Gene

KWMTBOMO08941  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007804

Annotation

matrix_metalloproteinase_1_isoform_1_[Bombyx_mori]

Location

Bomo_Chr15(-):8503033-8525077      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 0.962

CDS

ATGTATTTAGCACAGTACGGTTATTTAAGTCCATCAGTAAGGAATCCTTCGAGTGGACACATTATGGATGAGAGCTCGTGGAGGAGAGCCATTGCCGAATTTCAGAGCTTCGCTGGTCTTAATGCTACGGGTGAACTGGATGACCAAACGAACGAAATGATGTCATTGCCAAGGTGTGGAGTTAGAGATAAAGTAGGCTTCGGAGAGAGTCGTGCCAAAAGATACGCATTGCAAGGGTCAAGATGGCGTGTCAAAAATCTGACGTACAAGATATCCAAGTACCCATCAAGACTGAATCGCGCCGAAGTCGATGCTGAGCTTGCCAAAGCCTTCTCCGTCTGGTCTGACTACACGGATCTTACTTTCACACAAAAGAGATCCGGTCAAGTCCACATAGAAATTAGGTTTGAGAAAGGCGAGCACGGTGACGGAGATCCTTTTGATGGTCCAGGAGGCACCCTCGCCCACGCTTATTTCCCGGTGTATGGAGGTGATGCCCATTTTGATGACGCTGAGATGTGGTCCATCAATTCCCGTAGAGGAACTAATCTTTTCCAGGTAGCAGCGCATGAGTTTGGTCACTCGCTGGGTCTCTCACACAGCGATGTAAGATCCGCATTGATGGCGCCGTTTTATCGTGGTTACGATCCTGCTTTCCAACTCGATCAGGACGACGTCCAAGGAATTCAGTCGCTTTATGGCCACAAGACCCAGACAGACATTGGTGGCGGTGGCGGCGGACTGATACCTTCCGTTCCTCGAGCGACCACGCAGCAGCCGTCAGCTGAGGATCCGGCTCTCTGCGCTGATCCTCGTATTGATACTATCTTTAATTCTGCCGACGGTTCGACTTTTGTATTCAAAGGCGATCATTACTGGAGGCTAACTGAAGATGGCGTAGCGGCTGGGTACCCGCGTCTTATTTCCCGAGCCTGGCCTGGTCTACCCGGAAACATTGATGCAGCATTTACCTACAAGAACGGCAAGACTTACTTCTTTAAGGGCTCGAAGTACTGGAGGTACAATGGGCAGAAGATGGACGGGGATTACCCCAAGGATATTAGTGAAGGCTTCACCGGTATCCCAGATAACCTAGATGCGGCTTTGGTTTGGTCCGGCAATGGCAAGATCTATTTCTACAAGGGCTCGAAATTCTGGCGATTTGACCCTGCACAACGGCCTCCCGTGAAAGCTACCTACCCGAAGCCTTTGTCTAACTGGGATGGAATACCTGATAACATCGACGCCGCCTTGCAGTACACTAACGGATACACCTACTTCTTCAAGGGGGGATCATACTGGAGATTCAACGACAGATTGTTCAGCGTGGACACAGACAACCCTCAGTTCCCGCGTTCAACCGCGTTCTGGTGGTTGGGCTGCAGCAGCGCGCCGCGCGGCACCGTCGGAGGTAACGCTCGACTATCAGACGACACTGTTCCTGCCGATGACGACGTCGGGGACATTACCTTCGACGCAGGTGTAAAATCATCCGCTCCCAGATCATTCTTCTGGTTCAGGAAATAG

Protein

MYLAQYGYLSPSVRNPSSGHIMDESSWRRAIAEFQSFAGLNATGELDDQTNEMMSLPRCGVRDKVGFGESRAKRYALQGSRWRVKNLTYKISKYPSRLNRAEVDAELAKAFSVWSDYTDLTFTQKRSGQVHIEIRFEKGEHGDGDPFDGPGGTLAHAYFPVYGGDAHFDDAEMWSINSRRGTNLFQVAAHEFGHSLGLSHSDVRSALMAPFYRGYDPAFQLDQDDVQGIQSLYGHKTQTDIGGGGGGLIPSVPRATTQQPSAEDPALCADPRIDTIFNSADGSTFVFKGDHYWRLTEDGVAAGYPRLISRAWPGLPGNIDAAFTYKNGKTYFFKGSKYWRYNGQKMDGDYPKDISEGFTGIPDNLDAALVWSGNGKIYFYKGSKFWRFDPAQRPPVKATYPKPLSNWDGIPDNIDAALQYTNGYTYFFKGGSYWRFNDRLFSVDTDNPQFPRSTAFWWLGCSSAPRGTVGGNARLSDDTVPADDDVGDITFDAGVKSSAPRSFFWFRK

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M10A family.

Uniprot

B2CI48   B2CI49   H9JE57   A0A2A4JFP2   G5CZ60   A0A2A4JF64   + More
A0A2A4JEL5   A0A2A4JFL6   A0A2A4JE27   A0A437B5H5   A0A194R6V0   A0A212F4L3   A0A194PJU6   A0A1Q3FNC3   A0A1Q3FN05   A0A1Q3FN16   A0A1Q3FMU4   A0A1Q3FMS3   A0A1Q3FMY6   A0A1Q3FMU9   V5G6L1   A0A1Q3FMY0   A0A182QTZ7   A0A1Q3G4U6   A0A084WKS0   A0A1Q3G4T7   B0WWE1   A0A182N9E0   A0A182J688   A0A182K6X7   W8BIG6   A0A2C9H6V7   Q7QIJ4   A0A182G3J8   A0A2A3E310   A0A1I8MIR7   A0A182WWF5   A0A1I8MIR4   A0A182L3R1   A0A182TX16   A0A182I6N2   A0A182UZZ9   A0A1I8MIR8   A0A088AVW9   A0A310SIS7   A0A336MHW6   A0A1I8Q3R4   A0A0A1WMZ5   A0A034VPK7   A0A1I8MIR3   A0A336MF57   A0A034VPL4   A0A0K8UUG2   A0A0K8U7W3   T1PNC9   T1PDB0   Q179D2   A0A1I8MIR0   A0A0K8VXI9   A0A1B0CHM3   A0A034VL60   A0A1L8DPA9   A0A1L8DPG8   A0A0L0C2N4   A0A182FEG6   A0A1L8DPM9   A0A2M4CJD0   A0A182PIL9   A0A2M4CJ78   A0A2M3Z3D4   A0A182Y805   A0A2M4BJR9   A0A067XK10   A0A0L7QT13   A0A2A3E4T6   A0A0C9QPB4   A0A0C9QD22   A0A0C9REM2   D6WKX8   A0A1B0GCE8   A0A0R3NPE8   A0A0Q9XIN3   J9JXB6   A0A0R3NPP6   B4KTE1   A0A182MK74   A0A3B0JQP8   B4GGB5   A0A0J9UAM5   Q28XL6   A0A0Q9XEC7   A0A2H8TKH3   A0A0R3NVP4   A0A0B4JDA7   A0A0Q9XJV2   A0A1A9VT74   A0A0Q9X765   A0A3B0J335   A0A1B0BR59   A0A0Q9WE03  

Pubmed

19121390    26354079    22118469    24438588    24495485    12364791    + More
14747013    17210077    26483478    25315136    20966253    25830018    25348373    17510324    26108605    25244985    18362917    19820115    15632085    17994087    18057021    22936249    23185243    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867   

EMBL

EU496376    ACA64804.1    EU496377    ACA64805.1    BABH01002621    BABH01002622    + More
NWSH01001761    PCG70222.1    JN415760    AEQ27775.1    PCG70214.1    PCG70216.1    PCG70220.1    PCG70221.1    RSAL01000152    RVE45722.1    KQ460615    KPJ13543.1    AGBW02010348    OWR48663.1    KQ459602    KPI93298.1    GFDL01006062    JAV28983.1    GFDL01006131    JAV28914.1    GFDL01006128    JAV28917.1    GFDL01006252    JAV28793.1    GFDL01006213    JAV28832.1    GFDL01006096    JAV28949.1    GFDL01006187    JAV28858.1    GALX01002746    JAB65720.1    GFDL01006157    JAV28888.1    AXCN02000560    GFDL01000220    JAV34825.1    ATLV01024134    KE525349    KFB50814.1    GFDL01000225    JAV34820.1    DS232144    EDS36033.1    GAMC01009754    GAMC01009753    GAMC01009752    JAB96803.1    AAAB01008807    EAA04040.3    EDO64756.1    EDO64757.1    JXUM01141621    KQ569279    KXJ68684.1    KZ288411    PBC26090.1    APCN01003684    KQ760792    OAD58997.1    UFQS01001123    UFQT01001123    SSX09120.1    SSX29031.1    GBXI01014070    JAD00222.1    GAKP01014900    GAKP01014891    JAC44052.1    SSX09121.1    SSX29032.1    GAKP01014895    JAC44057.1    GDHF01022022    GDHF01012453    GDHF01007959    JAI30292.1    JAI39861.1    JAI44355.1    GDHF01029631    GDHF01020114    GDHF01002913    JAI22683.1    JAI32200.1    JAI49401.1    KA649448    AFP64077.1    KA646105    AFP60734.1    CH477354    EAT42838.1    GDHF01008701    JAI43613.1    AJWK01012495    AJWK01012496    AJWK01012497    AJWK01012498    GAKP01014896    JAC44056.1    GFDF01005782    JAV08302.1    GFDF01005793    JAV08291.1    JRES01000975    KNC26613.1    GFDF01005794    JAV08290.1    GGFL01001235    MBW65413.1    GGFL01001234    MBW65412.1    GGFM01002276    MBW23027.1    GGFJ01004060    MBW53201.1    JX399873    AGI44421.1    KQ414755    KOC61694.1    PBC26091.1    GBYB01005434    JAG75201.1    GBYB01001214    GBYB01005435    JAG70981.1    JAG75202.1    GBYB01005436    JAG75203.1    KQ971343    EFA04667.1    CCAG010007850    CCAG010007851    CM000071    KRT02977.1    CH933808    KRG04151.1    ABLF02036098    KRT02978.1    EDW08502.1    KRG04153.1    AXCM01006016    OUUW01000001    SPP75686.1    CH479183    EDW35535.1    CM002911    KMY96410.1    EAL26300.3    KRT02980.1    KRG04154.1    GFXV01002839    MBW14644.1    KRT02976.1    AE013599    ADV37248.1    KRG04152.1    KRG04150.1    SPP75685.1    JXJN01018910    CH940648    KRF79195.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000007151    UP000053268    + More
UP000075886    UP000030765    UP000002320    UP000075884    UP000075880    UP000075881    UP000076407    UP000007062    UP000069940    UP000249989    UP000242457    UP000095301    UP000075882    UP000075902    UP000075840    UP000075903    UP000005203    UP000095300    UP000008820    UP000092461    UP000037069    UP000069272    UP000075885    UP000076408    UP000053825    UP000007266    UP000092444    UP000001819    UP000009192    UP000007819    UP000075883    UP000268350    UP000008744    UP000000803    UP000078200    UP000092460    UP000008792   

PRIDE

B2CI48    B2CI49    H9JE57   

Pfam

PF00413   Peptidase_M10        + More
PF01471   PG_binding_1
PF00045   Hemopexin

Interpro

IPR006026   Peptidase_Metallo        + More
IPR036365   PGBD-like_sf       
IPR000585   Hemopexin-like_dom       
IPR018487   Hemopexin-like_repeat       
IPR036375   Hemopexin-like_dom_sf       
IPR033739   M10A_MMP       
IPR021190   Pept_M10A       
IPR018486   Hemopexin_CS       
IPR024079   MetalloPept_cat_dom_sf       
IPR002477   Peptidoglycan-bd-like       
IPR001818   Pept_M10_metallopeptidase       

SUPFAM

SSF50923   SSF50923        + More
SSF47090   SSF47090       

Gene 3D

2.110.10.10     3.40.390.10    

CDD

cd04278  ZnMc_MMP
cd00094  HX

ProteinModelPortal

B2CI48   B2CI49   H9JE57   A0A2A4JFP2   G5CZ60   A0A2A4JF64   + More
A0A2A4JEL5   A0A2A4JFL6   A0A2A4JE27   A0A437B5H5   A0A194R6V0   A0A212F4L3   A0A194PJU6   A0A1Q3FNC3   A0A1Q3FN05   A0A1Q3FN16   A0A1Q3FMU4   A0A1Q3FMS3   A0A1Q3FMY6   A0A1Q3FMU9   V5G6L1   A0A1Q3FMY0   A0A182QTZ7   A0A1Q3G4U6   A0A084WKS0   A0A1Q3G4T7   B0WWE1   A0A182N9E0   A0A182J688   A0A182K6X7   W8BIG6   A0A2C9H6V7   Q7QIJ4   A0A182G3J8   A0A2A3E310   A0A1I8MIR7   A0A182WWF5   A0A1I8MIR4   A0A182L3R1   A0A182TX16   A0A182I6N2   A0A182UZZ9   A0A1I8MIR8   A0A088AVW9   A0A310SIS7   A0A336MHW6   A0A1I8Q3R4   A0A0A1WMZ5   A0A034VPK7   A0A1I8MIR3   A0A336MF57   A0A034VPL4   A0A0K8UUG2   A0A0K8U7W3   T1PNC9   T1PDB0   Q179D2   A0A1I8MIR0   A0A0K8VXI9   A0A1B0CHM3   A0A034VL60   A0A1L8DPA9   A0A1L8DPG8   A0A0L0C2N4   A0A182FEG6   A0A1L8DPM9   A0A2M4CJD0   A0A182PIL9   A0A2M4CJ78   A0A2M3Z3D4   A0A182Y805   A0A2M4BJR9   A0A067XK10   A0A0L7QT13   A0A2A3E4T6   A0A0C9QPB4   A0A0C9QD22   A0A0C9REM2   D6WKX8   A0A1B0GCE8   A0A0R3NPE8   A0A0Q9XIN3   J9JXB6   A0A0R3NPP6   B4KTE1   A0A182MK74   A0A3B0JQP8   B4GGB5   A0A0J9UAM5   Q28XL6   A0A0Q9XEC7   A0A2H8TKH3   A0A0R3NVP4   A0A0B4JDA7   A0A0Q9XJV2   A0A1A9VT74   A0A0Q9X765   A0A3B0J335   A0A1B0BR59   A0A0Q9WE03  

PDB

1SU3     E-value=5.85001e-59,     Score=578

KEGG

100144547    K07763 matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80] | (RefSeq) Mmp1; matrix metall

GO

GO:0031012   GO:0004222   GO:0008270   GO:0016021   GO:0005615   GO:0030198   GO:0030574   GO:0007591   GO:0007419   GO:0003144   GO:0035001   GO:0035159   GO:0042246   GO:0002168   GO:0007505   GO:0030425   GO:0034769   GO:0097156   GO:0007561   GO:0045216   GO:0007155   GO:0007424   GO:0042060   GO:0071711   GO:0006508   GO:0005509   GO:0008237   GO:0043565   GO:0016876   GO:0043039  

Length:

508

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00171

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00171

outside

1  -  508

 

 

Pi

224.882217

Theta

184.637302

Tajima's D

0.645259

CLR

0.177513

CSRT

0.555722213889306

Interpretation

Uncertain