Gene

KWMTBOMO08724  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007670

Annotation

alpha-esterase_25_[Bombyx_mori]

Location

Bomo_Chr15(+):3539215-3541648      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

PlasmaMembrane   Reliability : 3.026

CDS

ATGACGATATCGTCGAAAAAGAAATTAAAATATGTAGCTATATTTGCTATTATAGCGGGTGCAATAGCAGGACCGGTAATTTATTATGTGGTAACATTCGAGAGCTTTCCCCAAGTAAAAACAAAATTAGGAACAATTGTCGGCTTATACGCGAGCGACGGTAACTACAATATGTACATGGGTGTCCCTTACGCTGTGGTTAATAAATCTAATCCGTTTGGGGACTCTCAACCCTACCCGAAATTTATAGATTCGCTGAAAGCAGATAATGACTCTAGAATGTGCCCGCAAGTAGATCAATATAATAATACGCTAATTGGTACTTTAGATTGTTTGAATTTGAACATTTATGTCCCAATTTCGGACAAGATCAGTAAAGAAATCAAACTGCCAGTATTAGTGTTTATACATGACAGTTGGTACGATTTCGGATCTAGCGGAAGATATGTTTATGGTCCGAAATATTTGATGAAGCATGAAATTATTTTGGTGACGATTAATTTCCGCCTAGGGCCTTATGGGTTCTTGTGTGTAGACACACCAGAAGTATCCGGTAACCAAGGGCTTAAAGATCAAATTCTAGCTTTACGTTGGGTTAAAGAAAATATCGATGCTTTTGGTGGAGACCCTGGAAAAGTTACGCTGGCTGGCATCGGCACAGGAGGCGAAAATGTCCTCATGCATGTACTTTATGGCAACAAAGATTTATTCAGTAAGGTCATAATAGACAGTGGATTGACACTTCCAACATTGGTGATGGCTGAAACAGATTCGACAATACCATTCCGATTGGCCCAAGATCTTGGTTTTATTGCGTACCACGTAAAAGAAGCAATTAATTTTTTAGCTACTCAAGATAGTCGTAGAGTTATACGATCATCATATAAATATGACTTTAGATATAAGCCCTGCATTGAAAACAATGCCACTGGAGTGAACACATTCGCTACAAAACATATGTCGCAAATAAACAGAATTCGAGATATAAACAAAATAAAGTTTATGATTGGCCAAACTAATAATGAAAGACTATACAAATACTCAGATACTGTCTTCGATAGTTCTGAATATCGTAATATATTCGAGGATGAGTTATACGATTTGTTTAATTTTGAGGCTGACAAGTTGATGAGAATGGAAAAGTACGTGCGACATTTTTACATCGGTAACGAAGATATTACGGATGAAGTCAAACCAAATCTAATTCATTTCTTTAATGACTTGTATCACAATCATCCAACGAAAAGGACGATTAATAAATTTATTGAAAGCGGAGCGAACATTATTTATTACAGCATATTTTCTTACGTAGGAGGAAGAAATTACATGAGGAACTTTTACAGCATCAACGACACATACCCAAACGCAACGAGAGCTGACCAAATCGGGTATTTATTTGACGTGTCTTACATGAATAGCAACGTGACCGAAAATGATCGACTTGTAATTGATCGTATGACCACTCTGTGGGCAAATTTTGTGAAATATGGCAATCCAACTCCTGATATATCAGATATTCTACCAGTGAAATGGGAAACAGTTACTAACAAGTCCCTAGCGTATTACGACATCAACAAAAATGTTACGAGCGAAGTAAGACCGTACCACGACAGAATGGCGTTTTGGGATCTCTTCTACAAATCCAATGGAATATTACAGAGATCTATTAGGGCGAAATAA

Protein

MTISSKKKLKYVAIFAIIAGAIAGPVIYYVVTFESFPQVKTKLGTIVGLYASDGNYNMYMGVPYAVVNKSNPFGDSQPYPKFIDSLKADNDSRMCPQVDQYNNTLIGTLDCLNLNIYVPISDKISKEIKLPVLVFIHDSWYDFGSSGRYVYGPKYLMKHEIILVTINFRLGPYGFLCVDTPEVSGNQGLKDQILALRWVKENIDAFGGDPGKVTLAGIGTGGENVLMHVLYGNKDLFSKVIIDSGLTLPTLVMAETDSTIPFRLAQDLGFIAYHVKEAINFLATQDSRRVIRSSYKYDFRYKPCIENNATGVNTFATKHMSQINRIRDINKIKFMIGQTNNERLYKYSDTVFDSSEYRNIFEDELYDLFNFEADKLMRMEKYVRHFYIGNEDITDEVKPNLIHFFNDLYHNHPTKRTINKFIESGANIIYYSIFSYVGGRNYMRNFYSINDTYPNATRADQIGYLFDVSYMNSNVTENDRLVIDRMTTLWANFVKYGNPTPDISDILPVKWETVTNKSLAYYDINKNVTSEVRPYHDRMAFWDLFYKSNGILQRSIRAK

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

H9JDS3   B1Q139   B8YPE7   A0A0L7L3V0   A0A2A4K075   A0A1U9X1V1   + More
A0A2A4JZ33   A0A1U9X1V6   A0A194PEF7   A0A2W1BQY3   A0A194Q254   D5G3E0   H9IUA7   A0A0N1PJ90   A0A194Q887   A0A0N1IPF0   M1RGF2   H9J1Y0   B1Q141   A0A2I6RJM2   A0A194PDI7   B3GEF6   A0A2H1VAI9   A0A1U9X1V3   A0A2H1VAJ0   A0A0L7L0K6   A0A212FJ60   A0A0B4RXS5   A0A194RIH0   A0A0N1IGW1   A0A437AWV6   A0A3S2LSF5   A0A194Q249   A0A194PJ15   B1Q137   A0A2A4JR93   A0A194Q2Q8   A0A2H1WRP2   A0A212FJ67   A0A1U9X1V0   A0A1U9X1Z0   A0A3G1T174   A0A2A4JU91   A0A2W1BZX4   A0A2H1VEA4   A0A2H1VCN6   A0A2H1VCP0   A0A2H1VCN0   A0A2A4K7E9   A0A1U9X1U7   H9IWJ7   A0A0L7LED6   D5G3E3   A0A2W1BTR6   A0A2H1VCT7   A0A2H1VCQ9   H9IZW1   H9JF44   D5G3E2   D5G3E1   A0A3S2NSH9   A0A2H1VCR3   H9J066   H9J067   A0A0L7KY57   A0A2H1VCT9   A0A0L7L1R0   A0A0C5BXH5   A0A2H1WHB4   H9JDS4   A0A2A4JYV0   A0A1U9X1X9   A0A194QYN7   A0A2H1VCP9   D5G3E4   A0A2A4JSH8   A0A2W1BXP7   A0A2W1BVP4   A0A2W1BNW5   A0A2W1BTK5   A0A0F7QHL9   A0A194PD51   A0A1U9X1Z4   A4UA26   A0A212FJ53   A0A2A4JU71   A0A2A4JU07   A0A2W1BJM9   A0A2A4JHL2   H9IUE5   A0A0K0XRM2   A0A0C5C1P7   A0A2H1VH39   A0A212EY53   D3GDM3   A0A0L7KQ39   A0A0B4RY83   H9IWJ8   A0A1U9X1U4   A0A0L7LKE5  

EC Number

3.1.1.-

Pubmed

19121390    26227816    26354079    28756777    20005949    22118469    + More
25803580    17257210    26198868   

EMBL

BABH01003066    EU523534    ACB12413.2    FJ556877    ACL83460.1    JTDY01003106    + More
KOB70142.1    NWSH01000356    PCG77070.1    KY021842    AQY62731.1    PCG77069.1    KY021858    AQY62747.1    KQ459606    KPI91074.1    KZ150007    PZC75160.1    KQ459564    KPI99621.1    FJ997304    ADF43469.1    BABH01001500    KQ459837    KPJ19757.1    KPI99620.1    KQ460400    KPJ14974.1    KC200270    AGG20205.1    BABH01007753    EU523536    ACB12415.1    KY304479    AUN86410.1    KPI91073.1    EU688968    ACD80422.1    ODYU01001525    SOQ37858.1    KY021841    AQY62730.1    SOQ37859.1    JTDY01003780    KOB69017.1    AGBW02008309    OWR53771.1    KJ023212    AIY69040.1    KQ460205    KPJ17125.1    KPJ19760.1    RSAL01000314    RVE42639.1    RSAL01000258    RVE43396.1    KPI99616.1    KPI91075.1    EU523532    ACB12411.1    NWSH01000834    PCG73942.1    KPI99618.1    ODYU01010533    SOQ55708.1    OWR53772.1    KY021850    AQY62739.1    KY021887    AQY62776.1    MG846884    AXY94736.1    NWSH01000660    PCG74962.1    KZ149903    PZC78410.1    ODYU01001845    SOQ38604.1    SOQ38609.1    SOQ38610.1    SOQ38608.1    NWSH01000067    PCG79999.1    KY021848    AQY62737.1    BABH01021273    JTDY01001549    KOB73566.1    FJ997307    ADF43472.1    PZC78409.1    SOQ38611.1    SOQ38612.1    SOQ38607.1    BABH01019018    BABH01026894    FJ997306    ADF43471.1    FJ997305    ADF43470.1    RVE43394.1    SOQ38605.1    BABH01018991    BABH01018992    BABH01018995    JTDY01004572    KOB67996.1    SOQ38606.1    JTDY01003509    KOB69443.1    KP001158    AJN91203.2    ODYU01008680    SOQ52463.1    NWSH01000400    PCG76673.1    KY021873    AQY62762.1    KQ460947    KPJ10567.1    SOQ38613.1    FJ997308    ADF43473.1    PCG74961.1    PZC78414.1    PZC78411.1    KZ149946    PZC76749.1    PZC78412.1    LC017770    BAR64784.1    KPI91162.1    KY021884    AQY62773.1    DQ680829    ABH01082.1    OWR53773.1    PCG74959.1    PCG74960.1    PCG74963.1    KZ150132    PZC73036.1    NWSH01001418    PCG71299.1    BABH01001182    KC200271    AGG20206.1    KP938883    AKS40364.1    KP001149    AJN91194.1    ODYU01002500    SOQ40071.1    AGBW02011630    OWR46387.1    FJ652455    ACV60239.1    JTDY01007420    KOB65210.1    KJ023211    AIY69039.1    KY021838    AQY62727.1    JTDY01000777    KOB75922.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053268    UP000053240    UP000007151    + More
UP000283053   

PRIDE

H9JDS3    B1Q139    H9IUA7    M1RGF2    H9J1Y0    B1Q141    + More
B3GEF6    B1Q137    H9IWJ7    H9IZW1    H9JF44    H9J066    H9J067    H9JDS4    H9IUE5    H9IWJ8   

Pfam

PF00135   COesterase

Interpro

IPR002018   CarbesteraseB        + More
IPR029058   AB_hydrolase       
IPR019826   Carboxylesterase_B_AS       
IPR000997   Cholinesterase       
IPR002168   Lipase_GDXG_HIS_AS       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JDS3   B1Q139   B8YPE7   A0A0L7L3V0   A0A2A4K075   A0A1U9X1V1   + More
A0A2A4JZ33   A0A1U9X1V6   A0A194PEF7   A0A2W1BQY3   A0A194Q254   D5G3E0   H9IUA7   A0A0N1PJ90   A0A194Q887   A0A0N1IPF0   M1RGF2   H9J1Y0   B1Q141   A0A2I6RJM2   A0A194PDI7   B3GEF6   A0A2H1VAI9   A0A1U9X1V3   A0A2H1VAJ0   A0A0L7L0K6   A0A212FJ60   A0A0B4RXS5   A0A194RIH0   A0A0N1IGW1   A0A437AWV6   A0A3S2LSF5   A0A194Q249   A0A194PJ15   B1Q137   A0A2A4JR93   A0A194Q2Q8   A0A2H1WRP2   A0A212FJ67   A0A1U9X1V0   A0A1U9X1Z0   A0A3G1T174   A0A2A4JU91   A0A2W1BZX4   A0A2H1VEA4   A0A2H1VCN6   A0A2H1VCP0   A0A2H1VCN0   A0A2A4K7E9   A0A1U9X1U7   H9IWJ7   A0A0L7LED6   D5G3E3   A0A2W1BTR6   A0A2H1VCT7   A0A2H1VCQ9   H9IZW1   H9JF44   D5G3E2   D5G3E1   A0A3S2NSH9   A0A2H1VCR3   H9J066   H9J067   A0A0L7KY57   A0A2H1VCT9   A0A0L7L1R0   A0A0C5BXH5   A0A2H1WHB4   H9JDS4   A0A2A4JYV0   A0A1U9X1X9   A0A194QYN7   A0A2H1VCP9   D5G3E4   A0A2A4JSH8   A0A2W1BXP7   A0A2W1BVP4   A0A2W1BNW5   A0A2W1BTK5   A0A0F7QHL9   A0A194PD51   A0A1U9X1Z4   A4UA26   A0A212FJ53   A0A2A4JU71   A0A2A4JU07   A0A2W1BJM9   A0A2A4JHL2   H9IUE5   A0A0K0XRM2   A0A0C5C1P7   A0A2H1VH39   A0A212EY53   D3GDM3   A0A0L7KQ39   A0A0B4RY83   H9IWJ8   A0A1U9X1U4   A0A0L7LKE5  

PDB

1JMY     E-value=3.35565e-35,     Score=373

KEGG

100144577    no KO assigned | (RefSeq) ae25, Bmae25, Care-9; carboxylesterase CarE-9

GO

GO:0016021   GO:0016787   GO:0004104   GO:0080030  

SignalP

Position:   1 - 23,         Likelihood:  0.533318

 

 

Length:

559

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.57596

Exp number, first 60 AAs:

21.91136

Total prob of N-in:

0.99528

POSSIBLE N-term signal

sequence

inside

1  -  10

TMhelix

11  -  33

outside

34  -  559

 

 

Pi

47.117103

Theta

172.302089

Tajima's D

-1.390984

CLR

300.030923

CSRT

0.0755462226888656

Interpretation

Uncertain