Gene

KWMTBOMO08900  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007711

Annotation

PREDICTED:_tRNA_(adenine(58)-N(1))-methyltransferase_non-catalytic_subunit_TRM6_[Bombyx_mori]

Location

Bomo_Chr15(+):7654560-7656710      View in EpiBrowser

Full name

tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6      

Location in the cell

Nuclear   Reliability : 3.911

CDS

ATGATAAGTAAAAGTAACAAAAAAGCCAGGGAATACACAGTGGAGCTAACTGACGAGGTGGTCAATCTAAAAGATGAGATTGAGATAAAATTATCTGGTAGTGATAATAGAAACATCGTTGATGATGGACTCTCACAGAAACTGACAGCTGCAGAAATCGAAGATCTGAAGAATGACGCTAATAGGGCTTCAGATATTATAGAATCTTTAATTACTAATTCAAATACCTTTCACAATAAAACAGAGTTTTCTCAGGAGAAGTATTTAAAGAAGAAAGAAAAGAAATATTTTGAATATTTACAAATATTAAAACCTAACCTAAGAACGATAGCAGAAATCATGTATAAATTAGAACCTGGTAAAGTTCAAAATTTAAGAATAGACACTTTGTCACAGATTATTACAACTGTGAATATTTATTGTGAGGGAAATCATTTATTATATGACTCTGGATCTAATGGTTTAGTTGCTGCAGCTTTATTAAGTTCTATTGGTCAAAATACTAATGGTAGACTAGTCCACATGCACCCCGGCAACATGTCTCAGAAACAAGCTCTCTTAGCTATGAATTTTCCAGAAGAACAACTTAAGAGATGTATTTCTGTTAATGTTTATTCTGCATTAAGACAATTTTATCAAGGTTGTGATACAAATTCCAATGAAAATATAAAAGAAATTCCTATCACAGAGTCAAATCAATTAAAAAGAAAATTAGTAGAAAATGACAATGAACCTAGAAGAAAAATTGCTAAACCTGATGAAGAAGTATCTGAACCAGTAATTGATGAATTAAAGGAAAATAGTAACAAAGGTGATCCAAAGATACCAAAATGGCATTTCGATAACATTTATGCTGCACAAATTCTTGAAAAAAAATTGGATTCATTGGTTATAACTTGTAAGGAAGATCCTCAAAATATATTTCTTGAATTAGTTAATTTTATCAAACCTGGCCGACCATTTGTTATTTACTATAATGTATCAGAGCCATTACAAAATCTATACTTAGCTTTAAAATCACAAAGTAATGTTGCAGCATTAAAACTCACAAGCAACTGGATGAGGAATTACCAGGTTTTGCCAGAACGAACACGTCCAGATGTTATTATGAATGGTGCTAGTGGGTATTTGTTATCAGGATATGTACTTAAATGA

Protein

MISKSNKKAREYTVELTDEVVNLKDEIEIKLSGSDNRNIVDDGLSQKLTAAEIEDLKNDANRASDIIESLITNSNTFHNKTEFSQEKYLKKKEKKYFEYLQILKPNLRTIAEIMYKLEPGKVQNLRIDTLSQIITTVNIYCEGNHLLYDSGSNGLVAAALLSSIGQNTNGRLVHMHPGNMSQKQALLAMNFPEEQLKRCISVNVYSALRQFYQGCDTNSNENIKEIPITESNQLKRKLVENDNEPRRKIAKPDEEVSEPVIDELKENSNKGDPKIPKWHFDNIYAAQILEKKLDSLVITCKEDPQNIFLELVNFIKPGRPFVIYYNVSEPLQNLYLALKSQSNVAALKLTSNWMRNYQVLPERTRPDVIMNGASGYLLSGYVLK

Description

Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

Subunit

Heterotetramer.

Similarity

Belongs to the TRM6/GCD10 family.

Uniprot

A0A2A4K145   A0A3S2LII6   A0A0N1IQ72   S4NT16   A0A212F3X7   A0A194PJP7   + More
A0A0L7LR26   U5ETR0   A0A1I8PC21   A0A1S4JVA7   A0A0L0C434   A0A1Q3EYB9   A0A1I8MWV6   A0A1I8MWV5   A0A1W4UC63   B4P0B8   A0A182M8S7   Q8MS69   B3MNZ2   B4KHU0   B4MUJ5   B4Q4Y4   A0A182W909   A0A182PTD4   A0A034WV42   A0A3B0JIU2   A0A182YMS9   B4HXU1   B0WVR7   A0A0R3NXC8   A0A182RR78   T1DL04   A0A2M4BMB7   B3N5T4   B5DV67   A0A2M4BN74   Q29PC8   B4GKI7   A0A182JTT5   A0A0M4E8P2   W8BEY1   Q17EU7   A0A0K8V879   B4JR99   W5JT56   A0A182KTK2   Q7PMA4   A0A2M4AR62   A0A182XJK6   A0A0A1WPD9   A0A1S4H2E6   A0A1A9W3X5   A0A182HRI4   A0A1A9V5P1   A0A182SAK3   B4LVE5   A0A182F3V8   A0A182UG57   A0A182IMM4   A0A182NAS2   A0A084W8N0   A0A182UUY2   A0A182GSG7   N6TZB4   U4US95   A0A1J1HHH1   D2A3U3   A0A336K501   A0A182Q2J5   A0A1B0DAR7   A0A0A1XTK9   E2BEK2   A0A087ZNU0   A0A2A3EPY7   A0A026WU60   A0A3L8DGQ8   E1ZYD0   A0A1B0G9W0   A0A0J7K997   T1GR17   K7ILS2   A0A1L8DG64   A0A195FUB5   A0A232FJ07   A0A0M8ZZM6   A0A0J7K9R4   A0A1B6HIR9   A0A1B6GEY5   E0VPC2   A0A1B6D8D8   A0A0J7K9T6   A0A0L7RB24   A0A069DUB4   A0A1B6KPM0   A0A310SMI0   A0A224XQ46  

Pubmed

26354079    23622113    22118469    26227816    26108605    25315136    + More
17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    25348373    25244985    15632085    24495485    17510324    20920257    23761445    20966253    12364791    25830018    24438588    26483478    23537049    18362917    19820115    20798317    24508170    30249741    20075255    28648823    20566863    26334808   

EMBL

NWSH01000302    PCG77614.1    RSAL01000103    RVE47404.1    KQ459937    KPJ19210.1    + More
GAIX01013827    JAA78733.1    AGBW02010474    OWR48448.1    KQ459602    KPI93253.1    JTDY01000275    KOB77953.1    GANO01002673    JAB57198.1    JRES01000933    KNC27118.1    GFDL01014755    JAV20290.1    CM000157    EDW87876.1    AXCM01000771    AE014134    AY119050    AAF52404.2    AAM50910.1    CH902620    EDV32179.1    CH933807    EDW13377.1    CH963857    EDW76190.1    CM000361    CM002910    EDX03976.1    KMY88547.1    GAKP01000877    JAC58075.1    OUUW01000006    SPP82344.1    CH480818    EDW51871.1    DS232131    EDS35674.1    CH675624    KRT05736.1    GAMD01000681    JAB00910.1    GGFJ01005086    MBW54227.1    CH954177    EDV59093.1    EDY71805.1    GGFJ01005087    MBW54228.1    CH379058    EAL34365.2    CH479184    EDW37153.1    CP012523    ALC38414.1    GAMC01018266    JAB88289.1    CH477279    EAT45004.1    GDHF01017248    JAI35066.1    CH916372    EDV99429.1    ADMH02000223    ETN67326.1    AAAB01008980    EAA14079.5    GGFK01009943    MBW43264.1    GBXI01013575    GBXI01000449    JAD00717.1    JAD13843.1    APCN01001706    CH940649    EDW63324.1    ATLV01021496    KE525319    KFB46574.1    JXUM01084972    KQ563470    KXJ73785.1    APGK01055165    KB741261    ENN71577.1    KB632344    ERL93046.1    CVRI01000004    CRK87453.1    KQ971348    EFA04885.1    UFQS01000101    UFQT01000101    SSW99587.1    SSX19967.1    AXCN02000660    AJVK01013383    GBXI01000064    JAD14228.1    GL447817    EFN85892.1    KZ288204    PBC33296.1    KK107109    EZA59176.1    QOIP01000008    RLU19614.1    GL435204    EFN73829.1    CCAG010015991    LBMM01011190    KMQ86983.1    CAQQ02197427    GFDF01008641    JAV05443.1    KQ981264    KYN44048.1    NNAY01000126    OXU30726.1    KQ435798    KOX73346.1    LBMM01011196    KMQ86976.1    GECU01033251    JAS74455.1    GECZ01008780    JAS60989.1    DS235363    EEB15228.1    GEDC01015340    JAS21958.1    LBMM01011146    KMQ87001.1    KQ414618    KOC67941.1    GBGD01001538    JAC87351.1    GEBQ01026803    JAT13174.1    KQ762329    OAD55946.1    GFTR01006163    JAW10263.1   

Proteomes

UP000218220    UP000283053    UP000053240    UP000007151    UP000053268    UP000037510    + More
UP000095300    UP000037069    UP000095301    UP000192221    UP000002282    UP000075883    UP000000803    UP000007801    UP000009192    UP000007798    UP000000304    UP000075920    UP000075885    UP000268350    UP000076408    UP000001292    UP000002320    UP000001819    UP000075900    UP000008711    UP000008744    UP000075881    UP000092553    UP000008820    UP000001070    UP000000673    UP000075882    UP000007062    UP000076407    UP000091820    UP000075840    UP000078200    UP000075901    UP000008792    UP000069272    UP000075902    UP000075880    UP000075884    UP000030765    UP000075903    UP000069940    UP000249989    UP000019118    UP000030742    UP000183832    UP000007266    UP000075886    UP000092462    UP000008237    UP000005203    UP000242457    UP000053097    UP000279307    UP000000311    UP000092444    UP000036403    UP000015102    UP000002358    UP000078541    UP000215335    UP000053105    UP000009046    UP000053825   

PRIDE

Q8MS69   

Pfam

PF04189   Gcd10p        + More
PF01416   PseudoU_synth_1
PF00782   DSPc
PF00595   PDZ
PF07859   Abhydrolase_3
PF03660   PHF5
PF01215   COX5B

Interpro

IPR017423   TRM6        + More
IPR029021   Prot-tyrosine_phosphatase-like       
IPR016130   Tyr_Pase_AS       
IPR020095   PsdUridine_synth_TruA_C       
IPR000387   TYR_PHOSPHATASE_dom       
IPR020103   PsdUridine_synth_cat_dom_sf       
IPR020422   TYR_PHOSPHATASE_DUAL_dom       
IPR000340   Dual-sp_phosphatase_cat-dom       
IPR020097   PsdUridine_synth_TruA_a/b_dom       
IPR036034   PDZ_sf       
IPR029058   AB_hydrolase       
IPR001478   PDZ       
IPR013094   AB_hydrolase_3       
IPR036972   Cyt_c_oxidase_su5b_sf       
IPR005345   PHF5       
IPR002124   Cyt_c_oxidase_su5b       

SUPFAM

SSF55120   SSF55120        + More
SSF52799   SSF52799       
SSF50156   SSF50156       
SSF53474   SSF53474       

Gene 3D

3.30.70.660     3.90.190.10     3.40.50.1820     2.60.11.10    

CDD

cd00127  DSPc
cd00924  Cyt_c_Oxidase_Vb

ProteinModelPortal

A0A2A4K145   A0A3S2LII6   A0A0N1IQ72   S4NT16   A0A212F3X7   A0A194PJP7   + More
A0A0L7LR26   U5ETR0   A0A1I8PC21   A0A1S4JVA7   A0A0L0C434   A0A1Q3EYB9   A0A1I8MWV6   A0A1I8MWV5   A0A1W4UC63   B4P0B8   A0A182M8S7   Q8MS69   B3MNZ2   B4KHU0   B4MUJ5   B4Q4Y4   A0A182W909   A0A182PTD4   A0A034WV42   A0A3B0JIU2   A0A182YMS9   B4HXU1   B0WVR7   A0A0R3NXC8   A0A182RR78   T1DL04   A0A2M4BMB7   B3N5T4   B5DV67   A0A2M4BN74   Q29PC8   B4GKI7   A0A182JTT5   A0A0M4E8P2   W8BEY1   Q17EU7   A0A0K8V879   B4JR99   W5JT56   A0A182KTK2   Q7PMA4   A0A2M4AR62   A0A182XJK6   A0A0A1WPD9   A0A1S4H2E6   A0A1A9W3X5   A0A182HRI4   A0A1A9V5P1   A0A182SAK3   B4LVE5   A0A182F3V8   A0A182UG57   A0A182IMM4   A0A182NAS2   A0A084W8N0   A0A182UUY2   A0A182GSG7   N6TZB4   U4US95   A0A1J1HHH1   D2A3U3   A0A336K501   A0A182Q2J5   A0A1B0DAR7   A0A0A1XTK9   E2BEK2   A0A087ZNU0   A0A2A3EPY7   A0A026WU60   A0A3L8DGQ8   E1ZYD0   A0A1B0G9W0   A0A0J7K997   T1GR17   K7ILS2   A0A1L8DG64   A0A195FUB5   A0A232FJ07   A0A0M8ZZM6   A0A0J7K9R4   A0A1B6HIR9   A0A1B6GEY5   E0VPC2   A0A1B6D8D8   A0A0J7K9T6   A0A0L7RB24   A0A069DUB4   A0A1B6KPM0   A0A310SMI0   A0A224XQ46  

PDB

5CD1     E-value=9.59712e-42,     Score=428

KEGG

101746577    K03256 tRNA (adenine58-N1)-methyltransferase non-catalytic subunit | (RefSeq) tRNA (adenine(58)-N(1)

GO

GO:0030488   GO:0031515   GO:0008168   GO:0005634   GO:0004725   GO:0001522   GO:0009982   GO:0008138   GO:0003723   GO:0016787   GO:0005740   GO:0004129   GO:0015935   GO:0016020   GO:0016817   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

PANTHER

PTHR12945  

Subcellular location

Nucleus  

Length:

384

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06427

Exp number, first 60 AAs:

0

Total prob of N-in:

0.07595

outside

1  -  384

 

 

Pi

209.678222

Theta

186.149408

Tajima's D

0.216685

CLR

11.839034

CSRT

0.435728213589321

Interpretation

Uncertain