Gene

KWMTBOMO08957  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007729

Annotation

PREDICTED:_serine_protease_inhibitor_6_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(+):8724808-8739772      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 2.375

CDS

ATGCTGAGGTGTCTAATTGTGGTATTGTTCGTCGTTTCAACGGTTACCAGCCAGTGCTTCTACAAAGATGACTCTTCTAAAAAGCTGAATCCGGAGGCGCGGACCGCTTTGTATAACGGCCAGCTGGGATTCACGTTAAATCTTTTTAATACAATCAACGACGCTGTACCCGATGACAACATATTCTTCTCACCTTTCTCAGTATACCACTCATTGCTACTTGCATATCTCTCATCCGGCGGACAAACTGAAGAAGCTCTGAGGAAATCTTTAGAAATCGAGGATGGATTGGATAAAATAAATTTAATGACTGCGTATAAAGTAGACAAACGAGCTCGCGGTATAAACAACAACAGCGATAGTTATGAGTTTACGAGCGCGAACAAACTGTTCGCAGCTGATGATCTTAATGTGCGACAATGCATGCTTGATCTCTTTGCCGAAGATCTCGAGACTTTGAATTTCCGGGAAAATCCTGGCGCTGCCCGTGACTACATCAATAGCTGGGTGTCTCGTGTTACCAAGAACCATATATCTGATTTAATTCCCGCCTCTGGGATATCTCAGACTACTAGACTCGTCCTGGCCAACGCTGCTTACTTTAAAGGTGTTTGGGCGTCTAAATTCCCTGCCGAGAGAACAAGAAAAGAAGCTTTCTTCGTTTCGGAAACCAGACAAACTCTTGTTCCGTTCATGAAACAAAAAGGAACTTTCCATTATATGGTGAGCGATGAACTCGGCGCACAGATTTTGGAGCTTCCGTACAAAGGCAGTGACATCAGCATGTACATTCTACTACCGCCTTACTCTATGAAGGAAGGAGTGAGTAATATTATCGCTAACTTGACCCCCGAGCGTCTGGCTGCTGTGGTAGAAGAGAGCTATATGGGCAGAGAAGTCATCGTTGAGATTCCTAAGTTTTCCATGGAGAGGTCGCTACCACTTAGAGAAATCCTGGAAAAACTTGGGGTCGGAGATCTGTTCAATGGAACAGCTGACTTCAGTACGTTGACAGAGCAACACGGCATTCTGTTCGATGATGCTATACATAAAGCAAAGATTGACGTTAACGAAGAAGGTACTGTGGCAGCAGCTGCGACCGCCATCTTCGGGTTCCGTTCGTCTCGACCTGCAGAACCGACCCGCTTCGTTGCCAACTTCCCTTTCGTATACGTTCTATACGAACGACCAACCAGTTCTATTTTGTTCATGGGCGTTTACAGGGATCCTAAGAAGTATTGA

Protein

MLRCLIVVLFVVSTVTSQCFYKDDSSKKLNPEARTALYNGQLGFTLNLFNTINDAVPDDNIFFSPFSVYHSLLLAYLSSGGQTEEALRKSLEIEDGLDKINLMTAYKVDKRARGINNNSDSYEFTSANKLFAADDLNVRQCMLDLFAEDLETLNFRENPGAARDYINSWVSRVTKNHISDLIPASGISQTTRLVLANAAYFKGVWASKFPAERTRKEAFFVSETRQTLVPFMKQKGTFHYMVSDELGAQILELPYKGSDISMYILLPPYSMKEGVSNIIANLTPERLAAVVEESYMGREVIVEIPKFSMERSLPLREILEKLGVGDLFNGTADFSTLTEQHGILFDDAIHKAKIDVNEEGTVAAAATAIFGFRSSRPAEPTRFVANFPFVYVLYERPTSSILFMGVYRDPKKY

Similarity

Belongs to the serpin family.

Uniprot

H9JDY2   A8IE37   A0A0M3SH23   A0A2H1WBV7   A0A2A4JSR0   A0A1L5J028   + More
A0A3S2NAP3   G9F9J4   A0A290Y5D8   Q56SF5   I4DIS8   A0A194PJ14   I4DMX4   A0A212EY91   S4P8U7   X2C067   A0A088SGI7   A0A2P8ZHJ8   A0A2K8JRW3   A0A2J7RHL8   R4FLP4   A0A067QXT5   A0A1V1FIU4   A0A0L7LQL0   A0A224XD42   A0A1B6G556   A0A2K8JLE4   A0A1B6I7V7   A0A1Y1L4Z8   A0A1W4X377   A0A1L8DP44   A0A1L8DPF3   A0A2R7X4P2   A0A1Y1L669   A0A0A9WH51   E0VBZ1   A0A1Q3F3K2   B0WYP6   A0A336M7S2   A0A336MAZ3   A0A411G657   Q16Z02   A0A151JVQ0   A0A0C9QWH1   A0A182GJU2   A0A336MIP5   M9ZTW6   K7J8S2   D6WMA4   A0A195CW43   A0A0T6AZB7   A0A026WI68   A0A1W4X3B7   J9JVW8   A0A0L0C3L6   A0A1W4XE12   A0A232FEZ6   A0A158NMG6   A0A1A9XW45   E2B8Y8   A0A1B0C1V4   A0A154NZU3   A0A1A9ZL45   A0A195AZT7   Q2PQP8   A0A1A9V711   A0A1B0GGD0   W8BMF4   A0A1I8P9P2   F4WI47   A0A151IZH0   A0A2H8TKZ1   A0A0Q9WEY9   B4M4L3   E2A358   A0A3L8DKQ6   A0A034V6M6   A0A0J7KK66   A0A1I9UVU9   V9IFV5   A0A0K8UH79   A0A0A1XL05   A0A2A3E2L1   A0A0A1XIV6   T1PFV3   A0A088ASF2   A0A2M4A422   B4K6U3   A0A2M4A4K5   A0A2M4AB92   A0A182QCT1   A0A2M4A7G2   A0A182FL68   A0A2M3Z5E5   A0A151X0W7   W5JHA9   A0A2M4BN50   A0A2M3ZEM1   T1DK80  

Pubmed

19121390    15691825    22651552    26354079    22118469    23622113    + More
25220661    29403074    24845553    28410430    26227816    28004739    25401762    20566863    17510324    26483478    23497397    20075255    18362917    19820115    24508170    26108605    28648823    21347285    20798317    16907828    20353571    24495485    21719571    17994087    30249741    25348373    25830018    25315136    20920257    23761445   

EMBL

BABH01002596    EU159447    ABV74209.1    KR003730    ALD62508.1    ODYU01007308    + More
SOQ49974.1    NWSH01000740    PCG74493.1    KX117919    APM86797.1    RSAL01000315    RVE42614.1    JN033739    AEW46892.1    MF944108    ATD87113.1    AY672799    AAV91026.1    AK401196    BAM17818.1    KQ459602    KPI93312.1    AK402642    BAM19264.1    AGBW02011580    OWR46462.1    GAIX01005781    JAA86779.1    JX051169    AFV09850.1    KM384737    AIO11228.1    PYGN01000056    PSN55974.1    KY031029    ATU82780.1    NEVH01003740    PNF40331.1    ACPB03021815    GAHY01001298    JAA76212.1    KK853131    KDR10950.1    FX985341    BAX07354.1    JTDY01000315    KOB77737.1    GFTR01006081    JAW10345.1    GECZ01012199    JAS57570.1    MF683351    ATU82492.1    GECU01024702    JAS83004.1    GEZM01066469    JAV67861.1    GFDF01005826    JAV08258.1    GFDF01005827    JAV08257.1    KK856492    PTY25895.1    GEZM01066470    GEZM01066468    GEZM01066467    JAV67860.1    GBHO01044684    GBHO01037751    GBRD01009683    GBRD01009682    JAF98919.1    JAG05853.1    JAG56141.1    AAZO01000908    DS235044    EEB10897.1    GFDL01012911    JAV22134.1    DS232196    EDS37156.1    UFQT01000646    SSX26080.1    SSX26079.1    MH365528    QBB01337.1    CH477505    EAT39866.1    KQ981692    KYN37890.1    GBYB01005032    JAG74799.1    JXUM01068840    KQ562520    KXJ75722.1    UFQT01001276    SSX29810.1    KC355226    AGK40926.1    KQ971343    EFA04591.1    KQ977231    KYN04757.1    LJIG01022508    KRT80205.1    KK107238    EZA54804.1    ABLF02033073    JRES01000953    KNC26841.1    NNAY01000362    OXU28887.1    ADTU01020474    ADTU01020475    GL446405    EFN87822.1    JXJN01024177    KQ434786    KZC05196.1    KQ976697    KYM77557.1    DQ307175    EZ423249    JQ312068    ABC25075.1    ADD19525.1    AFG28185.1    CCAG010017875    GAMC01012005    GAMC01012004    JAB94551.1    GL888172    EGI66140.1    KQ980710    KYN14444.1    GFXV01002904    MBW14709.1    CH940652    KRF78944.1    EDW59574.2    GL436277    EFN72133.1    QOIP01000007    RLU20489.1    GAKP01019985    GAKP01019982    GAKP01019979    GAKP01019976    JAC38976.1    LBMM01006430    KMQ90614.1    KU668684    APA05229.1    JR041172    AEY59376.1    GDHF01026277    JAI26037.1    GBXI01002621    JAD11671.1    KZ288425    PBC25947.1    GBXI01003410    JAD10882.1    KA647636    AFP62265.1    GGFK01002243    MBW35564.1    CH933806    EDW14209.1    GGFK01002368    MBW35689.1    GGFK01004740    MBW38061.1    AXCN02000238    GGFK01003361    MBW36682.1    GGFM01002917    MBW23668.1    KQ982601    KYQ54008.1    ADMH02001497    ETN62305.1    GGFJ01005301    MBW54442.1    GGFM01006245    MBW26996.1    GAMD01001081    JAB00510.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000007151    UP000245037    + More
UP000235965    UP000015103    UP000027135    UP000037510    UP000192223    UP000009046    UP000002320    UP000008820    UP000078541    UP000069940    UP000249989    UP000002358    UP000007266    UP000078542    UP000053097    UP000007819    UP000037069    UP000215335    UP000005205    UP000092443    UP000008237    UP000092460    UP000076502    UP000092445    UP000078540    UP000078200    UP000092444    UP000095300    UP000007755    UP000078492    UP000008792    UP000000311    UP000279307    UP000036403    UP000242457    UP000095301    UP000005203    UP000009192    UP000075886    UP000069272    UP000075809    UP000000673   

PRIDE

H9JDY2    A8IE37   

Pfam

PF00079   Serpin        + More
PF01770   Folate_carrier

Interpro

IPR042185   Serpin_sf_2        + More
IPR023796   Serpin_dom       
IPR036186   Serpin_sf       
IPR042178   Serpin_sf_1       
IPR000215   Serpin_fam       
IPR023795   Serpin_CS       
IPR002666   Folate_carrier       
IPR036259   MFS_trans_sf       
IPR020846   MFS_dom       

SUPFAM

SSF56574   SSF56574        + More
SSF103473   SSF103473       

Gene 3D

2.30.39.10     3.30.497.10    

CDD

cd06174  MFS

ProteinModelPortal

H9JDY2   A8IE37   A0A0M3SH23   A0A2H1WBV7   A0A2A4JSR0   A0A1L5J028   + More
A0A3S2NAP3   G9F9J4   A0A290Y5D8   Q56SF5   I4DIS8   A0A194PJ14   I4DMX4   A0A212EY91   S4P8U7   X2C067   A0A088SGI7   A0A2P8ZHJ8   A0A2K8JRW3   A0A2J7RHL8   R4FLP4   A0A067QXT5   A0A1V1FIU4   A0A0L7LQL0   A0A224XD42   A0A1B6G556   A0A2K8JLE4   A0A1B6I7V7   A0A1Y1L4Z8   A0A1W4X377   A0A1L8DP44   A0A1L8DPF3   A0A2R7X4P2   A0A1Y1L669   A0A0A9WH51   E0VBZ1   A0A1Q3F3K2   B0WYP6   A0A336M7S2   A0A336MAZ3   A0A411G657   Q16Z02   A0A151JVQ0   A0A0C9QWH1   A0A182GJU2   A0A336MIP5   M9ZTW6   K7J8S2   D6WMA4   A0A195CW43   A0A0T6AZB7   A0A026WI68   A0A1W4X3B7   J9JVW8   A0A0L0C3L6   A0A1W4XE12   A0A232FEZ6   A0A158NMG6   A0A1A9XW45   E2B8Y8   A0A1B0C1V4   A0A154NZU3   A0A1A9ZL45   A0A195AZT7   Q2PQP8   A0A1A9V711   A0A1B0GGD0   W8BMF4   A0A1I8P9P2   F4WI47   A0A151IZH0   A0A2H8TKZ1   A0A0Q9WEY9   B4M4L3   E2A358   A0A3L8DKQ6   A0A034V6M6   A0A0J7KK66   A0A1I9UVU9   V9IFV5   A0A0K8UH79   A0A0A1XL05   A0A2A3E2L1   A0A0A1XIV6   T1PFV3   A0A088ASF2   A0A2M4A422   B4K6U3   A0A2M4A4K5   A0A2M4AB92   A0A182QCT1   A0A2M4A7G2   A0A182FL68   A0A2M3Z5E5   A0A151X0W7   W5JHA9   A0A2M4BN50   A0A2M3ZEM1   T1DK80  

PDB

5CDZ     E-value=1.68451e-52,     Score=521

KEGG

100126553    no KO assigned | (RefSeq) serpin-6, BmSPN6, SPN6; serine protease inhibitor 6

GO

GO:0005615   GO:0008233   GO:0016021   GO:0004867   GO:0010951  

PANTHER

PTHR11461   PTHR10686  

SignalP

Position:   1 - 17,         Likelihood:  0.992705

 

 

Length:

413

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.48812

Exp number, first 60 AAs:

0.21434

Total prob of N-in:

0.01327

outside

1  -  413

 

 

Pi

269.448337

Theta

182.801011

Tajima's D

1.379171

CLR

0.250047

CSRT

0.759662016899155

Interpretation

Uncertain