Gene

KWMTBOMO08681

Pre Gene Modal

BGIBMGA007650

Annotation

PREDICTED:_piggyBac_transposable_element-derived_protein_3-like_[Papilio_xuthus]

Location

Bomo_Chr15(+):2114017-2115271      View in EpiBrowser

Full name

PiggyBac transposable element-derived protein 3       + More
Chimeric ERCC6-PGBD3 protein      
PiggyBac transposable element-derived protein 2      

Alternative Name

Chimeric CSB-PGBD3 protein

Location in the cell

Nuclear   Reliability : 4.12

CDS

ATGGCAAATGACAGACCGTTAGCTGCGCATGAAATTTTAGATGCTTTAGAAAATGTTTCTGATAATGAAGAAGATTATAGAGAACGACTGATATGTATTCTACCTCCTCCTGTTGATCCTGACTGTCTCACTGACGAAGATTCGGGTGAAGAAGATAATGTAACTTTGAATAATTTGCCACGAAACATTCTGCTTCAACCGGCTGAAGTAATGATTCAAGGGCAGATTATGGTGAGTGATACAGAAGAAGAACCTTCTGATTCTACAGGTCGAACTAAACGTAGGCGTACCTACGCATGGAGAAAACGGGACTTGGCAAAAAAACCCGTGAATTGGCCAGATGTTCAAGGCGCTTGCCAAGATAAGCGCCCAATTGAGTGGTTTGAAAACTTCTTAGATGAAGATGTTATTTCGTTGTTGGTGTCAGAGAGCAATAAATATGCTGTCAAAAAGAATTTGCCTGGAGACATAACCACTGAAGATATGAAATGTTTCATCGGCATATTGTTGGTTAGTGGTTATTCATGGCTCCCCCGTAGAAGAATGTATTGGGAAAACTCCCCTGATACAAAGAATGAATTGATCAGCTCGGCTATGACTAGGGATAGATTTGACTTTATTTTTCGCCACCTTCATGTCAATGATAATCTGGATTTGCAAGACAAATACACAAAAGTACGCCCCCTAGTTACACTTCTAAATAAAAAGTTCTTAGAGTTTTCTCCTCTTGAAGAGCATTACGGTGTAGATGAGGCCATGATCCCCTACATGGCTGCAAACAGCACATAA

Protein

MANDRPLAAHEILDALENVSDNEEDYRERLICILPPPVDPDCLTDEDSGEEDNVTLNNLPRNILLQPAEVMIQGQIMVSDTEEEPSDSTGRTKRRRTYAWRKRDLAKKPVNWPDVQGACQDKRPIEWFENFLDEDVISLLVSESNKYAVKKNLPGDITTEDMKCFIGILLVSGYSWLPRRRMYWENSPDTKNELISSAMTRDRFDFIFRHLHVNDNLDLQDKYTKVRPLVTLLNKKFLEFSPLEEHYGVDEAMIPYMAANST

Description

Binds in vitro to PGBD3-related transposable elements, called MER85s; these non-autonomous 140 bp elements are characterized by the presence of PGBD3 terminal inverted repeats and the absence of internal transposase ORF.
Involved in repair of DNA damage following UV irradiation, acting either in the absence of ERCC6 or synergistically with ERCC6. Involved in the regulation of gene expression. In the absence of ERCC6, induces the expression of genes characteristic of interferon-like antiviral responses. This response is almost completely suppressed in the presence of ERCC6. In the presence of ERCC6, regulates the expression of genes involved in metabolism regulation, including IGFBP5 and IGFBP7. In vitro binds to PGBD3-related transposable elements, called MER85s; these non-autonomous 140 bp elements are characterized by the presence of PGBD3 terminal inverted repeats and the absence of internal transposase ORF.

Miscellaneous

PGBD3 gene is located within ERCC6 intron 5.

Keywords

Alternative splicing   Complete proteome   DNA-binding   Nucleus   Phosphoprotein   Polymorphism   Reference proteome   Disease mutation   Isopeptide bond   Premature ovarian failure   Ubl conjugation  

Feature

chain  PiggyBac transposable element-derived protein 3
sequence variant  In dbSNP:rs4253072.
splice variant  In isoform 2.

Uniprot

A0A212FJ76   A0A3S2N5S4   A0A1A9Z8F7   A0A0A6ZDN2   H9JDQ3   A0A1B6HAI1   + More
A0A1Y1LG12   D7EK33   A0A1B6IG64   A0A1S3D993   T2M9K1   U3ENV5   U3B6D7   U3CPS9   U3E686   A0A2K5QFQ3   F6ZNL0   G3VIF3   A0A2K6ST22   F6RSP5   A0A2K5DEG0   F7EM96   A0A2K6E0X9   A0A147BBG9   A0A2J8RT17   Q8N328   A0A2J8JGQ8   A0A2K5JRR6   A0A2K5V985   A0A2K6E0V7   K7C897   A0A2R8Z9V9   A0A2K6PI71   A0A2K6LGX8   A0A096P4A2   A0A2K5LL76   A0A2K6AE02   M3XQ58   Q4R4A3   A0A2J8RT31   A0A2I3HPQ9   G3SEC0   A0A2K6F4D2   F7I1C5   P0DP91   A8K4Q3   A0A2I3RAX8   A0A2J8JGN8   A0A3P4RWH6   A0A2K6UA69   G5E5N2   A0A2Y9IGG0   A0A452DQQ1   S9WNB2   W5PEK4   A0A2Y9MDI9   A0A1B6JEF3   A0A2Y9MJ53   A0A212D1C8   A0A1B6JI72   A0A2Y9S0G5   A0A1S3F433   A0A341BW94   A0A341BUQ3   A0A2U4BI88   A0A2U4BIF0   A0A2K5KAR4   A0A2K5EST6   M3X8R6   A0A3Q2HLG4   F6X578   A0A336M992   A0A340X956   A0A383Z4K2   A0A2K5Q520   H0XRC8   A0A2K5Q526   A0A2K6PFT8   K7AM28   H2Q1I5   A0A2K6KZJ0   K9J215   A0A2J8RJL9   Q6P3X8   H2N335   G1QWB6   G1U4J0   B4DPA1   L8IPN2   G3RPE5   A0A2R9A3R8   K7CPY0   I3N029   G3SS70   A0A2R9A3S3   A0A2K6A111   A0A096N6I7   A0A2K5M1J2  

Pubmed

22118469    25515331    19121390    28004739    18362917    19820115    + More
24065732    25243066    17495919    21709235    17431167    25319552    29652888    14702039    15164054    15489334    18369450    22483866    23186163    26218421    16959974    22722832    25362486    15944441    22398555    17081983    16964243    18691976    18669648    20068231    21406692    28112733    11181995    16136131    19393038    23149746    20809919    17975172    19892987    17974005    16710414    21993624    22751099   

EMBL

AGBW02008302    OWR53786.1    RSAL01000353    RVE42252.1    JX294476    AGK25052.1    + More
BABH01003188    BABH01003189    GECU01036039    JAS71667.1    GEZM01060808    GEZM01060807    JAV70895.1    DS497727    EFA12977.1    GECU01021786    JAS85920.1    HAAD01002582    CDG68814.1    GAMP01000187    JAB52568.1    GAMT01003553    GAMT01003551    GAMQ01002282    JAB08308.1    JAB39569.1    GAMR01006104    JAB27828.1    GAMS01002010    JAB21126.1    AEFK01164926    AEFK01164927    JSUE03043349    JU470545    AFH27349.1    GEGO01007284    JAR88120.1    NDHI03003654    PNJ11666.1    AK074682    AL138760    BC028954    BC063690    NBAG03000461    PNI21937.1    AQIA01070964    GABF01001690    JAA20455.1    AHZZ02035229    AEYP01099555    AEYP01099556    AB179012    BAE02063.1    PNJ11664.1    PNJ11665.1    ADFV01105741    ADFV01105742    ADFV01105743    ADFV01105744    ADFV01105745    CABD030070918    GAMT01004683    GAMP01007477    JAB07178.1    JAB45278.1    BC034479    AK291018    CH471187    BAF83707.1    EAW93095.1    AACZ04060518    PNI21935.1    PNI21936.1    CYRY02043934    VCX38622.1    LWLT01000008    KB017432    EPY77693.1    AMGL01092670    GECU01010197    JAS97509.1    MKHE01000009    OWK12058.1    GECU01009093    JAS98613.1    AANG04001781    UFQT01000583    SSX25489.1    AAQR03188110    AACZ04070590    GABC01008499    GABE01003522    JAA02839.1    JAA41217.1    GABZ01005161    JAA48364.1    NDHI03003683    PNJ08718.1    AK123219    BX647065    AL672183    CH471257    BC063785    ABGA01061445    ABGA01061446    ABGA01061447    ADFV01037738    ADFV01037739    ADFV01037740    ADFV01037741    ADFV01037742    AK298248    BAG60513.1    JH880825    ELR58540.1    CABD030010211    CABD030010212    CABD030010213    GABF01004510    GABD01006865    NBAG03000628    JAA17635.1    JAA26235.1    PNI12914.1    AGTP01101535    AGTP01101536    AHZZ02018138   

Proteomes

UP000007151    UP000283053    UP000092445    UP000005204    UP000007266    UP000079169    + More
UP000233040    UP000002280    UP000007648    UP000233220    UP000008225    UP000233020    UP000006718    UP000233120    UP000005640    UP000233080    UP000233100    UP000240080    UP000233200    UP000233180    UP000028761    UP000233060    UP000233140    UP000000715    UP000001073    UP000001519    UP000233160    UP000002277    UP000009136    UP000248482    UP000291000    UP000002356    UP000248483    UP000248484    UP000081671    UP000252040    UP000245320    UP000011712    UP000002281    UP000265300    UP000261681    UP000005225    UP000001595    UP000001811    UP000005215    UP000007646   

PRIDE

H9JDQ3    Q8N328    P0DP91    A8K4Q3    Q6P3X8    B4DPA1    + More

Pfam

PF13843   DDE_Tnp_1_7

Interpro

IPR029526   PGBD       

ProteinModelPortal

A0A212FJ76   A0A3S2N5S4   A0A1A9Z8F7   A0A0A6ZDN2   H9JDQ3   A0A1B6HAI1   + More
A0A1Y1LG12   D7EK33   A0A1B6IG64   A0A1S3D993   T2M9K1   U3ENV5   U3B6D7   U3CPS9   U3E686   A0A2K5QFQ3   F6ZNL0   G3VIF3   A0A2K6ST22   F6RSP5   A0A2K5DEG0   F7EM96   A0A2K6E0X9   A0A147BBG9   A0A2J8RT17   Q8N328   A0A2J8JGQ8   A0A2K5JRR6   A0A2K5V985   A0A2K6E0V7   K7C897   A0A2R8Z9V9   A0A2K6PI71   A0A2K6LGX8   A0A096P4A2   A0A2K5LL76   A0A2K6AE02   M3XQ58   Q4R4A3   A0A2J8RT31   A0A2I3HPQ9   G3SEC0   A0A2K6F4D2   F7I1C5   P0DP91   A8K4Q3   A0A2I3RAX8   A0A2J8JGN8   A0A3P4RWH6   A0A2K6UA69   G5E5N2   A0A2Y9IGG0   A0A452DQQ1   S9WNB2   W5PEK4   A0A2Y9MDI9   A0A1B6JEF3   A0A2Y9MJ53   A0A212D1C8   A0A1B6JI72   A0A2Y9S0G5   A0A1S3F433   A0A341BW94   A0A341BUQ3   A0A2U4BI88   A0A2U4BIF0   A0A2K5KAR4   A0A2K5EST6   M3X8R6   A0A3Q2HLG4   F6X578   A0A336M992   A0A340X956   A0A383Z4K2   A0A2K5Q520   H0XRC8   A0A2K5Q526   A0A2K6PFT8   K7AM28   H2Q1I5   A0A2K6KZJ0   K9J215   A0A2J8RJL9   Q6P3X8   H2N335   G1QWB6   G1U4J0   B4DPA1   L8IPN2   G3RPE5   A0A2R9A3R8   K7CPY0   I3N029   G3SS70   A0A2R9A3S3   A0A2K6A111   A0A096N6I7   A0A2K5M1J2  

KEGG

105842020    no KO assigned | (RefSeq) piggyBac transposable element-derived protein 3-like

GO

GO:0016021   GO:0005654   GO:0016604   GO:0043565   GO:0010628   GO:0005634   GO:0045739   GO:0002230   GO:0033141  

Subcellular location

Nucleus  

Length:

262

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06178

Exp number, first 60 AAs:

0

Total prob of N-in:

0.05217

outside

1  -  262

 

 

Pi

245.257978

Theta

132.725268

Tajima's D

2.785913

CLR

0.335422

CSRT

0.966801659917004

Interpretation

Uncertain