Gene

KWMTBOMO08891

Annotation

PREDICTED:_NADPH:adrenodoxin_oxidoreductase?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr15(-):7590186-7593139      View in EpiBrowser

Full name

NADPH:adrenodoxin oxidoreductase, mitochondrial      

Alternative Name

Ferredoxin--NADP(+) reductase

Location in the cell

Cytoplasmic   Reliability : 1.515 Mitochondrial   Reliability : 1.831

CDS

ATGACTTTCGGAAATTTAAGAACTTTGAACAGATTTTATTCAGCAAATAATTACACAAAAATTCCTCGAGTATGTATTGTTGGAGCTGGTCCTGCAGGCTTTTATGCCGCCATGCATCTTACGAAAAACATACAATGCAAGATTGATTTAATAGAAAAACTTCCGGTACCCTTCGGATTAATAAGATATGGTGTAGCTCCAGATCACCCTGAAGTAAAAAATGTGATAAATCAATTTACCAAAGTGGCTCAACGACCAGAGGTCAATTTTTATGGAAATGTTACTCTAGGAAAAGATATCACTTTAAATCAACTAAGACAGCATTATGATGCAGTATTATTGACATATGGTGCTGAAAAAGATAAGACTCTTGGTATAGAAAACGAAAACGCCAAGAATGTTATTGGAGCCAGACATTTTGTTGGATGGTATAATGGGCTACCTAGTAATAAAGACCTGGAGATTGATCTATCTTGTGACACGGCTGCTATTCTTGGTCAAGGCAATGTAGCTCTAGATGTTGCAAGAATACTTTTAAGTCCTATTGATGAACTTAGAAAAACTGATATTACAGAACATGCATTAAATATTCTAGCAGGATCAAAAATCAAACAGTTGTATTTGATTGGTCGAAGAGGTCCACTTCAAGTGGCATTCACTATTAAAGAACTTAGAGAACAATTGAAATTAAGAGATTGTAAGACTGTATGGAGGCCAGAAGATTTTCAAAATGTCATCAATGAAGTTCCTAATTTACCACGCCCTAGAAAAAGAATAACTGAACTCATGCTGAAGTCTTTGAACGAAAATGAAACATGTAGCATCTCTAATAATACAAAAATGTTTAAGCCAATTTTTTTCAGAAGCCCAAAAAAATTCATAATTAACGATAAAAATAATGTAACGGGTATAGAGTTGACTTGTAATAAACTTGAAGGTGAAAATTGGGAGAGTCAAAAGTGTATTCCGACTGATGAAATTGAAGTGGTGAATTGTGGTTTAGTTTTCAGAAGTATCGGATACAAAAGTATCAAAGCAGATGAAGATGTGCCATTTAGTAATGGGCTAGTTTTAAATGAAAGAGGTTGTGTTATTGACGAAGCTAATGAGCTAGGAAAACTGTACGTAGCAGGATGGCTCGGTACTGGACCAGTGGGTGTTATTTTGCACACCATGGGAAATGCATTTCAAGTAGCAAAAACGATTTGTGATGATCTGAAAAACAAAGCTGATTATAGTAAAAGTGGCTTTGCTGAATTCAAAGATATAGTAAAAGACAAGACTGATATAGTTGATTGGGAGGGTTGGCAGAAGATAGATAAGTTTGAAATTGAAGAAGGTAAAAAACGTGGAAAACCACGAGAAAAGATTTGTAGTGTAGAAAAAATTATAGAAATAGCTAAATCAGAATTTAACATTGTTAAGGATAATAGTTAA

Protein

MTFGNLRTLNRFYSANNYTKIPRVCIVGAGPAGFYAAMHLTKNIQCKIDLIEKLPVPFGLIRYGVAPDHPEVKNVINQFTKVAQRPEVNFYGNVTLGKDITLNQLRQHYDAVLLTYGAEKDKTLGIENENAKNVIGARHFVGWYNGLPSNKDLEIDLSCDTAAILGQGNVALDVARILLSPIDELRKTDITEHALNILAGSKIKQLYLIGRRGPLQVAFTIKELREQLKLRDCKTVWRPEDFQNVINEVPNLPRPRKRITELMLKSLNENETCSISNNTKMFKPIFFRSPKKFIINDKNNVTGIELTCNKLEGENWESQKCIPTDEIEVVNCGLVFRSIGYKSIKADEDVPFSNGLVLNERGCVIDEANELGKLYVAGWLGTGPVGVILHTMGNAFQVAKTICDDLKNKADYSKSGFAEFKDIVKDKTDIVDWEGWQKIDKFEIEEGKKRGKPREKICSVEKIIEIAKSEFNIVKDNS

Description

Required for synthesis of steroid hormones, for olfactory sensory behavior and completion of the second larval molt (a steroid mediated developmental transition) and pupariation.

Catalytic Activity

H(+) + NADP(+) + 2 reduced [adrenodoxin] = NADPH + 2 oxidized [adrenodoxin]

Cofactor

FAD

Similarity

Belongs to the ferredoxin--NADP reductase type 1 family.
Belongs to the universal ribosomal protein uS7 family.

Keywords

Complete proteome   Electron transport   FAD   Flavoprotein   Membrane   Mitochondrion   Mitochondrion inner membrane   NADP   Oxidoreductase   Reference proteome   Transit peptide   Transport  

Feature

chain  NADPH:adrenodoxin oxidoreductase, mitochondrial

Uniprot

A0A2A4K1H7   A0A2H1VJW3   A0A0N1PHC9   A0A194PIV5   A0A0L7LR66   A0A212FKT7   + More
A0A0A1XCN3   A0A034W9E0   A0A1A9V0R4   A0A1B0FER1   A0A1A9X3I9   A0A0L0BPB6   A0A3L8E4L9   A0A1A9ZUR3   A0A1I8P8K2   A0A3B0JU50   A0A182MDM5   Q174X5   A0A182QS53   A0A1J1IJV3   A0A1Q3FXU0   A0A1I8MW12   B4MPD7   Q563C8   A0A0L7QLB4   W8ALN6   E2B776   Q28YX8   A0A1B6CMT6   A0A1Y1MNM1   B4KRQ8   A0A1B6KKK1   A0A2M4AMK4   A0A182WLT9   A0A182JV19   A0A182RC28   A0A182NMD3   B4MFM6   A0A084WDB8   A0A1B6FWF6   A0A2J7PXF3   A0A182ISJ6   A0A2M4AMN6   A0A1B6HYA3   A0A023ET68   A0A182GH14   A0A026WD51   W5JN26   A0A182PVJ2   A0A182GH15   A0A182UV01   A0A182HM91   A0A0N0BK36   Q7Q7A2   A0A182Y0R3   A0A182FHP2   Q4U479   B4J8H1   A0A182LJU6   A0A195DZQ4   A0A0K8U3A3   A0A182XCW2   A0A158NER3   A0A195AVM9   A0A0M5IXH9   B4GIJ4   B4QB68   A0A195FM02   C4IY01   Q9V3T9   Q8IGW0   A0A195CRB1   A0A067QIJ6   B4P7H3   B3NSJ6   B4HNE3   A0A1B0GLQ9   V3ZX23   F4WRN3   C3YC80   A0A3Q2YFL0   A0A1W4U5L2   A0A232EI20   E2A158   B3MEU2   E9IAA2   H3ASY8   A0A091TCF0   E6ZGI4   K7FK23   A0A2P4TGP2   A0A093QHD8   A0A1V4KVV0   A0A1W4WWI9   A7RUM6   A0A3Q0G0I8   A0A1D5NXA0   A0A3B3DC21   A0A3B4U2E5   M7B1I9  

EC Number

1.18.1.6

Pubmed

26354079    26227816    22118469    25830018    25348373    26108605    + More
30249741    17510324    25315136    17994087    15804580    24495485    20798317    15632085    28004739    24438588    24945155    26483478    24508170    20920257    23761445    12364791    14747013    17210077    25244985    20966253    21347285    22936249    10498693    10731132    12537572    24845553    17550304    23254933    21719571    18563158    28648823    21282665    9215903    17381049    17615350    15592404    29451363    23624526   

EMBL

NWSH01000302    PCG77613.1    ODYU01002957    SOQ41115.1    KQ459937    KPJ19209.1    + More
KQ459602    KPI93252.1    JTDY01000275    KOB77952.1    AGBW02007963    OWR54361.1    GBXI01005580    JAD08712.1    GAKP01008222    JAC50730.1    CCAG010009035    JRES01001578    KNC21828.1    QOIP01000001    RLU27365.1    OUUW01000001    SPP74598.1    AXCM01007726    CH477404    EAT41657.1    AXCN02000934    CVRI01000054    CRL00472.1    GFDL01002753    JAV32292.1    CH963849    EDW73976.1    AY947548    AAX85204.1    KQ414924    KOC59395.1    GAMC01016905    JAB89650.1    GL446149    EFN88437.1    CM000071    EAL25838.1    GEDC01022514    JAS14784.1    GEZM01026070    JAV87261.1    CH933808    EDW08328.1    GEBQ01027998    JAT11979.1    GGFK01008688    MBW42009.1    CH940667    EDW57197.2    ATLV01022985    KE525339    KFB48212.1    GECZ01015318    JAS54451.1    NEVH01020859    PNF20994.1    GGFK01008719    MBW42040.1    GECU01037318    GECU01028057    JAS70388.1    JAS79649.1    GAPW01001115    JAC12483.1    JXUM01062870    KQ562219    KXJ76369.1    KK107260    EZA54000.1    ADMH02001054    ETN64295.1    KXJ76370.1    APCN01004380    KQ435709    KOX80011.1    AAAB01008960    EAA11924.4    DQ013245    AAY34441.1    CH916367    EDW02330.1    KQ979999    KYN18311.1    GDHF01031127    GDHF01006350    JAI21187.1    JAI45964.1    ADTU01013612    KQ976736    KYM76117.1    CP012524    ALC41486.1    CH479183    EDW36314.1    CM000362    CM002911    EDX06601.1    KMY92958.1    KQ981490    KYN41282.1    BT083432    ACQ99837.1    AF168685    AE013599    BT001566    AAN71321.1    KQ977381    KYN03175.1    KK853521    KDR07014.1    CM000158    EDW90008.1    CH954179    EDV56498.1    CH480816    EDW47379.1    AJWK01032941    KB202953    ESO87175.1    GL888292    EGI63040.1    GG666500    EEN62112.1    NNAY01004368    OXU17995.1    GL435707    EFN72825.1    CH902619    EDV35556.1    GL761997    EFZ22498.1    AFYH01091804    AFYH01091805    KK469277    KFQ56531.1    FQ310507    CBN81168.1    AGCU01174015    AGCU01174016    AGCU01174017    AGCU01174018    PPHD01000408    POI35519.1    KL671685    KFW83482.1    LSYS01001520    OPJ88629.1    DS469540    EDO44879.1    AADN05000628    KB547685    EMP30904.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000037510    UP000007151    UP000078200    + More
UP000092444    UP000091820    UP000037069    UP000279307    UP000092445    UP000095300    UP000268350    UP000075883    UP000008820    UP000075886    UP000183832    UP000095301    UP000007798    UP000053825    UP000008237    UP000001819    UP000009192    UP000075920    UP000075881    UP000075900    UP000075884    UP000008792    UP000030765    UP000235965    UP000075880    UP000069940    UP000249989    UP000053097    UP000000673    UP000075885    UP000075903    UP000075840    UP000053105    UP000007062    UP000076408    UP000069272    UP000001070    UP000075882    UP000078492    UP000076407    UP000005205    UP000078540    UP000092553    UP000008744    UP000000304    UP000078541    UP000000803    UP000078542    UP000027135    UP000002282    UP000008711    UP000001292    UP000092461    UP000030746    UP000007755    UP000001554    UP000264820    UP000192221    UP000215335    UP000000311    UP000007801    UP000008672    UP000007267    UP000053258    UP000190648    UP000192223    UP000001593    UP000189705    UP000000539    UP000261560    UP000261420    UP000031443   

PRIDE

C4IY01    Q9V3T9    Q8IGW0   

Pfam

PF07992   Pyr_redox_2        + More
PF16178   Anoct_dimer
PF00177   Ribosomal_S7
PF01728   FtsJ
PF05030   SSXT

Interpro

IPR021163   Ferredox_Rdtase_adrenod        + More
IPR036188   FAD/NAD-bd_sf       
IPR023753   FAD/NAD-binding_dom       
IPR032394   Anoct_dimer       
IPR036823   Ribosomal_S7_dom_sf       
IPR020606   Ribosomal_S7_CS       
IPR005716   Ribosomal_S5/S7_euk/arc       
IPR000235   Ribosomal_S5/S7       
IPR023798   Ribosomal_S7_dom       
IPR029063   SAM-dependent_MTases       
IPR025807   Adrift-typ_MeTrfase       
IPR002877   rRNA_MeTrfase_FtsJ_dom       
IPR007726   SS18_fam       

SUPFAM

SSF51905   SSF51905        + More
SSF47973   SSF47973       
SSF53335   SSF53335       

Gene 3D

3.50.50.60     1.10.455.10    

CDD

cd14867  uS7_Eukaryote

ProteinModelPortal

A0A2A4K1H7   A0A2H1VJW3   A0A0N1PHC9   A0A194PIV5   A0A0L7LR66   A0A212FKT7   + More
A0A0A1XCN3   A0A034W9E0   A0A1A9V0R4   A0A1B0FER1   A0A1A9X3I9   A0A0L0BPB6   A0A3L8E4L9   A0A1A9ZUR3   A0A1I8P8K2   A0A3B0JU50   A0A182MDM5   Q174X5   A0A182QS53   A0A1J1IJV3   A0A1Q3FXU0   A0A1I8MW12   B4MPD7   Q563C8   A0A0L7QLB4   W8ALN6   E2B776   Q28YX8   A0A1B6CMT6   A0A1Y1MNM1   B4KRQ8   A0A1B6KKK1   A0A2M4AMK4   A0A182WLT9   A0A182JV19   A0A182RC28   A0A182NMD3   B4MFM6   A0A084WDB8   A0A1B6FWF6   A0A2J7PXF3   A0A182ISJ6   A0A2M4AMN6   A0A1B6HYA3   A0A023ET68   A0A182GH14   A0A026WD51   W5JN26   A0A182PVJ2   A0A182GH15   A0A182UV01   A0A182HM91   A0A0N0BK36   Q7Q7A2   A0A182Y0R3   A0A182FHP2   Q4U479   B4J8H1   A0A182LJU6   A0A195DZQ4   A0A0K8U3A3   A0A182XCW2   A0A158NER3   A0A195AVM9   A0A0M5IXH9   B4GIJ4   B4QB68   A0A195FM02   C4IY01   Q9V3T9   Q8IGW0   A0A195CRB1   A0A067QIJ6   B4P7H3   B3NSJ6   B4HNE3   A0A1B0GLQ9   V3ZX23   F4WRN3   C3YC80   A0A3Q2YFL0   A0A1W4U5L2   A0A232EI20   E2A158   B3MEU2   E9IAA2   H3ASY8   A0A091TCF0   E6ZGI4   K7FK23   A0A2P4TGP2   A0A093QHD8   A0A1V4KVV0   A0A1W4WWI9   A7RUM6   A0A3Q0G0I8   A0A1D5NXA0   A0A3B3DC21   A0A3B4U2E5   M7B1I9  

PDB

1E6E     E-value=7.71476e-104,     Score=964

KEGG

101736047    K18914 adrenodoxin-NADP+ reductase [EC:1.18.1.6] | (RefSeq) NADPH:adrenodoxin oxidoreductase, mitoch

GO

GO:0015039   GO:0005739   GO:0046983   GO:0005840   GO:0003735   GO:0006412   GO:0003723   GO:0015935   GO:0042048   GO:0035073   GO:0007591   GO:0007552   GO:0006694   GO:0008168   GO:0016491   GO:0006744   GO:0003713   GO:0006707   GO:0009055   GO:0005759   GO:0005743   GO:0006886   GO:0016192   GO:0030131   GO:0016020   GO:0016817   GO:0008270   GO:0043565   GO:0016876   GO:0043039   GO:0055114  

PANTHER

PTHR11205  

Subcellular location

Mitochondrion  
Mitochondrion inner membrane  

Length:

478

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

10.18481

Exp number, first 60 AAs:

9.59964999999999

Total prob of N-in:

0.49501

outside

1  -  478

 

 

Pi

269.555344

Theta

199.661761

Tajima's D

1.101864

CLR

0

CSRT

0.690665466726664

Interpretation

Uncertain