Gene

KWMTBOMO08776  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007889

Annotation

eukaryotic_translation_initiation_factor_3_subunit_I_[Bombyx_mori]

Location

Bomo_Chr15(-):4997070-4999258      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit I      

Alternative Name

Eukaryotic translation initiation factor 3 subunit 2
TRIP-1 homolog
eIF-3-beta

Location in the cell

Cytoplasmic   Reliability : 2.152

CDS

ATGAAACCTCTTATGCTGCAAGGGCACCAGCGTGCCATCACACAGATCAAATATAACCGCGAGGGTGACTTGCTCTTCTCCGCCGCTAAAGATTCAAAACCAAATGTTTGGTGGTCACTGAACGGCGAACGTCTTGGCACTTTCAACGGCCACGGTGGTGTAATATGGTGCCTTGACGTCGACTGGCAGTCAATTAATCTCATCACAGGTGGTGGCGACAGTTCCTGCAGGTTATGGGATCTGGAGACAGGCAAGAATATTGCAACACTCAAATCCAACTCTTCTGTAAGAACATGCAACTTCAGCTATAGTGCATATCAAGCTGCTTATACCACTGACAAAGCTATGGGACACCCTTGTGAGGTGTTCGTTATTGATACAAGAACAATTGATGAAACAGTGTCAGGTCAAGCTCCTATTTTAAAATGGGAAATCACAGATTCAAAGGTTACTTCAATGATTTGGGGTTCTTTAGATGAGACAATTATCACTGGTCATGAAGCTGGTGACCTTATACAATGGGATCTGAGGACTGGTAAAAAAATCCACTCTGTTAAAGAGCATACCCACCAAATCACCGATATGCAACTTTCTCGTGACGGCACAATGTTTGTAACTGCTTCCAAGGATCATACTGCTAAGTTATTTGACACTAACTCATTAGAACTTCTTAAAGAATACAAGACAGAGAGACCTGTAAATTCTGCTGCTCTCAGTCCAATCCTTGATCATGTTGTACTTGGTGGTGGTCAAGATGCTATGGAAGTGACAACCACATCAACCAGACAGGGTAAATTCGATGCTCGTTTCTTCCACTTAGTATTTGAAGAGGAGTTTGGCCGAGTGAAAGGTCACTTTGGTCCTATCAACAGTTTGGCTTTCCATCCAGATGGAAAGTCCTATGCTTCCGGAGGTGAAGATGGTTATGTTCGTGTTCATAACTTTGATCAATCTTACTTTGACTACACTTTCGATTACAATAGGGAGTAG

Protein

MKPLMLQGHQRAITQIKYNREGDLLFSAAKDSKPNVWWSLNGERLGTFNGHGGVIWCLDVDWQSINLITGGGDSSCRLWDLETGKNIATLKSNSSVRTCNFSYSAYQAAYTTDKAMGHPCEVFVIDTRTIDETVSGQAPILKWEITDSKVTSMIWGSLDETIITGHEAGDLIQWDLRTGKKIHSVKEHTHQITDMQLSRDGTMFVTASKDHTAKLFDTNSLELLKEYKTERPVNSAALSPILDHVVLGGGQDAMEVTTTSTRQGKFDARFFHLVFEEEFGRVKGHFGPINSLAFHPDGKSYASGGEDGYVRVHNFDQSYFDYTFDYNRE

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix.

Similarity

Belongs to the eIF-3 subunit I family.

Keywords

Complete proteome   Cytoplasm   Initiation factor   Protein biosynthesis   Reference proteome   Repeat   WD repeat  

Feature

chain  Eukaryotic translation initiation factor 3 subunit I

Uniprot

Q1HPW4   H9JEE2   A0A437AYL7   I4DJJ9   A0A3G1T1N1   A0A212EIJ3   + More
A0A194PPW9   A0A194QNX8   A0A2A4K5I6   S4PM59   A0A0L7LKM6   A0A1W4WKK9   J3JWH5   D6WIX1   A0A182GS55   U5EMH0   A0A1Y1M9M8   A0A1B0D0M2   A0A336MS18   A0A1B0CGV0   A0A1L8DZI2   A0A151I605   E9I9N8   B2ZPG7   A0A182NI99   Q16K15   A0A182Q7M7   A0A1B6FG39   A0A1A9X8B7   A0A1A9V9Z4   D3TRV5   A0A182JUN0   A0A182INM2   A0A026WGB0   A0A182WBQ9   A0A182V9A2   A0A182UBW0   A0A182X4I8   A0A182I4I5   Q7PP77   A0A182MJP2   A0A1B0AIS3   A0A0L0CG30   A0A195CKS1   A0A151X5D1   A0A182Y2K0   A0A1A9WAK2   E2BUC0   A0A158NX77   F4WMK0   A0A182R955   A0A195EV97   A0A182S8C2   A0A2P0XIF4   W8BZJ2   V9IM01   A0A088A549   A0A182PMU6   A0A151J0J7   B4I195   O02195   A0A0P5G940   A0A0M4E3J5   A0A0P6G963   B3N4C7   A0A0A1WMS4   T1PC07   A0A1Q3F8Z7   A0A0J9QWT8   B4Q354   A0A034WL41   A0A0C9PIP3   A0A0L7R8G3   A0A1B6LWD1   B4JB43   Q29L19   B4GSH1   B4N0L0   A0A1B6HZ94   A0A0P5SRB4   B0XFT7   A0A1W4UVL2   A0A411G726   A0A2A3E5B2   B4KGX9   A0A1J1IWU5   A0A3B0K8J1   A0A3L8DEB8   A0A0K8UJS6   E9GJP1   B3MVL6   A0A2S2R973   A0A1I8P3I1   A0A1L8EEB7   E2ABF7   E2BUC1   A0A0N7ZGP1   B4NW98   B4LUA5   A0A0N0BIF6  

Pubmed

19121390    22651552    22118469    26354079    23622113    26227816    + More
22516182    23537049    18362917    19820115    26483478    28004739    21282665    17510324    20353571    24508170    12364791    26108605    25244985    20798317    21347285    21719571    24495485    17994087    10731132    12537572    12537569    17392269    25830018    25315136    22936249    25348373    15632085    30249741    21292972   

EMBL

DQ443288    BABH01002941    RSAL01000268    RVE43219.1    AK401467    BAM18089.1    + More
MG992458    AXY94896.1    AGBW02014626    OWR41312.1    KQ459596    KPI95491.1    KQ461195    KPJ06680.1    NWSH01000105    PCG79505.1    GAIX01003730    JAA88830.1    JTDY01000831    KOB75741.1    APGK01018009    BT127593    KB740064    KB632165    AEE62555.1    ENN81757.1    ERL89282.1    KQ971337    EEZ99635.1    JXUM01016963    KQ560471    KXJ82240.1    GANO01001034    JAB58837.1    GEZM01038244    JAV81698.1    AJVK01009966    UFQT01002377    SSX33334.1    AJWK01011592    GFDF01002392    JAV11692.1    KQ976410    KYM90763.1    GL761846    EFZ22632.1    EU678971    ACD65081.1    CH477981    AXCN02000878    GECZ01020591    JAS49178.1    CCAG010018118    EZ424157    ADD20433.1    KK107231    EZA54998.1    APCN01002315    AAAB01008960    AXCM01003402    JRES01000438    KNC31205.1    KQ977642    KYN01052.1    KQ982519    KYQ55499.1    GL450630    EFN80704.1    ADTU01029411    GL888217    EGI64611.1    KQ981954    KYN32185.1    KY661315    AVA17402.1    GAMC01001783    JAC04773.1    JR052537    AEY61717.1    KQ980629    KYN15004.1    CH480820    U90930    AE014134    AY118527    GDIQ01247813    GDIQ01184125    JAK03912.1    CP012523    ALC38196.1    GDIQ01241008    GDIQ01223462    GDIQ01049378    GDIQ01047880    LRGB01001363    JAN46857.1    KZS12157.1    CH954177    GBXI01014564    JAC99727.1    KA646224    AFP60853.1    GFDL01011001    JAV24044.1    CM002910    KMY88184.1    CM000361    GAKP01004092    JAC54860.1    GBYB01000813    JAG70580.1    KQ414633    KOC67051.1    GEBQ01017309    GEBQ01012037    JAT22668.1    JAT27940.1    CH916368    CH379061    CH479189    CH963920    GECU01027717    JAS79989.1    GDIQ01091958    JAL59768.1    DS232960    DS233035    MH365901    QBB01710.1    KZ288364    PBC26885.1    CH933807    CVRI01000063    CRL04631.1    OUUW01000006    SPP81946.1    QOIP01000009    RLU18636.1    GDHF01025370    JAI26944.1    GL732548    EFX80147.1    CH902624    GGMS01017332    MBY86535.1    GFDG01001783    JAV17016.1    GL438246    EFN69223.1    EFN80705.1    GDIP01247209    JAI76192.1    CM000157    CH940649    KQ435729    KOX77634.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053268    UP000053240    UP000218220    + More
UP000037510    UP000192223    UP000019118    UP000030742    UP000007266    UP000069940    UP000249989    UP000092462    UP000092461    UP000078540    UP000075884    UP000008820    UP000075886    UP000092443    UP000078200    UP000092444    UP000075881    UP000075880    UP000053097    UP000075920    UP000075903    UP000075902    UP000076407    UP000075840    UP000007062    UP000075883    UP000092445    UP000037069    UP000078542    UP000075809    UP000076408    UP000091820    UP000008237    UP000005205    UP000007755    UP000075900    UP000078541    UP000075901    UP000005203    UP000075885    UP000078492    UP000001292    UP000000803    UP000092553    UP000076858    UP000008711    UP000095301    UP000000304    UP000053825    UP000001070    UP000001819    UP000008744    UP000007798    UP000002320    UP000192221    UP000242457    UP000009192    UP000183832    UP000268350    UP000279307    UP000000305    UP000007801    UP000095300    UP000000311    UP000002282    UP000008792    UP000053105   

PRIDE

Q1HPW4    H9JEE2    B4I195    O02195    B3N4C7    B4Q354    + More
B4JB43    Q29L19    B4GSH1    B4N0L0    B4KGX9    B3MVL6    B4NW98    B4LUA5   

Pfam

PF00400   WD40        + More
PF12894   ANAPC4_WD40

Interpro

IPR036322   WD40_repeat_dom_sf        + More
IPR027525   eIF3i       
IPR019775   WD40_repeat_CS       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       
IPR024977   Apc4_WD40_dom       
IPR020472   G-protein_beta_WD-40_rep       

SUPFAM

SSF50978   SSF50978       

Gene 3D

2.130.10.10    

ProteinModelPortal

Q1HPW4   H9JEE2   A0A437AYL7   I4DJJ9   A0A3G1T1N1   A0A212EIJ3   + More
A0A194PPW9   A0A194QNX8   A0A2A4K5I6   S4PM59   A0A0L7LKM6   A0A1W4WKK9   J3JWH5   D6WIX1   A0A182GS55   U5EMH0   A0A1Y1M9M8   A0A1B0D0M2   A0A336MS18   A0A1B0CGV0   A0A1L8DZI2   A0A151I605   E9I9N8   B2ZPG7   A0A182NI99   Q16K15   A0A182Q7M7   A0A1B6FG39   A0A1A9X8B7   A0A1A9V9Z4   D3TRV5   A0A182JUN0   A0A182INM2   A0A026WGB0   A0A182WBQ9   A0A182V9A2   A0A182UBW0   A0A182X4I8   A0A182I4I5   Q7PP77   A0A182MJP2   A0A1B0AIS3   A0A0L0CG30   A0A195CKS1   A0A151X5D1   A0A182Y2K0   A0A1A9WAK2   E2BUC0   A0A158NX77   F4WMK0   A0A182R955   A0A195EV97   A0A182S8C2   A0A2P0XIF4   W8BZJ2   V9IM01   A0A088A549   A0A182PMU6   A0A151J0J7   B4I195   O02195   A0A0P5G940   A0A0M4E3J5   A0A0P6G963   B3N4C7   A0A0A1WMS4   T1PC07   A0A1Q3F8Z7   A0A0J9QWT8   B4Q354   A0A034WL41   A0A0C9PIP3   A0A0L7R8G3   A0A1B6LWD1   B4JB43   Q29L19   B4GSH1   B4N0L0   A0A1B6HZ94   A0A0P5SRB4   B0XFT7   A0A1W4UVL2   A0A411G726   A0A2A3E5B2   B4KGX9   A0A1J1IWU5   A0A3B0K8J1   A0A3L8DEB8   A0A0K8UJS6   E9GJP1   B3MVL6   A0A2S2R973   A0A1I8P3I1   A0A1L8EEB7   E2ABF7   E2BUC1   A0A0N7ZGP1   B4NW98   B4LUA5   A0A0N0BIF6  

PDB

5K0Y     E-value=1.40672e-119,     Score=1098

KEGG

732970    K03246 translation initiation factor 3 subunit I | (RefSeq) eIF3i; Eukaryotic translation initiation

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0033290   GO:0001732   GO:0005852   GO:0003743   GO:0016282   GO:0016301   GO:0006413   GO:0005515   GO:0005737   GO:0016020   GO:0005509   GO:0050793   GO:0003676   GO:0016876   GO:0043039  

Subcellular location

Cytoplasm  

Length:

329

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00037

Exp number, first 60 AAs:

0.0002

Total prob of N-in:

0.00948

outside

1  -  329

 

 

Pi

173.576177

Theta

138.298108

Tajima's D

0.926833

CLR

0

CSRT

0.638118094095295

Interpretation

Uncertain