Gene

KWMTBOMO08729  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007912

Annotation

PREDICTED:_retinol_dehydrogenase_12-like_[Papilio_machaon]

Location

Bomo_Chr15(-):3636504-3641944      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 1.977

CDS

ATGGTGTCGGCTCCGGTGATTTATGCAGCAGTGCCCATCTCAGTAGTAGTGGCGATTGGATTAATACGTAAACTGAGATCCAGAAATTGGGGCAAATGTACTAGTAATACATGTCTGAGAGGCAAAACCTTTCTGATAACCGGTGCAAACAGTGGTATCGGACTTGAAACAGCTAAAGCCTTGGTTAAAAGAAAAGCCCGCGTTATCTTTGCATGCAGAGACATTGCAAAGGCGAAAGAAGTTATTGCCGCAATACGAGAGGAACAGCCAAATGGTGGTGAAATGATTCCGATGCAGCTTGACCTTTCATCATTTGAATCTATAGAAAATTTTGTGGATATTATAAAGGCTGGTTTCCATAAAATAGATGTCCTTATAAACAATGCTGGTGTTGTTGTTCCTTTGAATCAAGATGAGAAGACAAAAGAAGGATTTGAAATACATTTTGGTGTGAACCACCTAGGCCACTTTTATCTTACTAATCTTTTGTTAGACCATTTGAAGAGGGCTACTCCAAGTAGAATTGTAATCGTGTCTTCAACGTTACACGAAAAAGGAAAAATCGATTTTGACGACCTAAACTTAAGGTCGGAAATAGAATTAGCGAAAAAGGGCAAAAGCGGTCGTCACAACCCCGGTTATTGCAACTCCAAACTAATGAATGCATACTTTATGAGATCATTAGCTGCAAAATTGAGAAATTCTGGGGTCGATGTCAACGCATGCTGCCCAGGATTCTGTTACACGAACTTATTCAGATATTCGGTAAAATGGTACCACTACATTATGATGGCGCCAATCTTTCTTCTTTTCATGAGATCGGCTAAACAGGGTTCCGAAACAGTATTGTTCTGTGCCACAGATCACAGTCTTGAAGGGAAATCGGGTCGGTTTTACCGCGACTGTGTCGAATACGACACCAAGTATCCATTTGACAGGGCCGTCGAGAACAAACTGTGGGAGGTCAGCGAGGACCTCATCAAAGCCAGGAAGCCGCTGTGA

Protein

MVSAPVIYAAVPISVVVAIGLIRKLRSRNWGKCTSNTCLRGKTFLITGANSGIGLETAKALVKRKARVIFACRDIAKAKEVIAAIREEQPNGGEMIPMQLDLSSFESIENFVDIIKAGFHKIDVLINNAGVVVPLNQDEKTKEGFEIHFGVNHLGHFYLTNLLLDHLKRATPSRIVIVSSTLHEKGKIDFDDLNLRSEIELAKKGKSGRHNPGYCNSKLMNAYFMRSLAAKLRNSGVDVNACCPGFCYTNLFRYSVKWYHYIMMAPIFLLFMRSAKQGSETVLFCATDHSLEGKSGRFYRDCVEYDTKYPFDRAVENKLWEVSEDLIKARKPL

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Belongs to the peptidase C2 family.

Uniprot

H9JEG5   A0A2A4J2B2   A0A194QNT9   A0A2W1BJ13   A0A3S2NPV7   A0A1Q3G5I0   + More
A0A212F629   A0A194PWE0   A0A212ERM8   A0A0L7LFN1   S4P0J8   E0VDD8   A0A1B6BX84   A0A0C9QV02   A0A0P4VR99   R4FKX0   A0A2J7Q0L8   A0A067RU66   A0A1B6L1W5   A0A023F7T6   A0A0V0GBR5   A0A224XFS1   A0A0A9YDT0   A0A2R7WJW3   A0A0K8SB02   E2ADL5   A0A026WRM2   A0A158NZW1   A0A151J2K3   A0A195F371   A0A195CNR6   A0A195BLF2   A0A1B6K4T9   E9IT46   A0A151WZX3   F4WIE2   E2C9X5   D6WFR6   A0A087ZX60   A0A232F566   A0A2A3EBL7   A0A0M8ZRS6   A0A3L8DYV4   A0A1W4XJ42   A0A0L7R926   A0A154NYW2   A0A182ML63   A0A2P8YTG4   A0A1B6GF00   A0A1Y1MH66   A0A182Y7X1   A0A1B6FJF3   A0A182SFS5   A0A1B6GC91   A0A084WML5   N6U4K1   Q16QL8   A0NEU8   A0A182UYQ2   A0A182NIW1   W5J866   A0A0T6B2S4   A0A182UJP6   A0A2J7Q0K2   A0A1S4EIL9   A0A3Q0J5E5   A0A1S4EIP8   A0A182PRZ3   A0A1L8E4V6   A0A1S3DB53   A0A182RU56   A0A182I4B7   A0A182X4C2   A0A0P5FHU3   A0A0P5UAJ0   A0A0P6A8F6   A0A1B6GPR4   A0A0P4X3Q9   A0A0P5INM4   A0A0P4WM74   A0A165AAF7   A0A0P5PAF5   A0A0P5CRM4   A0A336KK53   A0A336M7R4   A0A3R7QPT9   A0A0P5E503   A0A1J1IXS7   A0A0P6DX19   A0A1L8E560   A0A1B0D040   A0A0P5K7Q1   A0A0P5T1P7   A0A182FFE2   A0A1S4J8U1   A0A1Q3FLN9   B0W853  

Pubmed

19121390    26354079    28756777    22118469    26227816    23622113    + More
20566863    27129103    24845553    25474469    25401762    20798317    24508170    21347285    21282665    21719571    18362917    19820115    28648823    30249741    29403074    28004739    25244985    24438588    23537049    17510324    12364791    14747013    17210077    20920257    23761445   

EMBL

BABH01003057    NWSH01003932    PCG65664.1    KQ461195    KPJ06640.1    KZ150012    + More
PZC75062.1    RSAL01000014    RVE53240.1    GEYN01000191    JAV44798.1    AGBW02010081    OWR49192.1    KQ459596    KPI95450.1    AGBW02013012    OWR44101.1    JTDY01001300    KOB74267.1    GAIX01007669    JAA84891.1    DS235073    EEB11394.1    GEDC01031733    JAS05565.1    GBYB01007584    JAG77351.1    GDKW01001665    JAI54930.1    ACPB03001482    GAHY01001663    JAA75847.1    NEVH01019965    PNF22121.1    KK852415    KDR24355.1    GEBQ01022264    JAT17713.1    GBBI01001410    JAC17302.1    GECL01001330    JAP04794.1    GFTR01005100    JAW11326.1    GBHO01013808    JAG29796.1    KK854957    PTY19937.1    GBRD01015359    JAG50467.1    GL438820    EFN68377.1    KK107139    EZA57749.1    ADTU01005049    KQ980404    KYN16218.1    KQ981856    KYN34627.1    KQ977580    KYN01744.1    KQ976440    KYM86515.1    GECU01001251    JAT06456.1    GL765434    EFZ16373.1    KQ982629    KYQ53426.1    GL888175    EGI66073.1    GL453904    EFN75273.1    KQ971319    EEZ99585.1    NNAY01000983    OXU25620.1    KZ288292    PBC29080.1    KQ435883    KOX69795.1    QOIP01000003    RLU25129.1    KQ414628    KOC67370.1    KQ434775    KZC04060.1    AXCM01000273    PYGN01000369    PSN47539.1    GECZ01008760    JAS61009.1    GEZM01031355    JAV84931.1    GECZ01028757    GECZ01019464    GECZ01003948    JAS41012.1    JAS50305.1    JAS65821.1    GECZ01016086    GECZ01009711    JAS53683.1    JAS60058.1    ATLV01024482    KE525352    KFB51459.1    APGK01049519    KB741156    KB632169    ENN73512.1    ERL89431.1    CH477744    EAT36698.1    AAAB01008960    EAU76619.2    ADMH02001882    ETN60662.1    LJIG01016080    KRT81676.1    PNF22118.1    GFDF01000420    JAV13664.1    APCN01002300    GDIQ01255060    JAJ96664.1    GDIP01153150    GDIQ01153386    GDIP01115754    GDIP01115753    GDIP01041163    GDIQ01036817    JAK98339.1    JAL87961.1    GDIP01214393    GDIP01214392    GDIP01140051    GDIP01045869    GDIQ01075665    JAM57846.1    JAN19072.1    GECZ01005345    JAS64424.1    GDIP01254926    JAI68475.1    GDIQ01211265    JAK40460.1    GDIP01254927    JAI68474.1    LRGB01000642    KZS17371.1    GDIQ01131356    JAL20370.1    GDIP01167631    JAJ55771.1    UFQS01000608    UFQT01000608    SSX05314.1    SSX25675.1    UFQS01000513    UFQT01000513    SSX04509.1    SSX24873.1    QCYY01000029    ROT86048.1    GDIP01164997    JAJ58405.1    CVRI01000064    CRL05075.1    GDIQ01071018    JAN23719.1    GFDF01000389    JAV13695.1    AJVK01009809    GDIQ01188220    JAK63505.1    GDIP01132300    JAL71414.1    GFDL01006632    JAV28413.1    DS231857    EDS38678.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000283053    UP000007151    UP000053268    + More
UP000037510    UP000009046    UP000015103    UP000235965    UP000027135    UP000000311    UP000053097    UP000005205    UP000078492    UP000078541    UP000078542    UP000078540    UP000075809    UP000007755    UP000008237    UP000007266    UP000005203    UP000215335    UP000242457    UP000053105    UP000279307    UP000192223    UP000053825    UP000076502    UP000075883    UP000245037    UP000076408    UP000075901    UP000030765    UP000019118    UP000030742    UP000008820    UP000007062    UP000075903    UP000075884    UP000000673    UP000075902    UP000079169    UP000075885    UP000075900    UP000075840    UP000076407    UP000076858    UP000283509    UP000183832    UP000092462    UP000069272    UP000002320   

PRIDE

H9JEG5   

Pfam

PF00106   adh_short        + More
PF13833   EF-hand_8
PF13405   EF-hand_6
PF01067   Calpain_III
PF00648   Peptidase_C2
PF09446   VMA21
PF04628   Sedlin_N
PF01916   DS

Interpro

IPR002347   SDR_fam        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR022682   Calpain_domain_III       
IPR000169   Pept_cys_AS       
IPR018247   EF_Hand_1_Ca_BS       
IPR036213   Calpain_III_sf       
IPR033883   C2_III       
IPR038765   Papain-like_cys_pep_sf       
IPR022684   Calpain_cysteine_protease       
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       
IPR022683   Calpain_III       
IPR001300   Peptidase_C2_calpain_cat       
IPR019013   Vma21       
IPR036982   Deoxyhypusine_synthase_sf       
IPR002773   Deoxyhypusine_synthase       
IPR029035   DHS-like_NAD/FAD-binding_dom       
IPR006722   Sedlin       
IPR011012   Longin-like_dom_sf       

SUPFAM

SSF51735   SSF51735        + More
SSF49758   SSF49758       
SSF47473   SSF47473       
SSF54001   SSF54001       
SSF64356   SSF64356       
SSF52467   SSF52467       

Gene 3D

3.40.910.10    

CDD

cd00044  CysPc
cd00214  Calpain_III

ProteinModelPortal

H9JEG5   A0A2A4J2B2   A0A194QNT9   A0A2W1BJ13   A0A3S2NPV7   A0A1Q3G5I0   + More
A0A212F629   A0A194PWE0   A0A212ERM8   A0A0L7LFN1   S4P0J8   E0VDD8   A0A1B6BX84   A0A0C9QV02   A0A0P4VR99   R4FKX0   A0A2J7Q0L8   A0A067RU66   A0A1B6L1W5   A0A023F7T6   A0A0V0GBR5   A0A224XFS1   A0A0A9YDT0   A0A2R7WJW3   A0A0K8SB02   E2ADL5   A0A026WRM2   A0A158NZW1   A0A151J2K3   A0A195F371   A0A195CNR6   A0A195BLF2   A0A1B6K4T9   E9IT46   A0A151WZX3   F4WIE2   E2C9X5   D6WFR6   A0A087ZX60   A0A232F566   A0A2A3EBL7   A0A0M8ZRS6   A0A3L8DYV4   A0A1W4XJ42   A0A0L7R926   A0A154NYW2   A0A182ML63   A0A2P8YTG4   A0A1B6GF00   A0A1Y1MH66   A0A182Y7X1   A0A1B6FJF3   A0A182SFS5   A0A1B6GC91   A0A084WML5   N6U4K1   Q16QL8   A0NEU8   A0A182UYQ2   A0A182NIW1   W5J866   A0A0T6B2S4   A0A182UJP6   A0A2J7Q0K2   A0A1S4EIL9   A0A3Q0J5E5   A0A1S4EIP8   A0A182PRZ3   A0A1L8E4V6   A0A1S3DB53   A0A182RU56   A0A182I4B7   A0A182X4C2   A0A0P5FHU3   A0A0P5UAJ0   A0A0P6A8F6   A0A1B6GPR4   A0A0P4X3Q9   A0A0P5INM4   A0A0P4WM74   A0A165AAF7   A0A0P5PAF5   A0A0P5CRM4   A0A336KK53   A0A336M7R4   A0A3R7QPT9   A0A0P5E503   A0A1J1IXS7   A0A0P6DX19   A0A1L8E560   A0A1B0D040   A0A0P5K7Q1   A0A0P5T1P7   A0A182FFE2   A0A1S4J8U1   A0A1Q3FLN9   B0W853  

PDB

3RD5     E-value=1.54474e-31,     Score=339

KEGG

101741725    no KO assigned | (RefSeq) retinol dehydrogenase 11-like

GO

GO:0016021   GO:0016630   GO:0008234   GO:0070072   GO:0006888   GO:0008612   GO:0005737  

PANTHER

PTHR11703  

Length:

333

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

32.17362

Exp number, first 60 AAs:

19.02017

Total prob of N-in:

0.07936

POSSIBLE N-term signal

sequence

outside

1  -  4

TMhelix

5  -  22

inside

23  -  333

 

 

Pi

40.821656

Theta

35.833527

Tajima's D

-1.702733

CLR

2.39602

CSRT

0.0362981850907455

Interpretation

Uncertain