Gene

KWMTBOMO08782

Pre Gene Modal

BGIBMGA005903

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr15(+):5269099-5272972      View in EpiBrowser

Full name

Integrin beta       + More
Guanylate cyclase      

Location in the cell

Nuclear   Reliability : 4.077

CDS

ATGGATAAAATTACAAGTTTGTTGGAATCTATTCAAATTGAACAAAAACTCCAAAAGGAAGAGATGAGAGAAATGCAAAAAAATATAACAAAGAGTATTAACAATAACATAAATGAAAAATTTAACGAAATGGATCTCAAGTACAAACACTTGGTTGAAAAATTGGATATTCAAGAAAAACAAATAGATTACTTAGAGAGAGAAAACAAAAGGAGAAATTTAGTTTTTTTCGGAATAGAAGAAGAAGAGAGAAGTTACTTCCAGCTTTATACAAAAGTAACTTACATAATAACGATGAACATGAAGTTATCTTGTGAGAAATACGATATAGAGAACATTAAACGTATCGGTAAGAAAGGAAACAAAGTTAGGCCCGTTATAGTAACCCTTACAACACTAGGAAAAAAGATAGAGATCCTGAAGAATAAAAAATCTCTAGCAAGCACGTCATATTATATACAAGAAGATTATCCTAAAAAAGTTTTGGAGACAAGAAAATCTTTGAAAGTTACAGTGGAAGAACTCAGACAGGAAGGAAAGGCTGCAATCATTAAATACGATAAGTTAATAATTTTAGAGGATAAACTACCAAAACAACATCAACATTCCAAAAAGAGAATGCTCACACCGTCTCCAGTTACTCAAAATAACGCAAAATATAAAAAAAATAGAGAGCAGAATAAGTTAAGCAGGTCAGATATAGCTAGTTTCTTCGTTCCACAAACCGACAATGAGAAGCCCTCTCAGAAAATAAAAATAGACGTATTAGGCTTGGCAGAAGTCAGGAGAATGGGATGCAATATTGAAGAACATGAAGATTATATCTTCTGCTACAAAGGAGAAACGCCAGGCTTGTATGGTGTGGGCTTCTTAGTTAAGAAAGAGCATAAAAACAAGATACTAAGCTTCTCAGGCCTATCCGAACGCGTGGATATGCTGCAGATTAAATGTAACAATACGACACTGTCAATAATACAAGCCTACGCCCCTACAGAGAGAGCACCAGAGGAGGATATCAATCTATTCTACGAAACTCTAGAAACAGCGCTAAGCCAGGCAGGCAGACATGTTCTTCTTCTCGGCGACTTTAACGCTCAGGTAGGTCAGACAAGCACGAACGATAGTATAGTCATGGGAAAATTCGGATACGGAAAACGAAGCGAGAGAGGGGAAAGGCTTGTGCAATATGCCTTGGAAAACAAACTATCGATCATGAATACATTTTTTAAAGCCAGGAAAAATCGTAAATGGACATGGCTGTCTCCCGATGAAAATACTAAAAATCAAGTAGATTTTATTCTATCGAACGAACGAAAAAAGATAAGGAAGTTAGATGTTCTCAACGCCTTAGGATTTAGATCAGACCATCGCCTAGTCAGAGTTACATACATGCTAAAAAAAGAAAAGGAAAGCAGAACAACATTTAAATCACAACCTAAGCCCCTCAAAACAGAAGAAGATATTAGCTGCTATTTGCAGAACTTAAAACAAAACATACAAGAATTGAACACACAAAACGACGAACACGACGTACAAACATACTACAATACATTAGAAAATGTTATTAATAAGAGCATGCCATCAAAAAAGAAGGAGCCAAAAGTAGATACTGTTGGAAAAATTCTCAGTAAACATACACTGGATATGCTCAGAAAACGAACAGAACTAGTACAAAAAAAACCAAAAACTGAGGAAATGAAAAAGGAATTAAGTACTTTGTATAAATCAACAAGCAAGGCCATAAAAAAAGATTACCAAAATCATAGAAATAGAATAATAGAGGAGAACCTACATAAATTTAGAAGTTCCAAAAGAGCATACAAACAGCTAACAACACACAAAAACTGGATCCAAACCCTAAAAACAAGCACCAAAGAGACCAAAACTAGAGACAGTGTAATAAATTGTGCTACAGAATTTTTTAAAGTACTATATGGCATGAAAGCTGACATCTCTTCGAGTTCAATTGCTTATTATTCTAGTAAGGACTGCAAGTATTGTAAAATCGCTTCGGAGAAGGTTGATATAGCACCAATAAGCGGTAAGGAAATTATCAAACACATTAAAAAGATGAAGCAAGACAAAAGCCCAGGACCCGATGGTTTACAAAATGAGGCTATAAAGACTGGTTCTACTTTGTTAATTCACCCTCTTACTTACTTGTTTAACAAAGTACTCGATACTGGGGAAGTGCCAGAACAGTGGAAAAGATCCGATATAATCTTACTGCTCAAAAAGGGAGATCCAAATGACATAGGCAACTACAGGCCTATTAGCCTCCTTTCGAGTATGTACAAGCTATTCACATCAATTTTACAAAGCAGAATGACTCCAAAAATTGATGAACACCAGTCGATCGAACAAGCAGGTTTCCGTTCGGGTTTTTCGACAATAGATCATATACATGTTATACAACAAGTTATAGAGAAATATAAAGAGTTCAATAGACCACTGTACATAGCTTTCATCGACTATGCTAAAGCCTTCGATACAATCGTACATAATTTCATATGGAAAGCCCTAGATAAATGTCACGTTCATGATAAATACATAAAAATATTAAAAAACATCTATGATGGAAGTATCAGCAGAGTCAAACTGGAAAAACGGGGAGAGGACATAAAAATCTGCCAAGGAGTAAGACAGGGTGATCCTTTGTCGCCTAAGCTGTTTATAGCAGTACTACAGCTTATCTTTGAAAATGTACACTGGCCATCGAACGGAATCAAAGTAAATGGGAAGCGACTTACACATTTGAGATTTGCTGATGATATCGTTCTCTTCGCTGAAACAAACGAAAAACTCGAAAAAATGATAAATATTTTAAGCGAGGAAAGCGAAAAAGTCGGTCTCAAAATGAACCAAGACAAAACCAAAGTAATGACAAACAGTAGTGCTGATAAAATCAGCTTGTATGGCAAACCGTTAGAGTACGTAAACAGCTATATATATCTCGGAAAATTAATTTCATTTAAAGACAACAACGATGAAGAAGAAGTCGAACGCCGAATCAATATAACTTGGAGAAAATTCTGGAGCTTAAAGGAAATTCTAAAAGGGTCCTTCCCTCTTCATCTGAAAAAGACTGTGATGGATACCTGTATTCTTCCGACTCTCTTATATGGGTGCCAAACATGGACTTACAACACAAAAATAAAAACAAAATTAGCGACCTGTCAGAAAGCGATGGAAAGAAGTATATTGAATATAAGAAAAATACAAAGGATAAGAAGCGAATACATTAGAGAAAAAACAAAGCTGATAGATGCTCTCAGGTACGCTCTGACACAAAAGTGGCGCTGGGCAGGACATCTTGCGAGATATACGGATAAAAGATGGACATTAGAAATTACAACATGGGAAGGACCAGCGGGCAAAAGAAGAAGAGGACGACCAAGAAGCAGATGGATCGACGAAATAACAGCAGCAACTGGAAAAGAATGGAGAAACAAAGCCAAGGATAGGGAAGAGTGGAGCAAGCTGGAGGAGGCCTATACCCGAATGGGGTTTCAAGCACAAGTTTATATTTAA

Protein

MDKITSLLESIQIEQKLQKEEMREMQKNITKSINNNINEKFNEMDLKYKHLVEKLDIQEKQIDYLERENKRRNLVFFGIEEEERSYFQLYTKVTYIITMNMKLSCEKYDIENIKRIGKKGNKVRPVIVTLTTLGKKIEILKNKKSLASTSYYIQEDYPKKVLETRKSLKVTVEELRQEGKAAIIKYDKLIILEDKLPKQHQHSKKRMLTPSPVTQNNAKYKKNREQNKLSRSDIASFFVPQTDNEKPSQKIKIDVLGLAEVRRMGCNIEEHEDYIFCYKGETPGLYGVGFLVKKEHKNKILSFSGLSERVDMLQIKCNNTTLSIIQAYAPTERAPEEDINLFYETLETALSQAGRHVLLLGDFNAQVGQTSTNDSIVMGKFGYGKRSERGERLVQYALENKLSIMNTFFKARKNRKWTWLSPDENTKNQVDFILSNERKKIRKLDVLNALGFRSDHRLVRVTYMLKKEKESRTTFKSQPKPLKTEEDISCYLQNLKQNIQELNTQNDEHDVQTYYNTLENVINKSMPSKKKEPKVDTVGKILSKHTLDMLRKRTELVQKKPKTEEMKKELSTLYKSTSKAIKKDYQNHRNRIIEENLHKFRSSKRAYKQLTTHKNWIQTLKTSTKETKTRDSVINCATEFFKVLYGMKADISSSSIAYYSSKDCKYCKIASEKVDIAPISGKEIIKHIKKMKQDKSPGPDGLQNEAIKTGSTLLIHPLTYLFNKVLDTGEVPEQWKRSDIILLLKKGDPNDIGNYRPISLLSSMYKLFTSILQSRMTPKIDEHQSIEQAGFRSGFSTIDHIHVIQQVIEKYKEFNRPLYIAFIDYAKAFDTIVHNFIWKALDKCHVHDKYIKILKNIYDGSISRVKLEKRGEDIKICQGVRQGDPLSPKLFIAVLQLIFENVHWPSNGIKVNGKRLTHLRFADDIVLFAETNEKLEKMINILSEESEKVGLKMNQDKTKVMTNSSADKISLYGKPLEYVNSYIYLGKLISFKDNNDEEEVERRINITWRKFWSLKEILKGSFPLHLKKTVMDTCILPTLLYGCQTWTYNTKIKTKLATCQKAMERSILNIRKIQRIRSEYIREKTKLIDALRYALTQKWRWAGHLARYTDKRWTLEITTWEGPAGKRRRGRPRSRWIDEITAATGKEWRNKAKDREEWSKLEEAYTRMGFQAQVYI

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the integrin beta chain family.

Feature

chain  Integrin beta

Uniprot

A0A2H1WF27   D7F177   D7F178   D7F179   A0A2H1VS24   A0A2W1BZV1   + More
D7F176   A0A069DZM5   A0A023EXV2   D7F157   D7F165   D7F159   D7F164   D7F158   D7F160   A0A437BHD1   D7F166   A0A016S1D2   A0A016SG46   A0A016TK11   A0A016W4R1   A0A016WPY4   A0A0K0FAW8   A0A016WCB8   A0A016ULU9   A0A016V419   A0A016SX67   A0A016SGC3   A0A0N5C0B1   A0A016V6A2   A0A016VEC1   A0A016VCD9   A0A016UN79   A0A016T590   A0A016VBP7   A0A016VCU3   A0A2W5U8K4   A0A023EWU8   A0A016RV73   A0A016RUR3   G0MZ46   A0A016SLV8   A0A0P4VWD0   A0A016TNH6   A0A016TNS4   A0A016TNL1   A0A016TMT8   A0A016U784   A0A016RRX8   A0A016S403   A0A016VCK8   E3NC15   A0A016V4Q8   A0A069DX96   A0A016T7J7   E3MH09   A0A016THC6   A0A016WA79   A0A016VVN3   A0A016S795   A0A016T4C4   A0A016WFS9   A0A016WUN2   A0A016S5B2   A0A016WHK1   A0A016VV43   A0A016SY13   A0A016W1X2   A0A016VT25   A0A016TK92   A0A016U6B7   A0A016WYN9   A0A016SCL7   A0A016SCZ8   A0A016VLP0   A0A016UJS4   A0A016U123   A0A016WQM8   A0A016TQJ1   A0A016V007   A0A016X207   A0A016U4H4   A0A016SXL6   A0A016WPX9   A0A016S7F6   A0A016S6J0   A0A016T636   A0A016SCT9   A0A016SPR9  

EC Number

4.6.1.2

Pubmed

20470440    28756777    26334808    25474469    25730766    27129103    + More

EMBL

ODYU01008249    SOQ51673.1    FJ265562    ADI61830.1    FJ265563    ADI61831.1    + More
FJ265564    ADI61832.1    ODYU01004088    SOQ43598.1    KZ149907    PZC78256.1    FJ265561    ADI61829.1    GBGD01000380    JAC88509.1    GBBI01004876    JAC13836.1    FJ265542    ADI61810.1    FJ265550    ADI61818.1    FJ265544    ADI61812.1    FJ265549    ADI61817.1    FJ265543    ADI61811.1    FJ265545    ADI61813.1    RSAL01000057    RVE49824.1    FJ265551    ADI61819.1    JARK01001655    EYB84321.1    JARK01001565    EYB89683.1    JARK01001676    JARK01001446    JARK01001433    EYB83199.1    EYC01126.1    EYC02928.1    JARK01001337    EYC34625.1    JARK01000173    EYC41342.1    JARK01000388    EYC37469.1    JARK01001370    EYC16150.1    JARK01001354    EYC21986.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    JARK01001568    EYB89432.1    JARK01001353    EYC22263.1    JARK01001348    EYC25048.1    EYC25050.1    EYC16376.1    JARK01001473    EYB97806.1    EYC25049.1    EYC25046.1    QFQQ01000179    PZR20596.1    GBBI01004877    JAC13835.1    JARK01001700    JARK01001393    EYB82228.1    EYC10181.1    JARK01001711    EYB81734.1    GL379822    EGT48339.1    JARK01001543    EYB91356.1    GDKW01001596    JAI54999.1    JARK01001424    EYC04315.1    EYC04317.1    EYC04316.1    EYC04314.1    JARK01001389    EYC11015.1    JARK01001730    EYB81048.1    JARK01001639    EYB85201.1    EYC25145.1    DS268591    EFO92565.1    EYC21713.1    GBGD01000453    JAC88436.1    JARK01001736    JARK01001462    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    DS268444    EFP01729.1    JARK01001438    EYC02111.1    JARK01000460    EYC36749.1    JARK01001340    EYC30828.1    JARK01001621    EYB86109.1    JARK01001475    EYB97550.1    JARK01000302    EYC38674.1    JARK01000109    EYC42952.1    JARK01001626    EYB85833.1    JARK01000314    EYC38488.1    EYC31464.1    JARK01001497    EYB95322.1    EYC33297.1    EYC30744.1    JARK01001432    EYC03125.1    EYC10874.1    JARK01000063    EYC44387.1    JARK01001628    JARK01001583    JARK01001528    JARK01001506    JARK01001470    JARK01001467    JARK01001463    JARK01001457    JARK01001420    JARK01001403    JARK01001371    JARK01001369    JARK01001360    JARK01001349    JARK01000603    JARK01000080    EYB85741.1    EYB88438.1    EYB92544.1    EYB94540.1    EYB98080.1    EYB98468.1    EYB98899.1    EYB99568.1    EYC03088.1    EYC05014.1    EYC08153.1    EYC15852.1    EYC16408.1    EYC19456.1    EYC22445.1    EYC24734.1    EYC24778.1    EYC24866.1    EYC33488.1    EYC35672.1    EYC43798.1    JARK01001581    EYB88505.1    JARK01001344    EYC28216.1    JARK01001372    EYC15614.1    JARK01001401    EYC08686.1    JARK01000165    EYC41537.1    JARK01001421    EYC04912.1    JARK01001357    EYC20551.1    JARK01000008    EYC46079.1    EYC10025.1    EYB95049.1    JARK01000161    EYC41641.1    JARK01001612    EYB86585.1    JARK01001618    EYB86258.1    JARK01000204    EYB98081.1    EYC40601.1    JARK01001582    EYB88498.1    JARK01001531    EYB92324.1   

Proteomes

UP000283053    UP000024635    UP000035680    UP000046392    UP000008068    UP000008281    + More

PRIDE

D7F177    D7F178    D7F179    D7F176    D7F157    D7F165    + More
D7F159    D7F164    D7F158    D7F160    D7F166   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF00362   Integrin_beta
PF03372   Exo_endo_phos
PF01094   ANF_receptor
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR032695   Integrin_dom_sf       
IPR036465   vWFA_dom_sf       
IPR015812   Integrin_bsu       
IPR002035   VWF_A       
IPR002369   Integrin_bsu_VWA       
IPR029052   Metallo-depent_PP-like       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR001170   ANPR/GUC       
IPR001054   A/G_cyclase       
IPR028082   Peripla_BP_I       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       

SUPFAM

SSF56219   SSF56219        + More
SSF53300   SSF53300       
SSF69179   SSF69179       
SSF53822   SSF53822       
SSF55073   SSF55073       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.40.50.410     3.60.21.10     3.30.70.1230    

ProteinModelPortal

A0A2H1WF27   D7F177   D7F178   D7F179   A0A2H1VS24   A0A2W1BZV1   + More
D7F176   A0A069DZM5   A0A023EXV2   D7F157   D7F165   D7F159   D7F164   D7F158   D7F160   A0A437BHD1   D7F166   A0A016S1D2   A0A016SG46   A0A016TK11   A0A016W4R1   A0A016WPY4   A0A0K0FAW8   A0A016WCB8   A0A016ULU9   A0A016V419   A0A016SX67   A0A016SGC3   A0A0N5C0B1   A0A016V6A2   A0A016VEC1   A0A016VCD9   A0A016UN79   A0A016T590   A0A016VBP7   A0A016VCU3   A0A2W5U8K4   A0A023EWU8   A0A016RV73   A0A016RUR3   G0MZ46   A0A016SLV8   A0A0P4VWD0   A0A016TNH6   A0A016TNS4   A0A016TNL1   A0A016TMT8   A0A016U784   A0A016RRX8   A0A016S403   A0A016VCK8   E3NC15   A0A016V4Q8   A0A069DX96   A0A016T7J7   E3MH09   A0A016THC6   A0A016WA79   A0A016VVN3   A0A016S795   A0A016T4C4   A0A016WFS9   A0A016WUN2   A0A016S5B2   A0A016WHK1   A0A016VV43   A0A016SY13   A0A016W1X2   A0A016VT25   A0A016TK92   A0A016U6B7   A0A016WYN9   A0A016SCL7   A0A016SCZ8   A0A016VLP0   A0A016UJS4   A0A016U123   A0A016WQM8   A0A016TQJ1   A0A016V007   A0A016X207   A0A016U4H4   A0A016SXL6   A0A016WPX9   A0A016S7F6   A0A016S6J0   A0A016T636   A0A016SCT9   A0A016SPR9  

PDB

6AR3     E-value=0.000718051,     Score=106

KEGG

101741296    no KO assigned | (RefSeq) uncharacterized LOC101741296

GO

GO:0004519   GO:0003964   GO:0005524   GO:0004672   GO:0004383   GO:0016021   GO:0035556  

PANTHER

PTHR10082  

Subcellular location

Membrane  

Length:

1176

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02454

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00001

outside

1  -  1176

 

 

Pi

258.586318

Theta

165.278755

Tajima's D

2.019583

CLR

26.595369

CSRT

0.885755712214389

Interpretation

Uncertain