Gene

KWMTBOMO08628  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007957

Annotation

PREDICTED:_innexin_inx1_[Papilio_xuthus]

Location

Bomo_Chr15(-):1276428-1328593      View in EpiBrowser

Full name

Innexin       + More
Innexin inx1      

Alternative Name

G-Inx1
Protein optic ganglion reduced

Location in the cell

PlasmaMembrane   Reliability : 4.311

CDS

ATGTTTCAATTATTAGGTGGATTGAGGGTGTATTTCCAGTACCAACCGATAAGGACTGACAATGCCGTGTTCAGACTGCACAATGTGTTCACAACGGTGTTATTACTGACGTGCTCAATGATAATTACCGCATCGCAGTACGTAGGAAAGCCTATAATGTGTATCGTTAATGGAATACCGGCGAATGTGGTCAATACGTTCTGTTGGATCACGTCAACGTTCACAATGCCAGATGCTTTCGCAAGAGAGGTCGGTAAAGAAGTAGCGCATCCAGGAGTCGGACCAGAATTTGAAGGAACGGAGAAGAAATACTATACCTACTATCAGTGGGTTTGTTTCGTATTGTTTTTTCAGGCAATAATGTGCTACACGCCCAAGTTTCTATGGGACGCATTCGAAGGTGGGCTGCTCAGGACCATCGTGATGGGACTCAACATCGGGGTTTGCCACCAAGATGAGAAGGAAAAGAAGAAAGACGTCATCATTGATTATCTCCTTCGGCACGAGAGAACGCACAAGCTGTACGCCTTCCGTTATTGGGGCTGCGAGTTACTATGTCTCGTGAATATCATTCTGCAAATGTGGATGATGGATAACTTCTTCAACGGGGAGTTTATGTCGTACGGCACCAGGGTTTTGGGGTACAGCGAAGTCCCGCAGGAAGAAAGATACGATCCGATGATATACGTGTTCCCTCGCATGACTAAATGCACGTTTCACAAGTTCGGCGCGTCCGGCAGCATACAGACCCACGACAGTCTCTGCGTCCTCCCGCTGAACATCGTCAACGAGAAGACGTACATCTTCCTCTGGTTCTGGTACATCATATTGGCGGTCGTTCTCACTCTGCTCGTCATGTACAGACTGGTCATAATCTTCATGCCGGCGGTGAGGCCACGGTTGCTGCACGCGAGGTCCCGGACCTTGTCTCTGGAGACGGCGGTGGCGGTCTCGCGCCGGACCGACCTGGGAGACTGGTGGCTGCTGTACATGCTCGCCAGGAACATGGACCCTCTCATATACAGGGAGCTGATGATAGACTTAGTTAAGCGTATGGGAGAGAAGATCCCGCCCAGGGCGTGA

Protein

MFQLLGGLRVYFQYQPIRTDNAVFRLHNVFTTVLLLTCSMIITASQYVGKPIMCIVNGIPANVVNTFCWITSTFTMPDAFAREVGKEVAHPGVGPEFEGTEKKYYTYYQWVCFVLFFQAIMCYTPKFLWDAFEGGLLRTIVMGLNIGVCHQDEKEKKKDVIIDYLLRHERTHKLYAFRYWGCELLCLVNIILQMWMMDNFFNGEFMSYGTRVLGYSEVPQEERYDPMIYVFPRMTKCTFHKFGASGSIQTHDSLCVLPLNIVNEKTYIFLWFWYIILAVVLTLLVMYRLVIIFMPAVRPRLLHARSRTLSLETAVAVSRRTDLGDWWLLYMLARNMDPLIYRELMIDLVKRMGEKIPPRA

Description

Structural component of the gap junctions.
Structural component of the gap junctions. Essential for generation and/or maintenance of postembryonic neuroblasts and normal development of optic lobe.

Subunit

Heterooligomer of Inx2 and ogre.

Similarity

Belongs to the pannexin family.

Keywords

Cell junction   Cell membrane   Gap junction   Ion channel   Ion transport   Membrane   Transmembrane   Transmembrane helix   Transport   Complete proteome   Reference proteome  

Feature

chain  Innexin inx1

Uniprot

A0A0N1IGD1   A0A3S2TU18   U5EL41   A0A1L8E348   A0A0P6IVV2   A0A2J7PHA0   + More
T1HJJ5   A0A0A1X6Z5   A0A084VW22   A0A0K8WF36   A0A034VHJ6   A0A336LNF3   C0KLS5   Q9XYN0   B4L562   A0A336LJ58   W8AKP4   A0A1A9WPJ9   A0A1A9ZE51   B4NEF7   E0VDS2   A0A1W4V9P3   A0A182XA18   A0A1A9XRV4   B4JMS8   B4M9W5   A0A182PH10   A0A182IN27   Q7PXM2   B3MQ08   A0A182YBA5   A0A1B6IPY0   A0A1I8PFK2   A0A182N9Z6   A0A182QL68   A0A0L0BUD2   A0A1B6EIJ8   A0A023F3Q9   A0A1I8MU37   A0A3B0KJQ3   B4H2D0   B5DN41   A0A0M4F8E4   A0A069DTI2   J3JTV6   A0A182VI05   D6X4I5   A0A1Q3G4K1   B3NXY0   B4Q1D0   A0A1B6LYM0   M9PGW0   P27716   A0A023EQQ4   A0A182R519   Q16FA3   A0A146LXY8   B4R5W1   B4IHI3   A0A1S4EB89   A0A182HKZ7   A0A182MSU0   A0A1Y1MWX4   A0A182K2G6   A0A182U9B5   A0A182VWC7   A0A151XAZ3   A0A0C9QAE6   A0A195EQJ9   A0A195BSP5   A0A158NQK4   A0A195DHW7   A0A2M4BRG2   F4WKA0   A0A2M4BRZ0   A0A2M4ATK9   T1DLK9   A0A2M3ZHP7   W5JC70   A0A1J1HXG5   A0A154NVS6   A0A224XFL2   A0A026WVZ4   E1ZXF1   A0A0L7R3B7   K7J6Q8   A0A1B6D2L4   A0A0J7KSE9   E9HSG3   A0A1B6GPQ2   A0A0N8DXA0   A0A0P5XV35   A0A0N8DHT2   A0A0P6JYZ3   A0A226EKK7   A0A1B6FA42   A0A075M4C0   E2BMI3   A0A2S2Q4I0   A0A0P6EY65  

Pubmed

26354079    25830018    24438588    25348373    10079517    17994087    + More
24495485    20566863    12364791    14747013    17210077    25244985    26108605    25474469    25315136    15632085    23185243    26334808    22516182    23537049    18362917    19820115    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    1963867    11960713    15047872    19038051    24945155    17510324    25585357    26823975    28004739    21347285    21719571    20920257    23761445    24508170    20798317    20075255    21292972   

EMBL

KQ460497    KPJ14317.1    RSAL01000001    RVE55227.1    GANO01001586    JAB58285.1    + More
GFDF01000921    JAV13163.1    GDIQ01003935    JAN90802.1    NEVH01025142    PNF15717.1    ACPB03007073    ACPB03007074    GBXI01017279    GBXI01007777    JAC97012.1    JAD06515.1    ATLV01017404    KE525167    KFB42166.1    GDHF01002844    JAI49470.1    GAKP01017914    JAC41038.1    UFQT01000021    SSX17917.1    FJ619502    ACN41953.1    AF115853    CH933811    EDW06321.1    SSX17916.1    GAMC01021278    GAMC01021277    JAB85278.1    CH964239    EDW82126.1    AAZO01001461    DS235084    EEB11528.1    CH916371    EDV92021.1    CH940655    EDW66024.1    AAAB01008987    EAA00881.3    CH902621    EDV44434.1    GECU01018714    GECU01005274    JAS88992.1    JAT02433.1    AXCN02001521    JRES01001325    KNC23631.1    GECZ01032047    JAS37722.1    GBBI01002701    JAC16011.1    OUUW01000016    SPP88800.1    CH479204    EDW30497.1    CH379064    EDY72848.1    CP012528    ALC48257.1    GBGD01001907    JAC86982.1    APGK01048500    BT126665    KB741112    KB632184    AEE61628.1    ENN73825.1    ERL89625.1    KQ971380    EEZ97264.1    GFDL01000322    JAV34723.1    CH954180    EDV47431.1    CM000162    EDX02419.1    GEBQ01011273    JAT28704.1    AE014298    AGB95145.1    X61180    BT004911    GAPW01002160    JAC11438.1    KJ736822    CH478475    AIF75094.1    EAT32914.1    GDHC01006155    JAQ12474.1    CM000366    EDX17297.1    CH480839    EDW49334.1    APCN01000876    AXCM01008204    GEZM01021245    JAV89060.1    KQ982335    KYQ57517.1    GBYB01000189    JAG69956.1    KQ982021    KYN30555.1    KQ976419    KYM89302.1    ADTU01023366    KQ980824    KYN12490.1    GGFJ01006536    MBW55677.1    GL888199    EGI65324.1    GGFJ01006612    MBW55753.1    GGFK01010799    MBW44120.1    GAMD01000386    JAB01205.1    GGFM01007234    MBW27985.1    ADMH02001846    ETN60918.1    CVRI01000024    CRK92218.1    KQ434769    KZC03795.1    GFTR01005171    JAW11255.1    KK107087    EZA59866.1    GL435038    EFN74128.1    KQ414663    KOC65365.1    AAZX01009384    GEDC01017380    GEDC01012660    JAS19918.1    JAS24638.1    LBMM01003687    KMQ93236.1    GL732751    EFX65318.1    GECZ01005436    JAS64333.1    GDIP01142609    GDIQ01082868    LRGB01000024    JAL61105.1    JAN11869.1    KZS21637.1    GDIP01068910    JAM34805.1    GDIP01032391    JAM71324.1    GDIQ01002736    JAN92001.1    LNIX01000003    OXA57281.1    GECZ01022669    JAS47100.1    KJ736823    AIF75095.1    GL449233    EFN83092.1    GGMS01003308    MBY72511.1    GDIQ01055925    JAN38812.1   

Proteomes

UP000053240    UP000283053    UP000235965    UP000015103    UP000030765    UP000009192    + More
UP000091820    UP000092445    UP000007798    UP000009046    UP000192221    UP000076407    UP000092443    UP000001070    UP000008792    UP000075885    UP000075880    UP000007062    UP000007801    UP000076408    UP000095300    UP000075884    UP000075886    UP000037069    UP000095301    UP000268350    UP000008744    UP000001819    UP000092553    UP000019118    UP000030742    UP000075903    UP000007266    UP000008711    UP000002282    UP000000803    UP000075900    UP000008820    UP000000304    UP000001292    UP000079169    UP000075840    UP000075883    UP000075881    UP000075902    UP000075920    UP000075809    UP000078541    UP000078540    UP000005205    UP000078492    UP000007755    UP000000673    UP000183832    UP000076502    UP000053097    UP000000311    UP000053825    UP000002358    UP000036403    UP000000305    UP000076858    UP000198287    UP000008237   

PRIDE

Q9XYN0    M9PGW0    P27716   

Pfam

PF00876   Innexin

Interpro

IPR000990   Innexin       

ProteinModelPortal

A0A0N1IGD1   A0A3S2TU18   U5EL41   A0A1L8E348   A0A0P6IVV2   A0A2J7PHA0   + More
T1HJJ5   A0A0A1X6Z5   A0A084VW22   A0A0K8WF36   A0A034VHJ6   A0A336LNF3   C0KLS5   Q9XYN0   B4L562   A0A336LJ58   W8AKP4   A0A1A9WPJ9   A0A1A9ZE51   B4NEF7   E0VDS2   A0A1W4V9P3   A0A182XA18   A0A1A9XRV4   B4JMS8   B4M9W5   A0A182PH10   A0A182IN27   Q7PXM2   B3MQ08   A0A182YBA5   A0A1B6IPY0   A0A1I8PFK2   A0A182N9Z6   A0A182QL68   A0A0L0BUD2   A0A1B6EIJ8   A0A023F3Q9   A0A1I8MU37   A0A3B0KJQ3   B4H2D0   B5DN41   A0A0M4F8E4   A0A069DTI2   J3JTV6   A0A182VI05   D6X4I5   A0A1Q3G4K1   B3NXY0   B4Q1D0   A0A1B6LYM0   M9PGW0   P27716   A0A023EQQ4   A0A182R519   Q16FA3   A0A146LXY8   B4R5W1   B4IHI3   A0A1S4EB89   A0A182HKZ7   A0A182MSU0   A0A1Y1MWX4   A0A182K2G6   A0A182U9B5   A0A182VWC7   A0A151XAZ3   A0A0C9QAE6   A0A195EQJ9   A0A195BSP5   A0A158NQK4   A0A195DHW7   A0A2M4BRG2   F4WKA0   A0A2M4BRZ0   A0A2M4ATK9   T1DLK9   A0A2M3ZHP7   W5JC70   A0A1J1HXG5   A0A154NVS6   A0A224XFL2   A0A026WVZ4   E1ZXF1   A0A0L7R3B7   K7J6Q8   A0A1B6D2L4   A0A0J7KSE9   E9HSG3   A0A1B6GPQ2   A0A0N8DXA0   A0A0P5XV35   A0A0N8DHT2   A0A0P6JYZ3   A0A226EKK7   A0A1B6FA42   A0A075M4C0   E2BMI3   A0A2S2Q4I0   A0A0P6EY65  

PDB

5H1R     E-value=1.97026e-16,     Score=209

KEGG

101744232    K22037 innexin | (RefSeq) innexin inx1

GO

GO:0016021   GO:0006811   GO:0005921   GO:0005886   GO:0005243   GO:0007603   GO:0016323   GO:0010496   GO:0007602   GO:0007632   GO:0006355   GO:0043565   GO:0005057   GO:0007165   GO:0016620   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR11893  

Subcellular location

Cell membrane  
Cell junction  
Gap junction  
Basolateral cell membrane  

Length:

360

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

100.33281

Exp number, first 60 AAs:

25.4506

Total prob of N-in:

0.57456

POSSIBLE N-term signal

sequence

inside

1  -  20

TMhelix

21  -  43

outside

44  -  106

TMhelix

107  -  129

inside

130  -  173

TMhelix

174  -  196

outside

197  -  268

TMhelix

269  -  291

inside

292  -  360

 

 

Pi

24.25257

Theta

17.356018

Tajima's D

0.705724

CLR

0.228477

CSRT

0.585020748962552

Interpretation

Uncertain