Gene

KWMTBOMO08848  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007849

Annotation

PREDICTED:_peptidyl-prolyl_cis-trans_isomerase-like_3_[Amyelois_transitella]

Location

Bomo_Chr15(-):6416232-6417487      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase      

Location in the cell

Cytoplasmic   Reliability : 2.177

CDS

ATGGCAGTTACTTTGCACACAGACGTCGGAGATATCAAGATTGAATTATATTGCGAGCAATGTCCGAAAGCGTGTGAGAATTTTCTAGCTCTATGTGCAAGTGATTACTATAATGGTTGTTTATTCCACAGGAATATAAAGGGATTTATAGTACAAACTGGTGATCCCACGGGAACTGGGAAAGGCGGTACGTCTATTTGGGGAAGAAAATTTGAAGATGAAATTAAGGATGAACTCAAGCATAACGCAAGAGGTGTAGTTAGTATGGCAAATAATGGGCCAAACACGAATGGAAGCCAATTTTTCATTACGTATGGAGAACAACCTCATCTAGATTTAAAATATACCATTTATGGAAGGGTAATCGATGGTTTTGAAGCATTAGATGATTTAGAGAAGATGCCAGTAAACCCCAAATCTTTTAGACCACTGACAGAAGCCAAGATCACATCTGTCACAATCCATGCAAATCCATTAGCTGGTTGA

Protein

MAVTLHTDVGDIKIELYCEQCPKACENFLALCASDYYNGCLFHRNIKGFIVQTGDPTGTGKGGTSIWGRKFEDEIKDELKHNARGVVSMANNGPNTNGSQFFITYGEQPHLDLKYTIYGRVIDGFEALDDLEKMPVNPKSFRPLTEAKITSVTIHANPLAG

Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the cyclophilin-type PPIase family.

Feature

chain  Peptidyl-prolyl cis-trans isomerase

Uniprot

H9JEA2   A0A2H1WJ72   A0A2A4JAM2   A0A2W1BD45   A0A212F4D4   S4P9B9   + More
A0A194RD88   A0A437AZH0   A0A2P8YU60   A0A1Y1MFK8   K7IQ40   R4G8X8   A0A154P9H6   Q17BY9   A0A2P6K894   T1I1J0   A0A0L7L7U9   A0A310SNE0   A0A2J7PZX5   A0A0L7R4V6   A0A293LYW0   A0A182QYZ3   A0A088AL11   A0A182SLX4   A0A2M3ZDQ8   A0A2M4AZI6   W5J938   A0A2S2PUY3   A0A067RDL9   E2AK76   A0A182Y696   A0A182VM70   A0A1I8MUN2   A0A1Y9G8C0   A0A2M4C2Q7   A0A3Q2CSC6   A0A1B6GEJ9   C4WWQ0   A0A2A3E2V0   A0A3Q2VFY8   A0A3P9CAB8   T1IY81   A0A2I4CHK6   I3JWZ3   M7AX56   A0A452HFU2   A0A1Q3F3E9   A0A2H8TT67   A0A1Y9IW56   A0A182XRH3   A0A1Y9GK79   T1K3Q1   E0VHM1   A0A0S7LI80   A0A3Q2Q055   A0A3B3XTE0   A0A087X5X8   A0A3B3VAG0   A0A1B6KKJ6   A0A1I8MUQ4   A0A3P8V9R4   A0A182MPD9   A0A1E1X1G0   K1QG06   A0A034VD64   A0A0L0BTY6   A0A2S2R563   A0A1A9V5A9   A0A3Q2VFB5   A0A3Q0TBJ9   A0A1S4H2N5   A0A3Q3QBU0   G3MMT0   A0A1B0B066   B0WXC4   A0A023EH91   A0A3Q3A7C1   A0A146Y7I2   B5XDC9   W8C1M2   G1KTF5   M3ZMK1   A0A3P8SP26   A0A1A8L2C9   A0A1A8NRD9   A0A1A8J9R9   A0A1A8C207   A0A1A8V230   A0A1B0AHR7   A0A3L8SEX4   A0A060W2F0   A0A315V1I5   A0A182KE94   H2L5B2   A0A151NA10   A0A1U8D0A2   A0A0K8UKR5   A0A218UXL1   A0A3M0LH82   U3JNH9  

EC Number

5.2.1.8

Pubmed

19121390    28756777    22118469    23622113    26354079    29403074    + More
28004739    20075255    17510324    26227816    20920257    23761445    24845553    20798317    25244985    25315136    25186727    23624526    28562605    20566863    24487278    28503490    22992520    25348373    26108605    12364791    22216098    24945155    20433749    24495485    23542700    30282656    24755649    29703783    17554307    22293439   

EMBL

BABH01002814    ODYU01008934    SOQ52952.1    NWSH01002160    PCG69021.1    KZ150252    + More
PZC71805.1    AGBW02010386    OWR48589.1    GAIX01005571    JAA86989.1    KQ460367    KPJ15572.1    RSAL01000249    RVE43499.1    PYGN01000357    PSN47775.1    GEZM01032428    GEZM01032427    JAV84582.1    GAHY01000197    JAA77313.1    KQ434831    KZC07830.1    CH477314    EAT43831.1    MWRG01021005    PRD22549.1    ACPB03005173    JTDY01002365    KOB71568.1    KQ761783    OAD57038.1    NEVH01020330    PNF21880.1    KQ414654    KOC65912.1    GFWV01007310    MAA32040.1    AXCN02001962    GGFM01005877    MBW26628.1    GGFK01012892    MBW46213.1    ADMH02002089    ETN59390.1    GGMR01020057    MBY32676.1    KK852703    KDR18079.1    GL440194    EFN66180.1    GGFJ01010147    MBW59288.1    GECZ01008900    JAS60869.1    ABLF02025743    AK342201    BAH72320.1    KZ288445    PBC25642.1    JH431671    AERX01033044    KB601989    EMP24343.1    GFDL01012996    JAV22049.1    GFXV01005621    MBW17426.1    APCN01001656    CAEY01001357    DS235171    EEB12907.1    GBYX01167793    JAO89185.1    AYCK01007136    GEBQ01028000    JAT11977.1    AXCM01000377    GFAC01006307    JAT92881.1    JH819183    EKC20481.1    GAKP01017736    GAKP01017735    GAKP01017730    GAKP01017726    JAC41216.1    JRES01001351    KNC23443.1    GGMS01015667    MBY84870.1    AAAB01008980    JO843181    AEO34798.1    JXJN01006587    DS234417    DS232162    EDS33933.1    EDS36454.1    GAPW01005362    JAC08236.1    GCES01036916    JAR49407.1    BT049048    ACI68849.1    GAMC01006934    JAB99621.1    HAEF01001236    SBR38618.1    HAEH01003574    HAEI01005408    SBR71613.1    HAED01019937    HAEE01004605    SBR06440.1    HADZ01009182    HAEA01009712    SBP73123.1    HADY01007118    HAEJ01013938    SBS54395.1    QUSF01000024    RLW01068.1    FR904374    CDQ61262.1    NHOQ01002408    PWA17104.1    AKHW03003682    KYO33616.1    GDHF01025158    JAI27156.1    MUZQ01000099    OWK58439.1    QRBI01000096    RMC18437.1    AGTO01000452   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000283053    UP000245037    + More
UP000002358    UP000076502    UP000008820    UP000015103    UP000037510    UP000235965    UP000053825    UP000075886    UP000005203    UP000075901    UP000000673    UP000027135    UP000000311    UP000076408    UP000075903    UP000095301    UP000069272    UP000265020    UP000007819    UP000242457    UP000264840    UP000265160    UP000192220    UP000005207    UP000031443    UP000291020    UP000075920    UP000076407    UP000075840    UP000015104    UP000009046    UP000265000    UP000261480    UP000028760    UP000261500    UP000265120    UP000075883    UP000005408    UP000037069    UP000078200    UP000261340    UP000261600    UP000092460    UP000002320    UP000264800    UP000087266    UP000001646    UP000002852    UP000265080    UP000092445    UP000276834    UP000193380    UP000075881    UP000001038    UP000050525    UP000189705    UP000197619    UP000269221    UP000016665   

PRIDE

H9JEA2   

Pfam

PF00160   Pro_isomerase

Interpro

IPR024936   Cyclophilin-type_PPIase        + More
IPR002130   Cyclophilin-type_PPIase_dom       
IPR020892   Cyclophilin-type_PPIase_CS       
IPR029000   Cyclophilin-like_dom_sf       

SUPFAM

SSF50891   SSF50891       

Gene 3D

2.40.100.10    

ProteinModelPortal

H9JEA2   A0A2H1WJ72   A0A2A4JAM2   A0A2W1BD45   A0A212F4D4   S4P9B9   + More
A0A194RD88   A0A437AZH0   A0A2P8YU60   A0A1Y1MFK8   K7IQ40   R4G8X8   A0A154P9H6   Q17BY9   A0A2P6K894   T1I1J0   A0A0L7L7U9   A0A310SNE0   A0A2J7PZX5   A0A0L7R4V6   A0A293LYW0   A0A182QYZ3   A0A088AL11   A0A182SLX4   A0A2M3ZDQ8   A0A2M4AZI6   W5J938   A0A2S2PUY3   A0A067RDL9   E2AK76   A0A182Y696   A0A182VM70   A0A1I8MUN2   A0A1Y9G8C0   A0A2M4C2Q7   A0A3Q2CSC6   A0A1B6GEJ9   C4WWQ0   A0A2A3E2V0   A0A3Q2VFY8   A0A3P9CAB8   T1IY81   A0A2I4CHK6   I3JWZ3   M7AX56   A0A452HFU2   A0A1Q3F3E9   A0A2H8TT67   A0A1Y9IW56   A0A182XRH3   A0A1Y9GK79   T1K3Q1   E0VHM1   A0A0S7LI80   A0A3Q2Q055   A0A3B3XTE0   A0A087X5X8   A0A3B3VAG0   A0A1B6KKJ6   A0A1I8MUQ4   A0A3P8V9R4   A0A182MPD9   A0A1E1X1G0   K1QG06   A0A034VD64   A0A0L0BTY6   A0A2S2R563   A0A1A9V5A9   A0A3Q2VFB5   A0A3Q0TBJ9   A0A1S4H2N5   A0A3Q3QBU0   G3MMT0   A0A1B0B066   B0WXC4   A0A023EH91   A0A3Q3A7C1   A0A146Y7I2   B5XDC9   W8C1M2   G1KTF5   M3ZMK1   A0A3P8SP26   A0A1A8L2C9   A0A1A8NRD9   A0A1A8J9R9   A0A1A8C207   A0A1A8V230   A0A1B0AHR7   A0A3L8SEX4   A0A060W2F0   A0A315V1I5   A0A182KE94   H2L5B2   A0A151NA10   A0A1U8D0A2   A0A0K8UKR5   A0A218UXL1   A0A3M0LH82   U3JNH9  

PDB

2OJU     E-value=3.50423e-68,     Score=650

KEGG

101743182    K12734 peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8] | (RefSeq) peptidyl-prolyl cis-trans

GO

GO:0003755   GO:0006457   GO:0000413   GO:0008270   GO:0015074   GO:0016817   GO:0043565   GO:0016876   GO:0043039  

Length:

161

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.000990000000000001

Exp number, first 60 AAs:

0.000710000000000001

Total prob of N-in:

0.11236

outside

1  -  161

 

 

Pi

33.902632

Theta

51.02818

Tajima's D

-1.030926

CLR

47.174345

CSRT

0.129943502824859

Interpretation

Possibly Positive selection