Gene

KWMTBOMO08648  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007948

Annotation

PREDICTED:_spectrin_alpha_chain_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(-):1561077-1596812      View in EpiBrowser

Full name

Spectrin alpha chain      

Location in the cell

Cytoplasmic   Reliability : 1.878 Nuclear   Reliability : 1.239

CDS

ATGGAGCAGATCCCACCACCGAAAGAGGTGAAGATCCTCGAAACAGCAGAGGACATTCAGGAGCGTCGTGAGGAGGTTTTGAACCGCTATGAAGAGTTTAAGCAGGAAGCCCGTGCCAAACGTGAGAAACTCGAGGACTCCCGTCGCTTCCAGTACTTCAAGCGTGATGCTGATGAACTCGAGTCGTGGATTCAGGAGAAGCTTCAGGCCGCCAGCGATGAGAGCTACAAAGATCCCACCAACCTTCAGGCGAAAATCCAGAAACATCAAGCATTCGAAGCGGAGGTAGCTGCGCACTCCAATGCTATTGTAGTTTTGGACAACACCGGGTCAGAGATGATAGCTGCGGGACACTTCGCTTCGGAGACCATCCGTCGGCGCTTGGACGAACTACACCGTCTCTGGGAACTGTTGCTGTCCCGCCTCGCCGAGAAGGGCATGAAGCTGCAGCAGGCGCTTGTACTGGTGCAGTTTCTGAGGCACTGCGATGAAGTCATGTTCTGGATTCATGACAAGGAAACGTTTGTGTGCGCGGATGAGTTCGGTTCTGACCTGGAGCATGTTGAGGTGCTTCAGCGCAAGTTCGACGAGTTCCAGAAGGACATGGCCGCCCAGGAGTACCGGGTCACTGAAGTCAACCAGCTGGCCGAGAGACTCGTACTCGAAGGACACCCTGAAAGGGAAACCATCGTCAAGAGAAAAGACGAGTTGAACGAAGCCTGGCAGCGCCTGCGTCAAATGGCACTCATGCGTCAAGAACGTTTGTTCGGAGCCCACGAGATCCAGCGCTTCAATCGCGATGCCGACGAGACCATCGCCTGGATCTCGGAGAAGGATGCCGTGCTCGGATCCGACGACTACGGGCGCGACCTGGCTACCGTGCAGACGCTACAGCGCAAGCACGAAGGAGTAGAGCGCGATCTGGCCGCGTTAGAGGACAAGGTGTCGGTGCTGGAAGGAGAGGCCGTCCGCCTGGGGGCCATCCACGGCGCGCACGCCGACGCCATCAGCGCCAAGCGCGACGAGGCGCACGCGGCCTGGCAGCGCCTGGTGCAGCGCGCCGCGCACCGCCGGCAGCGCCTCGAGGCCGCGCTCGCGCTGCACCGCTTCCTGGCCGACTACCGCGACCTGCTCTCCTGGCTCGCAGACATGCGGGCGCTCATCGCCGCCGACGACCTCGCCAAGGACGTGCCCGGGGCCGAGGCTCTGCTCGAGAGGCACCAGGAGCACAAGGGCGAGATGGACGCGCGCGCGGACGTGATCGGCGCGTGTGCCGTGGCGGGGCAGGCGCTGGTGGCCAGCGAGCACCACGCGGCGGCCGACGTGTCCGCGGCGCTGCACACGCTGGAGCGGGAGGCCGCAGCGCTGCAGCAGCTGTGGGAGCAGCGCCGCGTGCTCTACCTGCAGTGCATGGACCTGCAACTCTTCTACCGCGACACTGAACAAGCCGACGCCTGGATGCACAAACAAGAGGCTTTCCTTGCGAACGAAGATGTAGGAGACTCTTTAGACTCCGTGGAAGCTTTGCTGAAGAAACACGAAGACTTTGAAAAGTCACTCGCCGCGCAAGAAGAGAAGATCAAGGCCCTAGACGAGTTCGCTACCAAACTTATTGAGGGCAACCATTACGCCGCCGACGATGTCGCACAAAGACGAGAGATGTTGTTGGAGCGTCGTGCGGCTTTACTAGAGAAGTCGAACCAGCGCCGCGCTCTCCTCGAAGACGCCTACAAGTATCAACAGTTCGAACGCGATTGTGATGAAACTAAAGGCTGGGTAAACGAGAAGCTGAAGTTCGCCACCGACGACTCGTACTTGGATCCGACCAACCTGAATGGCAAGGTGCAGAAACATCAGAACTTCGAACAGGAGCTGCAGGCCAACAAGCCTCGCGTCGACGAGATAACGGCCGTCGGCAAGCGTCTGCTTGAGCTCGAACATTTTGCTCAACCTCAAATATCGTCTCGCGTGGAAGAGCTGGGCGGAATATGGGAGCGACTGGTGCAGTCTTCGGAGCTGAAGGGAAACAAGTTGCAGGAAGCGGCTCAACAACAGCAGTACAATCGGGCCGTCGAGGACATTGAACTTTGGCTCTCGGAAGTTGAAGGACAGCTGCTCAGCGAGGACTACGGGAAGGATCTGACCAGCGTGCAGAATCTCCAGAAGAAGCACGCGCTGTTGGAGGCCGACGTGAGCTCGCACGCCGAACGCATCGACGCCATACGGAACCAGGCCGAGCAGTTCATAGAGAAGGGACACTTCGACGCGGATAACATCAAGGCTAAGCGGGACGCGTTGGTGGGCCGATACGCGGCTCTGGATGCGCCCATGGCGGTGCGCAAGCGGAGGCTGCTGGACTCGCTGCAGGCGCAGCAGCTGTTCCGCGACCTGGACGACGAGGCCGCCTGGATACGGGAGAAGGAGCCCGTAATTGCGTCCACGAACAGAGGTCGCGACCTGATCGGCGTCCAGAACCTTATGAAGAAGCACCAGGCCGTGCTGGGCGAGATGGCGCAGCACGAGGCGCGCGTGGAGGCGGTGCGGGCGGCCGGGGCTGCGCTGCGGGACGCCGGACACTTCGCCGCCGCCGACATCGCCGCCAGACTCACGCAGCTCCGCGACAACTGGACACAGCTGCAGGAGAAGGCGCTGCAGCGTAAACAAGACCTCGAAGACTCTCTTCAAGCTCAGCAGTACTTTGCTGATGCCAACGAAGCTGAATCTTGGATGAGAGAGAAGGAGCCCATCGCCTGCACCCAGGACTACGGAAAGGACGAGGACTCCTCTGAGGCGCTGCTAAAGAAACACGAGGCCTTGCTGTCTGACTTGGAAGCTTTCGGGAATACCATCAAGTCGCTGAGGGAACAGGCCAATTCATGCAGACAGCAGGAGTCGCCCGTGGTGGACGAGTCGGGCAAGGAGTGCGTGGCGGCGCTGTACGACTACGCGGAGAAGTCACCGCGCGAGGTCTCCATGAAGCGCGGCGACGTGCTCACGCTGCTCAACTCCAACAACAAGGACTGGTGGAAGGTGGAAGTAAACGACCGCCAAGGCTTCGTCCCGGCCGCATACGTCAAGAAGATCGACGCCGGACTGTCGTCCTCCCAGCAGAACCTCGCCGACTCCAACTCCATCGCCGCCAGACAGAATCAGATCGAGTCGCAGTATGACAACCTGCTGGGGCTGGCGCGCGAGCGGCAGAACAAACTCAACGAGACCGTCAAGGCCTACGTGCTGGTGCGGGAGGCGGCCGAGCTCGCCACCTGGATCAAGGACAAGGAGATGCACGCTCAAGTTCAAGACGTGGGCGAAGATCTGGAGCAGGTCGAGGTGATGCAGAAGAAGTTCGACGACTTCCAGAACGACCTGCGCGCCAACGAGGTGCGGCTCGCCGAGATGAACGAGATCGCCGTGCAGCTGATGACCGTCGGACAGACCGAGGCAGCCCTGAAGATCAAGACTCAGATGCAGGAGCTGAACTCGAAGTGGAGCTCGCTGCAGCAGCTGACGGCGGAGCGCGCGGCGCAGCTGGGCTCGGCGCACGAGGTGCAGCGCTTCCACCGCGACGTCGACGAGACCAAGGACTGGATCGCGGAGAAGGACGCCGCGCTCGCCTCCGACGACCTGGGCCGCGACCTGCGCTCCGTGCAGACCCTGCAGCGCAAGCATGAAGGCCTAGAGCGCGATTTAGCAGCCCTCGGCGACAAGATCCGCCAACTGGACGACACCGCCAACCGGCTGATGTCCACGCACGGGGACTCCGCCGACGCTACCTACAGCAAGCAGATAGAGATCAACGAAGCCTGGCAGCAACTGCAGGCGCGCGCCAATGCCAGGAAGGAGAAGCTTCTGGACTCCTACGACCTGCAGAGGTTCTTGTCGGACTACCGCGACTTGATGGCGTGGATCAACTCGATGATGGCGCTGGTGAGCTCGGACGAACTCGCCAATGACGTCACCGGCGCTGAGGCCCTGCTGGAAAGACATCAGGAGCACCGTACGGAGATGGACGCTCGCGCGGGCACGTTCCAGGCTCTGGAACTGTTCGGCCAGCAGCTGCTGCAGGGCGGCCACTACGCCAGCGTCGACATACAGGAGAAGCTCAACAACATGAGCGACGCCAGACAGGAACTCGAGAAAGCTTGGGTGAACCGACGCATGAAGTTAGACCAGAACTTGGAGCTGCAGCTGTTCTACCGTGACTGCGAGCAGGCGGAGGGCTGGATGGCCGCTCGCGAGGCCTTCCTGGCGCCCGCGGACCACGCCGACTCCGCCGACCAGCAGCAGCCGGACAACGTCGAGCAACTCATCAAGAAACACGAAGACTTCGACAAGGCCATCAATGCTCACGAGGAGAAGATTGCCCAGCTGCAGACGTTGGCCGACCAGCTGATCGCTTCCGACCACTACGCGACCGACGACATCGACGACAAGCGCAAGCAGGTGCTCGACCGCTGGAGGCACCTCAAGGAGGCACTCATAGAGAAACGCTCCAGATTGGGTGATGAACAAACTCTGCAACAATTCTCTCGCGACGCTGACGAGATGGAGAATTGGATCATGGAGAAGATGCAGTTAGCTACTGAAGAGAGTTACAAGGACCCAACCAATATTCAGTCCAAACATCAGAAGCACCAGGCGTTCGAAGCAGAACTGGCGGCCAACGCCGAGCGCATCCAGTCCGTGCTCGCCATGGGAGGCAACCTCGTGCAGCGCGGACAGTGCAGCGGCAGCGAGGATGCCGTGCAGGCTCGTCTCGCTTCCATCGCTGACCAATGGGAGTACCTCACTCAGAAGACTACAGAGAAGTCTCTGAAATTGAAAGAAGCGAACAAGCAGCGGACTTACATTGCTGCCGTTAAAGATCTGGACTTCTGGCTCGGTGAGGTCGAGAGCTTGTTGACCTCAGAAGACTCCGGCAAGGACCTGGCTTCTGTTCAGAACTTAATGAAGAAACACCAGCTCGTGGAAGCTGATATCCAAGCTCACGAGGACAGAATCAATGACATGAACGGGCAGGCGGACGCGCTGGTGGAGAGCGGGCAGTTCGACAGCGCCGGCATCGGCTCGCGCCGCGACGCCATCAACGAGCGCTTCGAGCGCGTGCGCAACCTCGCCGCGCACCGCCGCGCCAGACTGCACGAGGCCAACACGCTGCACCAGTTCTTCAGGGACATCGCCGACGAGGAGTCCTGGATCAAGGAGAAAAAACTTTTGGTCGCTTCGGATGACTACGGCCGCGACTTGACCGGCGTCCAGAACTTACTGAAGAAGCACAAGCGTCTCGAAGCGGAACTTGCGAGTCACGAGCCCGCCATACAAGCCGTGCAGGAGGCCGGCGAGAAGCTGATGGACGTGTCCAACCTTGGCGTGCTCGAGATCGAACAGCGGCTGAAAGCTCTGGCCTTGGCCTGGGATGAACTCCAAGCGCTGGCTGCCGAGCGAGGGGCCAAGCTGCAGCAGTCGCTCGCCTACCAACAGTTCCTTGCCAAGGTTGACGAAGAGGAGGCCTGGATCAGCGAGAAGCAGCAGCTGGTGGCGGTGGGCGAGTGCGGAGACAGCATGGCGGCGGTGCAGGGCCTGCTGAAGAAGCACGAGGCGCTGGAGGCGGAGCTGGCGGCGCGCGGCGAGCGGGTGCGCGAGCTGGCGGCGGCGGGCGACGCGCTGCTGGCGGCCGGCAACCTGCACCACGACGCGCTGGCGCACCGCATCCGCGCCCTGCAGGCCAAACTGGAAAAGCTCACGGCATTGGCGGCTCGTCGCAAGGTAGCCCTTGTAGACAACTCCCTCTATCTGCAGCTACTGTGGAAGGCCGACGTGGTGGAATCCTGGATCGCAGACAAGGAGACACACGTGCGATCTGATGAGTTCGGTCGAGATCTGTCCACTGTGCAGACATTGCTCACCAAGCAAGACACTTTCGATGCTGGTCTGGCGGCGTTCGAGCACGAAGGGATCCAGAACATCACGTCTCTGAAAGAGCAGCTGGTGGCGGCGGGGCACGAGCAGACGCCCGCCATCGTGAAGCGGCACGGTGACGTCATCGCGCGCTGGCAGCGACTGCTCTCCGACTCCGCCACCAGGAAGCAACGGCTGCTGCAGCTGCAGGACCAGTTCCGACAGATCGAGGAACTCTACCTCACCTTCGCCAAAAAGGCTTCTGCATTCAACTCGTGGTTCGAGAACGCGGAGGAGGACCTGACGGACCCCGTGCGCTGCAACTCCATCGAGGAGATACGCGCGCTCAAGGACGCGCACGCGCAGTTCCAGGCGAGTGACCCACGCATATTCCAACTGTATCCCGCCTCGGAGCGAGACGTGGAGTTGTCGAAGGAAGCTCAACGGCAGGAGGAGAACGACAAGCTGCGGAAGGAGTTCGCCAAGCACGCCAACACCTTCCACCAGTGGCTCACCGAGACTCGGTACCGGTTGCTAGGCTGGGACGGCACATCAATGATGGAGGGCACGGGTTCCCTGGAACAACAGTTGGCGACGCTGCGCCAACGAGCGTCCGAAGTACGCGCCCGCAGAGCTGACCTGAGACGCCTTGAAGAGTTAGGCGCCGCCCTGGAGGAGCATCTGATCCTGGACAACCGCTACACGGAGCACAGCACCGTGGGACTAGCGCAGCAGTGGGACCAGCTGGACCAGCTCTCTATGCGCATGCAGCACAACCTCGAGCAGCAGATACAAGCCAGGAACCATTCCGGTGTAAGCGAAGACGCCCTGAAGGAGTTCTCGATGATGTTCAAGCACTTCGACAAGGATCGATCTGGACGCCTCAACCACCACGAGTTCAAGTCGTGTCTGCGAGCCCTCGGGTACGACCTGCCCATGGTTGAAGAGGGACAACCCGATCCTGAGTTTGAATCTATACTCAGTATCGTAGATCCGAACCGCGACGGCCAAGTATCCCTTCAAGAGTACATGGCCTTCATGATCAGCAAGGAGACCGAGAACGTGCACTCCTCCGAGGAGATCGAGAACGCGTTCCGCGCCATCACCGCGCACCAGGACCGGCCCTACGTCACCAAGGAAGAACTGTACGCGAACCTCACGAAGGAGATGGCGGACTACTGCGTGGCGCGCATGAAGCCCTACGTGGAGCCGAAGACGGAGCGCCCCATACCCAACGCGCTCGACTACATCGACTTCACACACACTCTGTTCCAAAACTAA

Protein

MEQIPPPKEVKILETAEDIQERREEVLNRYEEFKQEARAKREKLEDSRRFQYFKRDADELESWIQEKLQAASDESYKDPTNLQAKIQKHQAFEAEVAAHSNAIVVLDNTGSEMIAAGHFASETIRRRLDELHRLWELLLSRLAEKGMKLQQALVLVQFLRHCDEVMFWIHDKETFVCADEFGSDLEHVEVLQRKFDEFQKDMAAQEYRVTEVNQLAERLVLEGHPERETIVKRKDELNEAWQRLRQMALMRQERLFGAHEIQRFNRDADETIAWISEKDAVLGSDDYGRDLATVQTLQRKHEGVERDLAALEDKVSVLEGEAVRLGAIHGAHADAISAKRDEAHAAWQRLVQRAAHRRQRLEAALALHRFLADYRDLLSWLADMRALIAADDLAKDVPGAEALLERHQEHKGEMDARADVIGACAVAGQALVASEHHAAADVSAALHTLEREAAALQQLWEQRRVLYLQCMDLQLFYRDTEQADAWMHKQEAFLANEDVGDSLDSVEALLKKHEDFEKSLAAQEEKIKALDEFATKLIEGNHYAADDVAQRREMLLERRAALLEKSNQRRALLEDAYKYQQFERDCDETKGWVNEKLKFATDDSYLDPTNLNGKVQKHQNFEQELQANKPRVDEITAVGKRLLELEHFAQPQISSRVEELGGIWERLVQSSELKGNKLQEAAQQQQYNRAVEDIELWLSEVEGQLLSEDYGKDLTSVQNLQKKHALLEADVSSHAERIDAIRNQAEQFIEKGHFDADNIKAKRDALVGRYAALDAPMAVRKRRLLDSLQAQQLFRDLDDEAAWIREKEPVIASTNRGRDLIGVQNLMKKHQAVLGEMAQHEARVEAVRAAGAALRDAGHFAAADIAARLTQLRDNWTQLQEKALQRKQDLEDSLQAQQYFADANEAESWMREKEPIACTQDYGKDEDSSEALLKKHEALLSDLEAFGNTIKSLREQANSCRQQESPVVDESGKECVAALYDYAEKSPREVSMKRGDVLTLLNSNNKDWWKVEVNDRQGFVPAAYVKKIDAGLSSSQQNLADSNSIAARQNQIESQYDNLLGLARERQNKLNETVKAYVLVREAAELATWIKDKEMHAQVQDVGEDLEQVEVMQKKFDDFQNDLRANEVRLAEMNEIAVQLMTVGQTEAALKIKTQMQELNSKWSSLQQLTAERAAQLGSAHEVQRFHRDVDETKDWIAEKDAALASDDLGRDLRSVQTLQRKHEGLERDLAALGDKIRQLDDTANRLMSTHGDSADATYSKQIEINEAWQQLQARANARKEKLLDSYDLQRFLSDYRDLMAWINSMMALVSSDELANDVTGAEALLERHQEHRTEMDARAGTFQALELFGQQLLQGGHYASVDIQEKLNNMSDARQELEKAWVNRRMKLDQNLELQLFYRDCEQAEGWMAAREAFLAPADHADSADQQQPDNVEQLIKKHEDFDKAINAHEEKIAQLQTLADQLIASDHYATDDIDDKRKQVLDRWRHLKEALIEKRSRLGDEQTLQQFSRDADEMENWIMEKMQLATEESYKDPTNIQSKHQKHQAFEAELAANAERIQSVLAMGGNLVQRGQCSGSEDAVQARLASIADQWEYLTQKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVESLLTSEDSGKDLASVQNLMKKHQLVEADIQAHEDRINDMNGQADALVESGQFDSAGIGSRRDAINERFERVRNLAAHRRARLHEANTLHQFFRDIADEESWIKEKKLLVASDDYGRDLTGVQNLLKKHKRLEAELASHEPAIQAVQEAGEKLMDVSNLGVLEIEQRLKALALAWDELQALAAERGAKLQQSLAYQQFLAKVDEEEAWISEKQQLVAVGECGDSMAAVQGLLKKHEALEAELAARGERVRELAAAGDALLAAGNLHHDALAHRIRALQAKLEKLTALAARRKVALVDNSLYLQLLWKADVVESWIADKETHVRSDEFGRDLSTVQTLLTKQDTFDAGLAAFEHEGIQNITSLKEQLVAAGHEQTPAIVKRHGDVIARWQRLLSDSATRKQRLLQLQDQFRQIEELYLTFAKKASAFNSWFENAEEDLTDPVRCNSIEEIRALKDAHAQFQASDPRIFQLYPASERDVELSKEAQRQEENDKLRKEFAKHANTFHQWLTETRYRLLGWDGTSMMEGTGSLEQQLATLRQRASEVRARRADLRRLEELGAALEEHLILDNRYTEHSTVGLAQQWDQLDQLSMRMQHNLEQQIQARNHSGVSEDALKEFSMMFKHFDKDRSGRLNHHEFKSCLRALGYDLPMVEEGQPDPEFESILSIVDPNRDGQVSLQEYMAFMISKETENVHSSEEIENAFRAITAHQDRPYVTKEELYANLTKEMADYCVARMKPYVEPKTERPIPNALDYIDFTHTLFQN

Description

Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi-derived membrane secretion required for the formation of furrows during cellularization.

Subunit

Native spectrin molecule is a tetramer composed of two antiparallel heterodimers joined head to head so that each end of the native molecule includes the C-terminus of the alpha subunit and the N-terminus of the beta subunit. Interacts with calmodulin in a calcium-dependent manner, interacts with F-actin and also interacts with Lva. Interacts with Ten-m.

Miscellaneous

Its transcript shares the first untranslated exon with the dlt transcript, suggesting a common regulation.

Similarity

Belongs to the spectrin family.

Keywords

3D-structure   Actin capping   Actin-binding   Calcium   Calmodulin-binding   Cell shape   Complete proteome   Cytoplasm   Cytoskeleton   Golgi apparatus   Metal-binding   Phosphoprotein   Reference proteome   Repeat   SH3 domain  

Feature

chain  Spectrin alpha chain

Uniprot

A0A1E1WR33   A0A2H1VAD9   A0A173FDD0   S4PH37   A0A212FB96   A0A437BXV0   + More
A0A2J7QVA1   A0A2J7QV98   A0A067RUI8   A0A069DXZ1   A0A1S3DD98   A0A224X4N5   A0A0V0G435   A0A2J7QVA8   A0A0K8SCT5   E0VV65   A0A0P4VTQ5   V9IJN9   A0A0K8TCJ0   A0A158NIL4   T1HPS9   A0A088ACE3   E9I8D6   A0A0C9R692   A0A151J4T0   A0A151XDV2   A0A195BCT0   A0A158NIL3   A0A2A3EFW3   A0A026W3N3   A0A151IP53   E2AX44   A0A195FLX6   A0A1W4XPA6   A0A411G645   A0A154P796   E2BFC6   K7J3F4   A0A1Y1LRY4   A0A0R1DUS3   A0A0Q5U4D6   D6W8J4   M9PDQ0   A0A0Q9XL73   A0A0P8ZSY5   A0A1W4W6C4   W8ANY7   F4WS96   A0A0R3P5Q6   A0A0Q5U2Q0   A0A0Q9XBE9   P13395   A0A232FF24   A0A0R1DZX8   A0A0Q5U8T3   A0A0R1DUG6   A0A1W4VTS2   A0A034VFQ9   A0A0Q9XAW4   A0A1I8ME62   A0A0P8Y852   W8B358   A0A0P9C1U7   T1PNU9   M9PGV6   A0A1Y1LU64   A0A1I8QDV7   A0A0Q9W9D3   A0A0L0CNI9   Q29EZ8   B4MXT6   A0A1L8E5B8   A0A0A1WZX6   A0A3B0KFZ2   B4KXU7   A0A1A9V2Y6   A0A1Q3FEY7   B4HW03   A0A1B0B477   A0A0R3P5T5   A0A2S2PAP5   A0A2H8TYT6   A0A1A9W748   A0A1I8ME59   B3M7A4   Q16EQ1   T1PDG2   A0A1I8ME61   A0A0M4F0U0   A0A0K8UAC6   A0A034VI07   M9PBI5   B4PDU1   B3NEV4   A0A1I8QDR3   A0A182H9F8   A0A1I8QDP4   A0A2S2QHA8   B4MGM3   A0A0A1XG25  

Pubmed

27251284    23622113    22118469    24845553    26334808    20566863    + More
27129103    26823975    21347285    21282665    24508170    30249741    20798317    20075255    28004739    17994087    17550304    18362917    19820115    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    24495485    21719571    15632085    2808524    8276898    12537569    3680372    11076973    2497103    14667407    17372656    18327897    22426000    8266097    28648823    18057021    25348373    25315136    26108605    25830018    17510324    26483478   

EMBL

GDQN01001748    JAT89306.1    ODYU01001486    SOQ37756.1    KT182638    ANG83465.1    + More
GAIX01003407    JAA89153.1    AGBW02009363    OWR50993.1    RSAL01000001    RVE55210.1    NEVH01010478    PNF32510.1    PNF32509.1    KK852460    KDR23504.1    GBGD01000026    JAC88863.1    GFTR01008961    JAW07465.1    GECL01003684    JAP02440.1    PNF32511.1    GBRD01014730    JAG51096.1    DS235803    EEB17271.1    GDKW01000580    JAI56015.1    JR050446    AEY61280.1    GBRD01002548    GDHC01007121    JAG63273.1    JAQ11508.1    ADTU01016945    ADTU01016946    ACPB03012376    ACPB03012377    GL761538    EFZ23210.1    GBYB01011829    JAG81596.1    KQ980088    KYN17783.1    KQ982254    KYQ58537.1    KQ976513    KYM82376.1    KZ288256    PBC30627.1    KK107503    QOIP01000006    EZA49654.1    RLU21479.1    KQ976891    KYN07257.1    GL443520    EFN61994.1    KQ981430    KYN41700.1    MH365539    QBB01348.1    KQ434831    KZC07799.1    GL448009    EFN85586.1    GEZM01048770    JAV76419.1    CM000159    KRK00797.1    CH954178    KQS43116.1    KQ971312    EEZ99233.1    AE014296    AGB93983.1    CH933809    KRG05646.1    CH902618    KPU77622.1    GAMC01018838    JAB87717.1    GL888307    EGI62932.1    CH379070    KRT08481.1    KQS43115.1    KRG05645.1    M26400    BT023889    S67762    S67765    AY069741    NNAY01000310    OXU29302.1    KRK00794.1    KQS43114.1    KQS43117.1    KRK00795.1    KRK00796.1    GAKP01016822    GAKP01016821    JAC42131.1    KRG05647.1    KPU77623.1    GAMC01018839    JAB87716.1    KPU77621.1    KA649638    AFP64267.1    AGB93981.1    GEZM01048771    JAV76418.1    CH940682    KRF77567.1    JRES01000247    KNC33004.1    EAL29911.1    CH963876    EDW76855.1    GFDF01000153    JAV13931.1    GBXI01010096    JAD04196.1    OUUW01000009    SPP85249.1    EDW17619.1    GFDL01008932    JAV26113.1    CH480817    EDW50118.1    JXJN01008189    KRT08482.1    GGMR01013845    MBY26464.1    GFXV01007639    MBW19444.1    EDV38765.1    CH478619    EAT32709.1    KA646827    AFP61456.1    CP012525    ALC44812.1    GDHF01028761    GDHF01025122    GDHF01013738    GDHF01013593    GDHF01009620    GDHF01002806    JAI23553.1    JAI27192.1    JAI38576.1    JAI38721.1    JAI42694.1    JAI49508.1    GAKP01016823    GAKP01016820    JAC42129.1    AGB93982.1    EDW92906.1    EDV50227.1    JXUM01030164    JXUM01030165    GGMS01007914    MBY77117.1    EDW57089.1    GBXI01003963    JAD10329.1   

Proteomes

UP000007151    UP000283053    UP000235965    UP000027135    UP000079169    UP000009046    + More
UP000005205    UP000015103    UP000005203    UP000078492    UP000075809    UP000078540    UP000242457    UP000053097    UP000279307    UP000078542    UP000000311    UP000078541    UP000192223    UP000076502    UP000008237    UP000002358    UP000002282    UP000008711    UP000007266    UP000000803    UP000009192    UP000007801    UP000192221    UP000007755    UP000001819    UP000215335    UP000095301    UP000095300    UP000008792    UP000037069    UP000007798    UP000268350    UP000078200    UP000001292    UP000092460    UP000091820    UP000008820    UP000092553    UP000069940   

PRIDE

M9PDQ0    P13395    M9PGV6    M9PBI5   

Pfam

PF00018   SH3_1        + More
PF00435   Spectrin
PF08726   EFhand_Ca_insen
PF13499   EF-hand_7
PF15296   Codanin-1_C

Interpro

IPR018247   EF_Hand_1_Ca_BS        + More
IPR014837   EF-hand_Ca_insen       
IPR035825   Alpha_Spectrin_SH3       
IPR018159   Spectrin/alpha-actinin       
IPR001452   SH3_domain       
IPR011992   EF-hand-dom_pair       
IPR036028   SH3-like_dom_sf       
IPR002048   EF_hand_dom       
IPR002017   Spectrin_repeat       
IPR028171   Codanin-1_C       

SUPFAM

SSF47473   SSF47473        + More
SSF50044   SSF50044       

CDD

cd00051  EFh
cd11808  SH3_Alpha_Spectrin

ProteinModelPortal

A0A1E1WR33   A0A2H1VAD9   A0A173FDD0   S4PH37   A0A212FB96   A0A437BXV0   + More
A0A2J7QVA1   A0A2J7QV98   A0A067RUI8   A0A069DXZ1   A0A1S3DD98   A0A224X4N5   A0A0V0G435   A0A2J7QVA8   A0A0K8SCT5   E0VV65   A0A0P4VTQ5   V9IJN9   A0A0K8TCJ0   A0A158NIL4   T1HPS9   A0A088ACE3   E9I8D6   A0A0C9R692   A0A151J4T0   A0A151XDV2   A0A195BCT0   A0A158NIL3   A0A2A3EFW3   A0A026W3N3   A0A151IP53   E2AX44   A0A195FLX6   A0A1W4XPA6   A0A411G645   A0A154P796   E2BFC6   K7J3F4   A0A1Y1LRY4   A0A0R1DUS3   A0A0Q5U4D6   D6W8J4   M9PDQ0   A0A0Q9XL73   A0A0P8ZSY5   A0A1W4W6C4   W8ANY7   F4WS96   A0A0R3P5Q6   A0A0Q5U2Q0   A0A0Q9XBE9   P13395   A0A232FF24   A0A0R1DZX8   A0A0Q5U8T3   A0A0R1DUG6   A0A1W4VTS2   A0A034VFQ9   A0A0Q9XAW4   A0A1I8ME62   A0A0P8Y852   W8B358   A0A0P9C1U7   T1PNU9   M9PGV6   A0A1Y1LU64   A0A1I8QDV7   A0A0Q9W9D3   A0A0L0CNI9   Q29EZ8   B4MXT6   A0A1L8E5B8   A0A0A1WZX6   A0A3B0KFZ2   B4KXU7   A0A1A9V2Y6   A0A1Q3FEY7   B4HW03   A0A1B0B477   A0A0R3P5T5   A0A2S2PAP5   A0A2H8TYT6   A0A1A9W748   A0A1I8ME59   B3M7A4   Q16EQ1   T1PDG2   A0A1I8ME61   A0A0M4F0U0   A0A0K8UAC6   A0A034VI07   M9PBI5   B4PDU1   B3NEV4   A0A1I8QDR3   A0A182H9F8   A0A1I8QDP4   A0A2S2QHA8   B4MGM3   A0A0A1XG25  

PDB

1U4Q     E-value=1.86585e-73,     Score=709

KEGG

101735654    K06114 spectrin alpha | (RefSeq) spectrin alpha chain

GO

GO:0005509   GO:0004725   GO:0005861   GO:0006937   GO:0051015   GO:0048306   GO:0003009   GO:0007417   GO:0005886   GO:0008360   GO:0045170   GO:0048790   GO:0007308   GO:0008017   GO:0007294   GO:0045478   GO:0007009   GO:0031594   GO:0030727   GO:0030707   GO:0048134   GO:0008092   GO:0016323   GO:0003779   GO:0042062   GO:0050807   GO:0005938   GO:0045169   GO:0005794   GO:0007274   GO:0051693   GO:0008091   GO:0007026   GO:0016199   GO:0005516   GO:0005515   GO:0006468   GO:0018024   GO:0007165   GO:0016620   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

Subcellular location

Cytoplasm  
Cytoskeleton  
Golgi apparatus  

Length:

2392

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00023

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00002

outside

1  -  2392

 

 

Pi

3.64528

Theta

19.126173

Tajima's D

-1.391803

CLR

169.198995

CSRT

0.0711464426778661

Interpretation

Uncertain