Gene

KWMTBOMO08797  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007879

Annotation

ribosomal_protein_L5_[Bombyx_mori]

Location

Bomo_Chr15(-):5475794-5480567      View in EpiBrowser

Full name

60S ribosomal protein L5      

Location in the cell

Cytoplasmic   Reliability : 2.817

CDS

ATGGGATTCGTTAAAGTTGTGAAGAACAAACAATACTTCAAGAGGTACCAAGTAAAATTCAAGAGGCGTCGTGAAGGGAAAACTGATTATTATGCTCGTAAACGCCTCGTTGTTCAGGACAAGAACAAATATAACACACCTAAATATCGTCTGATTGTGCGTCTCTCCAACAAAGATGTAACATGCCAGGTGGCCTACTCTCGGATTGAAGGTGACCATATTGTGTGCGCTGCTTATTCACATGAGTTGCCACGTTATGGTGTGAAGGTTGGTCTGACAAATTATGCTGCAGCATATTCAACTGGTCTGCTATTAGCACGAAGACTGCTTCAAAGACTTGGACTTGACACCTTATACACTGGCACAACAGATGTCACAGGTGATGAATACAATGTTGAACCTGTCGACAATGGACCAGGAGCATTTAGATGTTATTTGGATGTAGGCTTAGCACGCACCACTACTGGTGCTCGTGTCTTTGGAGCTATGAAGGGTGCTGTTGACGGTGGCCTCAATGTTCCTCATTCCATCAAAAGATTCCCTGGCTATGATGCAGAATCCAAAAAGTTCAATGCTGAAGTACACAGGGCTCACATCTTTGGTTTGCATGTTGCTGAATACATGAGAAGTCTTGAACAGGATGATGAGGATTCTTTCAAGAGACAATTCAGCAAGTACATAAAACTAGGAGTCACTGCAGATGCTATTGAAGCCATCTACAAGAAAGCCCATGAAGCCATCCGTGCGGATCCATCCCACAAGAAGAAAGAGTTAAAGAAAGACTCTGTCAAACAGAAGCGCTGGAACAAACGCAAGCTAACATTGGCCGAGAGGAAAAACAGAATCAAGCAAAAGAAGGCTTCCTTCATCAAGAGACTGCAGGCTCAGGCGGAAGCTTAA

Protein

MGFVKVVKNKQYFKRYQVKFKRRREGKTDYYARKRLVVQDKNKYNTPKYRLIVRLSNKDVTCQVAYSRIEGDHIVCAAYSHELPRYGVKVGLTNYAAAYSTGLLLARRLLQRLGLDTLYTGTTDVTGDEYNVEPVDNGPGAFRCYLDVGLARTTTGARVFGAMKGAVDGGLNVPHSIKRFPGYDAESKKFNAEVHRAHIFGLHVAEYMRSLEQDDEDSFKRQFSKYIKLGVTADAIEAIYKKAHEAIRADPSHKKKELKKDSVKQKRWNKRKLTLAERKNRIKQKKASFIKRLQAQAEA

Description

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

Subunit

Component of the large ribosomal subunit (LSU).
Component of the large ribosomal subunit (LSU) (By similarity). Interacts with Fmr1 to form the RNA-induced silencing complex (RISC), a ribonucleoprotein (RNP) complex involved in translation regulation, other components of the complex are Rm62, RpL11, AGO2 and Dcr-1 (PubMed:12368261).

Similarity

Belongs to the universal ribosomal protein uL18 family.

Keywords

Complete proteome   Cytoplasm   Nucleus   Reference proteome   Ribonucleoprotein   Ribosomal protein   RNA-binding   rRNA-binding   3D-structure  

Feature

chain  60S ribosomal protein L5

Uniprot

O76190   H9JED2   A0A0K8TB46   A0A2H1W0H4   A0A2A4K784   D1LYN1   + More
I4DMF0   I4DIE6   A0A3G1T1E0   G0ZEG6   E7DZ48   A0A194PPY4   A0A3S2LT35   A0A212F0W0   A0A194QMD8   S4NXJ6   A0A0L7LFV2   A0A023F991   A0A1W4WJA3   A0A171B7W3   A0A0P4VPV1   R4G4H5   A0A0V0G4U8   A0A069DYI7   D6X3F5   A0A0L0C424   V5GSH1   A0A1L8EFC6   W8BVZ4   A0A0A1WRV4   A0A0K8WI81   A0A034VBG0   A0A1I8PZD8   A0A1L8ECA2   E2J7J3   A0A0C9RVK6   A0A3L8DRX6   A0A1B6IR15   A0A232ELB8   A0A1B6FEB1   A0A0J9TT72   B4IT18   B3NKK9   R9Q794   Q9W5R8   A0A1W4VZZ4   A0A1S3D5P5   A0A3B0JWU1   B5DK39   B4GXB8   A0A411G6Z2   B4MZH3   A0A2J7QXC0   E9J1P1   R4WI84   B4IKU1   A0A0A9WEV0   A0A2P8Z0E6   B3N025   G8CV14   T1PF40   E2AVY1   A0A158P454   A0A0K8TPM6   A0A0J7KN78   A0A224XH06   A0A0U3YU67   A0A151J8T2   A0A1B6M3J2   A0A151JVK1   A0A1Z1EBN7   A0A1B6C7B9   A0A067QR79   A0A2A3E1T0   V9IKZ0   A0A088AL09   Q4GXN2   A0A1A9WES3   A0A1Y1NAU7   A0A1A9UWU9   A0A1B0DNJ2   A0A0Q9WH39   A0A1A9ZW12   D3TQT3   A0A1L8DSE7   U5EMG6   A0A1A9YL61   A0A1B0C5G4   E2C451   A0A336LZX8   E2BZ60   A0A0M5J241   A0A0X7YC68   Q56FG6   A0A0Q9XHF5   A0A336KFF3   R4UMZ3   A0A026VYU9   A0A195CNX3   A0A151WVK2  

Pubmed

19121390    22651552    26354079    22118469    23622113    26227816    + More
25474469    27129103    26334808    18362917    19820115    26108605    24495485    25830018    25348373    30249741    28648823    22936249    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12537569    12368261    23636399    15632085    21282665    23691247    25401762    26823975    29403074    22028913    25315136    20798317    21347285    26369729    24845553    28004739    20353571    24508170   

EMBL

AF008229    AY769272    BABH01002903    GBRD01003048    JAG62773.1    ODYU01005599    + More
SOQ46605.1    NWSH01000105    PCG79512.1    GU084305    ACY95338.1    AK402468    BAM19090.1    AK401064    BAM17686.1    MG846931    AXY94783.1    JF265044    AEL28875.1    HQ424751    ADT80695.1    KQ459596    KPI95506.1    RSAL01000266    RVE43247.1    AGBW02011012    OWR47385.1    KQ461195    KPJ06697.1    GAIX01014170    JAA78390.1    JTDY01001240    KOB74433.1    GBBI01000767    JAC17945.1    GEMB01000170    JAS02943.1    GDKW01001564    JAI55031.1    ACPB03003517    GAHY01001355    JAA76155.1    GECL01003767    JAP02357.1    GBGD01002320    JAC86569.1    KQ971374    EEZ97412.1    JRES01000940    KNC26992.1    GALX01001352    JAB67114.1    GFDG01001484    JAV17315.1    GAMC01013196    JAB93359.1    GBXI01013047    JAD01245.1    GDHF01001565    JAI50749.1    GAKP01019510    JAC39442.1    GFDG01002560    JAV16239.1    HP429411    ADN29911.1    GBYB01012980    JAG82747.1    QOIP01000005    RLU22609.1    GECU01018356    JAS89350.1    NNAY01003579    OXU19159.1    GECZ01021234    JAS48535.1    CM002910    KMY91435.1    CH891638    EDW99408.1    CH954179    EDV54313.2    AE014134    EAA46017.3    EAA46020.2    AY071305    OUUW01000010    SPP85543.1    CH379061    EDY70665.1    CH479195    EDW27229.1    MH365870    QBB01679.1    CH963920    EDW77758.1    NEVH01009381    PNF33236.1    GL767674    EFZ13276.1    AK417075    BAN20290.1    CH480857    EDW52699.1    GBHO01036632    GBRD01013496    GDHC01003711    JAG06972.1    JAG52330.1    JAQ14918.1    PYGN01000255    PSN49977.1    CH902638    EDV35391.2    HQ385973    ADQ73874.1    KA647412    AFP62041.1    GL443213    EFN62403.1    ADTU01008609    GDAI01001284    JAI16319.1    LBMM01005224    KMQ91699.1    GFTR01004649    JAW11777.1    KT185023    ALX81342.1    KQ979480    KYN21270.1    GEBQ01009517    JAT30460.1    KQ981701    KYN37484.1    KX379234    ARB43936.1    GEDC01027974    JAS09324.1    KK853055    KDR11979.1    KZ288445    PBC25648.1    JR052509    AEY61710.1    AM048991    CAJ17229.1    GEZM01013118    JAV92737.1    AJVK01017586    AJVK01017587    CH940649    KRF81121.1    CCAG010005354    EZ423785    ADD20061.1    GFDF01004777    JAV09307.1    GANO01001039    JAB58832.1    JXJN01025969    GL452396    EFN77280.1    UFQS01000363    UFQT01000363    SSX03178.1    SSX23544.1    GL451566    EFN79020.1    CP012523    ALC40406.1    KC507327    AHB12450.1    AY961534    CH933807    KRG03064.1    SSX03179.1    SSX23545.1    KC740666    AGM32490.1    KK107570    EZA48850.1    KQ977513    KYN02177.1    KQ982708    KYQ51797.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000283053    UP000007151    UP000053240    + More
UP000037510    UP000192223    UP000015103    UP000007266    UP000037069    UP000095300    UP000279307    UP000215335    UP000002282    UP000008711    UP000000803    UP000192221    UP000079169    UP000268350    UP000001819    UP000008744    UP000007798    UP000235965    UP000001292    UP000245037    UP000007801    UP000095301    UP000000311    UP000005205    UP000036403    UP000078492    UP000078541    UP000027135    UP000242457    UP000005203    UP000091820    UP000078200    UP000092462    UP000008792    UP000092445    UP000092444    UP000092443    UP000092460    UP000008237    UP000092553    UP000009192    UP000053097    UP000078542    UP000075809   

PRIDE

O76190    H9JED2    Q9W5R8    Q56FG6   

Pfam

PF14204   Ribosomal_L18_c        + More
PF17144   Ribosomal_L5e
PF00505   HMG_box
PF01119   DNA_mis_repair

Interpro

IPR025607   Rbsml_L5e/L18P_C        + More
IPR005485   Rbsml_L5_euk/L18_arc       
IPR009071   HMG_box_dom       
IPR036910   HMG_box_dom_sf       
IPR003594   HATPase_C       
IPR036890   HATPase_C_sf       
IPR013507   DNA_mismatch_S5_2-like       
IPR014762   DNA_mismatch_repair_CS       
IPR014721   Ribosomal_S5_D2-typ_fold_subgr       
IPR020568   Ribosomal_S5_D2-typ_fold       

SUPFAM

SSF47095   SSF47095        + More
SSF55874   SSF55874       
SSF54211   SSF54211       

Gene 3D

1.10.30.10     3.30.565.10     3.30.230.10    

CDD

cd00075  HATPase_c

ProteinModelPortal

O76190   H9JED2   A0A0K8TB46   A0A2H1W0H4   A0A2A4K784   D1LYN1   + More
I4DMF0   I4DIE6   A0A3G1T1E0   G0ZEG6   E7DZ48   A0A194PPY4   A0A3S2LT35   A0A212F0W0   A0A194QMD8   S4NXJ6   A0A0L7LFV2   A0A023F991   A0A1W4WJA3   A0A171B7W3   A0A0P4VPV1   R4G4H5   A0A0V0G4U8   A0A069DYI7   D6X3F5   A0A0L0C424   V5GSH1   A0A1L8EFC6   W8BVZ4   A0A0A1WRV4   A0A0K8WI81   A0A034VBG0   A0A1I8PZD8   A0A1L8ECA2   E2J7J3   A0A0C9RVK6   A0A3L8DRX6   A0A1B6IR15   A0A232ELB8   A0A1B6FEB1   A0A0J9TT72   B4IT18   B3NKK9   R9Q794   Q9W5R8   A0A1W4VZZ4   A0A1S3D5P5   A0A3B0JWU1   B5DK39   B4GXB8   A0A411G6Z2   B4MZH3   A0A2J7QXC0   E9J1P1   R4WI84   B4IKU1   A0A0A9WEV0   A0A2P8Z0E6   B3N025   G8CV14   T1PF40   E2AVY1   A0A158P454   A0A0K8TPM6   A0A0J7KN78   A0A224XH06   A0A0U3YU67   A0A151J8T2   A0A1B6M3J2   A0A151JVK1   A0A1Z1EBN7   A0A1B6C7B9   A0A067QR79   A0A2A3E1T0   V9IKZ0   A0A088AL09   Q4GXN2   A0A1A9WES3   A0A1Y1NAU7   A0A1A9UWU9   A0A1B0DNJ2   A0A0Q9WH39   A0A1A9ZW12   D3TQT3   A0A1L8DSE7   U5EMG6   A0A1A9YL61   A0A1B0C5G4   E2C451   A0A336LZX8   E2BZ60   A0A0M5J241   A0A0X7YC68   Q56FG6   A0A0Q9XHF5   A0A336KFF3   R4UMZ3   A0A026VYU9   A0A195CNX3   A0A151WVK2  

PDB

4V6W     E-value=8.11772e-114,     Score=1048

KEGG

692557    K02932 large subunit ribosomal protein L5e | (RefSeq) RpL5, L5; ribosomal protein L5

PATHWAY

03010    Ribosome - Bombyx mori (domestic silkworm)

GO

GO:0006412   GO:0005634   GO:0008097   GO:0003735   GO:0005840   GO:0000027   GO:0022625   GO:0022626   GO:0002181   GO:0003723   GO:0003677   GO:0005524   GO:0030983   GO:0006298   GO:0005622   GO:0016817   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

PANTHER

PTHR23410  

Subcellular location

Cytoplasm  
Nucleus  

Length:

299

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.38161

Exp number, first 60 AAs:

0

Total prob of N-in:

0.07344

outside

1  -  299

 

 

Pi

161.309649

Theta

181.575728

Tajima's D

-0.409482

CLR

0.543703

CSRT

0.258687065646718

Interpretation

Uncertain