Gene

KWMTBOMO08703

Pre Gene Modal

BGIBMGA007924

Annotation

PREDICTED:_fizzy-related_protein_homolog_[Papilio_machaon]

Location

Bomo_Chr15(-):3001371-3055553      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.008 Nuclear   Reliability : 2.105

CDS

ATGTTCAGTAAACATTATGAGACTCGGTTACTACAGCAGTGCAGTCCTGTGGCAAGGAAACAGTCTGTACTGGTCCAGGCTGAGTTTAACAATGGTGACAGGTTCACACCCTGCAGAGCTGGAAACAATTGGCAGACAGCTTTTCAAGCACTAAGAAGAGGTACGGAAAATCAACCAGCAAAGAAGGCGCGAAACGATGGCGGTGGCAGCGACGGAGCGAGTGGCGGTCGAGACCAGCTCGCTTACAGCTGCCTCCTACAGAACGAACTCCTCGGTGCACAGATAGAGGAAGTCAGGAATCCATCGGCGACGTGTCCGGATGGCAACAAGACTATCGGCACCGTCCAGACGCCTGGCAGATCGTCGCAAGCTTACCAACCGGTCTTCAGATTCAAAGCGCCGATCCACAGAGCAGAGGAAAACATTGATCCTTCGCCGTACAGCCTGTCCCCGATCTCGGCTAAATCCGAGAAGCTTCTCCGGTCCCCAAGGAAGGCGACCCGCAAGATATCGCGGATCCCGTTCAAGGTTCTGGACGCGCCGGAGTTGCAGGACGACTTCTACCTGAACCTGGTCGACTGGTCCGCCCAGAACGTGCTCAGCGTCGGCCTCGGGAGCTGCGTCTACTTGTGGAGCGCCTGCACCAGTCAGGTGACGCGGTTATGTGACCTGTCAACGGAAGGTAACGCGGTGACTTCGGTGGCGTGGAGCGAACGCGGCCACCTCGTCGCCGTCGGGACGCAGAAGGGGCACATCAGCGTGTGGGACGTTGCCGTCAACAAGGAGGTGACGAAGCTCCAAGGTCACATAGCGCGCGTCGGAGCCCTCGCCTGGAACGGTGACATACTCAGCTCAGGGTCCAGGGACCGACACATCCGCCAGCGGGACACCAGAACGCCACCGATACAACTCTCCCGAGTTCTCCAAGGTCACAGACAAGAGGTCTGCGGCCTGAAGTGGTCGCCCGACGGCCAATCGTTGGCTTCAGGAGGCAACGACAACAAGCTCTTCGTTTGGTCGATGCACTCGACGTCGCCGGTGCAGACGTACTCCGCGCACGTGGCGGCCGTGAAGGCGATCGCTTGGTCGCCGCACCAGCACGGGCTGCTCGCGTCCGGCGGCGGCACGGCGGACCGCTGCATACGCTTCTGGAACACGCTCACCTCGCAGCCGATGCAGTGCGTCGACACCGGATCTCAAGTGTGCAACTTGGCTTGGTCGAAACACTCCAGCGAGTTGGTCTCGACTCACGGCTACTCACAGAACCAGATACTGGTGTGGAAATATCCGTCGTTGACGCAGGTGGCGAAACTGACTGGCCATTCCTATCGAGTTCTGTACTTGGCTCTATCACCGGACGGCGAGGCCATCGTCACGGGAGCCGGTGACGAAACGCTTCGGTTCTGGAATGTTTTCTCCAAAACGCCCTCACACAAGGAGAACAAGAGCGTCCTAAACCTATACACCGCACTCAGATAA

Protein

MFSKHYETRLLQQCSPVARKQSVLVQAEFNNGDRFTPCRAGNNWQTAFQALRRGTENQPAKKARNDGGGSDGASGGRDQLAYSCLLQNELLGAQIEEVRNPSATCPDGNKTIGTVQTPGRSSQAYQPVFRFKAPIHRAEENIDPSPYSLSPISAKSEKLLRSPRKATRKISRIPFKVLDAPELQDDFYLNLVDWSAQNVLSVGLGSCVYLWSACTSQVTRLCDLSTEGNAVTSVAWSERGHLVAVGTQKGHISVWDVAVNKEVTKLQGHIARVGALAWNGDILSSGSRDRHIRQRDTRTPPIQLSRVLQGHRQEVCGLKWSPDGQSLASGGNDNKLFVWSMHSTSPVQTYSAHVAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTSQPMQCVDTGSQVCNLAWSKHSSELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLALSPDGEAIVTGAGDETLRFWNVFSKTPSHKENKSVLNLYTALR

Cofactor

Mg(2+)

Similarity

Belongs to the PP2C family.

Uniprot

A0A2W1BCE8   A0A3S2NKX6   A0A212EMH9   A0A2A4JW45   A0A194RAM3   H9JEH7   + More
U5EV22   A0A1I8MAB3   W8ASZ3   A0A1J1HT88   A0A0K8U1X0   Q17CQ5   A0A034VNG0   A0A023ESV6   A0A1Q3G3M5   A0A0A1X5L9   A0A3B0J7B4   Q29G84   B3MS79   B3NU56   A0A1I8NTT0   A0A1W4U5T1   B4L2J6   A0A0M3QZI0   B4NC43   B4R4P5   Q9W4H9   B4Q032   O18402   B4M7U0   B4JX77   A0A336LNN7   A0A182JCA7   A0A340TBF7   A0A182QYL6   A0A232FJF8   Q7PUU4   A0A2J7R4N4   K7ILS6   D6W9Q9   A0A1B6DR46   B4I0W3   A0A195DSV1   F4X2K7   A0A195BT79   A0A195FX20   A0A158NVA2   A0A1B0DPN4   A0A151IBE6   A0A1L8DX39   A0A026WBU6   A0A151WFR8   A0A3L8DNK8   M9PLJ4   E2B214   A0A291S6V5   A0A154PKT1   A0A2A3E3W2   A0A0J7L699   A0A087ZZZ4   E9IVM5   D1LX13   A0A3Q0IXN9   H3A259   E2B8G8   A0A2P8YUD0   A0A0L7R3J1   A0A444TLK5   U6CVQ8   M3XXP4   A0A0C9RIT7   A0A2Y9L6R5   A0A3Q3RQJ7   A0A340XFY9   A0A2Y9M2B6   A0A2K6FS10   A0A0P6J296   A0A091DEE4   A0A286XCI2   A0A341B2D0   A0A3Q7UP78   A0A287D3A8   L5L806   A0A452EMH9   A0A3Q7NB01   A0A2Y9TKN2   A0A2Y9I9T1   A0A337SP30   A0A2U3Y4Y4   W5PSG6   A0A2U3VKG9   A0A212D207   A0A452RRH7   Q5H7B9   Q32L05   A0A250Y1W1   K9ILH8   H0XAM8   A0A383ZNB5   A0A3S3SIC5  

Pubmed

28756777    22118469    26354079    19121390    25315136    24495485    + More
17510324    25348373    24945155    25830018    15632085    17994087    23185243    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    9288747    28648823    12364791    14747013    17210077    20075255    18362917    19820115    21719571    21347285    24508170    30249741    25581109    20798317    28992199    21282665    9215903    29403074    21993624    23258410    17975172    20809919    30723633    19393038    28087693   

EMBL

KZ150142    PZC72932.1    RSAL01000051    RVE50207.1    AGBW02013840    OWR42679.1    + More
NWSH01000499    PCG76006.1    KQ460473    KPJ14549.1    BABH01003117    BABH01003118    GANO01001209    JAB58662.1    GAMC01017243    JAB89312.1    CVRI01000014    CRK89686.1    GDHF01031607    GDHF01019297    JAI20707.1    JAI33017.1    CH477305    EAT44141.1    GAKP01014938    GAKP01014937    GAKP01014936    GAKP01014935    JAC44014.1    GAPW01001226    JAC12372.1    GFDL01000637    JAV34408.1    GBXI01013813    GBXI01011330    GBXI01008329    JAD00479.1    JAD02962.1    JAD05963.1    OUUW01000003    SPP77675.1    CH379064    EAL32226.1    KRT07068.1    CH902622    EDV34634.1    CH954180    EDV45832.1    CH933810    EDW06872.1    CP012528    ALC49409.1    CH964239    EDW82402.1    CM000366    EDX17092.1    AE014298    BT001403    BT010011    AAF45973.1    AAN09125.1    AAN71158.1    AAQ22480.1    CM000162    EDX01184.1    Y14162    CAA74575.1    CH940653    EDW62857.1    CH916376    EDV95353.1    UFQT01000095    SSX19702.1    AXCN02000277    NNAY01000126    OXU30723.1    AAAB01008987    EAA00976.6    NEVH01007404    PNF35785.1    KQ971312    EEZ98532.1    GEDC01009156    JAS28142.1    CH480819    EDW53144.1    KQ980530    KYN15604.1    GL888584    EGI59332.1    KQ976417    KYM89883.1    KQ981193    KYN45200.1    ADTU01027051    AJVK01008173    AJVK01008174    AJVK01008175    AJVK01008176    KQ978106    KYM96972.1    GFDF01003105    JAV10979.1    KK107324    EZA52529.1    KQ983203    KYQ46694.1    QOIP01000006    RLU22030.1    KC437299    AGC79112.1    GL445031    EFN60270.1    MF432991    ATL75342.1    KQ434946    KZC12357.1    KZ288387    PBC26417.1    LBMM01000512    KMQ98176.1    GL766312    EFZ15378.1    GU075990    ACY92519.1    AFYH01102853    AFYH01102854    AFYH01102855    AFYH01102856    GL446332    EFN88002.1    PYGN01000354    PSN47858.1    KQ414663    KOC65398.1    SAUD01001885    RXG70856.1    HAAF01002989    CCP74815.1    AEYP01077183    GBYB01006811    JAG76578.1    GEBF01006300    JAN97332.1    KN122676    KFO28858.1    AAKN02057765    AGTP01068828    KB030265    ELK19376.1    LWLT01000008    AANG04002859    AMGL01091635    MKHE01000009    OWK12104.1    AEMK02000012    AB192874    DQIR01207158    DQIR01279121    BAD89277.1    HDB62635.1    BC109826    AAI09827.1    GFFV01002354    JAV37591.1    GABZ01005728    JAA47797.1    AAQR03058869    NCKU01000394    RWS15661.1   

Proteomes

UP000283053    UP000007151    UP000218220    UP000053240    UP000005204    UP000095301    + More
UP000183832    UP000008820    UP000268350    UP000001819    UP000007801    UP000008711    UP000095300    UP000192221    UP000009192    UP000092553    UP000007798    UP000000304    UP000000803    UP000002282    UP000008792    UP000001070    UP000075880    UP000075920    UP000075886    UP000215335    UP000007062    UP000235965    UP000002358    UP000007266    UP000001292    UP000078492    UP000007755    UP000078540    UP000078541    UP000005205    UP000092462    UP000078542    UP000053097    UP000075809    UP000279307    UP000000311    UP000076502    UP000242457    UP000036403    UP000005203    UP000079169    UP000008672    UP000008237    UP000245037    UP000053825    UP000288706    UP000000715    UP000248482    UP000261640    UP000265300    UP000248483    UP000233160    UP000028990    UP000005447    UP000252040    UP000286640    UP000005215    UP000010552    UP000291000    UP000286641    UP000248484    UP000248481    UP000011712    UP000245341    UP000002356    UP000245340    UP000291022    UP000008227    UP000009136    UP000005225    UP000261681    UP000285301   

PRIDE

H9JEH7    Q9W4H9    O18402   

Pfam

PF00400   WD40        + More
PF12894   ANAPC4_WD40
PF00481   PP2C

Interpro

IPR017986   WD40_repeat_dom        + More
IPR024977   Apc4_WD40_dom       
IPR001680   WD40_repeat       
IPR033010   Cdc20/Fizzy       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR001932   PPM-type_phosphatase_dom       
IPR000222   PP2C_BS       
IPR036457   PPM-type_dom_sf       
IPR011047   Quinoprotein_ADH-like_supfam       

SUPFAM

SSF50978   SSF50978        + More
SSF81606   SSF81606       
SSF50998   SSF50998       

Gene 3D

2.130.10.10     3.60.40.10    

CDD

cd00143  PP2Cc

ProteinModelPortal

A0A2W1BCE8   A0A3S2NKX6   A0A212EMH9   A0A2A4JW45   A0A194RAM3   H9JEH7   + More
U5EV22   A0A1I8MAB3   W8ASZ3   A0A1J1HT88   A0A0K8U1X0   Q17CQ5   A0A034VNG0   A0A023ESV6   A0A1Q3G3M5   A0A0A1X5L9   A0A3B0J7B4   Q29G84   B3MS79   B3NU56   A0A1I8NTT0   A0A1W4U5T1   B4L2J6   A0A0M3QZI0   B4NC43   B4R4P5   Q9W4H9   B4Q032   O18402   B4M7U0   B4JX77   A0A336LNN7   A0A182JCA7   A0A340TBF7   A0A182QYL6   A0A232FJF8   Q7PUU4   A0A2J7R4N4   K7ILS6   D6W9Q9   A0A1B6DR46   B4I0W3   A0A195DSV1   F4X2K7   A0A195BT79   A0A195FX20   A0A158NVA2   A0A1B0DPN4   A0A151IBE6   A0A1L8DX39   A0A026WBU6   A0A151WFR8   A0A3L8DNK8   M9PLJ4   E2B214   A0A291S6V5   A0A154PKT1   A0A2A3E3W2   A0A0J7L699   A0A087ZZZ4   E9IVM5   D1LX13   A0A3Q0IXN9   H3A259   E2B8G8   A0A2P8YUD0   A0A0L7R3J1   A0A444TLK5   U6CVQ8   M3XXP4   A0A0C9RIT7   A0A2Y9L6R5   A0A3Q3RQJ7   A0A340XFY9   A0A2Y9M2B6   A0A2K6FS10   A0A0P6J296   A0A091DEE4   A0A286XCI2   A0A341B2D0   A0A3Q7UP78   A0A287D3A8   L5L806   A0A452EMH9   A0A3Q7NB01   A0A2Y9TKN2   A0A2Y9I9T1   A0A337SP30   A0A2U3Y4Y4   W5PSG6   A0A2U3VKG9   A0A212D207   A0A452RRH7   Q5H7B9   Q32L05   A0A250Y1W1   K9ILH8   H0XAM8   A0A383ZNB5   A0A3S3SIC5  

PDB

5L9U     E-value=1.91276e-180,     Score=1625

KEGG

101743548    K03364 cell division cycle 20-like protein 1, cofactor of APC complex | (RefSeq) fizzy-related prote

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0097027   GO:0010997   GO:1904668   GO:0010001   GO:0008347   GO:0005819   GO:0005680   GO:0061630   GO:0005813   GO:0005814   GO:0031536   GO:0030424   GO:0001745   GO:0031145   GO:0007455   GO:0030163   GO:0005737   GO:0007088   GO:0004721   GO:0046872   GO:0040020   GO:0045732   GO:0031965   GO:0090344   GO:0070306   GO:0072425   GO:0005654   GO:0008284   GO:1904145   GO:0051301   GO:0005515   GO:0008270   GO:0003676   GO:0007219   GO:0007275   GO:0050793   GO:0016876   GO:0043039  

PANTHER

PTHR19918  

Length:

492

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01578

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00432

outside

1  -  492

 

 

Pi

252.63045

Theta

175.199766

Tajima's D

1.272913

CLR

0.079189

CSRT

0.735713214339283

Interpretation

Uncertain