Gene

KWMTBOMO08714

Pre Gene Modal

BGIBMGA007668

Annotation

PREDICTED:_chymotrypsin-2-like_[Amyelois_transitella]

Location

Bomo_Chr15(+):3419045-3424044      View in EpiBrowser

Full name

Chymotrypsin-2      

Alternative Name

AnChym2

Location in the cell

Extracellular   Reliability : 2.686

CDS

ATGTCACAGGATTCACCACGAGTGGTAGGCGGTGTGACTGTACCAGATGGTCGTATCCCTTATCAGGCGTCTCTGCGAACACTCTTCAATTCTCACTTTTGTGGCGGAAGTATCCTTAACGAGAAATGGGTCTTGACTGCCGCGCACTGTACTGTTGGCCAATCACATTTGACAATGCAAGTTGTGGTTGGAACAAACAATCTCCACATAGGCGGCGAGCACCACTCCGTCGAGTCGATCATCATACATAGTGACTACAACAGCATGGCCATCAGCAATGACGTCAGCCTGGTGAAGGTATCTAATGACATCGTGTTCAATGATAACGTTCAGTCAATACAACTGCCTGACGATGACACGGACGTCGGAGCTGACGTCATGCTGAGTGGGTGGGGGAGACTTTCGTATCCAGGGGTATACCCCAATCACCTGCAAATGCTAAATCTAACATCTCTGAGTGTGGAGCTATGCCAGGATATCTTCGTTGGCATCAACCCTGTATTCTCGACTCAGATATGCGCCATGACCAAGGTTGGAGAAGGAGCATGCCACGGCGATTCTGGTGGTCCGTTGGTGGAAGGAAACACGGTGGTGGGCGTGGTGTCCTGGGGTATGCCCTGTGCTCGTGGCTACCCTGATGTATACTCAAGGGTCTTCGCATTTAAAGACTGGATATTGGAGAAAATGGAACAAAACTAA

Protein

MSQDSPRVVGGVTVPDGRIPYQASLRTLFNSHFCGGSILNEKWVLTAAHCTVGQSHLTMQVVVGTNNLHIGGEHHSVESIIIHSDYNSMAISNDVSLVKVSNDIVFNDNVQSIQLPDDDTDVGADVMLSGWGRLSYPGVYPNHLQMLNLTSLSVELCQDIFVGINPVFSTQICAMTKVGEGACHGDSGGPLVEGNTVVGVVSWGMPCARGYPDVYSRVFAFKDWILEKMEQN

Catalytic Activity

Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Complete proteome   Digestion   Disulfide bond   Hydrolase   Protease   Reference proteome   Secreted   Serine protease   Signal   Zymogen  

Feature

propeptide  Activation peptide
chain  Chymotrypsin-2

Uniprot

H9JDS1   A0A2W1BJK4   A0A2A4K680   A0A3S2P5Y9   A0A194QMQ6   A0A194PRR2   + More
A0A212F636   A0A212F633   A0A3S2TRK4   A0A2H1WU74   K7IRM7   A0A2A4JXA5   A0A2W1BDL5   A0A212ELH6   K7IMT5   A0A087ZQ85   A0A3S2NS83   K7IMT7   A0A2A3EKL4   K7IMT4   A0A0M9A2K3   A0A2H1WEZ5   K7IMT3   A0A0N1PJ78   A0A154P3U3   A0A195BZ04   A0A158P3L4   A0A158P3L3   A0A151IHB1   A0A0J7KPH6   A0A232EZ15   A0A194PZ53   E2ACM3   A0A026WVM2   A0A232EXJ7   D0R8Q9   H9JWP8   D6WK62   A0A1Y1MAP6   Q17IG9   A0A0L7R485   A0A151XG10   Q175P6   A0A232FHI8   D0R8R4   Q8T639   A0A023EMN4   A0A1Q3FSI0   A0A195F0A9   A0A1W7R7W0   W5JMT6   O97099   A0A151IT67   T1DGK1   A0A1Y1MKE8   Q9NGY6   A0A1J1HSC6   A0A336MC30   A0A1B0CGA7   A0A182JLT2   A0A1B0DFH7   A0A182UFJ4   B0WLB8   Q5TWQ5   A0A182KQG2   A0A2C9GS03   A0A182GGY4   A0A182VGU5   A0A1W7R806   A0A1B0GHG0   B0WAK4   A0A1B0DDL4   A0A1Q3FNV0   D0V550   A0A336M0L8   A0A1J1IR33   A0A1I8MI67   A0A0M5JCH1   A0A232FJD4   W5JVV6   O97097   A0A1S4FE82   A0A154P6Q3   K7J5P6   Q175L8   A0A182QXH3   O97100   Q16NM7   A0A0C9R4S6   Q9XY45   E9J8Q2   B0WHA0   A0A0U1Z1T2   A0A2C9GRR7   A0A182VP77   Q7QIZ2   Q17025   Q5TWE1   Q175P5   A0A182KLE4  

EC Number

3.4.21.1

Pubmed

19121390    28756777    26354079    22118469    20075255    21347285    + More
28648823    20798317    24508170    30249741    18362917    19820115    28004739    17510324    24945155    20920257    23761445    12609516    12364791    14747013    17210077    20966253    26483478    20017753    25315136    21282665    25749759    11453997   

EMBL

BABH01003079    KZ150012    PZC75048.1    NWSH01000128    PCG79273.1    RSAL01000014    + More
RVE53228.1    KQ461195    KPJ06629.1    KQ459596    KPI95439.1    AGBW02010081    OWR49200.1    OWR49201.1    RVE53229.1    ODYU01011093    SOQ56615.1    NWSH01000497    PCG76022.1    KZ150244    PZC71884.1    AGBW02014066    OWR42328.1    RSAL01000269    RVE43195.1    KZ288229    PBC31726.1    KQ435756    KOX75917.1    ODYU01007885    SOQ51044.1    KQ460599    KPJ13815.1    KQ434809    KZC06605.1    KQ976394    KYM93148.1    ADTU01008199    KQ977636    KYN01157.1    LBMM01004589    KMQ92263.1    NNAY01001573    OXU23549.1    KQ459583    KPI98612.1    GL438568    EFN68767.1    KK107109    QOIP01000008    EZA59134.1    RLU19794.1    NNAY01001736    OXU23082.1    FN547058    KQ971342    CBC01166.1    EFA04659.1    BABH01018411    EFA04622.1    GEZM01036400    GEZM01036398    GEZM01036395    GEZM01036393    GEZM01036392    GEZM01036391    JAV82733.1    CH477239    EAT46500.1    KQ414658    KOC65663.1    KQ982174    KYQ59316.1    CH477397    EAT41804.1    NNAY01000219    OXU29928.1    FN547063    CBC01177.1    AF487334    AAL93243.1    GAPW01003508    JAC10090.1    GFDL01004672    JAV30373.1    KQ981880    KYN33913.1    GEHC01000393    JAV47252.1    ADMH02001109    ETN64084.1    AF051780    AAD17493.1    KQ981039    KYN10142.1    GAMD01002746    JAA98844.1    GEZM01028907    JAV86199.1    AF237415    AAF43707.1    CVRI01000012    CRK89382.1    UFQT01000369    SSX23608.1    AJWK01010930    AJWK01010931    AJWK01010932    AJVK01005806    DS232962    DS231983    EDS27062.1    EDS30402.1    AAAB01008807    EAL41865.3    APCN01000169    JXUM01062824    KQ562217    KXJ76377.1    GEHC01000378    JAV47267.1    AJWK01004566    DS231873    EDS41558.1    AJVK01005414    GFDL01005774    JAV29271.1    GU018015    ACY24348.1    SSX23610.1    CVRI01000058    CRL02608.1    CP012526    ALC46481.1    NNAY01000131    OXU30693.1    ADMH02000310    ETN67024.1    AF051778    AAD17491.1    KQ434827    KZC07503.1    CH477398    EAT41784.1    AXCN02000582    AF051781    AAD17494.1    CH477816    EAT35957.1    EAT35958.1    GBYB01001836    JAG71603.1    AF053903    AAD21823.1    GL769036    EFZ10800.1    DS231933    EDS27558.1    KJ801816    AJO53282.1    EAA04161.3    Z18888    Z32645    EAL41979.1    EAT41805.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000053268    UP000007151    + More
UP000002358    UP000005203    UP000242457    UP000053105    UP000076502    UP000078540    UP000005205    UP000078542    UP000036403    UP000215335    UP000000311    UP000053097    UP000279307    UP000007266    UP000008820    UP000053825    UP000075809    UP000078541    UP000000673    UP000078492    UP000183832    UP000092461    UP000075880    UP000092462    UP000075902    UP000002320    UP000007062    UP000075882    UP000075840    UP000069940    UP000249989    UP000075903    UP000095301    UP000092553    UP000075886   

PRIDE

H9JDS1    H9JWP8   

Pfam

PF00089   Trypsin

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR001254   Trypsin_dom       
IPR033116   TRYPSIN_SER       
IPR018114   TRYPSIN_HIS       
IPR012224   Pept_S1A_FX       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JDS1   A0A2W1BJK4   A0A2A4K680   A0A3S2P5Y9   A0A194QMQ6   A0A194PRR2   + More
A0A212F636   A0A212F633   A0A3S2TRK4   A0A2H1WU74   K7IRM7   A0A2A4JXA5   A0A2W1BDL5   A0A212ELH6   K7IMT5   A0A087ZQ85   A0A3S2NS83   K7IMT7   A0A2A3EKL4   K7IMT4   A0A0M9A2K3   A0A2H1WEZ5   K7IMT3   A0A0N1PJ78   A0A154P3U3   A0A195BZ04   A0A158P3L4   A0A158P3L3   A0A151IHB1   A0A0J7KPH6   A0A232EZ15   A0A194PZ53   E2ACM3   A0A026WVM2   A0A232EXJ7   D0R8Q9   H9JWP8   D6WK62   A0A1Y1MAP6   Q17IG9   A0A0L7R485   A0A151XG10   Q175P6   A0A232FHI8   D0R8R4   Q8T639   A0A023EMN4   A0A1Q3FSI0   A0A195F0A9   A0A1W7R7W0   W5JMT6   O97099   A0A151IT67   T1DGK1   A0A1Y1MKE8   Q9NGY6   A0A1J1HSC6   A0A336MC30   A0A1B0CGA7   A0A182JLT2   A0A1B0DFH7   A0A182UFJ4   B0WLB8   Q5TWQ5   A0A182KQG2   A0A2C9GS03   A0A182GGY4   A0A182VGU5   A0A1W7R806   A0A1B0GHG0   B0WAK4   A0A1B0DDL4   A0A1Q3FNV0   D0V550   A0A336M0L8   A0A1J1IR33   A0A1I8MI67   A0A0M5JCH1   A0A232FJD4   W5JVV6   O97097   A0A1S4FE82   A0A154P6Q3   K7J5P6   Q175L8   A0A182QXH3   O97100   Q16NM7   A0A0C9R4S6   Q9XY45   E9J8Q2   B0WHA0   A0A0U1Z1T2   A0A2C9GRR7   A0A182VP77   Q7QIZ2   Q17025   Q5TWE1   Q175P5   A0A182KLE4  

PDB

1EQ9     E-value=5.08642e-45,     Score=453

KEGG

101740646    K01312 trypsin [EC:3.4.21.4] | (RefSeq) chymotrypsin-2-like

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0004252   GO:0008236   GO:0016021   GO:0007596   GO:0005509   GO:0007586   GO:0005576   GO:0006508   GO:0008061   GO:0046872   GO:0007219   GO:0007275   GO:0050793   GO:0003676   GO:0016876   GO:0043039  

Subcellular location

Secreted  

Length:

232

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01209

Exp number, first 60 AAs:

0.00317

Total prob of N-in:

0.05728

outside

1  -  232

 

 

Pi

185.494567

Theta

152.31005

Tajima's D

0.575936

CLR

0.071011

CSRT

0.536523173841308

Interpretation

Uncertain