Gene

KWMTBOMO08624

Pre Gene Modal

BGIBMGA007626

Annotation

PREDICTED:_innexin_shaking-B_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(+):1194794-1222326      View in EpiBrowser

Full name

Innexin       + More
Innexin shaking-B      

Alternative Name

Protein passover

Location in the cell

PlasmaMembrane   Reliability : 3.988

CDS

ATGTTAGACGTATTCCGCGGTTTGAAGAATCTAATTAAGGTGAACTATGTGCATATCGACTCGCCTGTATTCCGGTTGCATTACTCGATCACGGTCATCCTGCTGATATCGTTCAGTCTCATTGTGACCACGCGCCAGTACGTCGGGAACCCCATAGACTGTATCCACACCAAGGACATCCCAGAGGACGTTCTGAACACGTACTGCTGGATACATTCGACATACACCCTCAAGAGCTACTTCGAGAAGACGGTGGGCGTCGAGGTGCCGTACCCTGGGATAGGGAACAGCAGGGAGAAGGGCAAGGAAGATATGAGCGACAGGAAAGTCTACAAGTACTACCAATGGGTCTGCTTCTGTCTTTTTTTTCAGGCAATGCTGTTCTACGCCCCGCGGTGGCTGTGGAAATCTTGGGAGGGCGGCAAGATCCGCGCCCTCATGATGGACCTAGACGTCGCAGTCTGCACGGAGATAGAGAAGAAGACAAAAAAGAAACTAATCCTGGACTATCTGTGGGAAAACCTGAGGTACCACAACTGGTGGGCCTACAGGTACTACCTGTGCGAAGCGCTTGCCCTTGTCAATGTTATAGGGCAAATGTTCTTGATGAACAGGTTCTTCGACGGAGAGTTTATGACCTTCGGGCTGAAGGTGATCAAGTACATGGAGTCCGACCAGGAGATACGAATCGACCCCATGATATACATATTTCCAAGGATGGTGAAGTGTACGCTTTTCAACAAATTCGGTTCATCCGGCGAGGTGGAGCGGCACGACGCGCTCTGCATCTTGCCCCTGAACGTAGTCAACGAGAAGATCTACATCTTCCTCTGGTTCTGGTTCGTCATCCTCGGCTTCCTTACTTTCATCACGCTCATCTACAGGATCATCATCATCTTCTCGCCGCGCATGCGCGTCTACATGATGCGAATGAGGTTCCGACTCGTGAGGCGGGACAATATCGACACCATAGTGAGGAGAAGCAAGATGGGAGACTGGTATCTGCTCTACATACTAGGAGAGAACCTCGACTCGATCATCTTCAGGGATATAATGCAGGAGTTCGCGAACAAGCTGAACCACAACTACCAGCACCACATTCACGGCGTCCCGGACGCGTGA

Protein

MLDVFRGLKNLIKVNYVHIDSPVFRLHYSITVILLISFSLIVTTRQYVGNPIDCIHTKDIPEDVLNTYCWIHSTYTLKSYFEKTVGVEVPYPGIGNSREKGKEDMSDRKVYKYYQWVCFCLFFQAMLFYAPRWLWKSWEGGKIRALMMDLDVAVCTEIEKKTKKKLILDYLWENLRYHNWWAYRYYLCEALALVNVIGQMFLMNRFFDGEFMTFGLKVIKYMESDQEIRIDPMIYIFPRMVKCTLFNKFGSSGEVERHDALCILPLNVVNEKIYIFLWFWFVILGFLTFITLIYRIIIIFSPRMRVYMMRMRFRLVRRDNIDTIVRRSKMGDWYLLYILGENLDSIIFRDIMQEFANKLNHNYQHHIHGVPDA

Description

Structural component of the gap junctions.
Structural component of the gap junctions at electrical synapses in distal and mid-depth levels in the lamina.
Structural component of the gap junctions at electrical synapses in distal and mid-depth levels in the lamina. Isoform Lethal forms voltage sensitive intercellular channels through homotypic interactions.

Subunit

Monomer.
Monomer (isoform Lethal).

Similarity

Belongs to the pannexin family.

Keywords

Cell junction   Cell membrane   Complete proteome   Gap junction   Ion channel   Ion transport   Membrane   Reference proteome   Transmembrane   Transmembrane helix   Transport   Alternative splicing   Behavior  

Feature

chain  Innexin shaking-B
splice variant  In isoform E.

Uniprot

A0A0N1IHM3   A0A437BXR1   A0A2A4K6A3   A0A194PPI7   A0A212EW68   A0A336LII3   + More
A0A1I8PXW4   A0A182YB94   B4JXM9   B5DNE9   B4M3P9   B4L370   B4PYJ7   B4I6B1   B3NY39   Q1DH70   A0A1W4VVW7   B0XHF1   P33085   A0A2C9GPG3   A0A182L9C6   Q7PXN1   B4MSW8   A0A0A1XT70   A0A0K8WG78   A0A034WH33   W8B2W5   A0A1J1HVY9   A0A195ERQ0   A0A026WUY9   A0A1B6EBL0   A0A158NQK3   A0A0C9QHU7   A0A1W4XQJ8   J9JSD1   A0A2H8TIN1   A0A2S2PYJ4   A0A1Y1M793   K7J6Q6   B3N0Z8   A0A1B6G3H6   A0A1B6HU79   D6X4I2   E0VDS4   T1HVH6   E9G961   A0A1B6MLB6   A0A1I8PXX3   C0KLS8   N6U651   A0A0L0BU34   A0A1I8PXU9   A0A0Q9WMJ0   A0A0Q9WMI1   A0A0R3P0T5   A0A0Q9WDL3   A0A0Q9WM73   A0A3B0K1Z9   A0A3B0K037   A0A0R3P0X1   A0A1I8PXY8   A0A0R3P668   A0A0R1EC29   A0A0Q5T681   P33085-4   M9NGR8   A0A1B0GAK5   P33085-2   A0A1W4VIF9   G4LU30   A0A0K8U1E9   A0A195D3W6   A0A1W7R8S4   F5HMP1   A0A336LJS9   A0A0R3P573   A0A0Q9WP89   A0A226EJ08   A0A3R7N7V3   A0A068BKA8   A0A146LYX0   A0A097KUR2   A0A0K2V323   A0A1D2N4L7   A0A0A9X0I9   A0A2J7PH97   A0A2P6L614   A0A0J7KZE2   A0A3L8E3W4   A0A023F430   A0A154NVX6   A0A195BQZ2   F4WKA1   A0A088A2D6   T1JJS6   A0A0L7R3P8   A0A0Q5TJ67   A0A2A3EBF3   A0A131XRY4   E1ZXF2  

Pubmed

26354079    22118469    25244985    17994087    15632085    17550304    + More
17510324    1487155    8500183    7601305    7892218    10731132    12537572    9552170    9428764    10440730    20966253    12364791    25830018    25348373    24495485    24508170    21347285    28004739    20075255    18362917    19820115    20566863    21292972    23537049    26108605    18057021    23185243    12537568    12537573    12537574    16110336    17569856    17569867    26109357    26109356    14747013    17210077    26823975    25210156    27289101    25401762    30249741    25474469    21719571    20798317   

EMBL

KQ460497    KPJ14316.1    RSAL01000001    RVE55228.1    NWSH01000135    PCG79200.1    + More
KQ459596    KPI95356.1    AGBW02012071    OWR45726.1    UFQT01000021    SSX17914.1    CH916376    EDV95128.1    CH379064    EDY72957.1    CH940651    EDW65424.1    CH933810    EDW06998.1    CM000162    EDX03038.1    CH480823    EDW56317.1    CH954180    EDV47560.1    CH899795    EAT32503.1    DS233153    EDS28380.1    M98872    X65103    L13306    S78495    U17330    AE014298    BT025062    APCN01000876    AAAB01008987    EAA00824.1    CH963851    EDW75207.1    GBXI01000142    JAD14150.1    GDHF01002146    JAI50168.1    GAKP01005884    JAC53068.1    GAMC01018964    JAB87591.1    CVRI01000024    CRK92232.1    KQ982021    KYN30554.1    KK107087    EZA59865.1    GEDC01001987    JAS35311.1    ADTU01023365    ADTU01023366    GBYB01000132    JAG69899.1    ABLF02036239    GFXV01001323    MBW13128.1    GGMS01001412    MBY70615.1    GEZM01043354    JAV79177.1    AAZX01003113    CH902650    EDV30033.2    GECZ01012779    JAS56990.1    GECU01029505    GECU01007631    JAS78201.1    JAT00076.1    KQ971380    EEZ97266.1    AAZO01001464    DS235084    EEB11530.1    ACPB03015783    GL732535    EFX84089.1    GEBQ01003273    JAT36704.1    FJ619505    ACN41956.1    APGK01041017    KB740987    KB631964    ENN76126.1    ERL87521.1    JRES01001334    KNC23590.1    KRF93903.1    KRF82228.1    KRT06878.1    KRF82230.1    KRF93906.1    OUUW01000011    SPP86692.1    SPP86693.1    KRT06881.1    KRT06880.1    KRK07080.1    KQS30559.1    AFH07500.1    CCAG010019535    CCAG010019536    CCAG010019537    CCAG010019538    CCAG010019539    CCAG010019540    CCAG010019541    BT132660    AEQ05562.1    GDHF01032154    JAI20160.1    KQ976885    KYN07541.1    GEHC01000103    JAV47542.1    EGK97563.1    SSX17915.1    KRT06879.1    KRF82229.1    LNIX01000003    OXA57280.1    QCYY01001224    ROT79567.1    KJ642222    AID07491.1    GDHC01005838    JAQ12791.1    KM984501    AIT97136.1    HACA01027523    CDW44884.1    LJIJ01000239    ODN00005.1    GBHO01031301    JAG12303.1    NEVH01025142    PNF15698.1    MWRG01001558    PRD34022.1    LBMM01001661    KMQ95927.1    QOIP01000001    RLU26919.1    GBBI01002467    JAC16245.1    KQ434769    KZC03797.1    KQ976419    KYM89303.1    GL888199    EGI65325.1    JH431978    KQ414663    KOC65366.1    KQS30558.1    KZ288311    PBC28516.1    GEFM01006818    JAP68978.1    GL435038    EFN74129.1   

Proteomes

UP000053240    UP000283053    UP000218220    UP000053268    UP000007151    UP000095300    + More
UP000076408    UP000001070    UP000001819    UP000008792    UP000009192    UP000002282    UP000001292    UP000008711    UP000008820    UP000192221    UP000002320    UP000000803    UP000075840    UP000075882    UP000007062    UP000007798    UP000183832    UP000078541    UP000053097    UP000005205    UP000192223    UP000007819    UP000002358    UP000007801    UP000007266    UP000009046    UP000015103    UP000000305    UP000019118    UP000030742    UP000037069    UP000268350    UP000092444    UP000078542    UP000198287    UP000283509    UP000094527    UP000235965    UP000036403    UP000279307    UP000076502    UP000078540    UP000007755    UP000005203    UP000053825    UP000242457    UP000000311   

PRIDE

P33085    M9NGR8    G4LU30   

Pfam

PF00876   Innexin

Interpro

IPR000990   Innexin       

ProteinModelPortal

A0A0N1IHM3   A0A437BXR1   A0A2A4K6A3   A0A194PPI7   A0A212EW68   A0A336LII3   + More
A0A1I8PXW4   A0A182YB94   B4JXM9   B5DNE9   B4M3P9   B4L370   B4PYJ7   B4I6B1   B3NY39   Q1DH70   A0A1W4VVW7   B0XHF1   P33085   A0A2C9GPG3   A0A182L9C6   Q7PXN1   B4MSW8   A0A0A1XT70   A0A0K8WG78   A0A034WH33   W8B2W5   A0A1J1HVY9   A0A195ERQ0   A0A026WUY9   A0A1B6EBL0   A0A158NQK3   A0A0C9QHU7   A0A1W4XQJ8   J9JSD1   A0A2H8TIN1   A0A2S2PYJ4   A0A1Y1M793   K7J6Q6   B3N0Z8   A0A1B6G3H6   A0A1B6HU79   D6X4I2   E0VDS4   T1HVH6   E9G961   A0A1B6MLB6   A0A1I8PXX3   C0KLS8   N6U651   A0A0L0BU34   A0A1I8PXU9   A0A0Q9WMJ0   A0A0Q9WMI1   A0A0R3P0T5   A0A0Q9WDL3   A0A0Q9WM73   A0A3B0K1Z9   A0A3B0K037   A0A0R3P0X1   A0A1I8PXY8   A0A0R3P668   A0A0R1EC29   A0A0Q5T681   P33085-4   M9NGR8   A0A1B0GAK5   P33085-2   A0A1W4VIF9   G4LU30   A0A0K8U1E9   A0A195D3W6   A0A1W7R8S4   F5HMP1   A0A336LJS9   A0A0R3P573   A0A0Q9WP89   A0A226EJ08   A0A3R7N7V3   A0A068BKA8   A0A146LYX0   A0A097KUR2   A0A0K2V323   A0A1D2N4L7   A0A0A9X0I9   A0A2J7PH97   A0A2P6L614   A0A0J7KZE2   A0A3L8E3W4   A0A023F430   A0A154NVX6   A0A195BQZ2   F4WKA1   A0A088A2D6   T1JJS6   A0A0L7R3P8   A0A0Q5TJ67   A0A2A3EBF3   A0A131XRY4   E1ZXF2  

PDB

5H1R     E-value=2.72314e-15,     Score=199

KEGG

101744516    K22037 innexin | (RefSeq) innexin shaking-B

GO

GO:0016021   GO:0006811   GO:0005921   GO:0005886   GO:0016264   GO:0009881   GO:0005243   GO:0009416   GO:0003254   GO:0007602   GO:0010644   GO:0007630   GO:0055085   GO:0010496   GO:0006355   GO:0043565   GO:0005057   GO:0007165   GO:0016620   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR11893  

Subcellular location

Cell membrane  
Cell junction  
Gap junction  

Length:

373

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

89.53429

Exp number, first 60 AAs:

21.49817

Total prob of N-in:

0.74194

POSSIBLE N-term signal

sequence

inside

1  -  20

TMhelix

21  -  43

outside

44  -  112

TMhelix

113  -  135

inside

136  -  179

TMhelix

180  -  202

outside

203  -  276

TMhelix

277  -  299

inside

300  -  373

 

 

Pi

249.759991

Theta

174.523726

Tajima's D

0.682071

CLR

0.709081

CSRT

0.567571621418929

Interpretation

Uncertain