Gene

KWMTBOMO08651

Pre Gene Modal

BGIBMGA007946

Annotation

PREDICTED:_homeobox_protein_extradenticle_isoform_X3_[Amyelois_transitella]

Location

Bomo_Chr15(-):1628673-1643922      View in EpiBrowser

Full name

Homeobox protein extradenticle      

Transcription factor

Homeobox

Location in the cell

Nuclear   Reliability : 4.451

CDS

ATGGACGATCCGAACCGGATGATGGCGCATAGCGGCGGAATGATGGGACCGCAGGGTTATGGGCTGCCTGGAGGAGAAGGCGCACCAGCCTCTGAAGGAGGCGAAGCTCGCAAGCAGGACATTGGCGAAATTTTACAACAAATAATGAACATTACAGATCAAAGCTTAGATGAAGCGCAGGCGAGAAAACACACGCTGAACTGCCATAGAATGAAGCCTGCTCTGTTTTCAGTACTCTGTGAAATTAAAGAAAAGACAGTGCTATCTCTGAGAAACACTCAAGAGGAGGAGCCACCTGATCCCCAGCTGATGAGGCTTGACAATATGTTGATTGCGGAGGGTGTAGCTGGACCAGAGAAAGGTGGAGGTGCTGGTGCTGCCGCCTCGGCATCTGCTGCGGCCGGTGAATGGGATAATGCCATCGAGCACTCGGACTACCGTGCAAAACTGGCGCAGATACGGCAGATCTATCATCAGGAGCTCGACAAGTACGAGAATGCCTGCAATGAGTTCACTACACACGTCATGAATTTGCTAAGAGAGCAAAGTCGCACCAGACCTATCACCCCTAAGGAAATTGAACGCATGGTGCAAATAATTCACAAGAAGTTTAGCTCCATCCAGATGCAGCTCAAGCAGTCCACTTGCGAGGCAGTGATGATTCTGCGCTCACGTTTCCTGGACGCGCGCAGAAAGCGCCGTAACTTCAGCAAGCAAGCGTCGGAGATCCTCAATGAATACTTCTACTCGCATCTGTCGAACCCGTACCCCAGCGAGGAGGCGAAAGAGGAGCTGGCGCGCAAGTGCGGCATTACCGTATCGCAGGTCTCTAATTGGTTTGGCAACAAGCGCATTCGCTACAAGAAGAACATTGGCAAGGCGCAAGAGGAGGCCAACCTTTATGCTGCCAAGAAAGCAGCCGCGGGCGCGTCGCCGTACTCGCTGGGCGGAGCCTCGGGCGCGGCCACTCCGCTGATGTCGCCGGCGCCGCCCCAGGACTCGCTGGGCTACTCGCTGCCGGCGCCGCCCTACGACCAGCAGCCGCCCTACGACGCCTCCATGCCCTACGACCCCATGCACCAGGATCTATCGCCCTAA

Protein

MDDPNRMMAHSGGMMGPQGYGLPGGEGAPASEGGEARKQDIGEILQQIMNITDQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSLRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGAGAAASASAAAGEWDNAIEHSDYRAKLAQIRQIYHQELDKYENACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAAGASPYSLGGASGAATPLMSPAPPQDSLGYSLPAPPYDQQPPYDASMPYDPMHQDLSP

Description

Transcription factor which acts with the selector homeodomain proteins altering the regulation of downstream target genes such as wingless (wg), teashirt (tsh) and decapentaplegic (dpp), thus affecting segmental identity.
Transcription factor which acts with the selector homeodomain proteins altering the regulation of downstream target genes such as wingless (wg), teashirt (tsh) and decapentaplegic (dpp), thus affecting segmental identity. Delimits the eye field and prevent inappropriate eye development. Required for proper localization of chordotonal organs within the peripheral nervous system (By similarity).
Transcription factor which acts with the selector homeodomain proteins altering the regulation of downstream target genes such as wingless (wg), teashirt (tsh) and decapentaplegic (dpp), thus affecting segmental identity. Delimits the eye field and prevent inappropriate eye development. Required for proper localization of chordotonal organs within the peripheral nervous system.

Subunit

Interacts with Ubx and hth.

Similarity

Belongs to the TALE/PBX homeobox family.

Keywords

Complete proteome   Developmental protein   DNA-binding   Homeobox   Nucleus   Reference proteome   Transcription   Transcription regulation   3D-structure  

Feature

chain  Homeobox protein extradenticle

Uniprot

A0A437BXL6   A0A212F8S4   A0A0N1PHL6   A0A194PPZ0   A0A1Q3G3Y4   A0A1E1WNI0   + More
A0A084W198   A0A0P6ITB1   A0A2M3Z586   Q7PMT1   A0A2M4CUF3   A0A2M4A3D6   A0A2M4BS67   T1PKG0   B4PXA8   A0A3B0KDQ8   A0A1I8PIR1   Q29CT2   B3MPX5   B4MT87   B4R5K9   B4IMG8   B3NXG0   A0A1W4VFS7   M9PHV1   P40427   D3TLK4   W8BW42   A0A0A1XE93   A0A034VEQ9   W8CAV1   A0A146KWX5   A0A146M850   A0A0M4ESN1   B4JX43   B4MA61   A0A0A9Z452   B4MAH8   S4PFR4   A0A0A9YZR8   B4L6Y9   W6JIB4   T1DQW0   A0A0P4W4B2   Q70WC6   A0A2L2Y7F7   Q70WC7   A0A1S3J440   A0A3Q3K1M7   A0A1S3J4J6   A0A1S3J493   A0A1S3J5T9   A0A1S3J488   V9KYP5   A0A3Q1JBP0   G3NIP3   A0A1U7R467   A0A3Q1I575   A0A2A4K735   A0A3B4CED3   A0A1L8F1R5   L8IS61   A0A3M6UXL0   A0A3B4DAS2   A0A3Q3IJ91   A0A3P8PST7   A0A3P9BQX5   A0A2D0R0M3   A0A3Q2Y3E9   A0A3B4XKA2   A0A3B4GQ75   A0A3Q1FBD8   A0A3B5AG53   A0A3Q3C417   A0A3Q3LFU2   A0A3Q4MHC6   A0A3Q1C4S4   A0A3Q0T4J9   A0A3P8SPZ2   A0A287D513   A0A3B1KEU1   A0A0Q3TJK0   A0A2K6UE69   A0A218V5J1   A0A2D0R314   I3JXW6   H2MDI0   A0A3P9K0L1   K7G9R2   A0A3Q1K971   Q5ZLI3   A0A2D0R0Y2   A0A3Q4AEL2   A0A2D0R308   A0A3P8YU20   A0A341CWW8   A0A2Y9T050   A0A2Y9DJA3   A0A3Q3NAS8   M3YR14  

Pubmed

22118469    26354079    24438588    26999592    12364791    17994087    + More
17550304    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    8104703    12537569    8100142    7914871    9346235    9463350    9450936    10067897    20353571    24495485    25830018    25348373    26823975    18057021    25401762    23622113    24333180    14623236    26561354    24402279    27762356    22751099    30382153    25186727    25329095    17554307    17381049    15592404    15642098    25069045   

EMBL

RSAL01000001    RVE55207.1    AGBW02009681    OWR50142.1    KQ459781    KPJ19987.1    + More
KQ459596    KPI95382.1    GFDL01000535    JAV34510.1    GDQN01002494    JAT88560.1    ATLV01019249    KE525266    KFB43992.1    GDUN01000960    JAN94959.1    GGFM01002914    MBW23665.1    AAAB01008968    EAA13242.3    GGFL01004290    MBW68468.1    GGFK01001944    MBW35265.1    GGFJ01006692    MBW55833.1    KA649189    AFP63818.1    CM000162    EDX01871.1    OUUW01000011    SPP86420.1    CH475411    EAL29404.1    CH902621    EDV44737.1    CH963851    EDW75326.1    CM000366    EDX18054.1    CH480996    EDW46313.1    CH954180    EDV46919.1    AE014298    AGB95434.1    AGB95435.1    U33747    L19295    AY061065    Z18864    EZ422306    ADD18582.1    GAMC01005393    GAMC01005392    JAC01164.1    GBXI01004553    JAD09739.1    GAKP01018899    GAKP01018898    GAKP01018897    JAC40053.1    GAMC01005391    JAC01165.1    GDHC01019359    JAP99269.1    GDHC01003030    JAQ15599.1    CP012528    ALC49352.1    CH916376    EDV95319.1    CH940655    EDW66120.1    KRF82573.1    GBHO01041461    GBHO01007025    GBHO01007024    GBHO01007020    JAG02143.1    JAG36579.1    JAG36580.1    JAG36584.1    EDW66237.1    GAIX01006455    JAA86105.1    GBHO01041466    GBHO01041464    GBHO01007030    GBHO01007021    JAG02138.1    JAG02140.1    JAG36574.1    JAG36583.1    CH933812    EDW06135.1    KRG07160.1    AB841084    BAO48187.1    GAMD01002229    JAA99361.1    GDRN01073255    JAI63426.1    AJ518944    CAD57738.1    IAAA01013580    IAAA01013581    LAA04083.1    AJ518943    CAD57737.1    JW871435    AFP03953.1    NWSH01000087    PCG79724.1    CM004481    OCT65556.1    JH880862    ELR58289.1    RCHS01000537    RMX58337.1    AGTP01020000    LMAW01002507    KQK80782.1    MUZQ01000043    OWK61327.1    AERX01013670    AERX01013671    AGCU01045094    AGCU01045095    AGCU01045096    AGCU01045097    AGCU01045098    AGCU01045099    AGCU01045100    AGCU01045101    AGCU01045102    AGCU01045103    AADN05000150    AJ719751    CAG31410.1    AEYP01042720    AEYP01042721    AEYP01042722    AEYP01042723    AEYP01042724    AEYP01042725    AEYP01042726    AEYP01042727    AEYP01042728   

Proteomes

UP000283053    UP000007151    UP000053240    UP000053268    UP000030765    UP000007062    + More
UP000002282    UP000268350    UP000095300    UP000001819    UP000007801    UP000007798    UP000000304    UP000001292    UP000008711    UP000192221    UP000000803    UP000092553    UP000001070    UP000008792    UP000009192    UP000085678    UP000261600    UP000265040    UP000007635    UP000189705    UP000218220    UP000261440    UP000186698    UP000275408    UP000265100    UP000265160    UP000221080    UP000264820    UP000261360    UP000261460    UP000257200    UP000261400    UP000264840    UP000261640    UP000261580    UP000257160    UP000261340    UP000265080    UP000005215    UP000018467    UP000051836    UP000233220    UP000197619    UP000005207    UP000001038    UP000265180    UP000265200    UP000007267    UP000000539    UP000261620    UP000265140    UP000252040    UP000248484    UP000248480    UP000261660    UP000000715   

PRIDE

M9PHV1    P40427    W6JIB4   

Pfam

PF03792   PBC        + More
PF00046   Homeodomain

Interpro

IPR001356   Homeobox_dom        + More
IPR017970   Homeobox_CS       
IPR005542   PBX       
IPR009057   Homeobox-like_sf       

SUPFAM

SSF46689   SSF46689       

CDD

cd00086  homeodomain

ProteinModelPortal

A0A437BXL6   A0A212F8S4   A0A0N1PHL6   A0A194PPZ0   A0A1Q3G3Y4   A0A1E1WNI0   + More
A0A084W198   A0A0P6ITB1   A0A2M3Z586   Q7PMT1   A0A2M4CUF3   A0A2M4A3D6   A0A2M4BS67   T1PKG0   B4PXA8   A0A3B0KDQ8   A0A1I8PIR1   Q29CT2   B3MPX5   B4MT87   B4R5K9   B4IMG8   B3NXG0   A0A1W4VFS7   M9PHV1   P40427   D3TLK4   W8BW42   A0A0A1XE93   A0A034VEQ9   W8CAV1   A0A146KWX5   A0A146M850   A0A0M4ESN1   B4JX43   B4MA61   A0A0A9Z452   B4MAH8   S4PFR4   A0A0A9YZR8   B4L6Y9   W6JIB4   T1DQW0   A0A0P4W4B2   Q70WC6   A0A2L2Y7F7   Q70WC7   A0A1S3J440   A0A3Q3K1M7   A0A1S3J4J6   A0A1S3J493   A0A1S3J5T9   A0A1S3J488   V9KYP5   A0A3Q1JBP0   G3NIP3   A0A1U7R467   A0A3Q1I575   A0A2A4K735   A0A3B4CED3   A0A1L8F1R5   L8IS61   A0A3M6UXL0   A0A3B4DAS2   A0A3Q3IJ91   A0A3P8PST7   A0A3P9BQX5   A0A2D0R0M3   A0A3Q2Y3E9   A0A3B4XKA2   A0A3B4GQ75   A0A3Q1FBD8   A0A3B5AG53   A0A3Q3C417   A0A3Q3LFU2   A0A3Q4MHC6   A0A3Q1C4S4   A0A3Q0T4J9   A0A3P8SPZ2   A0A287D513   A0A3B1KEU1   A0A0Q3TJK0   A0A2K6UE69   A0A218V5J1   A0A2D0R314   I3JXW6   H2MDI0   A0A3P9K0L1   K7G9R2   A0A3Q1K971   Q5ZLI3   A0A2D0R0Y2   A0A3Q4AEL2   A0A2D0R308   A0A3P8YU20   A0A341CWW8   A0A2Y9T050   A0A2Y9DJA3   A0A3Q3NAS8   M3YR14  

PDB

5ZJT     E-value=3.37265e-34,     Score=362

KEGG

692478    K09355 pre-B-cell leukemia transcription factor 1 | (RefSeq) Exd, PBX; homeobox protein extradenticl

GO

GO:0005634   GO:0043565   GO:0003700   GO:0005667   GO:0006357   GO:0007422   GO:0001654   GO:0003677   GO:0007438   GO:0032993   GO:0003713   GO:0000981   GO:0001158   GO:0042659   GO:0090575   GO:0045944   GO:0046982   GO:0005737   GO:0007525   GO:0007420   GO:0033613   GO:0035326   GO:0045893   GO:0003712   GO:0007432   GO:0008134   GO:0007585   GO:0021516   GO:0048666   GO:0008344   GO:0002087   GO:0001228   GO:0000980   GO:0006355   GO:0016620   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

Subcellular location

Nucleus  

Length:

365

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01119

Exp number, first 60 AAs:

0.00039

Total prob of N-in:

0.02281

outside

1  -  365

 

 

Pi

19.443541

Theta

19.358598

Tajima's D

-1.194183

CLR

1507.766481

CSRT

0.102894855257237

Interpretation

Uncertain