SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO09056
Annotation
Nipped-B-like_B?_partial_[Charadrius_vociferus]
Full name
Segregation and condensation protein A      
Location in the cell
PlasmaMembrane   Reliability : 1.191
 

Sequence

CDS
ATGGAAAAACTTCGAACTGTTGTCTATAGACCGAAACAACTGTTCCAACTGTTTCAACTATTCCACAATATTCCATATGTTGCTTTGTTCCATTCCACAGTAAACAATCAGAAACGAAACAGTTTGGAACAAGCTCTTTTCCTTTTTCACGCTGTTGTATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCTGTTATATTGGAACAGACTGTTATATTGGAACAGGCTGTTATATTGGAACAGGCGCGCCAAGCACTCGAGCACGATTTTGATATGATTCAGTCATGCATTTTACAATGA
Protein
MEKLRTVVYRPKQLFQLFQLFHNIPYVALFHSTVNNQKRNSLEQALFLFHAVVLEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQAVILEQTVILEQAVILEQARQALEHDFDMIQSCILQ

Summary

Description
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
Subunit
Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Belongs to the ScpA family.
Belongs to the FtsK/SpoIIIE/SftA family.
Pfam
PF00132   Hexapep        + More
PF08772   NOB1_Zn_bind
PF17146   PIN_6
PF00001   7tm_1
PF02616   SMC_ScpA
PF00612   IQ
PF01381   HTH_3
PF03448   MgtE_N
PF01580   FtsK_SpoIIIE
PF17854   FtsK_alpha
PF09397   FtsK_gamma
Interpro
IPR011004   Trimer_LpxA-like_sf        + More
IPR001451   Hexapep       
IPR018357   Hexapep_transf_CS       
IPR039907   NOB1       
IPR014881   NOB1_Zn-bd       
IPR036283   NOB1_Zf-like_sf       
IPR033411   Ribonuclease_PIN       
IPR017452   GPCR_Rhodpsn_7TM       
IPR000276   GPCR_Rhodpsn       
IPR027669   P2Y8_rcpt       
IPR003768   ScpA       
IPR000048   IQ_motif_EF-hand-BS       
IPR023299   ATPase_P-typ_cyto_dom_N       
IPR023214   HAD_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR010982   Lambda_DNA-bd_dom_sf       
IPR001387   Cro/C1-type_HTH       
IPR038787   SRRM5       
IPR006668   Mg_transptr_MgtE_intracell_dom       
IPR027417   P-loop_NTPase       
IPR018541   Ftsk_gamma       
IPR002543   FtsK_dom       
IPR041027   FtsK_alpha       
IPR036388   WH-like_DNA-bd_sf       
IPR036390   WH_DNA-bd_sf       
SUPFAM
SSF51161   SSF51161        + More
SSF144206   SSF144206       
SSF48452   SSF48452       
SSF47413   SSF47413       
SSF81660   SSF81660       
SSF46785   SSF46785       
SSF52540   SSF52540       

Ontologies

Topology

Subcellular location
Cytoplasm  
Length:
188
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
1.36014
Exp number, first 60 AAs:
1.2214
Total prob of N-in:
0.31516
outside
1  -  188
 
 

Population Genetic Test Statistics

Pi
232.394463
Theta
172.210643
Tajima's D
1.099341
CLR
0.770164
CSRT
0.690915454227289
Interpretation
Uncertain
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