Gene

KWMTBOMO08846

Annotation

PREDICTED:_chondroitin_proteoglycan_2-like_[Plutella_xylostella]

Location

Bomo_Chr15(+):6402938-6404804      View in EpiBrowser

Full name

Protein obstructor-E      

Location in the cell

Extracellular   Reliability : 4.349

CDS

ATGCTCTCCTACATCTACCTCGCCTTGCTAGTGGCTGCAAGCCATGTCCAATCAACTCCCGCTGCTGCTACTGCCCAGAACGTAATCTGCAAAGCCCGCAATGGTTATTACAAAACAGACGCGAATTGTGATACATACATTGAATGCCGGGACTATCAAGCTACTAACATGATATGCCCGGATGGTCTGCACTTTAATCCTAGCGTGGAATGGCCGGCATATCCTTGCGGTTATCCAGTTGAAGTGACATGTGTAGGAAGAGGGAGCATCCAGCCTGCCCAAACAACACCGGATTGCCCGCACCAATATGGCATCTTCAAACATCCTAACGCTTCGCCCACCAATTGTGGCCAGTACCGAACATGCGTAGGTGGTCGTGCTTTCGACATGGTATGCCCGCCGGGACTAGCATTCAATCCAGACTTCAGCCGCTGTGACTGGGCCGACCTTGTACCTTCCTGTGATGCTGAAAAATTCTTGGGTTTCACTTGCCCCCCTGCTCCTTTGGATGCTATCGGCAATCCTCTGAATAATGTGATAAACTACAAGTACGAAGGCAACTGCTACTACTTCTTCTCCTGTGAGCAAAATCGGGCTAGATTGCTGTCCTGCGACATCGGTCTTGCATTCGACCCCACGACTGGACGGTGCGTCGACGCAGACAGAGTCCAGTGCAATGCAACGCAAAACACAAATGACAAGAATCATATATGA

Protein

MLSYIYLALLVAASHVQSTPAAATAQNVICKARNGYYKTDANCDTYIECRDYQATNMICPDGLHFNPSVEWPAYPCGYPVEVTCVGRGSIQPAQTTPDCPHQYGIFKHPNASPTNCGQYRTCVGGRAFDMVCPPGLAFNPDFSRCDWADLVPSCDAEKFLGFTCPPAPLDAIGNPLNNVINYKYEGNCYYFFSCEQNRARLLSCDIGLAFDPTTGRCVDADRVQCNATQNTNDKNHI

Description

Chitin-binding protein that is important for the longitudinal contraction and lateral expansion of the larval cuticle during its conversion into the oval-shaped puparium case. Essential for survival to the second instar larval stage. Confers the orientated contractility and expandability of the larval cuticle by regulating the arrangement of chitin and the formation of supracellular ridges on the cuticle of third instar larvae. Essential for determining pupal body shape; required for the orientated shape change of the cuticle during metamorphosis which involves changes in the morphology of the supracellular ridges.
Isoform A: Mainly involved in regulating pupal shape.
Isoform B: Mainly involved in larvae survival, possibly by maintaining the normal morphology of the larval hindgut during development.

Keywords

Alternative splicing   Chitin-binding   Complete proteome   Cuticle   Disulfide bond   Extracellular matrix   Glycoprotein   Reference proteome   Repeat   Secreted   Signal  

Feature

chain  Protein obstructor-E
splice variant  In isoform A.

Uniprot

A0A2W1BF23   A0A2A4JBU2   A0A3S2N7I4   A0A212F4E7   A0A212F4E4   A0A194PQG3   + More
A0A194PWP1   A0A194PS25   A0A194RE65   A0A194PQ33   A0A194RDP2   A0A212F4D0   A0A194QP38   I4DML9   A0A194PQ28   I4DNE9   A0A0L7KUM0   A0A0F6PN10   A0A1B6D857   K7ILZ1   A0A3S2LC51   A0A3S2LTG2   D1MAI7   A0A1Y1N6X3   A0A026W6E9   A0A0F6PMG7   E9JDK5   A0A151X4R9   A0A195BCC5   A0A2J7RMS5   A0A195FXS8   A0A195DE51   F4WJU2   A0A158NS31   A0A151ILF7   A0A067RK54   A0A0A1WW87   A0A034W0W1   E2AYK3   A0A2S1ZS46   A0A2H1WIQ5   A0A2A4JAB4   A0A1B0D1P0   A0A023F905   A0A0K8V2U4   A0A212F4E1   A0A0C9QB70   A0A2Y9D4S8   A0A2W1B9A5   A0A224XY50   A0A1I8MZF1   A0A2M4BZ99   R4FMJ4   W8C6S2   A0A182IT75   J3JX93   A0A2S2R3N9   A0A0L7R0S2   U4UB08   N6TSA9   A0A1I8N1E5   A0A1D2MQI6   A0A2H8TE74   A0A154PAJ4   E0VLN7   A0A2S2PMI9   A0A146M7V2   A0A0A9VVQ8   A0A0L0BWY5   W5J7F5   A0A182VUQ9   A0A336MRH4   A0A2A3ED73   A0A182F1V8   A0A0K8SP49   A0A226F411   A0A1W4W557   B4M9J0   J9JK90   T1DNE2   A0A310S848   A0A088AMM7   B3MMM2   A0A2R7VZS5   A0A182RG78   B4JC70   A0A0K8SQI3   A0A0J9QWD0   B4I1K3   A0A0R1DTS6   Q9VMM6-2   A0A182SDT0   A0A182KBC6   A0A182YFW5   B4KGZ8   A0A0Q5WIN5   A0A182QV04   E2C2F8   A0A1J1HSH1  

Pubmed

28756777    22118469    26354079    22651552    26227816    20075255    + More
18362917    20144715    19820115    28004739    24508170    21282665    21719571    21347285    24845553    25830018    25348373    20798317    29712872    25474469    25315136    24495485    22516182    23537049    27289101    20566863    26823975    25401762    26108605    20920257    23761445    17994087    22936249    17550304    10731132    12537572    12537569    28076349    25244985   

EMBL

KZ150252    PZC71807.1    NWSH01002160    PCG69024.1    RSAL01000249    RVE43503.1    + More
AGBW02010386    OWR48593.1    OWR48592.1    KQ459596    KPI95552.1    KPI95555.1    KPI95554.1    KQ460367    KPJ15575.1    KPI95556.1    KPJ15574.1    OWR48591.1    KQ461195    KPJ06740.1    AK402537    BAM19159.1    KPI95551.1    AK402874    BAM19439.1    JTDY01005687    KOB66751.1    KM099164    AJZ68825.1    GEDC01015415    JAS21883.1    RVE43501.1    RVE43504.1    GU128095    KQ971379    ACY95478.1    EEZ97505.1    GEZM01014692    JAV92036.1    KK107374    EZA51588.1    KM099165    AJZ68826.1    GL771873    EFZ09095.1    KQ982544    KYQ55351.1    KQ976528    KYM81872.1    NEVH01002552    PNF42122.1    KQ981208    KYN44649.1    KQ980989    KYN10704.1    GL888186    EGI65584.1    ADTU01024435    KQ977142    KYN05321.1    KK852463    KDR23408.1    GBXI01011522    JAD02770.1    GAKP01011200    GAKP01011197    JAC47755.1    GL443918    EFN61491.1    MF942766    AWK28289.1    ODYU01008934    SOQ52949.1    PCG69025.1    AJVK01010349    GBBI01001268    JAC17444.1    GDHF01019097    JAI33217.1    OWR48594.1    GBYB01000481    GBYB01000484    JAG70248.1    JAG70251.1    PZC71808.1    GFTR01003417    JAW13009.1    GGFJ01009201    MBW58342.1    ACPB03017897    GAHY01001694    JAA75816.1    GAMC01004089    JAC02467.1    BT127862    AEE62824.1    GGMS01015382    MBY84585.1    KQ414670    KOC64447.1    KB632275    ERL91099.1    APGK01053934    KB741239    ENN72125.1    LJIJ01000684    ODM95337.1    GFXV01000584    MBW12389.1    KQ434857    KZC08861.1    DS235277    EEB14293.1    GGMR01018043    MBY30662.1    GDHC01003793    JAQ14836.1    GBHO01044323    JAF99280.1    JRES01001211    KNC24558.1    ADMH02002118    ETN58800.1    UFQS01000186    UFQS01002158    UFQT01000186    UFQT01002158    SSX00899.1    SSX32816.1    KZ288280    PBC29660.1    GBRD01010738    JAG55086.1    LNIX01000001    OXA64509.1    CH940654    EDW57866.1    ABLF02021901    ABLF02021903    GAMD01002960    JAA98630.1    KQ764887    OAD54244.1    CH902620    EDV31913.1    KK854198    PTY12972.1    CH916368    EDW03083.1    GBRD01010739    JAG55085.1    CM002910    KMY88366.1    CH480820    EDW54410.1    CM000157    KRJ98086.1    AE014134    AY069031    BT099959    BT001600    AAL39176.1    AAN71355.1    ACX47660.1    CH933807    EDW12209.1    CH954177    KQS70190.1    AXCN02000847    GL452124    EFN77908.1    CVRI01000020    CRK90931.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000053268    UP000053240    UP000037510    + More
UP000002358    UP000007266    UP000053097    UP000075809    UP000078540    UP000235965    UP000078541    UP000078492    UP000007755    UP000005205    UP000078542    UP000027135    UP000000311    UP000092462    UP000095300    UP000095301    UP000015103    UP000075880    UP000053825    UP000030742    UP000019118    UP000094527    UP000076502    UP000009046    UP000037069    UP000000673    UP000075920    UP000242457    UP000069272    UP000198287    UP000192223    UP000008792    UP000007819    UP000005203    UP000007801    UP000075900    UP000001070    UP000001292    UP000002282    UP000000803    UP000075901    UP000075881    UP000076408    UP000009192    UP000008711    UP000075886    UP000008237    UP000183832   

PRIDE

Q9VMM6   

Pfam

PF01607   CBM_14

Interpro

IPR002557   Chitin-bd_dom        + More
IPR036508   Chitin-bd_dom_sf       

SUPFAM

SSF57625   SSF57625       

ProteinModelPortal

A0A2W1BF23   A0A2A4JBU2   A0A3S2N7I4   A0A212F4E7   A0A212F4E4   A0A194PQG3   + More
A0A194PWP1   A0A194PS25   A0A194RE65   A0A194PQ33   A0A194RDP2   A0A212F4D0   A0A194QP38   I4DML9   A0A194PQ28   I4DNE9   A0A0L7KUM0   A0A0F6PN10   A0A1B6D857   K7ILZ1   A0A3S2LC51   A0A3S2LTG2   D1MAI7   A0A1Y1N6X3   A0A026W6E9   A0A0F6PMG7   E9JDK5   A0A151X4R9   A0A195BCC5   A0A2J7RMS5   A0A195FXS8   A0A195DE51   F4WJU2   A0A158NS31   A0A151ILF7   A0A067RK54   A0A0A1WW87   A0A034W0W1   E2AYK3   A0A2S1ZS46   A0A2H1WIQ5   A0A2A4JAB4   A0A1B0D1P0   A0A023F905   A0A0K8V2U4   A0A212F4E1   A0A0C9QB70   A0A2Y9D4S8   A0A2W1B9A5   A0A224XY50   A0A1I8MZF1   A0A2M4BZ99   R4FMJ4   W8C6S2   A0A182IT75   J3JX93   A0A2S2R3N9   A0A0L7R0S2   U4UB08   N6TSA9   A0A1I8N1E5   A0A1D2MQI6   A0A2H8TE74   A0A154PAJ4   E0VLN7   A0A2S2PMI9   A0A146M7V2   A0A0A9VVQ8   A0A0L0BWY5   W5J7F5   A0A182VUQ9   A0A336MRH4   A0A2A3ED73   A0A182F1V8   A0A0K8SP49   A0A226F411   A0A1W4W557   B4M9J0   J9JK90   T1DNE2   A0A310S848   A0A088AMM7   B3MMM2   A0A2R7VZS5   A0A182RG78   B4JC70   A0A0K8SQI3   A0A0J9QWD0   B4I1K3   A0A0R1DTS6   Q9VMM6-2   A0A182SDT0   A0A182KBC6   A0A182YFW5   B4KGZ8   A0A0Q5WIN5   A0A182QV04   E2C2F8   A0A1J1HSH1  

PDB

6G9E     E-value=8.1171e-05,     Score=107

KEGG

101743600    no KO assigned | (RefSeq) uncharacterized LOC101743600

GO

GO:0006030   GO:0008061   GO:0005576   GO:0016021   GO:0042302   GO:0005615   GO:0015986   GO:0015074   GO:0016817   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

Subcellular location

  

SignalP

Position:   1 - 18,         Likelihood:  0.997355

 

 

Length:

237

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.20277

Exp number, first 60 AAs:

0.20239

Total prob of N-in:

0.01648

outside

1  -  237

 

 

Pi

169.882764

Theta

211.736028

Tajima's D

-0.773702

CLR

0

CSRT

0.184690765461727

Interpretation

Uncertain