Gene

KWMTBOMO08572

Pre Gene Modal

BGIBMGA007980

Annotation

FMRFamide_receptor_[Bombyx_mori]

Location

Bomo_Chr15(-):22395-29435      View in EpiBrowser

Full name

FMRFamide receptor      

Location in the cell

PlasmaMembrane   Reliability : 4.87

CDS

ATGAACGGCACCGAGGGGGAGGGGTGCGACTCCGACGTGGGCGTGCAGCCCGCCGACAAGCTGTTCCGCTTCGTGGTGCACGGCGTGCTGCTCAACGCGATCGGCGCTGCCGGCCTACTCGGCAACGCGCTGTCCGTCGTCGTGCTCTCGCGGCCACAGATGCGCTCCTCCATCAACTGTCTGCTGGTGGGGCTCGCCGCCTGCGACACCGTGCTCATCCTCACCTCCGTGCTGCTCTTTGGCCTCACCGCCGTTTACCCGTACACGGGCCGCCTGCGCTACTACTACTACCACGTCTGCCCCCACATCACGCCCTACGCCTACCCCATAGCCAACGCGGCGCAAACCATGTCCGTCTATCTAACGCTGATCGTGACGGTCGAGCGGTGGGTCGCCGTCTGCCATCCGTTCCGCGCCAAGTCGCTGTGCACGTCTTCGCGGGCCCGCTGGTACGTGCTGGGCACGGCCGCCTTCGCGCTCGCCTACAACGCTCCCAAGTTCCTCGAGGCGGAGGTGGTGACGCGCAGCGTGGACGGCGAGCCAGTGTACTGCGTGACGGCTGACCTGCACTTCCGCACCGAGACCTACATCGTGGTGTACATCCACTCCCTGTACATGATCGTGATGTACATCGTGCCGTTCTCTGCGCTGGCGGCGCTGAACGCGTGCATCGTGCGGCAGGTGCGGCGGGCGCAGGCCGAGCGGGCGCGCCTGTCGCGGGTGCAGCGCCGCGAGCTGGGCCTCGCCACCATGCTGCTCGTGGTCGTGCTCGTATTCTTCCTGTGCAACCTGCTGCCGCTCGTCACCAACTCGTTCGAAGTCTTCCTCGGGGACCAGCTAGAAAACTTAGATCCTCTCGTAAAGACGAGCAATCTTCTGGTGACAATCAACAGTAGCGTAAACTTTGTGATTTATGTGATATTTGGGGAGAAATTCAAGCGCGTGTTCCTGAAGATGTTCTGCGCGGGCGGATGGCGGCGGCGGACGCGCGACTCGCCGGAGCAGACGCGCGACGACTCGTTCGCGTCTTGCGGCGAGCGCGTGTCGCTGCGTCTAGTGCGGAACGGCACGCTGCGTCGCTCGGAGCTGCGCGCGCCCCCCCGGGGCCGCAGCCGCCGCGCCCCCTCCCCCTCCGTGTACTACCCCACCCCCCTCACTGACGTCACCAGCGCGCTCTCCGTCTCTGAGCCGCCGCCTGCCGCCATGCGATGGAACGGACACACGCGGTCGCACTTCTAA

Protein

MNGTEGEGCDSDVGVQPADKLFRFVVHGVLLNAIGAAGLLGNALSVVVLSRPQMRSSINCLLVGLAACDTVLILTSVLLFGLTAVYPYTGRLRYYYYHVCPHITPYAYPIANAAQTMSVYLTLIVTVERWVAVCHPFRAKSLCTSSRARWYVLGTAAFALAYNAPKFLEAEVVTRSVDGEPVYCVTADLHFRTETYIVVYIHSLYMIVMYIVPFSALAALNACIVRQVRRAQAERARLSRVQRRELGLATMLLVVVLVFFLCNLLPLVTNSFEVFLGDQLENLDPLVKTSNLLVTINSSVNFVIYVIFGEKFKRVFLKMFCAGGWRRRTRDSPEQTRDDSFASCGERVSLRLVRNGTLRRSELRAPPRGRSRRAPSPSVYYPTPLTDVTSALSVSEPPPAAMRWNGHTRSHF

Description

A receptor for the FMRFamide peptides. Reacts with high affinity to FMRFamide and intrinsic FMRFamide-related peptides.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Keywords

Cell membrane   Complete proteome   G-protein coupled receptor   Glycoprotein   Membrane   Receptor   Reference proteome   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  FMRFamide receptor

Uniprot

H9JEN3   Q1MW82   A0A2H1WR64   A0A2W1BE79   A0A0S1YDJ3   A0A194PVY8   + More
A0A0N0PF39   A0A1J1IA62   A0A2J7RM31   A0A1B0D359   A0A067RIB2   A0A1B0CRX1   D6WCQ8   A0A182V7A9   A0A182PKD3   A0A182U6E5   A0A182KM77   A0A182I0I1   A0A182XBP5   A0A182Q005   Q7PYB7   A0A182YJX1   A0A182N4X7   A0A182VQV3   A0A182RBX4   E0VLX5   A0A182MKG8   Q1EHB5   A0A182H745   A0A084VRS3   A0A1Y1NB30   Q1DGJ7   Q17FI7   A0A182JK10   A0A1S4F4M7   U3U7P6   A0A182F6Y2   B0WKQ9   W5JQB2   A0A1B6M289   A0A1B6GSL8   A0A1B6HDC3   A0A154PN34   B4HTI3   B3M7F9   F4WSQ5   A0A2P8Y9A7   M9PBK3   Q9VZW5   B4QP04   A0A026VZK6   A0A1B0B700   A0A1A9YIC2   B4PCX0   Q29E43   B3NF13   X1WJ26   A0A1B0GFN0   A0A151ISG2   T1HBY9   A0A3B0JAT3   A0A0M5J5H2   F8J1K6   A0A310STP5   A0A151XDB0   E2AA00   A0A1W4VPK2   B4MN22   A0A0L7R555   A0A1I8M9G1   A0A0C9Q832   B4LE43   A0A2H8TIE0   A0A195AZH9   A0A1I8NYX2   A0A158NH31   A0A195D1G1   A0A195F5X6   B4IYI8   A0A0L0BPV9   A0A2S2R6Y2   B4KWL8   A0A088AK37   W8BCZ6   A0A2R7VSW2   A0A0A1X0K9   A0A0K8UUN5   A0A034VMD1   A0A0K2UX35   K7IRE2   A0A232F2W2   A0A3R7MSF5   E2BSD9   A0A3L8DN93   A0A336L365  

Pubmed

19121390    16707581    28756777    26354079    24845553    18054377    + More
18025266    18362917    18316733    20068045    19820115    21843505    23604020    20966253    12364791    14747013    17210077    25244985    20566863    26483478    24438588    28004739    17510324    30735632    23932938    20920257    23761445    17994087    18057021    21719571    29403074    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12218185    12438685    22936249    24508170    17550304    15632085    20798317    25315136    21347285    26108605    24495485    25830018    25348373    20075255    28648823    30249741   

EMBL

BABH01003378    AB253536    BAE93472.1    ODYU01010412    SOQ55497.1    KZ150358    + More
PZC71216.1    KT031037    ALM88335.1    KQ459596    KPI95295.1    KQ459717    KPJ20327.1    CVRI01000047    CRK97175.1    CRK97179.1    NEVH01002577    PNF41890.1    AJVK01010888    KK852460    KDR23532.1    AJWK01025419    AJWK01025420    BK006097    KQ971317    DAA64478.1    EEZ99319.1    APCN01002079    AXCN02000187    AAAB01008987    EAA01756.2    DS235283    EEB14381.1    AXCM01003217    AY299455    AAQ73620.1    JXUM01115592    KQ565895    KXJ70560.1    ATLV01015774    KE525036    KFB40667.1    GEZM01010762    GEZM01010761    GEZM01010760    GEZM01010759    JAV93845.1    CH901475    EAT32276.2    CH477270    EAT45357.2    MH810178    QBC65443.1    AB817323    BAO01090.1    DS231975    EDS30001.1    ADMH02000641    ETN65478.1    GEBQ01009926    JAT30051.1    GECZ01004348    JAS65421.1    GECU01035023    JAS72683.1    KQ434998    KZC13291.1    CH480817    EDW50254.1    CH902618    EDV39857.1    KPU78249.1    GL888327    EGI62765.1    PYGN01000784    PSN40838.1    AE014296    AGB94042.1    AHN57950.1    AF351129    BK000442    AAF47700.1    AAL83921.1    DAA00378.1    CM000363    CM002912    EDX08999.1    KMY97215.1    KK107566    EZA48896.1    JXJN01009322    CM000159    EDW93874.1    CH379070    EAL30220.1    CH954178    EDV50355.1    ABLF02039963    ABLF02039969    ABLF02039979    CCAG010013759    KQ981091    KYN09544.1    ACPB03008224    OUUW01000002    SPP77112.1    CP012525    ALC43006.1    EU785049    ACI90286.1    KQ760357    OAD60755.1    KQ982294    KYQ58366.1    GL437990    EFN69729.1    CH963847    EDW73578.1    KQ414654    KOC65978.1    GBYB01010343    JAG80110.1    CH940647    EDW70086.1    GFXV01001966    MBW13771.1    KQ976698    KYM77447.1    ADTU01015499    KQ976973    KYN06686.1    KQ981768    KYN35873.1    CH916366    EDV97661.1    JRES01001546    KNC22120.1    GGMS01016257    MBY85460.1    CH933809    EDW19647.1    KRG06723.1    GAMC01015549    JAB91006.1    KK854028    PTY09770.1    GBXI01009861    JAD04431.1    GDHF01021895    GDHF01006817    JAI30419.1    JAI45497.1    GAKP01014456    JAC44496.1    HACA01025076    CDW42437.1    NNAY01001120    OXU25071.1    QCYY01000505    ROT84744.1    GL450203    EFN81391.1    QOIP01000006    RLU21914.1    UFQS01001431    UFQT01001431    SSX10853.1    SSX30533.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000183832    UP000235965    UP000092462    + More
UP000027135    UP000092461    UP000007266    UP000075903    UP000075885    UP000075902    UP000075882    UP000075840    UP000076407    UP000075886    UP000007062    UP000076408    UP000075884    UP000075920    UP000075900    UP000009046    UP000075883    UP000069940    UP000249989    UP000030765    UP000008820    UP000075880    UP000069272    UP000002320    UP000000673    UP000076502    UP000001292    UP000007801    UP000007755    UP000245037    UP000000803    UP000000304    UP000053097    UP000092460    UP000092443    UP000002282    UP000001819    UP000008711    UP000007819    UP000092444    UP000078492    UP000015103    UP000268350    UP000092553    UP000075809    UP000000311    UP000192221    UP000007798    UP000053825    UP000095301    UP000008792    UP000078540    UP000095300    UP000005205    UP000078542    UP000078541    UP000001070    UP000037069    UP000009192    UP000005203    UP000002358    UP000215335    UP000283509    UP000008237    UP000279307   

PRIDE

H9JEN3    Q1MW82    Q9VZW5   

Pfam

PF10324   7TM_GPCR_Srw        + More
PF00001   7tm_1

Interpro

IPR019427   7TM_GPCR_serpentine_rcpt_Srw        + More
IPR017452   GPCR_Rhodpsn_7TM       
IPR000276   GPCR_Rhodpsn       

ProteinModelPortal

H9JEN3   Q1MW82   A0A2H1WR64   A0A2W1BE79   A0A0S1YDJ3   A0A194PVY8   + More
A0A0N0PF39   A0A1J1IA62   A0A2J7RM31   A0A1B0D359   A0A067RIB2   A0A1B0CRX1   D6WCQ8   A0A182V7A9   A0A182PKD3   A0A182U6E5   A0A182KM77   A0A182I0I1   A0A182XBP5   A0A182Q005   Q7PYB7   A0A182YJX1   A0A182N4X7   A0A182VQV3   A0A182RBX4   E0VLX5   A0A182MKG8   Q1EHB5   A0A182H745   A0A084VRS3   A0A1Y1NB30   Q1DGJ7   Q17FI7   A0A182JK10   A0A1S4F4M7   U3U7P6   A0A182F6Y2   B0WKQ9   W5JQB2   A0A1B6M289   A0A1B6GSL8   A0A1B6HDC3   A0A154PN34   B4HTI3   B3M7F9   F4WSQ5   A0A2P8Y9A7   M9PBK3   Q9VZW5   B4QP04   A0A026VZK6   A0A1B0B700   A0A1A9YIC2   B4PCX0   Q29E43   B3NF13   X1WJ26   A0A1B0GFN0   A0A151ISG2   T1HBY9   A0A3B0JAT3   A0A0M5J5H2   F8J1K6   A0A310STP5   A0A151XDB0   E2AA00   A0A1W4VPK2   B4MN22   A0A0L7R555   A0A1I8M9G1   A0A0C9Q832   B4LE43   A0A2H8TIE0   A0A195AZH9   A0A1I8NYX2   A0A158NH31   A0A195D1G1   A0A195F5X6   B4IYI8   A0A0L0BPV9   A0A2S2R6Y2   B4KWL8   A0A088AK37   W8BCZ6   A0A2R7VSW2   A0A0A1X0K9   A0A0K8UUN5   A0A034VMD1   A0A0K2UX35   K7IRE2   A0A232F2W2   A0A3R7MSF5   E2BSD9   A0A3L8DN93   A0A336L365  

PDB

4ZJC     E-value=8.37173e-07,     Score=127

KEGG

692556    no KO assigned | (RefSeq) FaR, BRFaR; FMRFamide receptor

GO

GO:0008528   GO:0016021   GO:0004930   GO:0007218   GO:0008344   GO:0008188   GO:0005887   GO:0007204   GO:0008345   GO:0002209   GO:0001653   GO:0007186   GO:0022891   GO:0004812   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

Subcellular location

Cell membrane  

Length:

412

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

150.11517

Exp number, first 60 AAs:

23.35322

Total prob of N-in:

0.01788

POSSIBLE N-term signal

sequence

outside

1  -  27

TMhelix

28  -  50

inside

51  -  62

TMhelix

63  -  85

outside

86  -  104

TMhelix

105  -  127

inside

128  -  147

TMhelix

148  -  165

outside

166  -  202

TMhelix

203  -  225

inside

226  -  245

TMhelix

246  -  268

outside

269  -  291

TMhelix

292  -  309

inside

310  -  412

 

 

Pi

67.246843

Theta

53.624961

Tajima's D

-0.634137

CLR

17.576446

CSRT

0.212739363031848

Interpretation

Uncertain