Gene

KWMTBOMO08739

Pre Gene Modal

BGIBMGA007675

Annotation

PREDICTED:_aquaporin_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr15(+):3923898-3980214      View in EpiBrowser

Full name

Aquaporin AQPAe.a       + More
Aquaporin AQPAn.G      
Aquaporin AQPcic      
Aquaporin      

Alternative Name

BfWC1
Water channel 1

Location in the cell

PlasmaMembrane   Reliability : 4.837

CDS

ATGAAAACGGATTACGCTATGGATGAAATGCAGAAGAAGACAAGCTCCATCATCGGGCTGTCAGATGTAACGGACAACAAGCTGATCTGGAGGCAGCTGGTCGCGGAACTGGTTGGCACCTTCCTCCTTACTTCTATTGGCGTGGCCGCCTGCATCACCATCAACGCCAGCACAGCGCCCCACACCACCAGCATTGCGTTGTGCTTTGGCTTGCTCGTTGGATCTATTGTGCAGGGCATCGGTCACGTGTCTGGAGGACACATCAACCCCGCGGTGACAGCCGGTCTCTTCGCGGCGGGAGACATTAAGCTGCTAAAAGCAATCTTCTACATCGTAGTGCAGAGCCTCGGAGCAGTAGCTGGAGCCGCCTTTATCAGGTTGGCGATTCCTGCCGACAGCATCGGTGGTTTTGGTATGACCCTACCCGGACCCGGAGTTACAGAAGCGCAGGCCGTGCTGGTGGAGGCTCTGATCACGTTCGTGTTGGTCATGGTGGTGATGGGTGTGTGCGACCCGCAACGTAATGACCTCAAGGGTTCCGCTCCCCTGGCTATCGGACTCAGCATCACCGCCTGCCACGCTGCTGTCATACCTTTCACGGGATCCAGCATGAACCCGGCCCGAACATTCGGCCCAGCCTTGGTGATCGGCAACTGGACATCTCAATGGGTTTACTGGGTGGGTCCCGTCGTGGGCGGCGTGATCGCTGGACTACTCTACAAATTCGTTCTGCGCATCAAAAAAGCCGGAGACACCGGCTCTTATGACTTCTAA

Protein

MKTDYAMDEMQKKTSSIIGLSDVTDNKLIWRQLVAELVGTFLLTSIGVAACITINASTAPHTTSIALCFGLLVGSIVQGIGHVSGGHINPAVTAGLFAAGDIKLLKAIFYIVVQSLGAVAGAAFIRLAIPADSIGGFGMTLPGPGVTEAQAVLVEALITFVLVMVVMGVCDPQRNDLKGSAPLAIGLSITACHAAVIPFTGSSMNPARTFGPALVIGNWTSQWVYWVGPVVGGVIAGLLYKFVLRIKKAGDTGSYDF

Description

Forms a water-specific channel.

Subunit

Homotetramer.

Similarity

Belongs to the MIP/aquaporin (TC 1.A.8) family.

Keywords

Complete proteome   Membrane   Reference proteome   Repeat   Transmembrane   Transmembrane helix   Transport   Direct protein sequencing  

Feature

chain  Aquaporin AQPAe.a

Uniprot

Q5W916   H9BF90   A0A345VNI4   A0A212FCF2   A0A140HDB9   A0A3S2PJH7   + More
A0A220K8M2   T1SST5   I4DIW8   I4DM67   A0A3Q9EMU2   T1SR25   C0STV3   A0A1P8SSF7   A0A2W1BNT8   A0A0L7LDL7   A0A1L4AIE1   A0A194QMA5   A0A1Q3G5F9   A0A2H1VYP1   Q9NHW7   A0A1Q3G5I2   T1E2A4   U5ENE4   A0A023EL67   A0A1Q3G4G7   V5I8V0   A0A2M4CT83   A0A2M3ZFM7   A0A2M3ZZS9   A0A2M3ZZX3   A0A1Q3G4L3   A0A023ELI2   A0A182NZ08   A0A1Y0AWS9   A0A1L8DE52   A0A1Y9J090   A0A168SEB1   A0A1Y9GLM3   A0A1L8DEI5   Q7PWV1   A0A2M4CUY2   A0A2M3ZZY9   A8CWH6   A0A182Y976   A0A1L8DE34   A0A139WB77   E0VGZ9   A0A2M4CV65   A0A0K8TPJ5   M1VMW0   A0A0R1DR91   A0A1I8MU03   A0A1Q3G5G8   B5UA25   I7HAA5   Q23808   B4P643   A0A1L8EI33   Q25074   A0A1L8ECU6   A0A1J1ILA5   B3NSF8   A0A0A1X473   A0A0R1DQF3   A0A0M4E526   A0A1I8Q620   B4KR23   A0A0B4KET4   H6V591   Q9V5Z7   F3YDC9   T1P7R4   A0A0A1WSB4   A0A060DEU1   A0A3B0JN36   A0A0B6VQ53   B4MQJ3   B5UA26   A0A0B4KFN8   J3JYA8   B3MFB9   A0A1Q3G4J0   A0A1Q3G4P7   B5E021   A0A0R3NLV2   B4HNI0   A0A0P8XM48   B4J8Z7   A0A1W4UGP5   A0A0R3NU72   A0A1Y1M9T7   A0A1W4U5Q7   W8C9U4   A0A0L0BUX4   A0A0L0CIZ6   B4LQ46   W8BN31   A0A0B4KFD6   V9IMC7  

Pubmed

22285686    30012538    22118469    28630352    22651552    26354079    + More
28756777    26227816    27914170    10971718    17510324    24330624    24945155    28341416    12364791    18194529    25244985    18362917    19820115    20566863    26369729    23531819    17994087    17550304    25315136    22767214    8944756    7542238    10469254    25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22516182    15632085    28004739    24495485    26108605   

EMBL

AB178640    BAD69569.1    JQ011314    JQ011315    AFC34081.1    AFC34082.1    + More
MH230174    AXJ14286.1    AGBW02009197    OWR51412.1    KT819587    AMO02270.1    RSAL01000014    RVE53247.1    MF319725    ASJ26439.1    KC999954    AGT50943.1    AK401236    KQ459596    BAM17858.1    KPI95459.1    AK402385    BAM19007.1    MH333284    AZQ26943.1    KC999953    AGT50942.1    AB469882    BAH47554.1    KX943612    APY26693.1    KZ150017    PZC74947.1    JTDY01001638    KOB73271.1    KX808645    API68429.1    KQ461195    KPJ06652.1    GFDL01000003    JAV35042.1    ODYU01004959    SOQ45354.1    AF218314    CH477274    GFDL01000002    JAV35043.1    GALA01000914    JAA93938.1    GANO01000630    JAB59241.1    GAPW01003656    JAC09942.1    GFDL01000343    JAV34702.1    GALX01004050    JAB64416.1    GGFL01004355    MBW68533.1    GGFM01006626    MBW27377.1    GGFK01000755    MBW34076.1    GGFK01000776    MBW34097.1    GFDL01000336    JAV34709.1    GAPW01003507    JAC10091.1    KY921810    ART29399.1    GFDF01009341    JAV04743.1    KU055613    ANC68081.1    APCN01003350    GFDF01009340    JAV04744.1    AAAB01008984    GGFL01004969    MBW69147.1    GGFK01000792    MBW34113.1    EU124628    ABV60346.1    GFDF01009355    JAV04729.1    KQ971374    KYB25143.1    DS235154    EEB12655.1    GGFL01005059    MBW69237.1    GDAI01001324    JAI16279.1    AB741517    BAM83568.1    CM000158    KRJ99518.1    GFDL01000001    JAV35044.1    AB433197    BAG72254.1    AB713909    BAM26200.1    X97159    X77957    EDW90918.1    GFDG01000530    JAV18269.1    U51638    GFDG01002396    JAV16403.1    CVRI01000055    CRL01023.1    CH954179    EDV56460.1    GBXI01008163    JAD06129.1    KRJ99519.1    CP012524    ALC41291.1    CH933808    EDW10379.1    AE013599    AGB93424.1    JN791442    JN791443    AFA35130.1    BT023883    U38807    BT126290    AEB39651.1    AGB93423.1    KA644562    AFP59191.1    GBXI01012751    GBXI01002562    JAD01541.1    JAD11730.1    KJ599672    AIB09141.1    OUUW01000001    SPP74716.1    AB985768    BAQ25599.1    CH963849    EDW74382.1    AB433198    BAG72255.1    AGB93425.1    BT128232    AEE63193.1    CH902619    EDV35593.1    GFDL01000332    JAV34713.1    GFDL01000309    JAV34736.1    CM000071    EDY68905.1    KRT01863.1    CH480816    EDW47416.1    KPU75735.1    CH916367    EDW01346.1    KRT01862.1    GEZM01036579    GEZM01036578    JAV82582.1    GAMC01006346    JAC00210.1    JRES01001300    KNC23793.1    JRES01000418    KNC31439.1    CH940648    EDW61331.2    GAMC01006348    JAC00208.1    AGB93426.1    JR052623    AEY61741.1   

Proteomes

UP000007151    UP000283053    UP000053268    UP000037510    UP000053240    UP000008820    + More
UP000075884    UP000076407    UP000075840    UP000007062    UP000076408    UP000007266    UP000009046    UP000002282    UP000095301    UP000183832    UP000008711    UP000092553    UP000095300    UP000009192    UP000000803    UP000268350    UP000007798    UP000007801    UP000001819    UP000001292    UP000001070    UP000192221    UP000037069    UP000008792   

PRIDE

Q5W916    Q23808    Q9V5Z7    F3YDC9   

Pfam

PF00230   MIP

Interpro

IPR023271   Aquaporin-like        + More
IPR034294   Aquaporin_transptr       
IPR000425   MIP       
IPR022357   MIP_CS       

SUPFAM

SSF81338   SSF81338       

Gene 3D

1.20.1080.10    

CDD

cd00333  MIP

ProteinModelPortal

Q5W916   H9BF90   A0A345VNI4   A0A212FCF2   A0A140HDB9   A0A3S2PJH7   + More
A0A220K8M2   T1SST5   I4DIW8   I4DM67   A0A3Q9EMU2   T1SR25   C0STV3   A0A1P8SSF7   A0A2W1BNT8   A0A0L7LDL7   A0A1L4AIE1   A0A194QMA5   A0A1Q3G5F9   A0A2H1VYP1   Q9NHW7   A0A1Q3G5I2   T1E2A4   U5ENE4   A0A023EL67   A0A1Q3G4G7   V5I8V0   A0A2M4CT83   A0A2M3ZFM7   A0A2M3ZZS9   A0A2M3ZZX3   A0A1Q3G4L3   A0A023ELI2   A0A182NZ08   A0A1Y0AWS9   A0A1L8DE52   A0A1Y9J090   A0A168SEB1   A0A1Y9GLM3   A0A1L8DEI5   Q7PWV1   A0A2M4CUY2   A0A2M3ZZY9   A8CWH6   A0A182Y976   A0A1L8DE34   A0A139WB77   E0VGZ9   A0A2M4CV65   A0A0K8TPJ5   M1VMW0   A0A0R1DR91   A0A1I8MU03   A0A1Q3G5G8   B5UA25   I7HAA5   Q23808   B4P643   A0A1L8EI33   Q25074   A0A1L8ECU6   A0A1J1ILA5   B3NSF8   A0A0A1X473   A0A0R1DQF3   A0A0M4E526   A0A1I8Q620   B4KR23   A0A0B4KET4   H6V591   Q9V5Z7   F3YDC9   T1P7R4   A0A0A1WSB4   A0A060DEU1   A0A3B0JN36   A0A0B6VQ53   B4MQJ3   B5UA26   A0A0B4KFN8   J3JYA8   B3MFB9   A0A1Q3G4J0   A0A1Q3G4P7   B5E021   A0A0R3NLV2   B4HNI0   A0A0P8XM48   B4J8Z7   A0A1W4UGP5   A0A0R3NU72   A0A1Y1M9T7   A0A1W4U5Q7   W8C9U4   A0A0L0BUX4   A0A0L0CIZ6   B4LQ46   W8BN31   A0A0B4KFD6   V9IMC7  

PDB

2ZZ9     E-value=4.71541e-45,     Score=454

KEGG

692464    K09884 aquaporin rerated protein, invertebrate | (RefSeq) aqp; aquaporin

GO

GO:0016021   GO:0015267   GO:0005886   GO:0015250   GO:0006833   GO:0030104   GO:0055085   GO:0046662   GO:0003014   GO:0005215   GO:0006810   GO:0016020   GO:0003700   GO:0005634   GO:0043565   GO:0050793   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR19139  

Subcellular location

Membrane  

Length:

257

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

131.77754

Exp number, first 60 AAs:

22.30773

Total prob of N-in:

0.96295

POSSIBLE N-term signal

sequence

inside

1  -  36

TMhelix

37  -  59

outside

60  -  63

TMhelix

64  -  86

inside

87  -  106

TMhelix

107  -  129

outside

130  -  148

TMhelix

149  -  168

inside

169  -  179

TMhelix

180  -  202

outside

203  -  221

TMhelix

222  -  244

inside

245  -  257

 

 

Pi

199.733142

Theta

173.911694

Tajima's D

0.55242

CLR

0.450126

CSRT

0.533323333833308

Interpretation

Uncertain