Gene

KWMTBOMO08716  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007919

Annotation

PREDICTED:_estradiol_17-beta-dehydrogenase_8-like_[Plutella_xylostella]

Location

Bomo_Chr15(-):3443223-3447964      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 1.656

CDS

ATGGTGTCGGGTTTAGTAGTAGGTCGCCTTGCTCTCGTTACTGGTGCCGGTTCTGGGATTGGTCGTGCAGCGTGCCAAGTTTTATCAAAAGAGGGAGCCACTGTGATAGCCGCAGACAGGAAGTATGAAGCTGCTGTACAAACTATAAAAACTCATACAGCATTAGCACCTGGTACTAATGGTGGTGAGGAGCATAGTGCTGTGGAATTAGACGTTTCCAACAGTAAAGCAGTCCAAGACCTGGTACAAGATACACTGAAGCAATATAAAAAGCCTCCTTGCATCATTGTCAACTCTGCCGGCATTACCAGGGATAATTGGATGCTGAAACTCTCAGAGGAAGACTATGATAGTGTGCTTAATGTAAACTTGAAGGGTACATTCTTAGTGATGCAGGCATTTGCAAAAGCGATGGCCGAGTCGTCAGTGACGGGTTCTATAATAAATATCTCTAGCATTGTTGGAAAATACGGAAACATGGGGCAGACAAACTATGCGAGTAGTAAGGCTGGAGTGGTCGCGATGACTCAATCCGCAGCCAAGGAGTTAGGAAAATTCAACATAAGGGTGAACGCAATCTTACCTGGATTCATTGACACACCGATAATAAAAACAGTCCCTGACAAAGTCAAGGAACAGATTGTGAAATTAGTCCCACTAGGACGACTCGGTAATCCTGCAGAAGTTGCAGAGGTAATCGCCTTCTTAAGTTCCGACAAGAGCTCTTTCATCACTGGTGCTGCTATTGACGTCAGTGGAGGGTATTAA

Protein

MVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKVKEQIVKLVPLGRLGNPAEVAEVIAFLSSDKSSFITGAAIDVSGGY

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Uniprot

H9JEH2   A0A212F641   A0A2H1WGJ6   A0A3S2LT13   I4DL53   A0A194QNS9   + More
A0A2W1BL92   A0A194PWD0   A0A194QSW4   A0A2A4K4U4   A0A1L8DIW5   B4MCS4   B3MWD6   A0A1B0CE30   B4JJG0   A0A034WJ56   A0A1Y1MUQ4   A0A0K8U1E6   A0A0M4EMA7   D6X4G4   C0MM13   Q9W4U2   A0A0A1X145   A0A0B4J2T3   A0A195D3T0   A0A336M7G9   W8BRS7   A0A1I8Q7M2   A0A182GXJ0   A0A3B0K2R8   B4NDX7   B0W411   A0A1W4VRX8   A0A1I8Q7Q6   A0A182IW82   T1PGG1   B3NTZ1   A0A1I8N8R6   Q29HP4   B4L898   B4Q0U0   A0A232EGH7   A0A182Y8C7   B4R3V9   A0A023EN08   A0A1A9WL56   F4WKF5   A0A182XCE5   A0A182P1P4   A0A0L0C162   B4F625   A0A182L644   Q7Q1U0   A0A182ICQ7   A0A1Y1MN79   A0A182VTU3   A0A182U884   A0A182RGN2   A0A0K8WKQ7   B4IA21   A0A182MT92   A0A195DI61   A0A2A3EHF5   A0A084W1Y8   A0A2C9M9K3   A0A1I8JSL7   B4F631   A0A0M9A8F6   A0A182K4D5   A0A182SDD6   Q561S1   A0A182QC50   A0A2M4BY11   U5EVE1   W5J9L5   A0A1J1IMH0   J9I050   Q1LWX6   Q16F48   A0A2R7W0D0   V5GJ58   A0A2M3ZDI3   A0A195EQN1   A0A0L8GCE7   A0A2B4RVX5   A0A182NB02   E2B9T1   Q8AW16   A0A1S3H855   A7RXH2   A0A336K5N9   A0A0T6AYX8   A0A1S3JCP3   A0A3M6U1E4   A0A1B0G0Y9   A0A2M4AVP4   A0A2J7PQF3   A0A310SLF4   D3TL56   A0A158NQM7  

Pubmed

19121390    22118469    22651552    26354079    28756777    17994087    + More
25348373    28004739    18362917    19820115    19126864    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25830018    20075255    24495485    26483478    25315136    15632085    17550304    28648823    25244985    24945155    21719571    26108605    18477586    20966253    12364791    14747013    17210077    24438588    15562597    20920257    23761445    17510324    23594743    20798317    17615350    26383154    30382153    20353571    21347285   

EMBL

BABH01003078    BABH01003079    AGBW02010081    OWR49198.1    ODYU01008518    SOQ52190.1    + More
RSAL01000014    RVE53231.1    AK402021    BAM18643.1    KQ461195    KPJ06630.1    KZ150012    PZC75051.1    KQ459596    KPI95440.1    KPJ06631.1    NWSH01000128    PCG79275.1    GFDF01007702    JAV06382.1    CH940660    EDW57996.1    CH902625    EDV34921.2    AJWK01008531    CH916370    EDV99712.1    GAKP01004792    JAC54160.1    GEZM01026257    JAV87087.1    GDHF01031993    JAI20321.1    CP012528    ALC48821.1    KQ971380    EEZ97555.1    FM246385    CAR94311.1    AE014298    AY113563    AAF45844.2    AAM29568.1    AGB95045.1    GBXI01009505    JAD04787.1    AAZX01000353    KQ976885    KYN07511.1    UFQS01001153    UFQT01000663    UFQT01000664    UFQT01001153    SSX09275.1    SSX26264.1    SSX26265.1    GAMC01006962    JAB99593.1    JXUM01020458    JXUM01034336    JXUM01034337    KQ561020    KQ560572    KXJ80008.1    KXJ81856.1    OUUW01000015    SPP88524.1    CH964239    EDW81946.1    DS231834    EDS32604.1    KA647892    AFP62521.1    CH954180    EDV45699.1    CH379064    EAL31714.4    CH933814    EDW05673.1    CM000162    EDX01307.1    NNAY01004762    OXU17453.1    CM000366    EDX16971.1    GAPW01003338    JAC10260.1    GL888199    EGI65293.1    JRES01001043    KNC26001.1    AM999261    AM999262    AM999263    AM999264    AM999265    AM999266    AM999268    FM246374    FM246375    FM246376    FM246377    FM246378    FM246379    FM246380    FM246381    FM246382    FM246383    FM246384    CAQ53623.1    CAQ53624.1    CAQ53625.1    CAQ53626.1    CAQ53627.1    CAQ53628.1    CAQ53630.1    CAR94300.1    CAR94301.1    CAR94302.1    CAR94303.1    CAR94304.1    CAR94305.1    CAR94306.1    CAR94307.1    CAR94308.1    CAR94309.1    CAR94310.1    AAAB01008980    EAA13862.3    APCN01005749    GEZM01026255    JAV87089.1    GDHF01000632    JAI51682.1    CH480825    EDW44052.1    AXCM01006310    KQ980824    KYN12522.1    KZ288256    PBC30606.1    ATLV01019471    KE525272    KFB44232.1    AM999267    CAQ53629.1    KQ435712    KOX79360.1    BC093373    AAH93373.1    AXCN02000649    GGFJ01008753    MBW57894.1    GANO01001899    JAB57972.1    ADMH02001879    ETN60691.1    CVRI01000054    CRL00756.1    CH478512    EJY58115.1    FP085392    BX510994    CAK04961.1    EAT32860.1    KK854215    PTY13203.1    GALX01004362    JAB64104.1    GGFM01005800    MBW26551.1    KQ982021    KYN30585.1    KQ422595    KOF74613.1    LSMT01000315    PFX20487.1    GL446605    EFN87518.1    AL672176    CAD54662.1    DS469550    EDO43775.1    UFQS01000135    UFQT01000135    SSX00286.1    SSX20666.1    LJIG01022498    KRT80258.1    RCHS01002437    RMX47344.1    CCAG010003430    GGFK01011520    MBW44841.1    NEVH01022638    PNF18567.1    KQ760132    OAD61804.1    EZ422156    ADD18351.1    ADTU01023414   

Proteomes

UP000005204    UP000007151    UP000283053    UP000053240    UP000053268    UP000218220    + More
UP000008792    UP000007801    UP000092461    UP000001070    UP000092553    UP000007266    UP000000803    UP000002358    UP000078542    UP000095300    UP000069940    UP000249989    UP000268350    UP000007798    UP000002320    UP000192221    UP000075880    UP000008711    UP000095301    UP000001819    UP000009192    UP000002282    UP000215335    UP000076408    UP000000304    UP000091820    UP000007755    UP000076407    UP000075885    UP000037069    UP000075882    UP000007062    UP000075840    UP000075920    UP000075902    UP000075900    UP000001292    UP000075883    UP000078492    UP000242457    UP000030765    UP000076420    UP000069272    UP000053105    UP000075881    UP000075901    UP000075886    UP000000673    UP000183832    UP000008820    UP000000437    UP000078541    UP000053454    UP000225706    UP000075884    UP000008237    UP000085678    UP000001593    UP000275408    UP000092444    UP000235965    UP000005205   

PRIDE

H9JEH2    C0MM13    Q9W4U2   

Pfam

PF00010   HLH        + More
PF00106   adh_short

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR002347   SDR_fam       
IPR020904   Sc_DH/Rdtase_CS       
IPR011598   bHLH_dom       
IPR036638   HLH_DNA-bd_sf       

SUPFAM

SSF51735   SSF51735        + More
SSF47459   SSF47459       

Gene 3D

4.10.280.10    

CDD

cd00083  HLH

ProteinModelPortal

H9JEH2   A0A212F641   A0A2H1WGJ6   A0A3S2LT13   I4DL53   A0A194QNS9   + More
A0A2W1BL92   A0A194PWD0   A0A194QSW4   A0A2A4K4U4   A0A1L8DIW5   B4MCS4   B3MWD6   A0A1B0CE30   B4JJG0   A0A034WJ56   A0A1Y1MUQ4   A0A0K8U1E6   A0A0M4EMA7   D6X4G4   C0MM13   Q9W4U2   A0A0A1X145   A0A0B4J2T3   A0A195D3T0   A0A336M7G9   W8BRS7   A0A1I8Q7M2   A0A182GXJ0   A0A3B0K2R8   B4NDX7   B0W411   A0A1W4VRX8   A0A1I8Q7Q6   A0A182IW82   T1PGG1   B3NTZ1   A0A1I8N8R6   Q29HP4   B4L898   B4Q0U0   A0A232EGH7   A0A182Y8C7   B4R3V9   A0A023EN08   A0A1A9WL56   F4WKF5   A0A182XCE5   A0A182P1P4   A0A0L0C162   B4F625   A0A182L644   Q7Q1U0   A0A182ICQ7   A0A1Y1MN79   A0A182VTU3   A0A182U884   A0A182RGN2   A0A0K8WKQ7   B4IA21   A0A182MT92   A0A195DI61   A0A2A3EHF5   A0A084W1Y8   A0A2C9M9K3   A0A1I8JSL7   B4F631   A0A0M9A8F6   A0A182K4D5   A0A182SDD6   Q561S1   A0A182QC50   A0A2M4BY11   U5EVE1   W5J9L5   A0A1J1IMH0   J9I050   Q1LWX6   Q16F48   A0A2R7W0D0   V5GJ58   A0A2M3ZDI3   A0A195EQN1   A0A0L8GCE7   A0A2B4RVX5   A0A182NB02   E2B9T1   Q8AW16   A0A1S3H855   A7RXH2   A0A336K5N9   A0A0T6AYX8   A0A1S3JCP3   A0A3M6U1E4   A0A1B0G0Y9   A0A2M4AVP4   A0A2J7PQF3   A0A310SLF4   D3TL56   A0A158NQM7  

PDB

2PD6     E-value=9.32658e-64,     Score=615

KEGG

101742305    K13370 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-ox

PATHWAY

00061    Fatty acid biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0016491   GO:0003857   GO:0004303   GO:0046983   GO:0016616   GO:0055114   GO:0005739   GO:0006508   GO:0008061   GO:0046872   GO:0007219   GO:0007275   GO:0050793   GO:0003676   GO:0016876   GO:0043039  

Length:

255

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.29637

Exp number, first 60 AAs:

0.21294

Total prob of N-in:

0.01988

outside

1  -  255

 

 

Pi

274.829566

Theta

180.531339

Tajima's D

1.287957

CLR

12.273281

CSRT

0.733063346832658

Interpretation

Uncertain