Gene

KWMTBOMO08845  Validated by peptides from experiments

Annotation

PREDICTED:_uncharacterized_protein_LOC105381104_[Plutella_xylostella]

Location

Bomo_Chr15(+):6385538-6398813      View in EpiBrowser

Full name

Protein obstructor-E      

Location in the cell

Extracellular   Reliability : 3.017

CDS

ATGGAGAGGACTTTTGTGATCTTGACGTGCTTTTGCGCCTTTGTTTACACACAAACACAGTACCAGCCTTTTGGACAGACAAATCGCTTCCAAAATCAGTACCAGGAACAAGCACCCGTCAGGCCTACTGGACAATGCAGGGAACTGAACGAAAGGTATCCAGTGTCCGGAAGCTGCGACAGATATATTGAATGCATCAATGGAACCGCTGAAGAGAAACTATGCCCCGATGGTCTCCGTTACAATCCCAACGTGAATTTCGATGTATATCCGTGCCAGTACCCTAACGAAGTGCCGTGTCTCGAACGATCCTCGCTACAGCCACCGCAACCGACAGAATTGTGTCCCCATCAATTCGGATACTTCAAATTAGGCGACGCCCGCAATTGCAGCGGATTCAGAAACTGCGTGAACGGTGTAGGCTACGATTTTGTATGTCCCGACGGACTGGCTTTCAATTCTGAGACCTACCGCTGCGAATGGCCTGATGAAGTCGCCGACTGCGATGCTGAAGCTTTCCTCGGATTCCGTTGCCCCGAAGTACCAATAAGTAGAGAACTTGGTCCCCCAGCCGGATATAGATACTACAGGTCTGACAACAATTGCCAGAAGTATTTCCTGTGCATCGATGGGCATCCTCGCGTCCTCTATTGCGGTGGTGAGTCCGCATTCGACGATCTAACCTCAACATGTGTCTCCGCCGATGAAGTAGGAGCATGTCCTGCTGAGCTAAGGGCCGCAGCAGTCCGTGCCAAGGACGACGCAAAGCAACTGCTCGCCAAAGAAGTCGAATTCAATGCGTATCAGCTAACACGAAAACCGTCATTAAGCTATAGAAATTAA

Protein

MERTFVILTCFCAFVYTQTQYQPFGQTNRFQNQYQEQAPVRPTGQCRELNERYPVSGSCDRYIECINGTAEEKLCPDGLRYNPNVNFDVYPCQYPNEVPCLERSSLQPPQPTELCPHQFGYFKLGDARNCSGFRNCVNGVGYDFVCPDGLAFNSETYRCEWPDEVADCDAEAFLGFRCPEVPISRELGPPAGYRYYRSDNNCQKYFLCIDGHPRVLYCGGESAFDDLTSTCVSADEVGACPAELRAAAVRAKDDAKQLLAKEVEFNAYQLTRKPSLSYRN

Description

Chitin-binding protein that is important for the longitudinal contraction and lateral expansion of the larval cuticle during its conversion into the oval-shaped puparium case. Essential for survival to the second instar larval stage. Confers the orientated contractility and expandability of the larval cuticle by regulating the arrangement of chitin and the formation of supracellular ridges on the cuticle of third instar larvae. Essential for determining pupal body shape; required for the orientated shape change of the cuticle during metamorphosis which involves changes in the morphology of the supracellular ridges.
Isoform A: Mainly involved in regulating pupal shape.
Isoform B: Mainly involved in larvae survival, possibly by maintaining the normal morphology of the larval hindgut during development.

Keywords

Alternative splicing   Chitin-binding   Complete proteome   Cuticle   Disulfide bond   Extracellular matrix   Glycoprotein   Reference proteome   Repeat   Secreted   Signal  

Feature

chain  Protein obstructor-E
splice variant  In isoform A.

Uniprot

A0A2H1WIQ5   A0A3S2LTG2   A0A0L7KUM0   A0A2A4JAB4   I4DNE9   A0A194PQ28   + More
A0A194QP38   A0A2W1B9A5   I4DML9   A0A212F4E1   N6TSA9   J3JX93   U4UB08   A0A2S1ZS46   A0A1B6FYU4   A0A0C9QB70   E2AYK3   F4WJU2   E9JDK5   A0A026W6E9   A0A1B0D1P0   A0A151ILF7   A0A158NS31   W8C6S2   A0A195FXS8   A0A088AMM7   A0A195DE51   A0A1I8MZF1   A0A0A1WW87   A0A151X4R9   A0A1I8N1E5   A0A034W0W1   A0A195BCC5   A0A182U3V1   A0A0K8V2U4   A0A310S848   B4M9J0   B4JC70   E2C2F8   A0A2S2R3N9   A0A2Y9D4S8   B3MMM2   B4KGZ8   A0A0R1DTS6   A0A0Q5WIN5   A0A0F6PN10   A0A336MRH4   A0A0J9QWD0   B4I1K3   B4G6V9   A0A3B0K058   Q29PJ8   Q9VMM6-2   A0A0L0BWY5   A0A182MMN6   J9JK90   A0A0L7R0S2   A0A1W4V6C9   A0A1A9X061   A0A067RK54   A0A2J7RMS5   E0VLN7   A0A1B0A3U7   A0A1Y1N6X3  

Pubmed

26227816    22651552    26354079    28756777    22118469    23537049    + More
22516182    29712872    20798317    21719571    21282665    24508170    21347285    24495485    25315136    25830018    25348373    17994087    17550304    22936249    15632085    10731132    12537572    12537569    28076349    26108605    24845553    20566863    28004739   

EMBL

ODYU01008934    SOQ52949.1    RSAL01000249    RVE43504.1    JTDY01005687    KOB66751.1    + More
NWSH01002160    PCG69025.1    AK402874    BAM19439.1    KQ459596    KPI95551.1    KQ461195    KPJ06740.1    KZ150252    PZC71808.1    AK402537    BAM19159.1    AGBW02010386    OWR48594.1    APGK01053934    KB741239    ENN72125.1    BT127862    AEE62824.1    KB632275    ERL91099.1    MF942766    AWK28289.1    GECZ01014417    GECZ01001757    JAS55352.1    JAS68012.1    GBYB01000481    GBYB01000484    JAG70248.1    JAG70251.1    GL443918    EFN61491.1    GL888186    EGI65584.1    GL771873    EFZ09095.1    KK107374    EZA51588.1    AJVK01010349    KQ977142    KYN05321.1    ADTU01024435    GAMC01004089    JAC02467.1    KQ981208    KYN44649.1    KQ980989    KYN10704.1    GBXI01011522    JAD02770.1    KQ982544    KYQ55351.1    GAKP01011200    GAKP01011197    JAC47755.1    KQ976528    KYM81872.1    GDHF01019097    JAI33217.1    KQ764887    OAD54244.1    CH940654    EDW57866.1    CH916368    EDW03083.1    GL452124    EFN77908.1    GGMS01015382    MBY84585.1    CH902620    EDV31913.1    CH933807    EDW12209.1    CM000157    KRJ98086.1    CH954177    KQS70190.1    KM099164    AJZ68825.1    UFQS01000186    UFQS01002158    UFQT01000186    UFQT01002158    SSX00899.1    SSX32816.1    CM002910    KMY88366.1    CH480820    EDW54410.1    CH479180    EDW28278.1    OUUW01000010    SPP86042.1    CH379058    EAL34295.2    AE014134    AY069031    BT099959    BT001600    AAL39176.1    AAN71355.1    ACX47660.1    JRES01001211    KNC24558.1    AXCM01000061    ABLF02021901    ABLF02021903    KQ414670    KOC64447.1    KK852463    KDR23408.1    NEVH01002552    PNF42122.1    DS235277    EEB14293.1    GEZM01014692    JAV92036.1   

Proteomes

UP000283053    UP000037510    UP000218220    UP000053268    UP000053240    UP000007151    + More
UP000019118    UP000030742    UP000000311    UP000007755    UP000053097    UP000092462    UP000078542    UP000005205    UP000078541    UP000005203    UP000078492    UP000095301    UP000075809    UP000078540    UP000075902    UP000008792    UP000001070    UP000008237    UP000095300    UP000007801    UP000009192    UP000002282    UP000008711    UP000001292    UP000008744    UP000268350    UP000001819    UP000000803    UP000037069    UP000075883    UP000007819    UP000053825    UP000192221    UP000091820    UP000027135    UP000235965    UP000009046    UP000092445   

PRIDE

Q9VMM6   

Pfam

PF01607   CBM_14

Interpro

IPR036508   Chitin-bd_dom_sf        + More
IPR002557   Chitin-bd_dom       

SUPFAM

SSF57625   SSF57625       

ProteinModelPortal

A0A2H1WIQ5   A0A3S2LTG2   A0A0L7KUM0   A0A2A4JAB4   I4DNE9   A0A194PQ28   + More
A0A194QP38   A0A2W1B9A5   I4DML9   A0A212F4E1   N6TSA9   J3JX93   U4UB08   A0A2S1ZS46   A0A1B6FYU4   A0A0C9QB70   E2AYK3   F4WJU2   E9JDK5   A0A026W6E9   A0A1B0D1P0   A0A151ILF7   A0A158NS31   W8C6S2   A0A195FXS8   A0A088AMM7   A0A195DE51   A0A1I8MZF1   A0A0A1WW87   A0A151X4R9   A0A1I8N1E5   A0A034W0W1   A0A195BCC5   A0A182U3V1   A0A0K8V2U4   A0A310S848   B4M9J0   B4JC70   E2C2F8   A0A2S2R3N9   A0A2Y9D4S8   B3MMM2   B4KGZ8   A0A0R1DTS6   A0A0Q5WIN5   A0A0F6PN10   A0A336MRH4   A0A0J9QWD0   B4I1K3   B4G6V9   A0A3B0K058   Q29PJ8   Q9VMM6-2   A0A0L0BWY5   A0A182MMN6   J9JK90   A0A0L7R0S2   A0A1W4V6C9   A0A1A9X061   A0A067RK54   A0A2J7RMS5   E0VLN7   A0A1B0A3U7   A0A1Y1N6X3  

PDB

6G9E     E-value=0.000206256,     Score=104

KEGG

101743739    no KO assigned | (RefSeq) uncharacterized LOC101743739

GO

GO:0005576   GO:0008061   GO:0006030   GO:0016021   GO:0042302   GO:0005615   GO:0015986   GO:0015074   GO:0016817   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

Subcellular location

  

SignalP

Position:   1 - 17,         Likelihood:  0.980386

 

 

Length:

280

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.09999

Exp number, first 60 AAs:

2.09985

Total prob of N-in:

0.14764

outside

1  -  280

 

 

Pi

151.303392

Theta

154.963588

Tajima's D

0

CLR

112.923955

CSRT

0.369281535923204

Interpretation

Uncertain