Gene

KWMTBOMO08746

Annotation

Lipase_[Operophtera_brumata]

Location

Bomo_Chr15(-):4119930-4121330      View in EpiBrowser

Full name

Lipase      

Location in the cell

PlasmaMembrane   Reliability : 2.373

CDS

ATGTATCATTTATTGTGTGTTAAAATAATATTAACGATTTTATTCTTGAAGATTTGTCACAAAAATGTTTTTTCGTTACATCCGATTAATCGAACAGAAAAACTCATATCTTACACGATACCTGAAAAACGCGGGCTGAAAAAAGCCTTCGGGTATGATGAAGATACGTATCTGAATTTCACTGAATTAACCACAAAATACAATTACCCGAGTGAAGAGCACACAGTAACCACTGAAGACGGATACATACTCACGATATTTAGAATCTTAGCAAAGTGCAATGCACCTTCAAGACACTATCCAGTTCTTCTGATGCACGGTGTACTCGACAGCTCTGATGGATGGATAATTGCGGGCTCTGAAATAGGAATCGGCTTCGTTCTGGCACGTAACTGTTACGACGTATGGGCAGCCAATCACAGAGGAAACAGCTACTCTCGGAAACACGTGCGATTTGATGCAAACATAGACCCCGAGTATTGGGATTATACATTTGATGAACACGGAAACTATGATCTACCAGCCACTGTTGATTATGTTCTACAAAATACCGGGAAAGCGAAGATCAATTTCATTGGACACTCTCAAGGAACGACAAATTTTTACGTAATGAATTCTTTAAAACCACAATATAATGAAATGATAAACTTATCCATTCATCTTGCTCCTGTGGCTTGGTTAAAAAATACCGAAAGTATTATCTCAATAATTGCAGCACAAGGCAGTGGTCTAATTAAACAATTTCTCTCCGACATAGGAATAAGAGAATTCCTCGGAAAGAATCACATCATTCACGTTGCTTTTGAAGCATTATGTCAACTTGTACCGGATGAAATATGTGGTACAATGCTAGCCCTTACTGTTGGCTATGTGCAGGGGACTATAAACCCCAAACGCATTTCGGTTATATTTGGGCACGTACTAAACGGAGTTTCAATTAAAAACGCCGATCATTTCGGTCAACTTATAAGGTCTGGTAAGTTTCAACGTTACGATGAAGGAATAAGCGGTAATCTGAAAAGATACGGTAGGCAACATCCTGCCAACTACAATATGTCCTTAGTGACCGCACCAGTAGTGCTCGTCAGTGCCAAAAGAGATTGGTTGTCTTCCGTGAAAGATGTTAAAATTTTATGCTCAAAATTACCAAATTTGTTAGAAAATTATGAGATTCCTCTTGATTATTGGAGTCATCACAATCATTTATGGGACGATAACATAAAAGAGTATATTTTTCCCAAAATGTTTGAGTACTTAAATAAGTACAACTAA

Protein

MYHLLCVKIILTILFLKICHKNVFSLHPINRTEKLISYTIPEKRGLKKAFGYDEDTYLNFTELTTKYNYPSEEHTVTTEDGYILTIFRILAKCNAPSRHYPVLLMHGVLDSSDGWIIAGSEIGIGFVLARNCYDVWAANHRGNSYSRKHVRFDANIDPEYWDYTFDEHGNYDLPATVDYVLQNTGKAKINFIGHSQGTTNFYVMNSLKPQYNEMINLSIHLAPVAWLKNTESIISIIAAQGSGLIKQFLSDIGIREFLGKNHIIHVAFEALCQLVPDEICGTMLALTVGYVQGTINPKRISVIFGHVLNGVSIKNADHFGQLIRSGKFQRYDEGISGNLKRYGRQHPANYNMSLVTAPVVLVSAKRDWLSSVKDVKILCSKLPNLLENYEIPLDYWSHHNHLWDDNIKEYIFPKMFEYLNKYN

Similarity

Belongs to the AB hydrolase superfamily. Lipase family.

Feature

chain  Lipase

Uniprot

A0A2H1VHW7   A0A0L7KXY5   A0A2W1BMU4   A0A2A4K8I4   A0A212F4K7   A0A194PRT8   + More
A0A194QSZ0   A0A2J7QW32   A0A1V0M8B4   A0A291P144   A0A2W1BR25   A0A2W1BS78   A0A2H1W662   A0A0N0PB17   A0A088ML86   A0A194QDF4   A0A0N1PFF0   A0A0N0PBA5   A0A2W1BV86   A0A194R9R8   A0A0N1PHZ1   A0A194QC53   A0A194QBS0   A0A194QC12   A0A1W4UT02   A0A2H1VHX0   Q9VKT9   A0A0J9R159   B4HWR7   A0A1E1WS39   M9PCU5   A0A194QHS4   A0A1W4UT82   A0A0N1INH9   B4P0Q9   M9MRM3   B3MJK2   B4MWR9   A0A0J9TKN6   A0A194PS88   A0A3B0JHG8   Q29KR9   A0A0L0BXT4   A0A0N1IC21   A0A0M5J114   B3N5D9   A0A0R1DRH5   A0A0P8XGJ3   B4GSW4   A0A0Q9WQJ1   B4LUL0   B4Q9C6   V5I953   A0A0J9R0A7   A0A0N1I5B8   A0A3B0KDQ2   B4KKS2   A0A0R3NZX2   A0A194QRY3   A0A0Q5WBH0   Q9VKT8   A0A0N0PB30   I4DNB5   A0A0Q9WAE5   A0A194QHR9   B4HWR8   A0A2H1WEG8   A0A067RCF7   B4JE91   I4DJ25   A0A0L7LE27   E9I8R3   A0A0K8UT86   A0A2K8JM46   H9J3W1   E0V9B6   A0A2A4JCC5   B4JE90   A0A0C9PRI9   B3MJK3   A0A1W7R7P1   A0A0T6BEX7   A0A1A9UTK2   A0A2W1B637   A0A2H1WJP8   A0A067QLF8   B0W6G5   B0W003   A0A0L0C6A4   A0A194QQB7   A0A0N0PB52   A0A1B0A014   A0A1B0G0B6   A0A194Q1W6   A0A1B0B8Y7   A0A067R0F9   H9JXK1   A0A1I8N8T5   A0A1B0B8Z4   A0A194QC07  

Pubmed

26227816    28756777    22118469    26354079    28349297    28986331    + More
26385554    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    17994087    17550304    15632085    26108605    22651552    24845553    21282665    19121390    20566863    25315136   

EMBL

ODYU01002626    SOQ40371.1    JTDY01004649    KOB67911.1    KZ150017    PZC74945.1    + More
NWSH01000070    PCG79980.1    AGBW02010351    OWR48653.1    KQ459596    KPI95464.1    KQ461195    KPJ06656.1    NEVH01009768    PNF32784.1    KU755513    ARD71223.1    MF687644    ATJ44570.1    KZ149926    PZC77549.1    KZ149971    PZC76037.1    ODYU01006566    SOQ48517.1    KQ461072    KPJ09858.1    KJ579224    AIN34700.1    KQ459193    KPJ03000.1    KPJ09861.1    KPJ09856.1    PZC77544.1    KQ460473    KPJ14387.1    KPJ09857.1    KPJ03004.1    KPJ03003.1    KPJ03002.1    ODYU01002476    SOQ40012.1    AE014134    AY089586    AAF52971.1    AAL90324.1    CM002910    KMY89574.1    CH480818    EDW52462.1    GDQN01001224    JAT89830.1    AGB92891.1    KPJ03006.1    KPJ09860.1    CM000157    EDW87954.1    ADV37035.1    CH902620    EDV32370.2    CH963857    EDW76558.1    KMY89575.1    KQ459595    KPI95828.1    OUUW01000006    SPP81787.1    CH379061    EAL33105.2    JRES01001173    KNC24796.1    KPJ09854.1    CP012523    ALC38094.1    CH954177    EDV59018.1    KRJ97507.1    KPU73921.1    CH479189    EDW25473.1    KRF98484.1    CH940649    EDW64196.1    CM000361    EDX04568.1    GALX01003535    JAB64931.1    KMY89576.1    KPJ09859.1    SPP81788.1    CH933807    EDW12736.1    KRT04741.1    KQ461196    KPJ06301.1    KQS70596.1    BT022672    AAF52972.2    AAY55088.1    KPJ09855.1    AK402824    BAM19405.1    KRF81490.1    KPJ03001.1    EDW52463.1    ODYU01008119    SOQ51451.1    KK852794    KDR16428.1    CH916368    EDW03611.1    AK401293    BAM17915.1    JTDY01001496    KOB73727.1    GL761642    EFZ23043.1    GDHF01022533    JAI29781.1    KY031128    ATU82879.1    BABH01028866    DS234991    EEB09972.1    NWSH01002126    PCG69082.1    EDW03610.1    GBYB01003938    JAG73705.1    EDV32371.1    GEHC01000530    JAV47115.1    LJIG01001091    KRT85849.1    KZ150291    PZC71579.1    ODYU01009113    SOQ53300.1    KK853197    KDR09957.1    DS231848    EDS36639.1    DS231816    EDS37575.1    JRES01000842    KNC27786.1    KQ461190    KPJ07150.1    KQ461062    KPJ09925.1    CCAG010008921    KQ459590    KPI97395.1    JXJN01010106    KK852827    KDR15388.1    BABH01032765    JXJN01010151    JXJN01010152    JXJN01010153    JXJN01010154    KPJ02997.1   

Proteomes

UP000037510    UP000218220    UP000007151    UP000053268    UP000053240    UP000235965    + More
UP000192221    UP000000803    UP000001292    UP000002282    UP000007801    UP000007798    UP000268350    UP000001819    UP000037069    UP000092553    UP000008711    UP000008744    UP000008792    UP000000304    UP000009192    UP000027135    UP000001070    UP000005204    UP000009046    UP000078200    UP000002320    UP000092445    UP000092444    UP000092460    UP000095301   

PRIDE

Q9VKT9    M9PCU5    M9MRM3    Q9VKT8    H9J3W1    H9JXK1    + More

Pfam

PF04083   Abhydro_lipase        + More
PF00561   Abhydrolase_1
PF12146   Hydrolase_4

Interpro

IPR006693   AB_hydrolase_lipase        + More
IPR025483   Lipase_euk       
IPR029058   AB_hydrolase       
IPR000073   AB_hydrolase_1       
IPR022742   Hydrolase_4       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

A0A2H1VHW7   A0A0L7KXY5   A0A2W1BMU4   A0A2A4K8I4   A0A212F4K7   A0A194PRT8   + More
A0A194QSZ0   A0A2J7QW32   A0A1V0M8B4   A0A291P144   A0A2W1BR25   A0A2W1BS78   A0A2H1W662   A0A0N0PB17   A0A088ML86   A0A194QDF4   A0A0N1PFF0   A0A0N0PBA5   A0A2W1BV86   A0A194R9R8   A0A0N1PHZ1   A0A194QC53   A0A194QBS0   A0A194QC12   A0A1W4UT02   A0A2H1VHX0   Q9VKT9   A0A0J9R159   B4HWR7   A0A1E1WS39   M9PCU5   A0A194QHS4   A0A1W4UT82   A0A0N1INH9   B4P0Q9   M9MRM3   B3MJK2   B4MWR9   A0A0J9TKN6   A0A194PS88   A0A3B0JHG8   Q29KR9   A0A0L0BXT4   A0A0N1IC21   A0A0M5J114   B3N5D9   A0A0R1DRH5   A0A0P8XGJ3   B4GSW4   A0A0Q9WQJ1   B4LUL0   B4Q9C6   V5I953   A0A0J9R0A7   A0A0N1I5B8   A0A3B0KDQ2   B4KKS2   A0A0R3NZX2   A0A194QRY3   A0A0Q5WBH0   Q9VKT8   A0A0N0PB30   I4DNB5   A0A0Q9WAE5   A0A194QHR9   B4HWR8   A0A2H1WEG8   A0A067RCF7   B4JE91   I4DJ25   A0A0L7LE27   E9I8R3   A0A0K8UT86   A0A2K8JM46   H9J3W1   E0V9B6   A0A2A4JCC5   B4JE90   A0A0C9PRI9   B3MJK3   A0A1W7R7P1   A0A0T6BEX7   A0A1A9UTK2   A0A2W1B637   A0A2H1WJP8   A0A067QLF8   B0W6G5   B0W003   A0A0L0C6A4   A0A194QQB7   A0A0N0PB52   A0A1B0A014   A0A1B0G0B6   A0A194Q1W6   A0A1B0B8Y7   A0A067R0F9   H9JXK1   A0A1I8N8T5   A0A1B0B8Z4   A0A194QC07  

PDB

1HLG     E-value=4.54429e-51,     Score=509

KEGG

101739546    K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] | (RefSeq) lipase 1-like

PATHWAY

00100    Steroid biosynthesis - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0016788   GO:0016042   GO:0016740   GO:0016021   GO:0006629   GO:0000245   GO:0006397   GO:0005634   GO:0043565   GO:0050793   GO:0003676   GO:0016876   GO:0043039  

SignalP

Position:   1 - 25,         Likelihood:  0.857623

 

 

Length:

423

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.40837

Exp number, first 60 AAs:

0.35373

Total prob of N-in:

0.02200

outside

1  -  423

 

 

Pi

143.066821

Theta

147.607177

Tajima's D

-0.131155

CLR

0.536864

CSRT

0.332833358332083

Interpretation

Uncertain