Gene

KWMTBOMO08578  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007601

Annotation

PREDICTED:_delta-1-pyrroline-5-carboxylate_dehydrogenase?_mitochondrial_[Papilio_xuthus]

Location

Bomo_Chr15(+):269798-272046      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 2.824

CDS

ATGCTTACAATCTGGGCGAGAATCGGTCGCGTACGTTCGCTAGAGCGAACGTTGTCTAGCGTCGTAGACTTGCCGCAATTTCAGGATGGGAGCATCCATAACGAGCCTGTGTTGGGTTATCGTGCCGGAAGCCGGGAACGCCAAGACCTAATTGAGGAGCTGAAACGAACCGCTTCAGTAATTGAAGACGTACCAATTGTAATTGCCGGAAAAAATATTACAGAAGGCGAGCCACGATATCAGGTGATGCCCCATGATCACTCAAAAAAGATAGCTAAATATTACTATGCCAGTGAAAAAACAATTGAAAAGGCGATTCAAGCGTCTGTCGATGCTCAAACTCGTTGGGACCGCACTCCGCTGACTGAACGCGTAAAAATCTGGCAGACAGCAGCTGAGCTAATGGCCGGTGCGTATCGACAGAGCCTCAATGCTGCGACCATACTTGGACAGTCGAAATCAGTAATTCAAGCTGAAATTGATGCTGCAGCTGAACTTATTGATTTTTTCCGTTTTAATGTACACTTCCTGAAGGAAAATTCAAAATATCAACCTATTTCTGAGAGTCCCACAATAACCAAAAACTCTTTGAGATTTCGTGGCATAGATGGATTTATTGCAGCAATAAGTCCCTTCAATTTCACTGCCATTGGAGGCAACCTCGCATACACACCTGCACTTATGGGCAATGCAGTGTTATGGAAACCATCGGATACAGCTTTGTTGTCCAACTGGCGAATCTTCAATATTATGAGGGAAGCTGGTCTTCCAGATGGTGTTGTAAACTTTGTTCCATCCGATGGTCCTACATTTGGTCGAGTCATCACATCATCACCATACCTGGCTGGAATCAACTTCACAGGCTCTGTGCCCACTTTTAACTGGCTGTGGAATGAAGTAGGCAAGAATCTTAATACATATCGTAACTATCCCAGACTCATTGGAGAATGTGGAGGAAAGAATTACCACTTTGTACACCCCTCTGCTGATATACAAACTGTGGTTAGTGGCACCATCCGATCAGCATTTGAATTTTGTGGACAGAAGTGTTCAGCTTGCTCCAGAATATATATCCCTCAGTCTCTGTATGAACCAATTAAGACAGGATTACTTGCAGAAAGAGCTAAACTGAAGATTGGTGACCCTGCAGACTTTTCAGTGTTCACAGCGGCTGTCATTGATGACAAAGCTTTTGCTAGGATCACAGGATACATCCAAAGAGCCAAGAAGAATCCTAAGAACAAGATCTTGGGAGGTGGTGAGTTTGACAATAGCAAGGGCTACTTTGTGCAGCCTACCATCATTGAGACAACAGATCCGCATGACAAGCTCATGACAGAAGAGATCTTCGGTCCAGTGCTCACCATTTATGTATATAATGATAAAGATATTGATAAAACCATGGATTTAATTGGTACTTCCACAAAATTTGCTCTTACAGGAGCTATATTTGCTAAAGATCAAGTATTTTTGAAAAAAGCATATGAAAATCTCAAAATGACTGCTGGCAACTTCTATATCAATGACAAATCAACTGGATCTGTAGTCGGTCAGCAGCCATTTGGAGGTGGCCGTATGTCAGGTACTAATGACAAGGCAGGTGGTCCCAACTATGTCATGAGGTGGACAACTCCACAATCTATTAAGGAAACATTTGTTCCACTTACTGATATTGATTATCCATATATGAGAGAATGA

Protein

MLTIWARIGRVRSLERTLSSVVDLPQFQDGSIHNEPVLGYRAGSRERQDLIEELKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTPALMGNAVLWKPSDTALLSNWRIFNIMREAGLPDGVVNFVPSDGPTFGRVITSSPYLAGINFTGSVPTFNWLWNEVGKNLNTYRNYPRLIGECGGKNYHFVHPSADIQTVVSGTIRSAFEFCGQKCSACSRIYIPQSLYEPIKTGLLAERAKLKIGDPADFSVFTAAVIDDKAFARITGYIQRAKKNPKNKILGGGEFDNSKGYFVQPTIIETTDPHDKLMTEEIFGPVLTIYVYNDKDIDKTMDLIGTSTKFALTGAIFAKDQVFLKKAYENLKMTAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPNYVMRWTTPQSIKETFVPLTDIDYPYMRE

Similarity

Belongs to the aldehyde dehydrogenase family.

Uniprot

H9JDK4   A0A220K8K2   A0A2W1B9V2   A0A2A4J1B1   A0A0N1IH81   A0A194PPD3   + More
A0A212F5G2   A0A1I8NER1   T1PE86   A0A182UUM8   A0A182XF32   A0A182LNJ8   Q7QA89   A0A182HVK0   A0A182TXD4   A0A182PG78   A0A0L0CEV1   A0A182W346   A0A182R8H8   A0A1I8QA61   A0A182YJQ4   A0A182KFH9   A0A023EU27   A0A0M4F1S2   A0A182H474   A0A2M3Z1V2   A0A182GZF5   A0A182SZD3   A0A182NCR2   A0A2M3Z1W0   A0A2M4BIN8   Q17A27   A0A182LZA6   A0A2M4BIQ5   A0A1J1IF54   A0A2M4A511   U5EY10   D2A4K8   A0A182QCA8   W5J9M2   T1EAL1   A0A182FP42   B0WKF4   A0A0T6BB18   A0A336MR06   B3MAI2   B4PI44   A0A1Q3FN06   A0A1Q3FMV8   A0A1Q3FMZ6   A0A0K8TMU3   A0A182JA00   B4NT61   B4N4H1   B3NJ08   A0A3B0J4I2   A0A1W4UE03   A0A084WQ65   Q9VNX4   B4L001   B4LC03   Q8T3P0   B4IAW9   A0A2P8YI55   N6TIF6   A0A2S2R7G8   A0A1A9XDC2   B4J0R3   Q2M042   B4GS53   A0A2S2PEX9   A0A1L8E0I3   A0A1L8E0C9   A0A067QNY3   A0A2U9K3B6   A0A1A9ZS83   A0A1B0BYU8   A0A1B0GD54   A0A2J7Q9V9   N6TBG3   V5I8H9   A0A1A9UQH1   A0A1B6GJ23   A0A1A9X107   G9FQ75   A0A1I9WLH5   A0A1Y1LI01   A0A0P4VJD2   A0A0C9Q928   A0A026WYS8   A0A1B6DE11   A0A069DVI3   A0A1W4XT86   A0A0J7L715   A0A224XMI1   K7IVK4   E2BU71   A0A232F6H4   A0A2P2HW63   A0A0V0G4C4  

Pubmed

19121390    28630352    28756777    26354079    22118469    25315136    + More
20966253    12364791    14747013    17210077    26108605    25244985    24945155    26483478    17510324    18362917    19820115    20920257    23761445    17994087    17550304    26369729    22936249    18057021    24438588    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    29403074    23537049    15632085    23185243    24845553    27538518    28004739    27129103    24508170    30249741    26334808    20075255    20798317    28648823   

EMBL

BABH01003355    MF319700    ASJ26414.1    KZ150375    PZC71115.1    NWSH01003734    + More
PCG65865.1    KQ459717    KPJ20323.1    KQ459596    KPI95301.1    AGBW02010203    OWR48975.1    KA646994    KA649532    AFP61623.1    AAAB01008898    EAA09247.4    APCN01005788    JRES01000484    KNC30918.1    GAPW01000730    JAC12868.1    CP012525    ALC44945.1    JXUM01108965    JXUM01108966    JXUM01108967    KQ565279    KXJ71135.1    GGFM01001761    MBW22512.1    JXUM01021733    JXUM01021734    JXUM01021735    JXUM01021736    JXUM01021737    KQ560610    KXJ81633.1    GGFM01001742    MBW22493.1    GGFJ01003723    MBW52864.1    CH477340    EAT43137.1    AXCM01007092    GGFJ01003722    MBW52863.1    CVRI01000048    CRK98843.1    GGFK01002552    MBW35873.1    GANO01002252    JAB57619.1    KQ971344    EFA05239.1    AXCN02000334    ADMH02002085    ETN59444.1    GAMD01000943    JAB00648.1    DS231971    EDS29773.1    LJIG01002545    KRT84395.1    UFQT01002045    SSX32510.1    CH902618    EDV41269.1    CM000159    EDW95492.1    KRK02458.1    GFDL01006138    JAV28907.1    GFDL01006114    JAV28931.1    GFDL01006148    JAV28897.1    GDAI01001926    JAI15677.1    CH982756    CM002912    EDX15751.1    KMZ01109.1    CH964095    EDW79045.1    KRF98997.1    CH954178    EDV52725.1    KQS44401.1    OUUW01000002    SPP76415.1    ATLV01025273    KE525379    KFB52359.1    AE014296    BT050518    AAF51790.1    AAN12191.1    AAN12193.1    ACJ13225.1    ADV37595.1    AGB94889.1    CH933809    EDW19036.1    CH940647    EDW69803.1    KRF84586.1    KRF84587.1    KRF84588.1    KRF84589.1    AY094741    AAM11094.1    CH480826    EDW44432.1    PYGN01000578    PSN43931.1    APGK01036620    APGK01036621    KB740941    KB632409    ENN77583.1    ERL95167.1    GGMS01016437    MBY85640.1    CH916366    EDV97918.1    CH379069    EAL31094.1    KRT07862.1    KRT07863.1    CH479188    EDW40588.1    GGMR01015392    MBY28011.1    GFDF01001895    JAV12189.1    GFDF01001894    JAV12190.1    KK853123    KDR11043.1    MF446846    AWS20464.1    JXJN01022837    CCAG010002317    NEVH01016344    PNF25362.1    ENN77584.1    GALX01004655    JAB63811.1    GECZ01007348    JAS62421.1    JN187429    AET80385.2    KU932359    APA33995.1    GEZM01060188    JAV71206.1    GDKW01001508    JAI55087.1    GBYB01010783    JAG80550.1    KK107063    QOIP01000005    EZA61200.1    RLU22531.1    GEDC01013426    JAS23872.1    GBGD01000999    JAC87890.1    LBMM01000397    KMQ98458.1    GFTR01007205    JAW09221.1    GL450586    EFN80755.1    NNAY01000799    OXU26444.1    IACF01000224    LAB66023.1    GECL01003230    JAP02894.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000095301    + More
UP000075903    UP000076407    UP000075882    UP000007062    UP000075840    UP000075902    UP000075885    UP000037069    UP000075920    UP000075900    UP000095300    UP000076408    UP000075881    UP000092553    UP000069940    UP000249989    UP000075901    UP000075884    UP000008820    UP000075883    UP000183832    UP000007266    UP000075886    UP000000673    UP000069272    UP000002320    UP000007801    UP000002282    UP000075880    UP000000304    UP000007798    UP000008711    UP000268350    UP000192221    UP000030765    UP000000803    UP000009192    UP000008792    UP000001292    UP000245037    UP000019118    UP000030742    UP000092443    UP000001070    UP000001819    UP000008744    UP000027135    UP000092445    UP000092460    UP000092444    UP000235965    UP000078200    UP000091820    UP000053097    UP000279307    UP000192223    UP000036403    UP000002358    UP000008237    UP000215335   

PRIDE

H9JDK4    Q9VNX4    Q8T3P0   

Pfam

PF00171   Aldedh        + More
PF04055   Radical_SAM
PF01846   FF
PF00397   WW
PF00919   UPF0004

Interpro

IPR016161   Ald_DH/histidinol_DH        + More
IPR016163   Ald_DH_C       
IPR016160   Ald_DH_CS_CYS       
IPR005931   P5CDH/ALDH4A1       
IPR016162   Ald_DH_N       
IPR015590   Aldehyde_DH_dom       
IPR029510   Ald_DH_CS_GLU       
IPR036517   FF_domain_sf       
IPR006638   Elp3/MiaB/NifB       
IPR002713   FF_domain       
IPR006463   MiaB_methiolase       
IPR005839   Methylthiotransferase       
IPR001202   WW_dom       
IPR023404   rSAM_horseshoe       
IPR013848   Methylthiotransferase_N       
IPR020612   Methylthiotransferase_CS       
IPR038135   Methylthiotransferase_N_sf       
IPR036020   WW_dom_sf       
IPR007197   rSAM       

SUPFAM

SSF53720   SSF53720        + More
SSF81698   SSF81698       
SSF51045   SSF51045       

Gene 3D

3.40.309.10     3.40.605.10     1.10.10.440     3.40.50.12160     3.80.30.20    

CDD

cd07123  ALDH_F4-17_P5CDH
cd00201  WW

ProteinModelPortal

H9JDK4   A0A220K8K2   A0A2W1B9V2   A0A2A4J1B1   A0A0N1IH81   A0A194PPD3   + More
A0A212F5G2   A0A1I8NER1   T1PE86   A0A182UUM8   A0A182XF32   A0A182LNJ8   Q7QA89   A0A182HVK0   A0A182TXD4   A0A182PG78   A0A0L0CEV1   A0A182W346   A0A182R8H8   A0A1I8QA61   A0A182YJQ4   A0A182KFH9   A0A023EU27   A0A0M4F1S2   A0A182H474   A0A2M3Z1V2   A0A182GZF5   A0A182SZD3   A0A182NCR2   A0A2M3Z1W0   A0A2M4BIN8   Q17A27   A0A182LZA6   A0A2M4BIQ5   A0A1J1IF54   A0A2M4A511   U5EY10   D2A4K8   A0A182QCA8   W5J9M2   T1EAL1   A0A182FP42   B0WKF4   A0A0T6BB18   A0A336MR06   B3MAI2   B4PI44   A0A1Q3FN06   A0A1Q3FMV8   A0A1Q3FMZ6   A0A0K8TMU3   A0A182JA00   B4NT61   B4N4H1   B3NJ08   A0A3B0J4I2   A0A1W4UE03   A0A084WQ65   Q9VNX4   B4L001   B4LC03   Q8T3P0   B4IAW9   A0A2P8YI55   N6TIF6   A0A2S2R7G8   A0A1A9XDC2   B4J0R3   Q2M042   B4GS53   A0A2S2PEX9   A0A1L8E0I3   A0A1L8E0C9   A0A067QNY3   A0A2U9K3B6   A0A1A9ZS83   A0A1B0BYU8   A0A1B0GD54   A0A2J7Q9V9   N6TBG3   V5I8H9   A0A1A9UQH1   A0A1B6GJ23   A0A1A9X107   G9FQ75   A0A1I9WLH5   A0A1Y1LI01   A0A0P4VJD2   A0A0C9Q928   A0A026WYS8   A0A1B6DE11   A0A069DVI3   A0A1W4XT86   A0A0J7L715   A0A224XMI1   K7IVK4   E2BU71   A0A232F6H4   A0A2P2HW63   A0A0V0G4C4  

PDB

4LH3     E-value=6.09674e-180,     Score=1621

KEGG

101741966    K00294 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] | (RefSeq) delta-1-pyrroline-5-carboxyl

PATHWAY

00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00330    Arginine and proline metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003842   GO:0016620   GO:0010133   GO:0006560   GO:0005759   GO:0005739   GO:0007005   GO:0045292   GO:0006400   GO:0016740   GO:0051539   GO:0006537   GO:0006561   GO:0008152   GO:0016491   GO:0006418   GO:0003676   GO:0016876   GO:0043039   GO:0055114  

Length:

565

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.43137000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.13732

outside

1  -  565

 

 

Pi

172.045747

Theta

198.413366

Tajima's D

-0.309515

CLR

0.058655

CSRT

0.291385430728464

Interpretation

Uncertain