Gene

KWMTBOMO08644  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007949

Annotation

putative_histone-lysine_N-methyltransferase?_H3_lysine-9_specific_[Danaus_plexippus]

Location

Bomo_Chr15(-):1532492-1545552      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.322

CDS

ATGGAAGTGGACCACGAAAAGGACGAAGAGAACGAGAAACCAGAAGCAGAAGCAGAACACAGTGACGGAGAAGAGAAGGCAACGTTAGGGGCAGTCGAAAGGGAGAAACCGAACGATGAAGACTTGATGAGGGTCATAAGATACCTGATAGCGGCCGGCTGCGACTTGAACGCCGCCGATTCGGAAGGCATGACGGCTCTCCACATAGCGGCCCAGCACGGGGACGCGGCTGTGTGCGGCGCGCTGCTGTCCGCGGGCGCCGAGGTGGACGCGCGCGACCAGGGCGGCTGGACCCCGCTCGTCTGGGCCGTCGAGAACGATTATGCCGACGTTGTCAGGCTACTGCTGCGCGAAGGAGCGGACGCGCTGTCCGTGGACAAGGAGGGCAACAGCGCGGTGCACTGGTGCGCGGCAGCCGGCTCCTCCCGCGCGCTGCCGCTGCTCGCCGCCGCCGCGCCCGCCGCCGCGCACGCGCACAACGCGCACCTCGACACGCCGCTACATGTCGCAGCGAGACAAGGCCACTACTCGTGCGTCGTGATCCTGCTGGCCAGAGGCGCCAAGACGGACGTTGCGAATTCTTCCGGGGAGCTCCCGATCGACGTGGCTACAGACCCCAGCCGGCGCGCCATCTCGCTCAGCATGCAGATGAATCTCGCGGTCACAGAGAAGCTCGGCCAGCGAAACGTTCTATCCTTTGACATTTCGAATGGGTGCGAGATGTATCCGATACCGTGCGTCAACGAAGTGGACTCTACCCCGCTGCCCGACGACTTCGTGTACGTCACGTCGCACGTCATGCCCACGCAGATCCCCATAGACAACACCATACAGACGATGCAGGGCTGCACGTGCAAGGAGGGCTCGTGTTCGTCGGAGTCGTGCGCGTGCTGCGTGCTGTCGGTGCGGCGCTGGGCGCGCGCGGGCCGCCTGCCGCCCAACTTCCCGCACCACGACCCGCCCGTACTCTTCGAATGCAACGCCACCTGCGCGTGTAACAAGAAGAAGTGTACGAATAACTTGGTGGGCAAGCTGTCCTCGCGCGGCGCGACGTTCGTCCGCACGGAGGTGTACCGGTGCGCGGGGGGCGCGGGGTGGGGGCTGCGCGCGCGCGAGGCGGTGCCGCGGGGCGCGCCGCTCGCGCTGTACTGCGGGGAGCTGCTCGCCTCCGCCGTGGCCGACACCAGGCCCACCGACCATTACATGTTCTCACTTGATCTCAAGCCGGATCTCCTCGAGCAATGTGCGGACAAGACGCAGCTGTGCATAGACGCGGCGTCGTACGGCAGCGCGGCCCGCTTCATGAACCACAGCTGCGAGGCGAGCGCGGCCGCCGTCCGCGTGTTCACCCGCCACCGCGACCTACGCCTGCCGCTCGTCGTCCTGTTCGCGACTAGGGACATACACCCAGGAGAACCGCTCACTTTTGACTACGGCGACAAGTTTTGGGCAATAAAAGCAAAGTGGATGAGATGCGAGTGCGGCGCTCCCGACTGCAGGTATCCGGTGAAAGGGGGCACTAACAACGACAGTAATTAA

Protein

MEVDHEKDEENEKPEAEAEHSDGEEKATLGAVEREKPNDEDLMRVIRYLIAAGCDLNAADSEGMTALHIAAQHGDAAVCGALLSAGAEVDARDQGGWTPLVWAVENDYADVVRLLLREGADALSVDKEGNSAVHWCAAAGSSRALPLLAAAAPAAAHAHNAHLDTPLHVAARQGHYSCVVILLARGAKTDVANSSGELPIDVATDPSRRAISLSMQMNLAVTEKLGQRNVLSFDISNGCEMYPIPCVNEVDSTPLPDDFVYVTSHVMPTQIPIDNTIQTMQGCTCKEGSCSSESCACCVLSVRRWARAGRLPPNFPHHDPPVLFECNATCACNKKKCTNNLVGKLSSRGATFVRTEVYRCAGGAGWGLRAREAVPRGAPLALYCGELLASAVADTRPTDHYMFSLDLKPDLLEQCADKTQLCIDAASYGSAARFMNHSCEASAAAVRVFTRHRDLRLPLVVLFATRDIHPGEPLTFDYGDKFWAIKAKWMRCECGAPDCRYPVKGGTNNDSN

Catalytic Activity

L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine

Uniprot

A0A3S2P8U2   A0A212FB81   A0A194PPK7   A0A2H1WVV3   A0A1B6F0M7   A0A1B6FXA0   + More
A0A1B6M515   A0A1B6ECU3   A0A1Y1JUN3   F7CR04   V9KGP7   V9KE63   A0A087V491   E0VU86   Q8BP38   Q5ZLI5   A0A401S3E7   A0A3Q1HAT4   A0A226PMU1   A0A226NG00   A0A091SQI4   V9K7N3   A0A0P4W5Y4   G3WHW7   A0A0P4W139   A0A402F2E6   G3UQS6   G1MU25   A0A093SJC5   A0A3Q3FEB3   A0A1Y1JYZ3   A0A087YIA8   A0A452HCH5   A0A1D5PVY2   A0A091QV00   A0A3B3XNE2   H0YXA8   A0A1V4J783   Q5F3R1   A0A3Q2U3H4   A0A3Q3RJS4   A0A061IM00   A0A218UDV4   A0A1D5PIX7   G1KKX8   A0A1D5PJ82   A0A3B3UDZ9   A0A1V4J7B8   A0A3B4AGX7   A0A1D5P0G7   Q5F3H1   A0A3P9Q7R1   A0A1D5PW08   K7FDM7   R0L5Y1   U3JSN1   K7FDN4   M7AUL5   A0A061IJI4   A0A3Q1IN21   A0A151MF76   A0A3Q1HAL4   F6UJH7   A0A3Q1IMZ5   N6T864   A0A3M0IXE2   A0A1D5P7T6   A0A151MF43   A0A151MF60   U4UEE7   A0A1U7SD70   C0PUU7   A0A3B3HIQ6   A0A0G2JRR0   A0A3L8SDY2   A0A151PIL3   H2MFC5   A0A3P9LUJ9   A0A091IZR3   A0A151MFI4   A0A3B3I9U5   A0A3B3CA89   A0A1A6G2T1   A0A3P9K7J6   H3AYZ4   A0A3B3CCK6   A0A3P9IEC1   A0A0G2JRN8   A0A3P9JN02   A0A3B3CCV7   G3NEW1   I3K510   A0A091CT20   A0A1S3WET1   W5M0N2   A0A3B3CBF5  

Pubmed

22118469    26354079    28004739    20431018    24402279    20566863    + More
10349636    11042159    11076861    11217851    12466851    16141073    15642098    30297745    24621616    21709235    20838655    28562605    15592404    20360741    23929341    25463417    17381049    23624526    22293439    17495919    23537049    17554307    14574404    17525332    18669648    21406692    23186163    24275569    28112733    30282656    29451363    9215903    25186727   

EMBL

RSAL01000001    RVE55212.1    AGBW02009363    OWR50996.1    KQ459596    KPI95376.1    + More
ODYU01011450    SOQ57190.1    GECZ01026356    JAS43413.1    GECZ01014944    JAS54825.1    GEBQ01008965    JAT31012.1    GEDC01001604    JAS35694.1    GEZM01100137    JAV52999.1    AAMC01112932    JW864543    AFO97060.1    JW864046    AFO96563.1    KL479275    KFO07433.1    DS235783    EEB16942.1    AK077743    BAC36989.1    AJ719749    CAG31408.1    BEZZ01000071    GCC24943.1    AWGT02000046    OXB80677.1    MCFN01000062    OXB66474.1    KK931406    KFQ45237.1    JW861560    AFO94077.1    GDRN01080877    JAI62117.1    AEFK01023222    AEFK01023223    AEFK01023224    AEFK01023225    AEFK01023226    AEFK01023227    AEFK01023228    AEFK01023229    AEFK01023230    AEFK01023231    GDRN01080876    JAI62118.1    BDOT01000084    GCF50544.1    KL671500    KFW82784.1    GEZM01100136    JAV53000.1    AYCK01017089    AYCK01017090    AADN05000150    KK804840    KFQ31380.1    ABQF01048574    ABQF01048575    ABQF01048576    ABQF01048577    ABQF01048578    ABQF01048579    ABQF01048580    LSYS01008925    OPJ67914.1    AJ851589    CAH65223.1    KE665405    ERE88816.1    MUZQ01000386    OWK51903.1    OPJ67915.1    AJ851679    CAH65313.1    AGCU01190420    AGCU01190421    AGCU01190422    AGCU01190423    AGCU01190424    AGCU01190425    AGCU01190426    AGCU01190427    AGCU01190428    AGCU01190429    KB744204    EOA95687.1    AGTO01021651    KB563898    EMP28409.1    ERE88815.1    AKHW03006215    KYO23151.1    APGK01047873    KB741092    ENN73908.1    QRBI01000209    RMB93514.1    KYO23148.1    KYO23149.1    KB632050    ERL88300.1    BT072769    ACN60342.1    BX005460    QUSF01000027    RLW00329.1    AKHW03000171    KYO48936.1    KL218434    KFP05071.1    KYO23150.1    LZPO01107916    OBS60105.1    AFYH01003668    AFYH01003669    AFYH01003670    AFYH01003671    AFYH01003672    AFYH01003673    AFYH01003674    AFYH01003675    AERX01004722    AERX01004723    AERX01004724    AERX01004725    AERX01004726    KN124473    KFO21058.1    AHAT01021783   

Proteomes

UP000283053    UP000007151    UP000053268    UP000008143    UP000009046    UP000287033    + More
UP000265040    UP000198419    UP000198323    UP000007648    UP000288954    UP000001645    UP000053258    UP000264800    UP000028760    UP000291020    UP000000539    UP000261480    UP000007754    UP000190648    UP000261640    UP000030759    UP000197619    UP000001646    UP000261500    UP000261520    UP000242638    UP000007267    UP000016665    UP000031443    UP000050525    UP000002280    UP000019118    UP000269221    UP000030742    UP000189705    UP000001038    UP000005640    UP000276834    UP000265180    UP000054308    UP000261560    UP000092124    UP000008672    UP000265200    UP000007635    UP000005207    UP000028990    UP000079721    UP000018468   

PRIDE

Q5F3H1   

Pfam

PF05033   Pre-SET        + More
PF00856   SET
PF12796   Ank_2
PF00023   Ank
PF05485   THAP

Interpro

IPR002110   Ankyrin_rpt        + More
IPR001214   SET_dom       
IPR007728   Pre-SET_dom       
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR038034   EHMT2       
IPR038035   EHMT1       
IPR003616   Post-SET_dom       
IPR006612   THAP_Znf       
IPR038441   THAP_Znf_sf       

SUPFAM

SSF48403   SSF48403       

Gene 3D

1.25.40.20     3.30.40.180    

CDD

cd00204  ANK

ProteinModelPortal

A0A3S2P8U2   A0A212FB81   A0A194PPK7   A0A2H1WVV3   A0A1B6F0M7   A0A1B6FXA0   + More
A0A1B6M515   A0A1B6ECU3   A0A1Y1JUN3   F7CR04   V9KGP7   V9KE63   A0A087V491   E0VU86   Q8BP38   Q5ZLI5   A0A401S3E7   A0A3Q1HAT4   A0A226PMU1   A0A226NG00   A0A091SQI4   V9K7N3   A0A0P4W5Y4   G3WHW7   A0A0P4W139   A0A402F2E6   G3UQS6   G1MU25   A0A093SJC5   A0A3Q3FEB3   A0A1Y1JYZ3   A0A087YIA8   A0A452HCH5   A0A1D5PVY2   A0A091QV00   A0A3B3XNE2   H0YXA8   A0A1V4J783   Q5F3R1   A0A3Q2U3H4   A0A3Q3RJS4   A0A061IM00   A0A218UDV4   A0A1D5PIX7   G1KKX8   A0A1D5PJ82   A0A3B3UDZ9   A0A1V4J7B8   A0A3B4AGX7   A0A1D5P0G7   Q5F3H1   A0A3P9Q7R1   A0A1D5PW08   K7FDM7   R0L5Y1   U3JSN1   K7FDN4   M7AUL5   A0A061IJI4   A0A3Q1IN21   A0A151MF76   A0A3Q1HAL4   F6UJH7   A0A3Q1IMZ5   N6T864   A0A3M0IXE2   A0A1D5P7T6   A0A151MF43   A0A151MF60   U4UEE7   A0A1U7SD70   C0PUU7   A0A3B3HIQ6   A0A0G2JRR0   A0A3L8SDY2   A0A151PIL3   H2MFC5   A0A3P9LUJ9   A0A091IZR3   A0A151MFI4   A0A3B3I9U5   A0A3B3CA89   A0A1A6G2T1   A0A3P9K7J6   H3AYZ4   A0A3B3CCK6   A0A3P9IEC1   A0A0G2JRN8   A0A3P9JN02   A0A3B3CCV7   G3NEW1   I3K510   A0A091CT20   A0A1S3WET1   W5M0N2   A0A3B3CBF5  

PDB

4NVQ     E-value=2.96847e-45,     Score=459

KEGG

101743644    K11420 euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] | (RefSeq) histone-lysine N-meth

GO

GO:0005634   GO:0005694   GO:0018024   GO:0008270   GO:0002039   GO:0051570   GO:0031017   GO:0060219   GO:0004623   GO:0102568   GO:0102567   GO:0016604   GO:0018027   GO:0120162   GO:0006306   GO:0045995   GO:0018026   GO:0000122   GO:0070742   GO:0046974   GO:0046976   GO:1990841   GO:0036166   GO:0010424   GO:0071314   GO:0048665   GO:0007130   GO:1902902   GO:0007286   GO:0009566   GO:0000977   GO:0006275   GO:0016607   GO:0035265   GO:0048148   GO:0003677   GO:0005515   GO:0007165   GO:0016620   GO:0006418   GO:0003676   GO:0016876   GO:0043039   GO:0034968  

PANTHER

PTHR46307:SF1   PTHR46307:SF2  

Subcellular location

Chromosome  
Nucleus  

Length:

512

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00634999999999999

Exp number, first 60 AAs:

0.00078

Total prob of N-in:

0.00272

outside

1  -  512

 

 

Pi

322.939527

Theta

18.716494

Tajima's D

2.447247

CLR

0.570152

CSRT

0.942752862356882

Interpretation

Uncertain