Gene

KWMTBOMO08865  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007842

Annotation

PREDICTED:_protein_arginine_N-methyltransferase_5_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(-):6739662-6747815      View in EpiBrowser

Full name

Protein arginine N-methyltransferase       + More
Protein arginine N-methyltransferase 5      

Location in the cell

Nuclear   Reliability : 1.185

CDS

ATGGCACAGCAAGAAATATCTTGTGGTTATGAATACATAATAACTGCTGATTTACAAACATGTCTCACAGAAGCACTTCAATGCAGTTATTCATTTATAGTTTCGCCCATTATTCACCCACGTTTTCGTAGGCAATCCACAAATGCCGGTAAAAATGGTGGTTTTACGCGGTCAGATATGGTTCTATCACCTCAAGATTGGACTAGCAGGATAGTAGCTAAGCTATCTCCGTACATTAACGTTGATTCACCTTCAGCGACTGTTAGGCAGCGTCACGAGGATTATTTGAATGAGGAACTATCATACTGTAGGGGACTTGGTGTGCCTGCAATCATGATATCAATACACGGGAGAGAGAGCAACAATTTAGCCAGAATTCTCCAAACTTATTATGAAACGAGCCACCATCCGTCTCTAATATGGGCATGTGTACCTATGCTATGTAGTAGAACATATAGAGAATGCACTGAAGATGATGAAGAAGAGAAAGCTTGGAATGAGCCCTGGTACTGGTGGTCCAAATTCCATGAGCGCCTTGATTGGGATAAACGTGTTGGTGTTGTTTTGGAGTTGTCTGCAGATCTTCCATCACAGGAAGTAGTAAAGAGATGGCTTGGTGAACCAGTAAAAGCGATTATCGTACCAACATCAATATTTCATAATAACAAAAAAGGATATCCTGTTTTGTCTCGGGCTCACCAACAACTTGTAGTTAGCATGGTAGAACATGAAGCACAGGTTATAGTTAGTGGTGCTCGAAGATCCAACATTGAATTCTTCGTACAGTATCTACACCGGGTGTGGAGAAGAAGGCCAAATCCAGCAAATGATCCTATGCTCAGCTATGCAAGAGGATGGGAAGACTACCTACAAACACCACTGCAGCCCCTAGCAGATAATTTAGATACACACACATATAATGTATTTGAAAAGGATCCAGTTAAATATAATCAATATCAAAAAGCTATTGCACAGGCGTTGATTGATGTACAGAAGGACCGGGCTGTGAAACAGATTGCTGAATATTTTCAGAGCAAAGCGAGCTGTAATGTAGCATCTATCAACCAATGTTCAAAAAATGAATTATGCGACAACAATACGAAAGAGTTGATTAGAGATGATCCTATAACTGTAATGGTACTTGGTGCGGGCCGGGGACCCCTAGTGAGAGCCACATTCAATGCTTCCGATATAACAAATACCAAAGTTAAGGTAATTGCCGTTGAGAAGAATCCATGTGCTGTAGTAGTGTTAGCTGCACAGGTACGAGAAGTCTGGCGTAATCGTGATGTGGTTGTTATACCTGGGGATATGAGGCAAATAAACTTGTCACCCAAAGCTGATATTATAGTTTCTGAATTGTTAGGTTCTTGGGGAGATAATGAGCTTTCGCCTGAATGCTTGGATGGAGCATCGAATCTTTTAAAACCCGGCGGAATATCGATTCCAAGCTCATATCGATCGTATGTTGCACCCATAACGTCTCCCAGGTTATGGGCTGCCGCGAAAATAGCAACTTCAGGAATTCCCCAACAAAAAGATAAGAACCTCGAAACATTATGGGTTGTTTACATGCAGAATAAACATGATATTGCAGAAACAAAGCTCGTCTTCACGTTTAACCATCCATCCAAAGCCGTAAAGGATGAAGAGGGATGTGATAAATCAGATTACAGAGGATTACCACTAACCAACAATAGGCGTCAGGCCACCCTTACTTGGGATGTTCAGCAAGACAACATTATGCATGGCTTTGGAGGGTATTTTGATTGTACCCTTTATGGTAATGAAATGATCAGCATTGTTCCTGGTACACATAGCCCAGGAATGATCTCCTGGTTTCCAGTCTTTATTCCAATTAAGACACCAATGCGAGTACAAAAGGGTGATAAAATAACAGCAACGTTCTGGAGGTGTGTTGACTCGCGTCGTGTATGGTACGAATGGGTAGTTGAAGTGGGTAACCGATCAACACCACTGCACAATGCTAACGGTCGTAGTTCGGAAATGTTGCTTTAA

Protein

MAQQEISCGYEYIITADLQTCLTEALQCSYSFIVSPIIHPRFRRQSTNAGKNGGFTRSDMVLSPQDWTSRIVAKLSPYINVDSPSATVRQRHEDYLNEELSYCRGLGVPAIMISIHGRESNNLARILQTYYETSHHPSLIWACVPMLCSRTYRECTEDDEEEKAWNEPWYWWSKFHERLDWDKRVGVVLELSADLPSQEVVKRWLGEPVKAIIVPTSIFHNNKKGYPVLSRAHQQLVVSMVEHEAQVIVSGARRSNIEFFVQYLHRVWRRRPNPANDPMLSYARGWEDYLQTPLQPLADNLDTHTYNVFEKDPVKYNQYQKAIAQALIDVQKDRAVKQIAEYFQSKASCNVASINQCSKNELCDNNTKELIRDDPITVMVLGAGRGPLVRATFNASDITNTKVKVIAVEKNPCAVVVLAAQVREVWRNRDVVVIPGDMRQINLSPKADIIVSELLGSWGDNELSPECLDGASNLLKPGGISIPSSYRSYVAPITSPRLWAAAKIATSGIPQQKDKNLETLWVVYMQNKHDIAETKLVFTFNHPSKAVKDEEGCDKSDYRGLPLTNNRRQATLTWDVQQDNIMHGFGGYFDCTLYGNEMISIVPGTHSPGMISWFPVFIPIKTPMRVQKGDKITATFWRCVDSRRVWYEWVVEVGNRSTPLHNANGRSSEMLL

Description

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.

Uniprot

H9JE95   A0A2A4K2Y1   A0A194PII5   A0A194RDM7   A0A2H1WG18   S4PGH4   + More
A0A212FHC1   A0A437AZ02   E0VNL3   R7V8B5   C3XU33   V5GU64   A0A131Y2Z5   A0A0M8ZTS8   A0A154P963   A0A098M1P2   H9G5L9   A0A1B6GLL8   A0A1B6IMB0   A0A1B6M2Q8   T1DNU4   H3CR85   A0A1A7WWK2   A0A1A7YT50   A0A3M6TRZ9   A0A1S3LZK4   H2RYB1   A0A3P8X1P0   A0A3B3SCG5   A0A060YB35   A0A1W5AL92   A0A1A8MG24   A0A1A8SKI0   A0A1A8PNI8   A0A3P8XG33   A0A1A8B2V4   V3ZAC9   A0A1A8U3W9   A0A1A8KVM2   A0A1A8FMM9   A0A1A8IL56   A0A0C9RQJ5   A0A1A8QNI1   A0A1A8GM81   A0A1A8CSY4   A0A3Q1C9B7   A0A3P8TT70   A0A3B5A1R2   A0A3Q3BNR2   A0A3B4GT08   W5LPJ2   I3KEK7   A0A0P4VU44   A0A3Q2Y7P4   A0A0B7AFA1   A0A1A8DFE0   A0A315V2K3   A0A3P9C2U5   T1HH53   A0A3Q1GI48   A0A126Q9B4   A0A3Q3N6U7   B1A4A0   A0A3Q2UW47   A0A3Q0RDX6   A0A3B3VU87   A0A087YG86   A0A0N8JYF4   H2MAB6   A0A3B3VS17   S7NMG4   A0A3B3X304   L5KL20   K9IUI7   A0A3B4CWQ1   A0A3P9H1A5   A0A060XTB2   G1PLM4   A0A147A2T7   A0A3P9LXG4   A0A3Q2PPR1   A0A2U9BKH8   A0A3B4UD77   A0A1S3R5B9   A0A341B735   M3ZE42   A0A3B4WA79   A0A2Y9E9V3   A0A2U3V0A8   A0A2Y9LKP8   A0A383ZZU9   H0WRB3   G3SV33   D2HTW0   K1PDE4   I3MFE3   A0A3Q7QDE4   A0A2Y9HGY0   A0A2U3W2C0  

EC Number

2.1.1.-

Pubmed

19121390    26354079    23622113    22118469    20566863    23254933    + More
18563158    25765539    21881562    23758969    15496914    30382153    21551351    24487278    29240929    24755649    25069045    25329095    25186727    27129103    29703783    17554307    23258410    21993624    23542700    20010809    22992520   

EMBL

BABH01002781    NWSH01000248    PCG78040.1    KQ459602    KPI93226.1    KQ460367    + More
KPJ15559.1    ODYU01008424    SOQ52013.1    GAIX01003667    JAA88893.1    AGBW02008520    OWR53107.1    RSAL01000255    RVE43432.1    DS235340    EEB14969.1    AMQN01004756    KB294299    ELU14784.1    GG666464    EEN68407.1    GANP01010553    JAB73915.1    GEFM01002941    JAP72855.1    KQ435891    KOX69369.1    KQ434846    KZC08382.1    GBSI01000265    JAC96230.1    AAWZ02033594    GECZ01006566    JAS63203.1    GECU01019671    JAS88035.1    GEBQ01009770    JAT30207.1    GAAZ01000207    JAA97736.1    HADW01008671    SBP10071.1    HADX01011515    SBP33747.1    RCHS01003049    RMX44172.1    FR907391    CDQ86609.1    HAEF01014716    SBR55875.1    HAEI01015939    SBS18408.1    HAEG01008856    SBR82970.1    HADY01022546    SBP61031.1    KB202823    ESO87913.1    HAEJ01001341    SBS41798.1    HAEE01015644    SBR35694.1    HAEB01012837    SBQ59364.1    HAED01010893    SBQ97158.1    GBYB01009494    GBYB01009496    JAG79261.1    JAG79263.1    HAEH01012467    SBR94848.1    HAEC01003427    SBQ71504.1    HADZ01017870    SBP81811.1    AERX01045779    GDKW01000424    JAI56171.1    HACG01032834    CEK79699.1    HAEA01003521    SBQ32001.1    NHOQ01002364    PWA17409.1    ACPB03009098    KT694369    AMK01821.1    EU419765    ABZ90976.1    AYCK01004988    JARO02005677    KPP66385.1    KE164377    EPQ17645.1    KB030709    ELK11258.1    GABZ01001168    JAA52357.1    FR905556    CDQ80150.1    AAPE02039928    GCES01013495    JAR72828.1    CP026249    AWP04578.1    AAQR03175737    AAQR03175738    AAQR03175739    AAQR03175740    GL193372    EFB18958.1    JH819184    EKC21902.1    AGTP01099390   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000283053    + More
UP000009046    UP000014760    UP000001554    UP000053105    UP000076502    UP000001646    UP000007303    UP000275408    UP000087266    UP000005226    UP000265120    UP000261540    UP000193380    UP000192224    UP000265140    UP000030746    UP000257160    UP000265080    UP000261400    UP000264800    UP000261460    UP000018467    UP000005207    UP000264820    UP000265160    UP000015103    UP000257200    UP000261660    UP000264840    UP000261340    UP000261500    UP000028760    UP000034805    UP000001038    UP000261480    UP000010552    UP000261440    UP000265200    UP000001074    UP000265180    UP000265000    UP000246464    UP000261420    UP000252040    UP000002852    UP000261360    UP000248480    UP000245320    UP000248483    UP000261681    UP000005225    UP000007646    UP000005408    UP000005215    UP000286641    UP000248481    UP000245340   

PRIDE

H9JE95   

Pfam

PF17285   PRMT5_TIM        + More
PF17286   PRMT5_C
PF05185   PRMT5

Interpro

IPR035247   PRMT5_TIM        + More
IPR007857   Arg_MeTrfase_PRMT5       
IPR035248   PRMT5_C       
IPR025799   Arg_MeTrfase       
IPR035075   PRMT5       
IPR029063   SAM-dependent_MTases       

SUPFAM

SSF53335   SSF53335       

ProteinModelPortal

H9JE95   A0A2A4K2Y1   A0A194PII5   A0A194RDM7   A0A2H1WG18   S4PGH4   + More
A0A212FHC1   A0A437AZ02   E0VNL3   R7V8B5   C3XU33   V5GU64   A0A131Y2Z5   A0A0M8ZTS8   A0A154P963   A0A098M1P2   H9G5L9   A0A1B6GLL8   A0A1B6IMB0   A0A1B6M2Q8   T1DNU4   H3CR85   A0A1A7WWK2   A0A1A7YT50   A0A3M6TRZ9   A0A1S3LZK4   H2RYB1   A0A3P8X1P0   A0A3B3SCG5   A0A060YB35   A0A1W5AL92   A0A1A8MG24   A0A1A8SKI0   A0A1A8PNI8   A0A3P8XG33   A0A1A8B2V4   V3ZAC9   A0A1A8U3W9   A0A1A8KVM2   A0A1A8FMM9   A0A1A8IL56   A0A0C9RQJ5   A0A1A8QNI1   A0A1A8GM81   A0A1A8CSY4   A0A3Q1C9B7   A0A3P8TT70   A0A3B5A1R2   A0A3Q3BNR2   A0A3B4GT08   W5LPJ2   I3KEK7   A0A0P4VU44   A0A3Q2Y7P4   A0A0B7AFA1   A0A1A8DFE0   A0A315V2K3   A0A3P9C2U5   T1HH53   A0A3Q1GI48   A0A126Q9B4   A0A3Q3N6U7   B1A4A0   A0A3Q2UW47   A0A3Q0RDX6   A0A3B3VU87   A0A087YG86   A0A0N8JYF4   H2MAB6   A0A3B3VS17   S7NMG4   A0A3B3X304   L5KL20   K9IUI7   A0A3B4CWQ1   A0A3P9H1A5   A0A060XTB2   G1PLM4   A0A147A2T7   A0A3P9LXG4   A0A3Q2PPR1   A0A2U9BKH8   A0A3B4UD77   A0A1S3R5B9   A0A341B735   M3ZE42   A0A3B4WA79   A0A2Y9E9V3   A0A2U3V0A8   A0A2Y9LKP8   A0A383ZZU9   H0WRB3   G3SV33   D2HTW0   K1PDE4   I3MFE3   A0A3Q7QDE4   A0A2Y9HGY0   A0A2U3W2C0  

PDB

6CKC     E-value=3.17073e-141,     Score=1288

KEGG

101742218    K02516 type II protein arginine methyltransferase [EC:2.1.1.320] | (RefSeq) protein arginine N-methy

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0008168   GO:0035246   GO:0008469   GO:0005829   GO:0005634   GO:0034969   GO:0016301   GO:0044020   GO:0005794   GO:0042118   GO:0035243   GO:0035097   GO:0090161   GO:0046982   GO:0008327   GO:0042802   GO:0043021   GO:0002039   GO:1904992   GO:0000387   GO:0006353   GO:0034709   GO:0048742   GO:0006479   GO:0008270   GO:0015074   GO:0016817   GO:0043565   GO:0016876   GO:0043039  

PANTHER

PTHR10738  

Subcellular location

Cytoplasm  
Nucleus  

Length:

672

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.38487

Exp number, first 60 AAs:

0.09154

Total prob of N-in:

0.00546

outside

1  -  672

 

 

Pi

245.097288

Theta

182.776842

Tajima's D

1.087679

CLR

0.003529

CSRT

0.692065396730164

Interpretation

Uncertain