Gene

KWMTBOMO08988

Pre Gene Modal

BGIBMGA007785

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_multidrug_resistance-associated_protein_4_[Bombyx_mori]

Location

Bomo_Chr15(-):9230273-9271571      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.705

CDS

ATGGAGTCAAAAGTAGTGTTGAACAATAAGAATCCTCACGATGAAGCTAATATCCTGTCGAAGACGTTTTTAACGTGGAGTTTTACTTTATTCAAAAGGGGTTATAAACAGGGCATTTCTATCGACGACTTATGGCAGGCTCGTGGGGCAGATCATTCGAAGCAACTCGGCGATCGTCTTGAAGTAGCCTGGGAAAGAGAGTTAGAAAGAGCCAAACAGACTGGTACAAAACCATCTTTCTCGAAAGCGATCATTCGCTCATTCTGGCTCGAATATATGATTTGCGGCATATTTGTTGGTTTTCTCTTTATCGTATTATGGCCACTGGTTCCGTTTACACTAGCATTGTTTATCGGATATTTCTCTGGAGAAAAATCACCTGAAAATTATAAAAACGCTCACATCTACAATTTCTTGATGAACTTTTTGAGTATAACGACGTCTTTAATGTTAAATCATTTACAACTTAGTCAGGGGAGAGTCGGTATGCGGATAAGGATTGCTAGCTGCTCGTTACTATATAGAAAGATTCTCAAACTTGACAGGACAGGATTAGCTAAAACAGAGCCCGGTCAAGTGATTAATCTGATGTCAAACGATGTTAATCGATTTGATTTGGTTGTTTTGTTTTTGAATTACATCTGGGTAATGCCTATTGTTGTACCTGTTGTTTCGTATCTCGTCTGGCAGCATATAGGCTGGGCCACACTTGCAGCGCTCATTGTAATATTTTTACAAACAGTTGTCGTGCAAGCGTATCTAAGTAATATGCAAGGTGTTCTTCGTGGAAAAATTGCGAAACGCACCGATGAGAGAGTAAAAGTTATGAGCGAATTGGTGAACGGAGTTCAAGTAATCAAAATGTATGCTTGGGAAAAACCGTTTGAGAAACTCGTTGATAAACTGAGAAAGCTCGAAGTGCATTACATAATGCGAACGTCCATGATCAAAGGTTTTTCAACAGCACTGAGCGTGTTCACGGAGCGTTTCATACTTTTCGCGGCCATCGTCGCATTCGTAGTGATGGGGGGCGAAATACGTTCAGAAATAACTTTCTCATTAGTGCAGTACTTCAATCTTTTGCAACTCGCCTGTAACATATTCTTTCCCTTGGCTTTAGCATTTCTTGCTGAGTCAAAAGTCTCAGTGAGTCGTTTGGAGGAATTTCTGTTGTTGGACGAGTTAGAACAAACTAAGCAAAATGAGCCTATCAAAGCCGCAATGGACTCTAAACTCATTTTGACCAATGGAAACGCAAAAGACACTGAGAAAATTAAATCGAAATCAACTGGTTTAAGTTTGACCGGAGTTTCGGCCAGTTGGTCAACTGATCCAATAGTCCACACATTGAGAAACATTACGTTTTCCGCTGAACCAGGAGAATTTGTTGGGATCGCCGGTCTCGTTGGTGCCGGTAAGTCGTCTCTGCTACAAGTGCTCCTGGGAGAACTGAAGCCATCTCAGGGGACCGTATCATTGGATGGTGCGCGTATTTCTTACGCAAGTCAAGAGCCGTGGCTCTTCGTGGCGACGATTAGACAGAACATCTTGTTCGGCTTACCATACGATAAAACACGTTACAAGAAGGTGGTGACTGCGTGCGCTCTGCTGCGGGACTTCGAGCAGTTGCCGGCGGGAGACTGCACGCTGGTCGGCGAGCGCGGCACCAGTCTCAGCGGGGGGCAGCGGGCGCGGGTGGGACTCGCGCGTGCCTGCTACAGACAAGCCGACATATATCTCCTCGACGATCCATTGTCAGCGGTGGACACGCATGTTGGCAAACATCTCGTTTCCGAATGTGTGAATGGATTGCTGCAGAACCACACCCGCATTCTGGTCACACATCAGTTGCATCACCTCAAAACCGCTGATAAAGTCATCATTCTGCGTAATGGAGAAATTGAAATGCAAGGAAAATTCGAAGAGGCGTCACGCTGTCCACTCTTTTCTGAAATGGAAGAGGAAGATGAACCCGATGAAAAAAATCTAAAACATCTCAGGAAACGAACTATCTCCATTCAGTCCAAAACGAGTGTTAGTACAACACACGATGGAAGCCAGGTTGATGTTGAAGAAGATGAGCAGAAGGAGTCCGAAGAACTAACTGGATCTGGGAGAGTATCAGGATTAGTATACATGAGCTACTTCCGTGCCGGCGGTGGTTGGGCACTTTTGTTCTGGACTTTGTTTTCCATCATTATTGCACAAGCCGTGACGTCAATGAGCGATATGTGGCTCACACACTGGATGAACGACGTGGAAGTGACGTACTTGACACCGACTTTTGAAACGGATCTCCTTACTGATCGCAACGAAACGAATAATTTAAATTTAACGAGTGAAGTTCCCACAGTCGTTGACTCGGCCGCCTTCCCGCCAAACTTAACAGTGATCGGCACGATCATGAAAACGGCCATGGCCATACAGAACGCGACGGAAACGGAACGTGAAAATGTAAATCACTCGTATTACATTTACATATGGGCGATCGGAATATTGGGTTGCATAATATTAACAACGGCCAGATCGATGATGTTCCTGTGGGTGTGTATGCGGAGCTCTATAAAACTCCACAACCAAATGTTCAGTAATATTATCGCGGCGACGATGCGCTTCTTCGACACAAACCCGTCCGGACGAGTTCTCAACAGATTCTCGAAGGACATGGGCGTAGTCGACGAGATACTGCCCCGGATGTTTTTAGACAGCATACAGATATTTATGGTGATGATCGGTATATTAGTGATGGTCGCTATAGTGAGCCCCTTCATGATGCTTACGACGGTAGTGTGCGGGGTGCTCATGTATCTGTGGACCGTCGTTTACCTCACCACCGCTCAAGCTGTAAAAAGGGTCGAAGGCATATCTCGGAGCCCTGTGTTCTCCCACGTGTCGGCCAGCATGGCGGGCCTGTCCACCGTGAGGGCTTGTAACGCTGAAATGATGCTGGCGGATCAATTCGACGATAAGCAAGACGTACACACAGCCGCCTGGTATTTAACTCTGGTCACAAACACTGCTTTCTCGATCTGGCTCAGTCTCATATCTGCCTTGTACGTTATAGTTGTGGCCTATACATTTTTACTACTAGATGACGGAACAACGAAATCTGGAAACGTCGGTCTGGCGTTAAGTCAAGGATTAATTTTGGTGAACATGGTTCAGTATGGTATCAAACAGACAACGGAGGTTATATCGCAAATGACCAGCGTCGAAAGAGTGATACAATTCACGTCGCTGCCTCTCGAGAAGACGGAAGGGCCCGCCCCGCCGCCGAGCTGGCCGCAGCGCGCTCGCGTCGTATTCAAGGATCTCAATCTTCGATACGACAAAGATTCCGACCCGGTGCTCAGAAACCTTAACATCATCATTGAAAGCGGCTGGAAGGTCGGTGTCGTCGGGCGCACCGGTGCCGGTAAATCATCATTGATCTCGGCTTTGTTCCGATTGGCTCCGATCGAGGGTCATATTTATATCGATGATGTTGAAACTGGAGAAATCGCTCTTAAAGCATTGCGCTCGAAGATTTCCATCATTCCTCAAGAACCAGTCCTGTTTTCTGCTACTTTGCGATACAATTTGGATCCATTCGATAAATACACTGACGCTGAAATATGGACCGCCCTAGAACAGGTTGAACTCAAAAATACTGTGACGTCATTATCATCATCAGTCGCTTCTGGTGGATCCAATTTTAGTGCTGGACAACGGCAGCTTCTGTGCCTGGCCCGAGCGGCCCTTGCTAGAAATAGACTACTCGTGTTGGATGAAGCTACCGCTAATGTAGATCCGAATACTGATGCACTGATCCAGAAGTCTATTCGCAAACATTTTGCGGACTGCACCGTTGTCACAGTCGCCCATCGACTACACACCGTTGCGGATTCTGATCGAGTTGTGGTCATGGAAGCAGGCCAGATCGTCGAATGTGGCCACCCTTACGAGCTACTTAAGAACGATAACGGGCATTTCTCGAAAATGGTTAAACAATTGGGTCCCGCCTCAGAGCAGAGCCTTAGAGAACTTGCGCGGGACGCACACGCACAACACATACAATACGTCGACGCGGACGACCAGGATAAAACGAAATAA

Protein

MESKVVLNNKNPHDEANILSKTFLTWSFTLFKRGYKQGISIDDLWQARGADHSKQLGDRLEVAWERELERAKQTGTKPSFSKAIIRSFWLEYMICGIFVGFLFIVLWPLVPFTLALFIGYFSGEKSPENYKNAHIYNFLMNFLSITTSLMLNHLQLSQGRVGMRIRIASCSLLYRKILKLDRTGLAKTEPGQVINLMSNDVNRFDLVVLFLNYIWVMPIVVPVVSYLVWQHIGWATLAALIVIFLQTVVVQAYLSNMQGVLRGKIAKRTDERVKVMSELVNGVQVIKMYAWEKPFEKLVDKLRKLEVHYIMRTSMIKGFSTALSVFTERFILFAAIVAFVVMGGEIRSEITFSLVQYFNLLQLACNIFFPLALAFLAESKVSVSRLEEFLLLDELEQTKQNEPIKAAMDSKLILTNGNAKDTEKIKSKSTGLSLTGVSASWSTDPIVHTLRNITFSAEPGEFVGIAGLVGAGKSSLLQVLLGELKPSQGTVSLDGARISYASQEPWLFVATIRQNILFGLPYDKTRYKKVVTACALLRDFEQLPAGDCTLVGERGTSLSGGQRARVGLARACYRQADIYLLDDPLSAVDTHVGKHLVSECVNGLLQNHTRILVTHQLHHLKTADKVIILRNGEIEMQGKFEEASRCPLFSEMEEEDEPDEKNLKHLRKRTISIQSKTSVSTTHDGSQVDVEEDEQKESEELTGSGRVSGLVYMSYFRAGGGWALLFWTLFSIIIAQAVTSMSDMWLTHWMNDVEVTYLTPTFETDLLTDRNETNNLNLTSEVPTVVDSAAFPPNLTVIGTIMKTAMAIQNATETERENVNHSYYIYIWAIGILGCIILTTARSMMFLWVCMRSSIKLHNQMFSNIIAATMRFFDTNPSGRVLNRFSKDMGVVDEILPRMFLDSIQIFMVMIGILVMVAIVSPFMMLTTVVCGVLMYLWTVVYLTTAQAVKRVEGISRSPVFSHVSASMAGLSTVRACNAEMMLADQFDDKQDVHTAAWYLTLVTNTAFSIWLSLISALYVIVVAYTFLLLDDGTTKSGNVGLALSQGLILVNMVQYGIKQTTEVISQMTSVERVIQFTSLPLEKTEGPAPPPSWPQRARVVFKDLNLRYDKDSDPVLRNLNIIIESGWKVGVVGRTGAGKSSLISALFRLAPIEGHIYIDDVETGEIALKALRSKISIIPQEPVLFSATLRYNLDPFDKYTDAEIWTALEQVELKNTVTSLSSSVASGGSNFSAGQRQLLCLARAALARNRLLVLDEATANVDPNTDALIQKSIRKHFADCTVVTVAHRLHTVADSDRVVVMEAGQIVECGHPYELLKNDNGHFSKMVKQLGPASEQSLRELARDAHAQHIQYVDADDQDKTK

Uniprot

A0A0E3ZB25   A0A194PIU3   A0A2W1BFZ5   D2K6M7   A0A2A4K224   D2K6M6   + More
A0A437B2W7   A0A2A4J643   A0A0E3UVD8   A0A194RCF4   A0A2A4K3R8   A0A1Y1KY01   D6WLS5   A0A0U9HSH2   A0A0C9R3H3   A0A067R1W1   A0A1W4WE54   A0A0M8ZRW3   A0A154PH22   A0A2J7PFD7   A0A026WLA8   A0A088AFE6   A0A0E3UUF7   A0A3G1PY98   A0A3S2TFR5   V5TF62   A0A151IYU4   D6WJN5   A0A2A3ED65   V5I8K8   U5JE76   V5TEA6   A0A0C9R1Z8   A0A158NMX0   A0A151WHK6   A0A0C9RET5   F4WTF6   A0A195BC45   A0A2H1X0D3   U4URU5   A0A0T6AV71   A0A3L8DIZ7   A0A232EXT2   K7IUA5   A0A2J7PFE3   A0A1W4WP56   A0A232F6R5   A0A195EWQ3   A0A1W4WE28   A0A146LYI9   A0A2J7PEN6   A0A0A9WJ51   A0A023F3H7   A0A0L7QUH9   A0A158NLT2   A0A2J7PVQ7   A0A336K0I7   A0A067R9U7   A0A1Y1LFL8   A0A0P4W3Q5   A0A182MAA3   K7IUA6   A0A182NJ65   A0A1W5PZ91   Q178E8   A0A182WC63   A0A067RQX2   A0A0V0G5R1   A0A182GUU2   A0A336LRH9   A0A182Q5F7   A0A1Y1M6K8   A0A069DYA9   A0A1Y1M4A8   J9KIT1   A0A1A9V725   A0A182RML1   A0A0L0CKR5   A0A182VRI3   A0A2J7R104   A0A1L8DV41   Q7Q5I0   A0A1L8DUP6   A0A1B0FJ40   W8AYC4   A0A1S4GS60   A0A182MS57   A0A182V3W3   A0A182TI84   A0A182I405   A0A182VF60   A0A2J7QE18   A0A182LCH3   A0A1I8JUN0   A0A067RUE2   A0A182HJA2  

Pubmed

25875245    26354079    28756777    28004739    18362917    19820115    + More
24845553    24508170    24302568    21347285    21719571    23537049    30249741    28648823    20075255    26823975    25401762    25474469    27129103    28416297    17510324    26483478    26334808    26108605    12364791    24495485    20966253   

EMBL

KM245563    AKC96182.1    KQ459602    KPI93341.1    KZ150089    PZC73708.1    + More
GU182416    ACZ64280.1    NWSH01000215    PCG78321.1    GU182415    ACZ64279.1    RSAL01000187    RVE44780.1    NWSH01003134    PCG66893.1    KM245564    AKC96183.1    KQ460615    KPJ13586.1    PCG78320.1    GEZM01073523    JAV65030.1    KQ971343    EFA04157.2    GARF01000038    JAC88908.1    GBYB01007337    JAG77104.1    KK853083    KDR11623.1    KQ435879    KOX69880.1    KQ434902    KZC11097.1    NEVH01025663    PNF15046.1    KK107159    EZA56728.1    KM245560    AKC96179.1    KY701524    AVV62497.1    RVE44791.1    KF278997    AHB63235.1    KQ980745    KYN13667.1    EFA04472.2    KZ288287    PBC29424.1    GALX01004510    JAB63956.1    KC112554    AGN29368.1    KF278996    AHB63234.1    GBYB01006857    JAG76624.1    ADTU01020829    KQ983115    KYQ47297.1    GBYB01006860    JAG76627.1    GL888334    EGI62548.1    KQ976529    KYM81765.1    ODYU01012016    SOQ58094.1    KB632335    ERL92805.1    LJIG01022728    KRT79020.1    QOIP01000007    RLU20387.1    NNAY01001666    OXU23276.1    AAZX01003864    PNF15053.1    NNAY01000861    OXU26170.1    KQ981940    KYN32705.1    GDHC01006604    JAQ12025.1    NEVH01026090    PNF14801.1    GBHO01036168    JAG07436.1    GBBI01002866    JAC15846.1    KQ414735    KOC62298.1    ADTU01019804    NEVH01020943    PNF20422.1    UFQS01000040    UFQT01000040    SSW98269.1    SSX18655.1    KK852607    KDR20353.1    GEZM01061568    JAV70366.1    GDKW01000545    JAI56050.1    AXCM01002561    KY250427    APG42670.1    CH477365    EAT42553.1    KK852521    KDR22129.1    GECL01002731    JAP03393.1    JXUM01089709    JXUM01089710    UFQS01000118    UFQT01000118    SSX00015.1    SSX20395.1    AXCN02000455    GEZM01041017    JAV80648.1    GBGD01000127    JAC88762.1    GEZM01041016    JAV80649.1    ABLF02035624    JRES01000264    KNC32832.1    NEVH01008214    PNF34507.1    GFDF01003929    JAV10155.1    AAAB01008960    EAA10720.3    GFDF01003930    JAV10154.1    CCAG010022756    GAMC01020689    GAMC01020688    GAMC01020687    JAB85866.1    AXCM01014272    APCN01002262    APCN01002263    NEVH01015354    PNF26826.1    KK852413    KDR24430.1    APCN01002134    APCN01002135   

Proteomes

UP000053268    UP000218220    UP000283053    UP000053240    UP000007266    UP000027135    + More
UP000192223    UP000053105    UP000076502    UP000235965    UP000053097    UP000005203    UP000078492    UP000242457    UP000005205    UP000075809    UP000007755    UP000078540    UP000030742    UP000279307    UP000215335    UP000002358    UP000078541    UP000053825    UP000075883    UP000075884    UP000008820    UP000075920    UP000069940    UP000075886    UP000007819    UP000078200    UP000075900    UP000037069    UP000007062    UP000092444    UP000075903    UP000075902    UP000075840    UP000075882   

Pfam

PF00005   ABC_tran        + More
PF00664   ABC_membrane
PF00096   zf-C2H2

Interpro

IPR036640   ABC1_TM_sf        + More
IPR027417   P-loop_NTPase       
IPR011527   ABC1_TM_dom       
IPR003439   ABC_transporter-like       
IPR003593   AAA+_ATPase       
IPR017871   ABC_transporter_CS       
IPR009147   CFTR/ABCC7       
IPR000788   RNR_lg_C       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF90123   SSF90123        + More
SSF52540   SSF52540       
SSF57667   SSF57667       

Gene 3D

1.20.1560.10    

ProteinModelPortal

A0A0E3ZB25   A0A194PIU3   A0A2W1BFZ5   D2K6M7   A0A2A4K224   D2K6M6   + More
A0A437B2W7   A0A2A4J643   A0A0E3UVD8   A0A194RCF4   A0A2A4K3R8   A0A1Y1KY01   D6WLS5   A0A0U9HSH2   A0A0C9R3H3   A0A067R1W1   A0A1W4WE54   A0A0M8ZRW3   A0A154PH22   A0A2J7PFD7   A0A026WLA8   A0A088AFE6   A0A0E3UUF7   A0A3G1PY98   A0A3S2TFR5   V5TF62   A0A151IYU4   D6WJN5   A0A2A3ED65   V5I8K8   U5JE76   V5TEA6   A0A0C9R1Z8   A0A158NMX0   A0A151WHK6   A0A0C9RET5   F4WTF6   A0A195BC45   A0A2H1X0D3   U4URU5   A0A0T6AV71   A0A3L8DIZ7   A0A232EXT2   K7IUA5   A0A2J7PFE3   A0A1W4WP56   A0A232F6R5   A0A195EWQ3   A0A1W4WE28   A0A146LYI9   A0A2J7PEN6   A0A0A9WJ51   A0A023F3H7   A0A0L7QUH9   A0A158NLT2   A0A2J7PVQ7   A0A336K0I7   A0A067R9U7   A0A1Y1LFL8   A0A0P4W3Q5   A0A182MAA3   K7IUA6   A0A182NJ65   A0A1W5PZ91   Q178E8   A0A182WC63   A0A067RQX2   A0A0V0G5R1   A0A182GUU2   A0A336LRH9   A0A182Q5F7   A0A1Y1M6K8   A0A069DYA9   A0A1Y1M4A8   J9KIT1   A0A1A9V725   A0A182RML1   A0A0L0CKR5   A0A182VRI3   A0A2J7R104   A0A1L8DV41   Q7Q5I0   A0A1L8DUP6   A0A1B0FJ40   W8AYC4   A0A1S4GS60   A0A182MS57   A0A182V3W3   A0A182TI84   A0A182I405   A0A182VF60   A0A2J7QE18   A0A182LCH3   A0A1I8JUN0   A0A067RUE2   A0A182HJA2  

PDB

6C3P     E-value=1.91042e-125,     Score=1155

KEGG

101744514    no KO assigned | (RefSeq) multidrug resistance-associated protein 4

GO

GO:0016021   GO:0042626   GO:0005524   GO:0016020   GO:0055085   GO:0005743   GO:0006879   GO:0005254   GO:0055114   GO:0006260   GO:0003676   GO:0016887   GO:0006810   GO:0008237   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

Length:

1363

Number of predicted TMHs:

11

Exp number of AAs in TMHs:

254.6684

Exp number, first 60 AAs:

0.01775

Total prob of N-in:

0.99524

inside

1  -  96

TMhelix

97  -  119

outside

120  -  133

TMhelix

134  -  156

inside

157  -  205

TMhelix

206  -  228

outside

229  -  231

TMhelix

232  -  254

inside

255  -  321

TMhelix

322  -  344

outside

345  -  353

TMhelix

354  -  376

inside

377  -  717

TMhelix

718  -  740

outside

741  -  823

TMhelix

824  -  846

inside

847  -  902

TMhelix

903  -  920

outside

921  -  923

TMhelix

924  -  946

inside

947  -  1006

TMhelix

1007  -  1029

outside

1030  -  1363

 

 

Pi

222.950311

Theta

176.53918

Tajima's D

0.761123

CLR

0.747847

CSRT

0.587120643967802

Interpretation

Uncertain