Gene

KWMTBOMO08791  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007881

Annotation

NADH_dehydrogenase_[ubiquinone]_1_beta_subcomplex_subunit_8?_mitochondrial_[Papilio_xuthus]

Location

Bomo_Chr15(-):5398848-5401977      View in EpiBrowser

Full name

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial      

Alternative Name

Complex I-ASHI
NADH-ubiquinone oxidoreductase ASHI subunit

Location in the cell

Mitochondrial   Reliability : 2.735

CDS

ATGTCTTCGTTACTGAAAAGAGCTCTGTTCAACAACTCTCAATCCATAAGAAAAACGGCAGCTCTGTTTTGCAATGCCACTAGGAATCATTGGAATTACCAGTACCAACCTGGTCCTTATCCTAAAACACCAGAAGAACGGGCTGCAGCAGCTAAAAAATATGGAATGACTGTAGAGGAGTATACTCCCTATCCTGAAGATATGGGCTATGGTGATTATCCGAAGCTACCTGATATTGGTGAGGACTCCAAGGATCCTCATTATCCTTATGATAACCCGGAATTGAAGAGGAATTTCAATGAACCGTTGCACGCTACTGCAGAAATATTTGGTGGAGATCGCTGTGACATTAGCATAAGGCGAAGATTTTCACTGCTGCATCAATGGACTTGGTTTTTGGGTACTCTAGGAGGATTTGCTCTTCTAATGGTGTTTTTAGAAGACTATAAAATTGGAAGACCAGTTACAGCCAAGCAGATTCCTGGGCAGGGTGTTCATTACTTGTTCAGCCCAAATTAA

Protein

MSSLLKRALFNNSQSIRKTAALFCNATRNHWNYQYQPGPYPKTPEERAAAAKKYGMTVEEYTPYPEDMGYGDYPKLPDIGEDSKDPHYPYDNPELKRNFNEPLHATAEIFGGDRCDISIRRRFSLLHQWTWFLGTLGGFALLMVFLEDYKIGRPVTAKQIPGQGVHYLFSPN

Description

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subunit

Complex I is composed of 45 different subunits.

Similarity

Belongs to the complex I NDUFB8 subunit family.

Uniprot

H9JED4   A0A2H1W0K5   A0A2A4K5J6   A0A194PRB9   A0A194QMX2   I4DJB9   + More
A0A437AYN4   S4PU28   A0A212F0V9   A0A067QTB9   A0A2J7R5R0   D6X4J3   A0A0K8TP44   A0A2P8YY57   A0A1L8E0G3   A0A1B0DGQ9   A0A1L8DZX9   A0A1W4WMQ4   A0A182QFQ5   A0A182NCG4   A0A182XVY6   A0A182J9Q8   U5EVZ6   A0A2M4C243   A0A2M4C169   A0A0T6B4H5   A0A2M4ABA0   A0A1B0CDJ7   W5J8S5   A0A1B6DQG4   A0A2M3Z5F1   A0A2M3ZHG5   A0A182K8M2   A0A182MGK9   T1DNY6   A0A084VHB3   A0A2M4CIW0   B0W496   A0A2C9GRK5   A0A182UF20   Q7PCT5   A0A1Q3FKF4   Q17MK2   A0A182SRW1   A0A182G7Y6   A0A182PRJ5   A0A1I8JUE2   A0A1A9Z4V8   A0A1B0BFT4   A0A1B0FDZ4   A0A2M3Z4Z5   J3JZ66   A0A1A9Y1S3   A0A1A9VSE0   A0A0P4WK94   A0A182LH35   A0A423U8Q2   A0A1J1HXT8   A0A182UNE3   A0A182XBA2   U4U6W7   A0A182FKR8   A0A1L8EH50   A0A023EGZ9   A0A1L8EAG3   A0A1I8P7A0   A0A162Q156   A0A0P5XZP5   A0A0P6HRQ6   B4L5X7   A0A0N8BXI9   B4M7G9   A0A0P5P971   A0A0P5E3L4   A0A0K8VU85   A0A336LPW7   A0A0A1WJL8   A0A0P6DIC3   A0A0L0CCS1   E9GB70   A0A0P5EIN4   A0A0N8CPL7   A0A0P4X2H0   A0A0N8DA90   A0A1B6FY37   A0A0P6AX28   A0A0P5RFU8   W8BYF8   B4NPC8   A0A0P5UQY9   Q29JI8   B4H330   D0QWF3   A0A0C9PKI6   A0A2R7WCM3   A0A3B0K1A7   A0A0P5NTB6   Q9W3X7   A0A1W4VEL0   A0A0P5JPR3  

Pubmed

19121390    26354079    22651552    23622113    22118469    24845553    + More
18362917    19820115    26369729    29403074    25244985    20920257    23761445    24438588    12364791    14747013    17210077    17510324    26483478    22516182    23537049    20966253    24945155    17994087    25830018    26108605    21292972    24495485    15632085    19859648    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

BABH01002912    ODYU01005599    SOQ46608.1    NWSH01000105    PCG79515.1    KQ459596    + More
KPI95503.1    KQ461195    KPJ06694.1    AK401387    BAM18009.1    RSAL01000266    RVE43249.1    GAIX01011013    JAA81547.1    AGBW02011012    AGBW02009246    OWR47388.1    OWR51266.1    KK853541    KDR06880.1    NEVH01006990    PNF36160.1    KQ971380    EEZ97742.1    GDAI01001456    JAI16147.1    PYGN01000290    PSN49180.1    GFDF01002099    JAV11985.1    AJVK01033813    GFDF01002100    JAV11984.1    AXCN02000017    GANO01003191    JAB56680.1    GGFJ01009917    MBW59058.1    GGFJ01009916    MBW59057.1    LJIG01009955    KRT82046.1    GGFK01004750    MBW38071.1    AJWK01007944    ADMH02002044    ETN59783.1    GEDC01009387    JAS27911.1    GGFM01003000    MBW23751.1    GGFM01007164    MBW27915.1    AXCM01005544    GAMD01002450    JAA99140.1    ATLV01013150    KE524842    KFB37357.1    GGFL01000650    MBW64828.1    DS231836    EDS33181.1    APCN01002042    AAAB01008987    EAA01257.4    GFDL01006964    JAV28081.1    CH477205    EAT47922.1    JXUM01047265    JXUM01047266    JXUM01047267    KQ561512    KXJ78327.1    JXJN01013655    CCAG010023588    GGFM01002850    MBW23601.1    APGK01048488    BT128547    KB741112    AEE63504.1    ENN73804.1    GDRN01030558    JAI67545.1    QCYY01000448    ROT85085.1    CVRI01000035    CRK92829.1    KB632184    ERL89644.1    GFDG01000762    JAV18037.1    GAPW01005468    JAC08130.1    GFDG01003193    JAV15606.1    LRGB01000389    KZS19312.1    GDIP01066173    JAM37542.1    GDIQ01030737    JAN64000.1    CH933811    EDW06586.1    GDIQ01135147    JAL16579.1    CH940653    EDW62736.1    GDIQ01138041    JAL13685.1    GDIP01147311    JAJ76091.1    GDHF01015509    GDHF01009873    JAI36805.1    JAI42441.1    UFQT01000038    SSX18437.1    GBXI01015053    JAC99238.1    GDIQ01086165    JAN08572.1    JRES01000586    KNC30031.1    GL732537    EFX83377.1    GDIQ01269197    JAJ82527.1    GDIP01111311    JAL92403.1    GDIP01251350    JAI72051.1    GDIP01053527    JAM50188.1    GECZ01014667    JAS55102.1    GDIP01025357    JAM78358.1    GDIQ01120702    JAL31024.1    GAMC01000135    JAC06421.1    CH964291    EDW86368.1    GDIP01109608    JAL94106.1    CH379063    EAL32313.1    CH479205    EDW30723.1    FJ821027    ACN94665.1    GBYB01001538    JAG71305.1    KK854627    PTY17427.1    OUUW01000003    SPP78801.1    GDIQ01138042    JAL13684.1    AE014298    BT120041    AAF46185.1    ADA53580.1    GDIQ01196975    JAK54750.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    + More
UP000027135    UP000235965    UP000007266    UP000245037    UP000092462    UP000192223    UP000075886    UP000075884    UP000076408    UP000075880    UP000092461    UP000000673    UP000075881    UP000075883    UP000030765    UP000002320    UP000075840    UP000075902    UP000007062    UP000008820    UP000075901    UP000069940    UP000249989    UP000075885    UP000075900    UP000092445    UP000092460    UP000092444    UP000019118    UP000092443    UP000078200    UP000075882    UP000283509    UP000183832    UP000075903    UP000076407    UP000030742    UP000069272    UP000095300    UP000076858    UP000009192    UP000008792    UP000037069    UP000000305    UP000007798    UP000001819    UP000008744    UP000268350    UP000000803    UP000192221   

PRIDE

H9JED4    Q9W3X7   

Pfam

PF05821   NDUF_B8        + More
PF00400   WD40
PF01632   Ribosomal_L35p

Interpro

IPR008699   NDUFB8        + More
IPR016551   Ndufb8_metazoa       
IPR020472   G-protein_beta_WD-40_rep       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR037866   Swd3/WDR5       
IPR017986   WD40_repeat_dom       
IPR001680   WD40_repeat       
IPR037229   Ribosomal_L35_sf       
IPR019338   Ribosomal-L35_mit       
IPR021137   Ribosomal_L35       

SUPFAM

SSF50978   SSF50978        + More
SSF143034   SSF143034       

Gene 3D

2.130.10.10    

ProteinModelPortal

H9JED4   A0A2H1W0K5   A0A2A4K5J6   A0A194PRB9   A0A194QMX2   I4DJB9   + More
A0A437AYN4   S4PU28   A0A212F0V9   A0A067QTB9   A0A2J7R5R0   D6X4J3   A0A0K8TP44   A0A2P8YY57   A0A1L8E0G3   A0A1B0DGQ9   A0A1L8DZX9   A0A1W4WMQ4   A0A182QFQ5   A0A182NCG4   A0A182XVY6   A0A182J9Q8   U5EVZ6   A0A2M4C243   A0A2M4C169   A0A0T6B4H5   A0A2M4ABA0   A0A1B0CDJ7   W5J8S5   A0A1B6DQG4   A0A2M3Z5F1   A0A2M3ZHG5   A0A182K8M2   A0A182MGK9   T1DNY6   A0A084VHB3   A0A2M4CIW0   B0W496   A0A2C9GRK5   A0A182UF20   Q7PCT5   A0A1Q3FKF4   Q17MK2   A0A182SRW1   A0A182G7Y6   A0A182PRJ5   A0A1I8JUE2   A0A1A9Z4V8   A0A1B0BFT4   A0A1B0FDZ4   A0A2M3Z4Z5   J3JZ66   A0A1A9Y1S3   A0A1A9VSE0   A0A0P4WK94   A0A182LH35   A0A423U8Q2   A0A1J1HXT8   A0A182UNE3   A0A182XBA2   U4U6W7   A0A182FKR8   A0A1L8EH50   A0A023EGZ9   A0A1L8EAG3   A0A1I8P7A0   A0A162Q156   A0A0P5XZP5   A0A0P6HRQ6   B4L5X7   A0A0N8BXI9   B4M7G9   A0A0P5P971   A0A0P5E3L4   A0A0K8VU85   A0A336LPW7   A0A0A1WJL8   A0A0P6DIC3   A0A0L0CCS1   E9GB70   A0A0P5EIN4   A0A0N8CPL7   A0A0P4X2H0   A0A0N8DA90   A0A1B6FY37   A0A0P6AX28   A0A0P5RFU8   W8BYF8   B4NPC8   A0A0P5UQY9   Q29JI8   B4H330   D0QWF3   A0A0C9PKI6   A0A2R7WCM3   A0A3B0K1A7   A0A0P5NTB6   Q9W3X7   A0A1W4VEL0   A0A0P5JPR3  

PDB

5GUP     E-value=1.0272e-24,     Score=276

KEGG

101737782    K03964 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 | (RefSeq) NADH dehydrogenase [ub

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0005739   GO:0008137   GO:0005747   GO:0006120   GO:0005840   GO:0003735   GO:0006412   GO:0003954   GO:0003707   GO:0005634   GO:0003700   GO:0008270   GO:0043565   GO:0016876   GO:0043039  

PANTHER

PTHR12840   PTHR22847:SF516   PTHR15909  

Subcellular location

Mitochondrion inner membrane  

Length:

172

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

20.14017

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.38173

outside

1  -  128

TMhelix

129  -  146

inside

147  -  172

 

 

Pi

176.646136

Theta

138.788549

Tajima's D

1.208923

CLR

0

CSRT

0.715914204289785

Interpretation

Uncertain