Silkworm Genome Informatics Database

Gene

KWMTBOMO08646 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007949

Annotation

PREDICTED:_uncharacterized_protein_DDB_G0283697-like_isoform_X2_[Papilio_machaon]

Location

Bomo_Chr15(-):1551288-1552522 View in EpiBrowser

Full name

Delta-aminolevulinic acid dehydratase

Location in the cell

Nuclear Reliability : 4.548

CDS

ATGAATACGGAAACCGAACCATCTCCAAAGAAAAAGACAGACAAAATCACAGACAACCTCACAGTCTCACTGGAAAAGTGCGACATCAAGAAAATAGAAAAAAGTGACGAAGAACCGAAGCCTCGAATCGTATTAACCATACGCTCGGAGAAGTCTAATGCTAAAAATAGTAATATGAAGGTAGTATCCACGGAAGAAAAACAAGAAGAGTTCTGTCCTCGCAGATCCAGCAGGACACGAGGTAAATGGGAATGGGTCTGTGACAGCGATACATCTACTTCACCTAAAAAAGATAAATCCGCATCGGAGAACGACGAGTGTGACATTCTTACCACAAAAAGGTCAACTAGCCGTAGAAACAAAGATAGTGACAATGTTGTTGCCAATGCTATTGCAAGAAAAGAAAAAATGTATGATATTATTACACCACAGCGCTCTACACGACGACAAAAAGCAAAACCCGTAGAAGAAGTGGCTCACGAGACAGTGGATAAAGGTGTAAGAACTAGAAGATCAGCTAGACCTGATCCTGTGGAACCAGATACTAAAAATAAGGGAAAAGATGCAGAACAAGACGTGATTGAGATTGGCACAGATGACGACACCCTCAGCCAAAGCTCAGATATGAAATTAAAACACCTGTGTGAATTGGGCTTGAAAGCTATTAACCCTGAAGAAGAGGAGGATGAAGATTATGTTGATGGCCGGTTGGTATAA

Protein

MNTETEPSPKKKTDKITDNLTVSLEKCDIKKIEKSDEEPKPRIVLTIRSEKSNAKNSNMKVVSTEEKQEEFCPRRSSRTRGKWEWVCDSDTSTSPKKDKSASENDECDILTTKRSTSRRNKDSDNVVANAIARKEKMYDIITPQRSTRRQKAKPVEEVAHETVDKGVRTRRSARPDPVEPDTKNKGKDAEQDVIEIGTDDDTLSQSSDMKLKHLCELGLKAINPEEEEDEDYVDGRLV

Catalytic Activity

2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen

Subunit

Homooctamer.

Similarity

Belongs to the ALAD family.

Uniprot

H9JEK2 A0A2H1WX12 A0A2A4K674 A0A2A4K646 A0A2A4K6U1 A0A0N1IGD6 + More
A0A194PPK7 A0A3S2P8U2 A0A212FB81

EC Number

4.2.1.24

Pubmed

19121390 26354079 22118469

EMBL

BABH01003235 BABH01003236 BABH01003237 ODYU01011696 SOQ57600.1 NWSH01000087 + More
PCG79737.1 PCG79735.1 PCG79736.1 KQ460497 KPJ14333.1 KQ459596 KPI95376.1 RSAL01000001 RVE55212.1 AGBW02009363 OWR50996.1

Proteomes

UP000005204 UP000218220 UP000053240 UP000053268 UP000283053 UP000007151 + More

PRIDE

H9JEK2

Pfam

PF05033   Pre-SET        + More
PF00490   ALAD
PF12796   Ank_2
PF00856   SET
PF00023   Ank

Interpro

IPR002110   Ankyrin_rpt        + More
IPR001214   SET_dom
IPR030656   ALAD_AS
IPR001731   ALAD
IPR007728   Pre-SET_dom
IPR013785   Aldolase_TIM
IPR020683   Ankyrin_rpt-contain_dom
IPR036770   Ankyrin_rpt-contain_sf

SUPFAM

SSF48403 SSF48403

Gene 3D

1.25.40.20 3.20.20.70

CDD

cd00204 ANK

ProteinModelPortal

H9JEK2 A0A2H1WX12 A0A2A4K674 A0A2A4K646 A0A2A4K6U1 A0A0N1IGD6 + More
A0A194PPK7 A0A3S2P8U2 A0A212FB81

KEGG

101743644 K11420 euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] | (RefSeq) histone-lysine N-meth

PATHWAY

00310 Lysine degradation - Bombyx mori (domestic silkworm)

GO

GO:0018024 GO:0005634 GO:0005694 GO:0006779 GO:0008270 GO:0004655 GO:0046872 GO:0002039

PANTHER

PTHR11458

Subcellular location

Chromosome
Nucleus

Length:

238

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.06210

outside

1 - 238

Pi

300.03747

Theta

205.98383

Tajima's D

1.424207

CLR

0

CSRT

0.769611519424029

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics