Gene

KWMTBOMO08875

Pre Gene Modal

BGIBMGA007837

Annotation

PREDICTED:_gamma-aminobutyric_acid_type_B_receptor_subunit_1_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr15(-):6954708-7000276      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 3.896

CDS

ATGTTTCTGCTATGGTTGAGCGCTTGTGGGGGCTATAGTGAAGGAAGACGCGACAATGACCTGCATATCGGCGGCATTTTCCCTATGGAGGGTGAAGGTGGCTGGCAGGGAGGACAAGCGTGTATGCCAGCCGCAGAACTCGCGCTTGCCGACGTGAATGCCAGATCGGACCTATTATCCGGATTTAAGCTACGTCTGCACAGCAACGACAGCAAGTGCGAACCAGGGTTGGGAGCCAGCGTCATGTACAATTTACTGTATAACCCACCGCAAAAATTGTTGCTGCTAGCAGGATGTTCGACAGTTTGTACTACAGTCGCGGAAGCTGCTAAGATGTGGAACCTAATGGTCTTGTGCTATGGAGCTTCGTCGCCAGCGCTGTCGGATCGGTCTCGTTTCCCGACGTTATTCCGAACGCACCCGTCAGCAACAGTCCACAACCCGACGAGAATCAAGCTGATGCAGAAGTTCGCCTGGTCACGAATCGCTATACTGCAACAGGCCGAGGAAGTTTTTATTTCGACTGTCGAAGATTTGGAGGCTCACTGCAAGAAGGCCGGGATCGAAATCGTAACCCGCCAATCGTTTCTATCAGACCCAGCAGACGCCGTGAGGAATCTTCGTCGTCAAGATGCGAGAGTGATCGTCGGCCTGTTCTACGTAGTAGCAGCCAGGAGAGTACTCTGTGAAGTATACAAGCATAGACTATACGGAAAATCCTACGTGTGGTTCTTTATAGGTTGGTATGAGGATAATTGGTTCGAGACGAATCTAGAACGGGAAGGCATCGAATGCACGGTGGAACAGATGAGAGAAGCGGCCGAAGGTCACCTCACAACCGAAGCTCTAATGTGGAATCAAAATGCCAACCAAACTACGATATCCGGAATGACATCTGAAGATTTTAGGTCAAGATTAAATGAGGCACTCCGCGAAGCTGGCTACGACATCGATGGAGAACGGTATCCGGAAGGCTACCAAGAGGCACCCTTGGCTTATGATGCAGTCTGGTCTGTTGCTCTGGCTTTCAATAAAACAATGGAGAAACTGCAGAAGAGCGGTTTGAGTTTGAAGAATTTCACGTACACAAACAAGAAAATAGCTGATGACATTTACGAAGCCATAAATTCGACGTCGTTCCTTGGTGTTTCGGGATTGGTAGCATTTTCGTCTCAAGGTGATCGCATAGCTCTGACACAAATCGAACAATTAACAGACAATCATTACGTGAAACTTGGATATTATGATACACAAGCAGACAACCTTACTTGGCTAGATCGGGAACGGTGGGTCGGTGGAAAAGTCCCTCCCGATCGAACTGTGGTCGTCAATGAGCTGCGAACGGTTTCTCTGCCGCTTTTCGCGTGTATGACGGCCCTCTGCATCGCTGGAATATTGGCAGCCATAGCTCTTATCGTATTTAATATAATGCATAGACACAGAAGAGTAATACAATGGTCCCACCCGGCTTGCAACACCGTAATGCTTTGTGGATGCTGCGTGTGTCTCTGTGCGGCAGTAGCTTTGGGCGTCGATGGGCGATGGGTACTACCTCAACACTTCAATGGATTGTGCGCTGCCCGAGCTTGGCTCTTGGCTACAGGATTCTCGATGGCATATGGAGCAATGTTTACGAAAGTCTGGAGGGTACATCGACATACGACTAAACCAAAAATTGATAATAAGAAACGCATTCATGGTTGGAAACTGTATACAATGGTCGGGGGACTGCTCGTTGTAGACGTTGCACTCCTGACAGCTTGGCAGCTCCGGGACCCGCTGCAGCGACGCGTCGAGACATTCCCCCTGGAAGCCCCGCGACATCACGACGACGACGTGCACATACGACCCGAATTGGAACACTGTGAGAGCAAACATAACACCGTGTGGCTTGGCGTAATGTACGGGTACAAAGGCCTGGTGCTAGTTTTCGGACTGTTCCTGGCCTACGAGACACGCTCGGTGAAGGTTCGACAGATTAATGACTCTCGCTACGTCGGCATGAGCATATACAACGTGGTCGTGTTGTGCCTTATCACTGCGCCGGTTACGTTGGTCATTGCGAGTCAACAAGACGCAGCGTTCGCCTTCGTTTCCCTAGCGATTGTCTTCTGTTGCTTCCTGAGTATGGCCCTAATATTCGTACCTAAGGTAATAGAAGTGATTCGTCATCCAACCGAGCGCGTGGAGAGCGGTCGAGGGTCTGGTTCCGGCTCCGCGCCGGCCGACGAGGAACGCTACCGGGAACTAGTCAAAGAAAATGAAGAATTACAAAAATTAATTACACAAGTACGTACGCTTATGAACGAACTAATAACACGGGCGTTACCGGTCTTCTATATCTTTGTACTCTAA

Protein

MFLLWLSACGGYSEGRRDNDLHIGGIFPMEGEGGWQGGQACMPAAELALADVNARSDLLSGFKLRLHSNDSKCEPGLGASVMYNLLYNPPQKLLLLAGCSTVCTTVAEAAKMWNLMVLCYGASSPALSDRSRFPTLFRTHPSATVHNPTRIKLMQKFAWSRIAILQQAEEVFISTVEDLEAHCKKAGIEIVTRQSFLSDPADAVRNLRRQDARVIVGLFYVVAARRVLCEVYKHRLYGKSYVWFFIGWYEDNWFETNLEREGIECTVEQMREAAEGHLTTEALMWNQNANQTTISGMTSEDFRSRLNEALREAGYDIDGERYPEGYQEAPLAYDAVWSVALAFNKTMEKLQKSGLSLKNFTYTNKKIADDIYEAINSTSFLGVSGLVAFSSQGDRIALTQIEQLTDNHYVKLGYYDTQADNLTWLDRERWVGGKVPPDRTVVVNELRTVSLPLFACMTALCIAGILAAIALIVFNIMHRHRRVIQWSHPACNTVMLCGCCVCLCAAVALGVDGRWVLPQHFNGLCAARAWLLATGFSMAYGAMFTKVWRVHRHTTKPKIDNKKRIHGWKLYTMVGGLLVVDVALLTAWQLRDPLQRRVETFPLEAPRHHDDDVHIRPELEHCESKHNTVWLGVMYGYKGLVLVFGLFLAYETRSVKVRQINDSRYVGMSIYNVVVLCLITAPVTLVIASQQDAAFAFVSLAIVFCCFLSMALIFVPKVIEVIRHPTERVESGRGSGSGSAPADEERYRELVKENEELQKLITQVRTLMNELITRALPVFYIFVL

Similarity

Belongs to the G-protein coupled receptor 3 family.

Uniprot

H9JE90   A0A3S2M9U9   S6DR08   A0A2H1WAC6   A0A194RD58   A0A2A4JSW0   + More
A0A194PQ25   A0A310SM81   B3MLC7   A0A0L0BVC8   B4JAW8   A0A0L7R583   A0A0R1DST3   A0A0R1DQW3   A0A0R1DSQ2   Q9V3Q9   B4P0X4   B4MZ77   A0A0R1DLG3   B3N5N0   B4LRY4   B4KLC2   A0A0Q5WMT4   W8BH72   A0A3B0KBC3   A0A0R3NQZ1   A0A0Q5WIS6   A0A1W4W038   Q29P68   Q9BML7   A0A0Q5W991   B4HXL4   A0A1S4H3I9   A0A182I0W8   T1I7D6   A0A182KJX6   A0A0J9R2J4   A0A182YN14   A0A182PPU0   A0A182JP69   A0A182Q9X6   A0A182N8X1   V6DNG0   Q7PME5   A0A182RAF4   A0A1B0CTX3   K7IRD3   A0A2J7Q0I1   W5JI42   A0A182F8W2   A0A088ACG8   A0A084W5M4   A0A2A3EH29   A0A026WP30   A0A232F0L8   A0A3L8E2F5   E1ZXC0   A0A195BEF8   A0A158NQP1   A0A151XB41   F4WBW8   A0A182VSS1   A0A182MVL9   A0A0K8TG24   E0VWF6   A0A195FSC0   A0A0M9AA59   A0A1B6IMJ1   A0A067RJX4   A0A1I8MUN8   E2BM97   B4GK77   B4Q5Y9   A0A1J1IUN2   A0A1S4FG88   A0A195D3M2   A0A2H8TER2   A0A1I8PIE9   E9J436   A0A1Y1LWI4   A0A1J0FAU9   A0A182V1I8   A0A182U5X5   A0A182XCP2   A0A1J0FAT2   A0A1D2NC33   A0A226E705   A0A0P5LWC8   A0A0P6GYC0   A0A182J9B7   A0A0P5TKA2   A0A0P5BNQ1   A0A0P6C3F4   E9G2I1   N6UCG3   A0A061QLL2   A0A1E1X357   H9B3X8   A0A2L2Y1Y5   A0A147BN21  

Pubmed

19121390    26354079    17994087    26108605    17550304    10731132    + More
12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24495485    15632085    11168554    12364791    20966253    22936249    25244985    20075255    20920257    23761445    24438588    24508170    28648823    30249741    20798317    21347285    21719571    20566863    24845553    25315136    17510324    21282665    28004739    27289101    21292972    23537049    28503490    22403662    26561354    29652888   

EMBL

BABH01002757    BABH01002758    BABH01002759    BABH01002760    RSAL01000005    RVE54351.1    + More
HG004164    CDF56917.1    ODYU01007216    SOQ49802.1    KQ460367    KPJ15547.1    NWSH01000638    PCG75101.1    KQ459602    KPI93235.1    KQ759886    OAD62141.1    CH902620    EDV30716.1    JRES01001277    KNC24020.1    CH916368    EDW02838.1    KQ414654    KOC66008.1    CM000157    KRJ98145.1    KRJ98146.1    KRJ98144.1    AE014134    BT031099    AAF53431.3    ABX00721.1    AFH03707.1    EDW89048.2    CH963913    EDW77473.2    KRJ98143.1    KRJ98147.1    CH954177    EDV57989.2    CH940649    EDW63660.2    CH933807    EDW11783.2    KQS70216.1    GAMC01010222    GAMC01010221    JAB96333.1    OUUW01000046    SPP90012.1    CH379058    KRT03495.1    KQS70217.1    EAL34425.2    AF318272    AAK13420.1    KQS70215.1    CH480818    EDW51794.1    AAAB01008980    APCN01005282    ACPB03006256    CM002910    KMY90316.1    AXCN02001871    HG794357    CDK37791.1    EAA13942.4    AJWK01028079    AJWK01028080    NEVH01019967    PNF22098.1    ADMH02001341    ETN62953.1    ATLV01020674    KE525304    KFB45518.1    KZ288256    PBC30592.1    KK107154    EZA56859.1    NNAY01001402    OXU24099.1    QOIP01000001    RLU26555.1    GL435030    EFN74210.1    KQ976511    KYM82550.1    ADTU01023455    KQ982335    KYQ57564.1    GL888066    EGI68396.1    AXCM01000163    GBRD01001460    GBRD01001459    JAG64361.1    DS235819    EEB17707.1    KQ981280    KYN43485.1    KQ435702    KOX80340.1    GECU01019577    JAS88129.1    KK852463    KDR23323.1    GL449158    EFN83223.1    CH479184    EDW37043.1    CM000361    EDX05092.1    CVRI01000058    CRL02846.1    KQ976885    KYN07498.1    GFXV01000766    MBW12571.1    GL768069    EFZ12431.1    GEZM01047923    JAV76690.1    KU986874    APC26103.1    KU986868    APC26097.1    LJIJ01000095    ODN02817.1    LNIX01000007    OXA52376.1    GDIQ01177444    GDIQ01173250    GDIQ01166409    GDIQ01162156    GDIP01044550    LRGB01000996    JAK78475.1    JAM59165.1    KZS14238.1    GDIQ01027552    JAN67185.1    GDIP01125131    JAL78583.1    GDIP01182023    JAJ41379.1    GDIP01009869    JAM93846.1    GL732530    EFX86255.1    APGK01040537    APGK01040538    APGK01040539    APGK01040540    APGK01040541    APGK01040542    KB740983    ENN76342.1    GBFC01000039    JAC59299.1    GFAC01005516    JAT93672.1    JN974907    AFC88976.1    IAAA01002824    LAA02196.1    GEGO01003217    JAR92187.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000218220    UP000053268    UP000007801    + More
UP000037069    UP000001070    UP000053825    UP000002282    UP000000803    UP000007798    UP000008711    UP000008792    UP000009192    UP000268350    UP000001819    UP000192221    UP000001292    UP000075840    UP000015103    UP000075882    UP000076408    UP000075885    UP000075881    UP000075886    UP000075884    UP000007062    UP000075900    UP000092461    UP000002358    UP000235965    UP000000673    UP000069272    UP000005203    UP000030765    UP000242457    UP000053097    UP000215335    UP000279307    UP000000311    UP000078540    UP000005205    UP000075809    UP000007755    UP000075920    UP000075883    UP000009046    UP000078541    UP000053105    UP000027135    UP000095301    UP000008237    UP000008744    UP000000304    UP000183832    UP000078542    UP000095300    UP000075903    UP000075902    UP000076407    UP000094527    UP000198287    UP000076858    UP000075880    UP000000305    UP000019118   

PRIDE

H9JE90    Q9V3Q9    Q9BML7   

Pfam

PF00003   7tm_3        + More
PF01094   ANF_receptor
PF14846   DUF4485

Interpro

IPR028082   Peripla_BP_I        + More
IPR002455   GPCR3_GABA-B       
IPR002456   GPCR_3_GABA_rcpt_B1       
IPR001828   ANF_lig-bd_rcpt       
IPR017978   GPCR_3_C       
IPR000337   GPCR_3       
IPR029063   SAM-dependent_MTases       
IPR027831   DUF4485       

SUPFAM

SSF53822   SSF53822        + More
SSF53335   SSF53335       

CDD

cd15291  7tmC_GABA-B-R1

ProteinModelPortal

H9JE90   A0A3S2M9U9   S6DR08   A0A2H1WAC6   A0A194RD58   A0A2A4JSW0   + More
A0A194PQ25   A0A310SM81   B3MLC7   A0A0L0BVC8   B4JAW8   A0A0L7R583   A0A0R1DST3   A0A0R1DQW3   A0A0R1DSQ2   Q9V3Q9   B4P0X4   B4MZ77   A0A0R1DLG3   B3N5N0   B4LRY4   B4KLC2   A0A0Q5WMT4   W8BH72   A0A3B0KBC3   A0A0R3NQZ1   A0A0Q5WIS6   A0A1W4W038   Q29P68   Q9BML7   A0A0Q5W991   B4HXL4   A0A1S4H3I9   A0A182I0W8   T1I7D6   A0A182KJX6   A0A0J9R2J4   A0A182YN14   A0A182PPU0   A0A182JP69   A0A182Q9X6   A0A182N8X1   V6DNG0   Q7PME5   A0A182RAF4   A0A1B0CTX3   K7IRD3   A0A2J7Q0I1   W5JI42   A0A182F8W2   A0A088ACG8   A0A084W5M4   A0A2A3EH29   A0A026WP30   A0A232F0L8   A0A3L8E2F5   E1ZXC0   A0A195BEF8   A0A158NQP1   A0A151XB41   F4WBW8   A0A182VSS1   A0A182MVL9   A0A0K8TG24   E0VWF6   A0A195FSC0   A0A0M9AA59   A0A1B6IMJ1   A0A067RJX4   A0A1I8MUN8   E2BM97   B4GK77   B4Q5Y9   A0A1J1IUN2   A0A1S4FG88   A0A195D3M2   A0A2H8TER2   A0A1I8PIE9   E9J436   A0A1Y1LWI4   A0A1J0FAU9   A0A182V1I8   A0A182U5X5   A0A182XCP2   A0A1J0FAT2   A0A1D2NC33   A0A226E705   A0A0P5LWC8   A0A0P6GYC0   A0A182J9B7   A0A0P5TKA2   A0A0P5BNQ1   A0A0P6C3F4   E9G2I1   N6UCG3   A0A061QLL2   A0A1E1X357   H9B3X8   A0A2L2Y1Y5   A0A147BN21  

PDB

4MS4     E-value=5.64706e-133,     Score=1218

KEGG

101735335    K04615 gamma-aminobutyric acid type B receptor | (RefSeq) gamma-aminobutyric acid type B receptor su

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0004965   GO:0007214   GO:0046982   GO:0007193   GO:0038039   GO:0007186   GO:0005887   GO:0004930   GO:0016020   GO:0016817   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

PANTHER

PTHR10519  

SignalP

Position:   1 - 15,         Likelihood:  0.588624

 

 

Length:

784

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

154.7048

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00117

outside

1  -  453

TMhelix

454  -  476

inside

477  -  488

TMhelix

489  -  511

outside

512  -  525

TMhelix

526  -  548

inside

549  -  567

TMhelix

568  -  590

outside

591  -  627

TMhelix

628  -  650

inside

651  -  669

TMhelix

670  -  689

outside

690  -  692

TMhelix

693  -  715

inside

716  -  784

 

 

Pi

198.405967

Theta

160.173953

Tajima's D

0.519635

CLR

0.523656

CSRT

0.52002399880006

Interpretation

Uncertain