Gene

KWMTBOMO08663  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007942

Annotation

PREDICTED:_casein_kinase_2_beta_subunit_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(-):1747742-1759726      View in EpiBrowser

Full name

Casein kinase II subunit beta      

Alternative Name

Phosvitin

Location in the cell

Nuclear   Reliability : 3.473

CDS

ATGAGCAGCTCCGAGGAGGTATCCTGGATCGCTTGGTTTTGCACGCTTCGAGGCAATGAGTTTTTCTGTGAGGTTGACGAAGACTACATAAATGATAAATTTAATCTAACCGGCTTAAATGAGCAAGTTCCACATTATAGAGAGGCGCTGGACATGATTCTGGATCTGGAGCCAGATGATGACATTGAAGACAATCCAAATGAATCTGATCTGGTGGAACAAGCATCGGAGATACTATATGGATTGATACATGCCCGGTACATATTGACCAATAGGGGCATTAGTCAAATGTTGGATAAGTTCCAGTCTGGGGATTTTGGATATTGCCCACGTGTATACTGTGAATGCCAACCTATGCTGCCAATTGGTTTGTCGGACGTCCCCGCCGAAGCGATGGTGAAGCTGTACTGCCCGCGCTGCATGGACGTGTACACGCCCAAATCCTCGCGCCACCACCACACCGACGGCGCTTACTTCGGCACCGGCTTCCCGCACATGGTGTTCATGGTGCACCCCGATAAACGACCAAAACGACCTGCCTCTCAATTCGTACCAAGACTATACGGGTTCAAGATTCACCCGCTCGCCTACCAAATCCAGCAGGCGGCTGCGAACTCCAAGCCGCCGCAGCGCAGCCTGTCGTACAACAACGAAACGAAGACATCAAGTAACATTCCAAAATGA

Protein

MSSSEEVSWIAWFCTLRGNEFFCEVDEDYINDKFNLTGLNEQVPHYREALDMILDLEPDDDIEDNPNESDLVEQASEILYGLIHARYILTNRGISQMLDKFQSGDFGYCPRVYCECQPMLPIGLSDVPAEAMVKLYCPRCMDVYTPKSSRHHHTDGAYFGTGFPHMVFMVHPDKRPKRPASQFVPRLYGFKIHPLAYQIQQAAANSKPPQRSLSYNNETKTSSNIPK

Description

Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity).

Subunit

Tetramer of two alpha and two beta subunits.
Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions (By similarity).

Similarity

Belongs to the casein kinase 2 subunit beta family.

Keywords

Phosphoprotein   Wnt signaling pathway   3D-structure   Metal-binding   Zinc  

Feature

chain  Casein kinase II subunit beta

Uniprot

Q59HV8   A0A2A4K652   A0A437BXK2   A0A1E1W5R4   B0LBZ2   A0A212F8R4   + More
A0A1B0YZ24   O76485   A0A222AJD6   A0A1Y1JQX8   A0A3L8DP61   A0A2A4K6V1   A0A1W4XIR6   V5G8U2   A0A222AJ03   E2AY73   D6WC45   A0A026WB39   A0A158P1Z7   A0A2A3EGK7   A0A088ACC2   A0A1U7SEA6   F4W671   A0A195AW85   A0A195FIF4   A0A158P1Z8   A0A2K5BXM4   G1LRR8   K7GQK6   G1PDM4   G3VEQ6   L8I133   W5P9Z9   G3SR02   F6UJ03   A0A3Q0EFP5   A0A2U3WZY5   A0A2K6FMD0   L9KH77   A0A2U3Y4J6   S9X428   A0A2K5J9P1   A0A2K6BQJ1   A0A2K6LUQ7   G3QS09   A0A2R8ZRI0   A0A096N6T3   A0A2K6RNP1   A0A2K5ND92   H2QSN4   G7P4Q2   A0A2K6A724   G7MRJ2   Q5SRQ6   A0A2K6UH16   M3W831   F6T6M8   A0A151NR38   K9IR06   D2I4A3   F7BB79   F7I307   Q28EV4   N0E4C0   A0A1L8F8J5   Q6DEU1   P28021   E4Z7F8   U3FXB6   A0A1W7RIF2   J3SBX9   A0A452HIA2   A0A0K8S1S6   A0A1S3GFQ8   A0A287CSF0   A0A1U7R3N7   A0A250YCD5   A0A286XQ20   Q68G11   G3HZG2   A0A2K6BQC5   A0A2K6LUP2   A0A384DSZ0   L5L690   A0A2K5UQB7   A0A2I2Y5K6   A0A341AY35   A0A0D9R896   A0A452EHL5   A0A2Y9ECH0   A0A2U3UYY9   A0A3Q7NCK0   A0A340XDT6   A0A2R8ZW67   A0A2K6RNQ0   A0A2Y9HSK6   A0A2I2ULM1   A0A2U3Y483   A0A2K5NCS1   L5LBI0  

Pubmed

18184036    18183285    22118469    27341138    28004739    30249741    + More
20798317    18362917    19820115    24508170    21347285    21719571    20010809    21993624    21709235    22751099    20809919    19892987    23385571    23149746    22722832    25362486    16136131    22002653    17431167    11181995    14574404    17081983    18691976    18669648    19369195    19608861    20068231    21269460    21406692    23186163    24275569    25755297    25944712    17975172    17495919    22293439    23521802    27762356    1544409    15388915    23915248    26358130    23025625    28562605    25727380    28087693    15489334    15632090    22673903    21804562    23929341    29704459    23258410   

EMBL

AB206395    BAD91394.1    NWSH01000087    PCG79745.1    RSAL01000001    RVE55196.1    + More
GDQN01008732    JAT82322.1    EF554578    ABU49713.1    AGBW02009681    OWR50132.1    KX014741    ANO53990.1    AF071211    KY609757    ASO76480.1    GEZM01103029    GEZM01103027    GEZM01103025    JAV51599.1    QOIP01000005    RLU22230.1    PCG79746.1    GALX01001921    JAB66545.1    KY563904    ASO76365.1    GL443762    EFN61608.1    KQ971316    EEZ97852.2    KK107293    EZA53148.1    ADTU01006918    KZ288256    PBC30614.1    GL887707    EGI70206.1    KQ976731    KYM76295.1    KQ981523    KYN40450.1    ACTA01043589    AEMK02000053    AAPE02050101    AEFK01182226    AEFK01182227    JH882244    ELR50200.1    AMGL01059048    KB320852    ELW61854.1    KB016672    EPY85377.1    CABD030044187    AJFE02111636    AHZZ02024399    AHZZ02024400    AACZ04022799    AQIA01052296    CM001279    EHH52918.1    JSUE03030630    CM001256    EHH18165.1    AL662899    AL670886    AL805934    BX511262    CR354443    CR753842    CR759761    CH471081    EAX03475.1    AANG04003556    AKHW03002316    KYO39311.1    GABZ01002605    JAA50920.1    GL194442    EFB18166.1    CR762325    CAJ83806.1    HE864436    CCI79673.1    CM004481    CM004480    OCT66208.1    OCT67904.1    BC077003    CR848278    AAH77003.1    CAJ82633.1    X62376    BC077212    FN677520    CBK38916.1    GAEP01000290    JAB54531.1    GDAY02000489    JAV50924.1    JU174094    AFJ49620.1    GBKC01000606    GBKD01000391    JAG47227.1    AGTP01099976    GFFW01003487    JAV41301.1    AAKN02021590    BC078807    HE864426    HE864432    HE864433    HE864434    CH474121    AAH78807.2    CCI79663.1    CCI79669.1    EDL83521.1    JH000969    KE665405    RAZU01000018    EGV95287.1    ERE88833.1    RLQ79007.1    KB030277    ELK18925.1    AC244030    LWLT01000028    KB113694    ELK23380.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000279307    UP000192223    UP000000311    + More
UP000007266    UP000053097    UP000005205    UP000242457    UP000005203    UP000189705    UP000007755    UP000078540    UP000078541    UP000233020    UP000008912    UP000008227    UP000001074    UP000007648    UP000002356    UP000007646    UP000002281    UP000189704    UP000245340    UP000233160    UP000011518    UP000245341    UP000233080    UP000233120    UP000233180    UP000001519    UP000240080    UP000028761    UP000233200    UP000233060    UP000002277    UP000009130    UP000233100    UP000233140    UP000006718    UP000005640    UP000233220    UP000011712    UP000002280    UP000050525    UP000008225    UP000186698    UP000291020    UP000081671    UP000005215    UP000189706    UP000005447    UP000001075    UP000030759    UP000273346    UP000261680    UP000010552    UP000252040    UP000029965    UP000291000    UP000248480    UP000245320    UP000286641    UP000265300    UP000248481   

PRIDE

Q59HV8    O76485    K7GQK6    Q5SRQ6    P28021    G3HZG2    + More

Pfam

PF01214   CK_II_beta

Interpro

IPR035991   Casein_kinase_II_beta-like        + More
IPR000704   Casein_kinase_II_reg-sub       
IPR016149   Casein_kin_II_reg-sub_N       

SUPFAM

SSF57798   SSF57798       

Gene 3D

1.10.1820.10    

ProteinModelPortal

Q59HV8   A0A2A4K652   A0A437BXK2   A0A1E1W5R4   B0LBZ2   A0A212F8R4   + More
A0A1B0YZ24   O76485   A0A222AJD6   A0A1Y1JQX8   A0A3L8DP61   A0A2A4K6V1   A0A1W4XIR6   V5G8U2   A0A222AJ03   E2AY73   D6WC45   A0A026WB39   A0A158P1Z7   A0A2A3EGK7   A0A088ACC2   A0A1U7SEA6   F4W671   A0A195AW85   A0A195FIF4   A0A158P1Z8   A0A2K5BXM4   G1LRR8   K7GQK6   G1PDM4   G3VEQ6   L8I133   W5P9Z9   G3SR02   F6UJ03   A0A3Q0EFP5   A0A2U3WZY5   A0A2K6FMD0   L9KH77   A0A2U3Y4J6   S9X428   A0A2K5J9P1   A0A2K6BQJ1   A0A2K6LUQ7   G3QS09   A0A2R8ZRI0   A0A096N6T3   A0A2K6RNP1   A0A2K5ND92   H2QSN4   G7P4Q2   A0A2K6A724   G7MRJ2   Q5SRQ6   A0A2K6UH16   M3W831   F6T6M8   A0A151NR38   K9IR06   D2I4A3   F7BB79   F7I307   Q28EV4   N0E4C0   A0A1L8F8J5   Q6DEU1   P28021   E4Z7F8   U3FXB6   A0A1W7RIF2   J3SBX9   A0A452HIA2   A0A0K8S1S6   A0A1S3GFQ8   A0A287CSF0   A0A1U7R3N7   A0A250YCD5   A0A286XQ20   Q68G11   G3HZG2   A0A2K6BQC5   A0A2K6LUP2   A0A384DSZ0   L5L690   A0A2K5UQB7   A0A2I2Y5K6   A0A341AY35   A0A0D9R896   A0A452EHL5   A0A2Y9ECH0   A0A2U3UYY9   A0A3Q7NCK0   A0A340XDT6   A0A2R8ZW67   A0A2K6RNQ0   A0A2Y9HSK6   A0A2I2ULM1   A0A2U3Y483   A0A2K5NCS1   L5LBI0  

PDB

4MD9     E-value=1.4223e-100,     Score=932

KEGG

692538    K03115 casein kinase II subunit beta | (RefSeq) Ck2b, BmCK2b; casein kinase 2 beta subunit

PATHWAY

03008    Ribosome biogenesis in eukaryotes - Bombyx mori (domestic silkworm)
04137    Mitophagy - animal - Bombyx mori (domestic silkworm)
04310    Wnt signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0005956   GO:0016301   GO:0019887   GO:0016055   GO:0006468   GO:0005737   GO:0043537   GO:0004674   GO:0042802   GO:0003682   GO:0005886   GO:0032927   GO:0008134   GO:0005102   GO:0031519   GO:0018107   GO:0019904   GO:0033211   GO:0061154   GO:0010862   GO:0046872   GO:0006418   GO:0000166   GO:0004820   GO:0006426   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR11740  

Length:

227

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00904

Exp number, first 60 AAs:

0.00034

Total prob of N-in:

0.03805

outside

1  -  227

 

 

Pi

36.659356

Theta

199.426636

Tajima's D

-0.888414

CLR

23100.596848

CSRT

0.15859207039648

Interpretation

Uncertain