Gene

KWMTBOMO08877

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr15(+):7028027-7029142      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.736

CDS

ATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCATCGGATGCGTTACCACCCGTCACCCCGATAGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACTGTATATCTAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCTATAAAAACACAACTATATTCTGTGTACAGCAGTCTGGCTTAACACGTGTCCCTAGTGAGCTAGTTTTGTTACATCTGAAAAGTTGTTTAGGGCGACTTAGAGAGGTTCAGTTAGGCGAGTATGTAATCACGAGTTTAACGGTGTTAGAAATTCTCAGGTTCATTAAATTATAA

Protein

MRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPIEVKDLIKDLRPRKAPGSDCISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLYKNTTIFCVQQSGLTRVPSELVLLHLKSCLGRLREVQLGEYVITSLTVLEILRFIKL

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   D7EM17   + More
A0A139W8G9   A0A1Y1NA23   A0A139WA11   A0A2S2Q352   A0A1B6J5Z9   A0A2S2NPT6   U4U0U7   V5GNJ2   J9KLB1   A0A2H8U0H5   A0A023F6S4   A0A2S2PEZ9   A0A2S2QEE0   A0A0C9RJA4   V5GNF3   X1WVL6   A0A224X6S1   A0A087UDC5   K7IN67   X1WKS2   A0A2S2PA10   A0A2S2N6C8   A0A087UCW3   A0A2S2N629   A0A3N5Z7I3   A0A2J7R7D0   A0A2S2NCK2   A0A1Y1K0C8   A0A1Y1LKN6   A0A224X6U5   A0A224X7Z3   Q95SX7   A0A1Y1KFT3   A0A2J7Q0S7   A0A2S2N814   A0A224XI99   A0A1Y1KFR3   A0A2S2PWA8   A0A2S2Q5V3   J9K7I4   A0A1B6C2V8   A0A023F700   A0A2S2PPK8   A0A2S2RB48   A0A2H8TKI9   A0A2S2NH02   A0A023F754   A0A2S2QLY2   A0A2S2PBB4   Q07995   A0A2S2PR14   A0A069DZC5   A0A069DW01   J9KKL3   A0A1Y1MHM1   A0A224X6T4   A0A087UB64   A0A069DVA6   A0A023F069   A0A2S2R9D4   A0A2S2P3X8   A0A224X6W2   A0A023EYS8   A0A224X724  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    18362917    19820115    28004739    + More
23537049    25474469    20075255    30086797    7753626    12537569    8387152    26334808   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    KQ973412    EFA12510.2    KQ973342    KXZ75569.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    GGMS01002955    MBY72158.1    GECU01013097    JAS94609.1    GGMR01006581    MBY19200.1    KB631961    ERL87484.1    GALX01005299    JAB63167.1    ABLF02040174    ABLF02040183    ABLF02055266    GFXV01007093    MBW18898.1    GBBI01001646    JAC17066.1    GGMR01015412    MBY28031.1    GGMS01006359    MBY75562.1    GBYB01008290    JAG78057.1    GALX01005359    JAB63107.1    ABLF02042385    GFTR01008271    JAW08155.1    KK119316    KFM75364.1    ABLF02005245    ABLF02013477    ABLF02047385    ABLF02066435    GGMR01013409    MBY26028.1    GGMR01000086    MBY12705.1    KK119261    KFM75202.1    GGMR01000005    MBY12624.1    RPOV01000134    RPJ78669.1    NEVH01006736    PNF36716.1    GGMR01002322    MBY14941.1    GEZM01099921    GEZM01099920    GEZM01099918    GEZM01099906    JAV53125.1    GEZM01053022    JAV74219.1    GFTR01008251    JAW08175.1    GFTR01007929    JAW08497.1    AY060438    AAL25477.1    GEZM01084970    JAV60359.1    NEVH01019963    PNF22185.1    GGMR01000676    MBY13295.1    GFTR01008256    JAW08170.1    GEZM01084969    JAV60363.1    GGMS01000625    MBY69828.1    GGMS01003914    MBY73117.1    ABLF02017543    ABLF02017549    ABLF02017551    ABLF02021996    GEDC01029594    JAS07704.1    GBBI01001699    JAC17013.1    GGMR01018716    MBY31335.1    GGMS01018022    MBY87225.1    GFXV01002840    MBW14645.1    GGMR01003864    MBY16483.1    GBBI01001642    JAC17070.1    GGMS01009480    MBY78683.1    GGMR01014053    MBY26672.1    S59870    AAB26437.2    GGMR01019198    MBY31817.1    GBGD01000880    JAC88009.1    GBGD01000799    JAC88090.1    ABLF02029306    ABLF02029314    ABLF02060138    GEZM01032972    JAV84478.1    GFTR01008261    JAW08165.1    KK119069    KFM74603.1    GBGD01000881    JAC88008.1    GBBI01003810    JAC14902.1    GGMS01017365    MBY86568.1    GGMR01011511    MBY24130.1    GFTR01008260    JAW08166.1    GBBI01004395    JAC14317.1    GFTR01008169    JAW08257.1   

Proteomes

UP000053268    UP000007266    UP000030742    UP000007819    UP000054359    UP000002358    + More
UP000235965   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2
PF03564   DUF1759
PF18701   DUF5641
PF00665   rve
PF05380   Peptidase_A17
PF17921   Integrase_H2C2
PF05585   DUF1758

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       
IPR041588   Integrase_H2C2       
IPR036397   RNaseH_sf       
IPR005312   DUF1759       
IPR040676   DUF5641       
IPR008737   Peptidase_asp_put       
IPR008042   Retrotrans_Pao       
IPR012337   RNaseH-like_sf       
IPR001584   Integrase_cat-core       

SUPFAM

SSF56219   SSF56219        + More
SSF53098   SSF53098       

Gene 3D

3.60.10.10     3.30.420.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   D7EM17   + More
A0A139W8G9   A0A1Y1NA23   A0A139WA11   A0A2S2Q352   A0A1B6J5Z9   A0A2S2NPT6   U4U0U7   V5GNJ2   J9KLB1   A0A2H8U0H5   A0A023F6S4   A0A2S2PEZ9   A0A2S2QEE0   A0A0C9RJA4   V5GNF3   X1WVL6   A0A224X6S1   A0A087UDC5   K7IN67   X1WKS2   A0A2S2PA10   A0A2S2N6C8   A0A087UCW3   A0A2S2N629   A0A3N5Z7I3   A0A2J7R7D0   A0A2S2NCK2   A0A1Y1K0C8   A0A1Y1LKN6   A0A224X6U5   A0A224X7Z3   Q95SX7   A0A1Y1KFT3   A0A2J7Q0S7   A0A2S2N814   A0A224XI99   A0A1Y1KFR3   A0A2S2PWA8   A0A2S2Q5V3   J9K7I4   A0A1B6C2V8   A0A023F700   A0A2S2PPK8   A0A2S2RB48   A0A2H8TKI9   A0A2S2NH02   A0A023F754   A0A2S2QLY2   A0A2S2PBB4   Q07995   A0A2S2PR14   A0A069DZC5   A0A069DW01   J9KKL3   A0A1Y1MHM1   A0A224X6T4   A0A087UB64   A0A069DVA6   A0A023F069   A0A2S2R9D4   A0A2S2P3X8   A0A224X6W2   A0A023EYS8   A0A224X724  

KEGG

105842617    no KO assigned | (RefSeq) uncharacterized LOC105842617

GO

GO:0003964   GO:0004519   GO:0006313   GO:0016021   GO:0003676   GO:0015074  

Length:

298

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

12.62355

Exp number, first 60 AAs:

0.00861

Total prob of N-in:

0.44974

outside

1  -  298

 

 

Pi

6.859009

Theta

9.017322

Tajima's D

-0.697483

CLR

0.042144

CSRT

0.19974001299935

Interpretation

Uncertain