1    GGFJ01001942    MBW51083.1    GGFJ01001933    MBW51074.1    AXCN02001170    AXCN02001171    GFDF01002135    JAV11949.1    ATLV01020438    KE525302    KFB45293.1    GGFM01000523    MBW21274.1    GGFK01001014    MBW34335.1    GGFK01001022    MBW34343.1    AAAB01008844    EAL41323.4    EGK96340.1    GDHF01001932    JAI50382.1    GFDF01002134    JAV11950.1    KA644546    AFP59175.1    GAKP01019458    JAC39494.1    GAKP01019460    JAC39492.1    GAKP01019459    JAC39493.1    ADMH02002044    ETN59779.1    CH902661    EDV34039.2    CM000364    EDX14242.1    GAMC01013368    JAB93187.1    GAMC01013366    JAB93189.1    GEBQ01022259    GEBQ01010387    JAT17718.1    JAT29590.1    GFDL01002227    JAV32818.1    AE014297    BT133066    AAN14000.2    AEX93151.1    AAF56313.1    CM000160    EDW98925.1    GBXI01015503    JAC98788.1    KRK04557.1    BT031342    ABY21755.1    KPU74906.1    GBXI01008093    GBXI01006248    JAD06199.1    JAD08044.1    GANO01002984    JAB56887.1    KPU74907.1    GFDF01001990    JAV12094.1    OUUW01000007    SPP83356.1    SPP83353.1    CM000070    EAL29239.3    CCAG010011881    AGB96301.1    CP012526    ALC47074.1    KPU74905.1    CH916369    EDV93593.1    CH933806    EDW15752.2    KRK04555.1    KRT01417.1    CVRI01000049    CRK99215.1    AFH06605.1    CRK99214.1    CRK99213.1    CH954182    EDV53838.1    KRK04552.1    KRK04553.1    SPP83354.1    GFDL01002222    JAV32823.1    KRG01713.1    SPP83357.1    SPP83355.1    KRK04556.1    GFDL01002210    JAV32835.1    KRT01418.1    GFDL01002214    JAV32831.1    CH940650    EDW66907.2    DS235849    EEB18657.1    GALX01001410    JAB67056.1    KRF82995.1    KRG01714.1    KRG01712.1    KQ971343    EFA04170.2    UFQT01002219    SSX32950.1    CH964272    EDW84792.2   

Proteomes

UP000053268    UP000007151    UP000092461    UP000008820    UP000069940    UP000075884    + More
UP000075886    UP000030765    UP000075900    UP000075880    UP000069272    UP000076407    UP000075882    UP000007062    UP000075903    UP000095301    UP000000673    UP000192221    UP000007801    UP000000304    UP000000803    UP000002282    UP000268350    UP000001819    UP000092444    UP000075881    UP000092553    UP000001070    UP000009192    UP000095300    UP000183832    UP000008711    UP000008792    UP000009046    UP000007266    UP000007798   

PRIDE

Q7KS16    Q9VC62    A9UNH8   

Pfam

PF00168   C2        + More
PF17047   SMP_LBD
PF02233   PNTB
PF05222   AlaDh_PNT_N
PF01262   AlaDh_PNT_C
PF12769   PNTB_4TM
PF05346   DUF747

Interpro

IPR037749   Ext_Synaptotagmin_C2B        + More
IPR035892   C2_domain_sf       
IPR037752   C2C_KIAA1228       
IPR000008   C2_dom       
IPR031468   SMP_LBD       
IPR039010   Synaptotagmin_SMP       
IPR037733   Ext_Synaptotagmin_C2A       
IPR034300   PNTB-like       
IPR026255   NADP_transhyd_a       
IPR036291   NAD(P)-bd_dom_sf       
IPR007698   AlaDH/PNT_NAD(H)-bd       
IPR007886   AlaDH/PNT_N       
IPR029035   DHS-like_NAD/FAD-binding_dom       
IPR024605   NADP_transhyd_a_C       
IPR008010   Tatp1       
IPR004827   bZIP       

SUPFAM

SSF52467   SSF52467        + More
SSF51735   SSF51735       

Gene 3D

2.60.40.150    

CDD

cd04050  C2B_Synaptotagmin-like
cd04030  C2C_KIAA1228
cd08391  C2A_C2C_Synaptotagmin_like

ProteinModelPortal

A0A1E1WHH0   A0A1E1WVZ1   A0A1E1WR37   A0A194PJ99   A0A212EP34   A0A1B0CUF4   + More
A0A1S4FLH5   Q16WM9   A0A023EW26   A0A182G462   A0A1Q3FZ48   A0A2M4BD42   A0A2M4BDD3   A0A182N5H2   A0A2M4BDK5   A0A2M4BDE8   A0A182QM74   A0A1L8DZX3   A0A084W4Z9   A0A182R5P9   A0A182J284   A0A2M3YYD3   A0A182FKR4   A0A2M4A0R3   A0A2M4A0N4   A0A182WVD1   A0A182LB03   A0A453Z2A5   Q5TVA9   A0A182UYE8   A0A0K8WH19   A0A1L8DZP3   T1P7K2   A0A1I8M6J8   A0A034VAE4   A0A034VBK8   A0A034VD48   W5JAG8   A0A1W4UT63   B3N1S0   B4QT78   W8B3N3   W8BVK5   A0A1B6M122   A0A1Q3FZ41   Q7KS16   Q9VC62   B4PVS6   A0A0A1WIF5   A0A0R1E5U4   A0A1W4V6I4   A9UNH8   A0A0P8ZJE0   A0A0A1X4F3   U5EHK3   A0A0P8XZD3   A0A1L8E098   A0A3B0KCB9   A0A3B0JQX0   Q293H6   A0A1B0GDH3   A0A0B4KGU9   A0A182JSB2   A0A1W4USS3   A0A0M5J2D6   A0A0P9BTA2   B4JG26   B4KB48   A0A0R1E5U3   A0A1W4V5I1   A0A0R3NKG2   A0A1I8Q3P6   A0A1J1IG23   A0A0B4K6F9   A0A1J1IJH6   A0A1J1IG34   B3P718   A0A0R1E5T7   A0A3B0JM38   A0A1Q3FZ65   A0A0Q9XB46   A0A3B0JM70   A0A3B0JM99   A0A0R1E5T6   A0A1Q3FZ30   A0A0R3NKF1   A0A1Q3FZ44   B4LYB1   E0VZ51   V5IAC8   A0A0Q9WEU1   A0A0Q9XAA2   A0A0Q9X0T2   D6WLV7   A0A336MS91   B4NIG9   A0A1I8Q3P9   A0A1I8Q3M4   A0A1I8Q3N9  

PDB

4P42     E-value=5.79485e-94,     Score=881

KEGG

101738602    no KO assigned | (RefSeq) extended synaptotagmin-1

GO

GO:0016021   GO:0006869   GO:0061817   GO:0008289   GO:1902600   GO:0008746   GO:0016301   GO:0031210   GO:0035091   GO:0005509   GO:0031234   GO:0005544   GO:0008429   GO:0031227   GO:0046907   GO:0016079   GO:0008021   GO:0005887   GO:0003700   GO:0005515   GO:0008750   GO:0050661   GO:0005254   GO:0006811   GO:0016020   GO:0016876   GO:0043039  

Length:

823

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.77908

Exp number, first 60 AAs:

21.97969

Total prob of N-in:

0.96576

POSSIBLE N-term signal

sequence

inside

1  -  37

TMhelix

38  -  60

outside

61  -  823

 

 

Pi

262.464055

Theta

195.731485

Tajima's D

1.000226

CLR

0.07247

CSRT

0.656367181640918

Interpretation

Uncertain