Gene

KWMTBOMO08671  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007936

Annotation

PREDICTED:_uridine-cytidine_kinase_2_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr15(-):1879308-1895776      View in EpiBrowser

Full name

Uridine kinase      

Location in the cell

Cytoplasmic   Reliability : 1.555 Mitochondrial   Reliability : 1.255 Nuclear   Reliability : 1.43

CDS

ATGTCAATTTCAGCTGTGCTGCGAAATAGCCGGACGAGAGCTTTGTGTGTGCTTGTAGTCTTAAGAAAATCTGTTAGGTCATTTTACACGTACAAAATGGCAGAAAAACCAGCGGACTATTTATCGACAAATGGTTTCGAAAGTAAAACACCGTTCTTGATCGGTGTAGCTGGCGGCACAGCCAGTGGCAAGTCCACTGTATGCCAACGCATCATGGAGAAGCTTGGTCAGCAGCACAAAGAGCACACTGAAAGGCGAGTCGTCTGCATCAGCCAAGATTCCTTCTACAGAAGTCTGACAGCACCAGAACGTCTCCGAGCTGAACGTGGACAATTCAACTTTGATCATCCTGATGCATTTGATGACAAGAAACTGCTAGCAACATTAAAGGACATATTGGCAGGAAAGAAAGTTGAAATTCCTGAATATGATTACATCTCAAATTCAATAAGCAATCGCACAAACACACTGTACCCAGCTGACGTTGTGCTGATCGAAGGTATCCTGGTCTTCTACTTTCCCGAAGTGAGGGATCTCTTTCACATGAAACTGTTTGTTGATACTGATTCAGATACCAGACTTGCGAGACGAGTTCCGAGGGATATAATGGAACGTGGCCGAGACTTGGAGCAGGTGCTCAACCAGTATATGAACTTTGTGAAGCCAGCATTTGAAGAGTTCTGTCTTCCGACAAAAAAATTCGCTGACGTCATTATCCCGCGAGGAGCAGATAATTTAGTGGCTATCGATTTGATAGTACAACATATCTCAGACTATCTGAAGAAGAATCCCAGCGAGGTGCTTCTGACGGGCGGTAGCTCGATTTCTGATAGTCCACAGCGGAGCTCAAAAGGGGGTCGCCCGCATTAG

Protein

MSISAVLRNSRTRALCVLVVLRKSVRSFYTYKMAEKPADYLSTNGFESKTPFLIGVAGGTASGKSTVCQRIMEKLGQQHKEHTERRVVCISQDSFYRSLTAPERLRAERGQFNFDHPDAFDDKKLLATLKDILAGKKVEIPEYDYISNSISNRTNTLYPADVVLIEGILVFYFPEVRDLFHMKLFVDTDSDTRLARRVPRDIMERGRDLEQVLNQYMNFVKPAFEEFCLPTKKFADVIIPRGADNLVAIDLIVQHISDYLKKNPSEVLLTGGSSISDSPQRSSKGGRPH

Catalytic Activity

ATP + cytidine = ADP + CMP + H(+)
ATP + uridine = ADP + H(+) + UMP

Similarity

Belongs to the uridine kinase family.

Uniprot

H9JEI9   A0A2A4IUT5   A0A2W1BKM0   A0A3S2TU00   A0A194PW89   A0A2H1WCU2   + More
A0A212F8R1   K7IQ12   A0A2A3EFX2   E2AY76   A0A151IKL3   A0A195AVN2   F4W668   A0A026WDQ3   A0A0L7R5K0   A0A195DMR4   A0A158P1Z5   A0A0C9R3Q2   A0A088ACE9   A0A232F7H7   A0A195FJ68   E2BBQ7   A0A310SU56   A0A154PI08   A0A146M717   B0X2H1   A0A1Q3FHC7   A0A1Q3FI05   A0A146M112   A0A1B6GHH6   A0A1L8DLA6   A0A1Q3FFF7   A0A067RI37   A0A0M9AAM4   A0A1B6HFP3   A0A182G8Z8   A0A1B6J270   A0A182G3C9   A0A069DRG0   A0A0P4VRW3   T1I1T1   A0A023ELP2   Q16WT5   A0A0J7KNK9   U5EIT0   A0A2M3Z518   A0A182F9D2   A0A1B0DKQ4   A0A2M4AE85   A0A1J1IPB9   A0A139WM57   A0A182RCX4   A0A1J1ISK0   Q7PFQ6   A0A182X1P4   A0A182TW47   A0A182XX70   D6WCQ7   A0A1B6CPJ1   A0A182PA93   A0A182QBU9   A0A182JWR1   A0A0N1PIC4   A0A182N6Y5   A0A182IYP2   J3JTK3   A0A1Y1KGT7   E0VGZ7   A0A2S2N9K3   F5HJD6   A0A182I8L1   W5JLR9   J9K5X8   A0A2M4BXT5   A0A1Y1KEC7   C4WTJ8   A0A336L0R4   A0A1W4WSB9   A0A336MKH4   A0A182VQA6   A0A2M3Z5A6   A0A0P9BT75   A0A2M4AE99   A0A2H8TNP1   A0A1W4WTC2   A0A182MJN7   B3N1M8   A0A0Q9WLW1   A0A0K8TNU2   A0A3B0JM33   A0A1W4V5A8   A0A0R3NHT9   A0A0R1E729   B4LXM8   A0A1W4USZ1   B7Z0P8   A0A0Q9X912   Q297B7   A0A0L0CB21  

EC Number

2.7.1.48

Pubmed

19121390    28756777    26354079    22118469    20075255    20798317    + More
21719571    24508170    30249741    21347285    28648823    26823975    24845553    26483478    26334808    27129103    24945155    17510324    18362917    19820115    12364791    14747013    17210077    25244985    22516182    23537049    28004739    20566863    20920257    23761445    17994087    26369729    15632085    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26108605   

EMBL

BABH01003214    NWSH01006302    PCG63525.1    KZ150060    PZC74235.1    RSAL01000001    + More
RVE55189.1    KQ459596    KPI95400.1    ODYU01007812    SOQ50895.1    AGBW02009681    OWR50124.1    KZ288256    PBC30618.1    GL443762    EFN61611.1    KQ977199    KYN04995.1    KQ976731    KYM76298.1    GL887707    EGI70203.1    KK107293    QOIP01000005    EZA53144.1    RLU22242.1    KQ414654    KOC66036.1    KQ980724    KYN14121.1    ADTU01006918    GBYB01001456    JAG71223.1    NNAY01000723    OXU26791.1    KQ981523    KYN40453.1    GL447151    EFN86833.1    KQ760132    OAD61815.1    KQ434923    KZC11506.1    GDHC01004083    JAQ14546.1    DS232288    EDS39194.1    GFDL01008101    JAV26944.1    GFDL01007871    JAV27174.1    GDHC01006073    JAQ12556.1    GECZ01008016    JAS61753.1    GFDF01006835    JAV07249.1    GFDL01008757    JAV26288.1    KK852460    KDR23521.1    KQ435712    KOX79373.1    GECU01034159    JAS73547.1    JXUM01048681    JXUM01048682    JXUM01048683    JXUM01048684    JXUM01048685    KQ561572    KXJ78123.1    GECU01014444    JAS93262.1    JXUM01040832    JXUM01040833    JXUM01040834    KQ561261    KXJ79169.1    GBGD01002608    JAC86281.1    GDKW01001954    JAI54641.1    ACPB03005165    GAPW01003431    JAC10167.1    CH477554    EAT39076.1    LBMM01004956    KMQ91958.1    GANO01002508    JAB57363.1    GGFM01002861    MBW23612.1    AJVK01016093    GGFK01005701    MBW39022.1    CVRI01000057    CRL02085.1    KQ971317    KYB28983.1    CRL02086.1    AAAB01008844    EAA45221.4    EGK96397.1    EEZ97798.2    GEDC01021950    GEDC01003045    JAS15348.1    JAS34253.1    AXCN02000314    KQ459781    KPJ19966.1    APGK01053340    BT126560    KB741223    KB630676    AEE61524.1    ENN72363.1    ERL83774.1    GEZM01086072    GEZM01086069    JAV59798.1    DS235154    EEB12653.1    GGMR01001169    MBY13788.1    EGK96396.1    APCN01003084    ADMH02001170    ETN63845.1    ABLF02039332    GGFJ01008746    MBW57887.1    GEZM01086070    JAV59799.1    AK340648    BAH71218.1    UFQS01001431    UFQT01001431    SSX10855.1    SSX30535.1    UFQS01000685    UFQT01000685    SSX06194.1    SSX26548.1    GGFM01002942    MBW23693.1    CH902661    KPU74887.1    GGFK01005792    MBW39113.1    GFXV01003972    MBW15777.1    AXCM01003040    EDV33997.1    CH940650    KRF82935.1    GDAI01001790    JAI15813.1    OUUW01000007    SPP83295.1    CM000070    KRT00625.1    CM000160    KRK04574.1    EDW66812.1    AE014297    ACL83561.1    CH933806    KRG01636.1    EAL28289.4    JRES01000664    KNC29446.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000007151    UP000002358    + More
UP000242457    UP000000311    UP000078542    UP000078540    UP000007755    UP000053097    UP000279307    UP000053825    UP000078492    UP000005205    UP000005203    UP000215335    UP000078541    UP000008237    UP000076502    UP000002320    UP000027135    UP000053105    UP000069940    UP000249989    UP000015103    UP000008820    UP000036403    UP000069272    UP000092462    UP000183832    UP000007266    UP000075900    UP000007062    UP000076407    UP000075902    UP000076408    UP000075885    UP000075886    UP000075881    UP000053240    UP000075884    UP000075880    UP000019118    UP000030742    UP000009046    UP000075840    UP000000673    UP000007819    UP000192223    UP000075920    UP000007801    UP000075883    UP000008792    UP000268350    UP000192221    UP000001819    UP000002282    UP000000803    UP000009192    UP000037069   

PRIDE

H9JEI9   

Pfam

PF00485   PRK        + More
PF01259   SAICAR_synt
PF00731   AIRC

Interpro

IPR000764   Uridine_kinase-like        + More
IPR006083   PRK/URK       
IPR029925   UCK-2       
IPR027417   P-loop_NTPase       
IPR028923   SAICAR_synt/ADE2_N       
IPR000031   PurE_dom       
IPR035893   PurE_sf       
IPR033626   PurE_classII       
IPR018236   SAICAR_synthetase_CS       
IPR029920   UCK-1       

SUPFAM

SSF52540   SSF52540        + More
SSF52255   SSF52255       

Gene 3D

3.40.50.7700    

CDD

cd02023  UMPK

ProteinModelPortal

H9JEI9   A0A2A4IUT5   A0A2W1BKM0   A0A3S2TU00   A0A194PW89   A0A2H1WCU2   + More
A0A212F8R1   K7IQ12   A0A2A3EFX2   E2AY76   A0A151IKL3   A0A195AVN2   F4W668   A0A026WDQ3   A0A0L7R5K0   A0A195DMR4   A0A158P1Z5   A0A0C9R3Q2   A0A088ACE9   A0A232F7H7   A0A195FJ68   E2BBQ7   A0A310SU56   A0A154PI08   A0A146M717   B0X2H1   A0A1Q3FHC7   A0A1Q3FI05   A0A146M112   A0A1B6GHH6   A0A1L8DLA6   A0A1Q3FFF7   A0A067RI37   A0A0M9AAM4   A0A1B6HFP3   A0A182G8Z8   A0A1B6J270   A0A182G3C9   A0A069DRG0   A0A0P4VRW3   T1I1T1   A0A023ELP2   Q16WT5   A0A0J7KNK9   U5EIT0   A0A2M3Z518   A0A182F9D2   A0A1B0DKQ4   A0A2M4AE85   A0A1J1IPB9   A0A139WM57   A0A182RCX4   A0A1J1ISK0   Q7PFQ6   A0A182X1P4   A0A182TW47   A0A182XX70   D6WCQ7   A0A1B6CPJ1   A0A182PA93   A0A182QBU9   A0A182JWR1   A0A0N1PIC4   A0A182N6Y5   A0A182IYP2   J3JTK3   A0A1Y1KGT7   E0VGZ7   A0A2S2N9K3   F5HJD6   A0A182I8L1   W5JLR9   J9K5X8   A0A2M4BXT5   A0A1Y1KEC7   C4WTJ8   A0A336L0R4   A0A1W4WSB9   A0A336MKH4   A0A182VQA6   A0A2M3Z5A6   A0A0P9BT75   A0A2M4AE99   A0A2H8TNP1   A0A1W4WTC2   A0A182MJN7   B3N1M8   A0A0Q9WLW1   A0A0K8TNU2   A0A3B0JM33   A0A1W4V5A8   A0A0R3NHT9   A0A0R1E729   B4LXM8   A0A1W4USZ1   B7Z0P8   A0A0Q9X912   Q297B7   A0A0L0CB21  

PDB

1XRJ     E-value=8.7524e-86,     Score=806

KEGG

692983    K00876 uridine kinase [EC:2.7.1.48] | (RefSeq) uridine-cytidine kinase 2

PATHWAY

00240    Pyrimidine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0044206   GO:0019206   GO:0005524   GO:0006238   GO:0004639   GO:0006189   GO:0016301   GO:0005829   GO:0004849   GO:0044211   GO:0016021   GO:0008152   GO:0005622   GO:0005840   GO:0005737   GO:0006426   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR10285:SF147   PTHR10285:SF66  

Length:

289

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.546939999999999

Exp number, first 60 AAs:

0.01587

Total prob of N-in:

0.05208

outside

1  -  289

 

 

Pi

25.422199

Theta

20.978991

Tajima's D

1.062884

CLR

0.529873

CSRT

0.688115594220289

Interpretation

Uncertain