Silkworm Genome Informatics Database

Gene

KWMTBOMO09019

Annotation

corticotropin-releasing_factor-like_diuretic_hormone_isoform_DH34_precursor_[Bombyx_mori]

Location

Bomo_Chr15(+):9766836-9806370 View in EpiBrowser

Full name

Diuretic hormone 41       + More
Diuretic hormone 45
Diuretic hormone 1

Alternative Name

Diuretic peptide 1
Mas-DH

Location in the cell

Extracellular Reliability : 2.444

CDS

ATGTGGTGGGCAGTATGGTGCGCGGCGATGGTGGCCGGCAGCGTGTTCACTGCAGCGGCACCCCCAACTGACTCCATCGACCTCATGCAAATGGATCCTTCTCTAGCTGACGATGAAAGTCTGGGATTTGCAATGCAATCTCTGAGCGGTCGTTACGCCGCTGCTCCCTGGCTCTACCTTCTTGCTGACGTGTCACACGACCCCCAGGTTCGTAGCGAGATGCAGGCGCGTTCACGTCGCTCGTTCTCCGTGAACCCCGCAGTTGACACCCTACAGCGTGGAGCATACAACCACTTTTTGGAGAAAGTAGTTCAAAGCAACAGGGACTACCTCAATAGAATCGGCAAGAGAGATTCGTGGAAGATTCTGACTGAAAACTGA

Protein

MWWAVWCAAMVAGSVFTAAAPPTDSIDLMQMDPSLADDESLGFAMQSLSGRYAAAPWLYLLADVSHDPQVRSEMQARSRRSFSVNPAVDTLQRGAYNHFLEKVVQSNRDYLNRIGKRDSWKILTEN

Description

Regulation of fluid secretion.
Diuretic hormone 41: Regulation of fluid secretion.
Diuretic hormone 45: Regulation of fluid secretion.

Similarity

Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.

Keywords

Amidation Cleavage on pair of basic residues Complete proteome Hormone Reference proteome Secreted Signal Direct protein sequencing Neuropeptide

Feature

peptide Diuretic hormone 41

Uniprot

B3IUD9 B3IUD8 B3IUE0 M4QFY8 A0A194PK26 A0A0S1U0H5 + More
A0A212FFZ1 A0A2H1V8C4 H9JE15 M4QEL3 P21819 A0A2A4K6K5 C0HKT4 A0A0S1U2G2 A0A0S1U1D6 D9HQ84 A0A3S2M3M4 C0HKT5

Pubmed

26354079 22118469 19121390 1279702 16594029 29466015 + More
20375075

EMBL

AB298935 BAG50374.1 AB298934 BAG50373.1 AB298936 BAG50375.1 + More
KC340923 AGH25555.1 KQ459602 KPI93373.1 KT005966 ALM30317.1 AGBW02008743 OWR52647.1 ODYU01001188 SOQ37059.1 BABH01002493 KC340922 AGH25554.1 L04628 NWSH01000076 PCG79871.1 KT005965 ALM30316.1 KT005967 ALM30318.1 HM023839 ADJ58572.1 RSAL01000046 RVE50569.1

Proteomes

UP000005204 UP000053268 UP000007151 UP000218220 UP000283053

PRIDE

B3IUD9 B3IUD8 B3IUE0 H9JE15

Pfam

PF00473 CRF

Interpro

IPR000187 CRF + More
IPR018446 Corticotropin-releasing_fac_CS

ProteinModelPortal

B3IUD9 B3IUD8 B3IUE0 M4QFY8 A0A194PK26 A0A0S1U0H5 + More
A0A212FFZ1 A0A2H1V8C4 H9JE15 M4QEL3 P21819 A0A2A4K6K5 C0HKT4 A0A0S1U2G2 A0A0S1U1D6 D9HQ84 A0A3S2M3M4 C0HKT5

KEGG

100174841 K23142 urcortin | (RefSeq) CRF-DH; corticotropin-releasing factor-like diuretic hormone

PATHWAY

04080 Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0007589 GO:0008613 GO:0005576 GO:0005179 GO:0007218

Subcellular location

Secreted

SignalP

Position: 1 - 19, Likelihood: 0.980641

Length:

126

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

13.4671

Exp number, first 60 AAs:

13.36756

Total prob of N-in:

0.72158

POSSIBLE N-term signal

sequence

outside

1 - 126

Pi

243.909155

Theta

179.081055

Tajima's D

0.997782

CLR

0.388529

CSRT

0.660066996650167

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics