Gene

KWMTBOMO08563

Pre Gene Modal

BGIBMGA009309

Annotation

PREDICTED:_kinesin-like_protein_Klp68D_[Bombyx_mori]

Location

Bomo_Chr14(-):13228386-13268024      View in EpiBrowser

Full name

Kinesin-like protein       + More
Eukaryotic translation initiation factor 3 subunit K      
Kinesin-like protein Klp68D      

Alternative Name

eIF-3 p25

Location in the cell

Nuclear   Reliability : 2.177

CDS

ATGGAGAAGTCTGCCCGGCCAAGAACTGCACTTAACGAATGTGTGAAAGTGGTAGTACGATGCAGACCTCTCTCTGAACGTGAAAAAAAGGAAGGCTACGACGAGGTGGTGAAAGTATGGCCGGAGCGCGGGGCAGTCCAGGTGTACAACCCGAAGGGCCAGGACAAGCTGTTCACGTACGACGCCGCCTACGACAGCTCGGCCGACACGCAGACCATATACGACGAGATGGTACGTCCCCTGGTCGCGTCGGTACTGGACGGATTCAATGGCTGCGTGTTCGCTTACGGACAGACGGGCACCGGCAAGACGCACACGATGGAGGGTACCCCCGACCACGAGGGAGTCATCCCGCGAGCCTTCCGACACATATGGGCGCACATCGAGAATAACGCCTCTCCTGATGTCACGCATCTGGTATCCTGCTCCTACGTCGAACTGTACTTAGAGGACGTACGGGATCTGCTATCGAAGGACTGCAAGAAACTGACCATTAGAGGACAGGAGCTGAACGGTTTCTACATCCCGGAGATGACGTCAATTGTGTGCAAGTCCGCGGCGGAGATGGTGCGCGTGATGCGAGCCGGCAACAAGCACCGCGCCGCCGGCCGCACCGACATGAACGAGCACTCGTCCAGAAGCCACGCCGTGTTCCTCGTCACCGTCGAGACGGCCCACAGGAAGACTAATCGAATACGCGTGGGCAAGTTGAACCTCGTGGACCTGGCGGGAAGCGAGCGGCAGTCCAAAACGGGCGCCTCCGCGGACAGACTGCGCGAGGCTTCTCGCATCAACCAGGCCCTCTCCTCCCTGGGAAACGTCATCTCCGCGCTCGCAGAGAACAGCCCCCACGTGCCGTACAGGGACTCGAAGCTGACTCGGATTCTGCAGGACTCGCTGGGCGGCAACAGCAAGACCATAATGATCGCGAACATCGGGCCCGCCTCCTACAACTACGACGAGACCGTCACCACGCTGCGGTACGCGCACCGCGCCAAAGCGATAAAGAACAAGCCGGTCCGCAACGAGGACCCGAAGGACGCCAAGCTGCGCGAGTACCAGGCCGAGATCGAGCGACTCCGCGCGCTCATCGAGCAGAGGAAGCTCATCGAGAAGCGGCCCAGGAAGCCGCGCCCCGCCAGGCCGCACCCCGACAACGCAGCGGAAGACGACACGCTCAGTATAGAGAACGAGAACATTCTAGCGGAATCTACGATAGAACAAGAAAAAGTAAAGACTGAAGAATTGGAGCAACAGATTCGATCGCTGGAGGACCGGCTCGTGCAGGGCGGTGCGGGGAAGGACCTCATCAACAACCTCAACGAGAGCCAAATTATACTAGAGCAGAGGAACCTCGAGATCGCGGAGAGGAAGAACAGAGAGGTGGAGATGCAGCAGAAGATAGAGCTGGAGGAGGAGACCGCCGCCATCGTCACCAACACGTTCGCGACCCTGCAGCAAGAGGTCGACCACAAGACGCAGAGGTTGAAGAAGTGCCTGTCGAAGTACGCGGGGCTGCGCGAGGAGATGGTGGAGCAGCGCGAGGCGCACGACGCGGAGCGGCGCGAGCGGGAGGCGCTGCAGGCCGCGCTGGTGGGGGCGCTGCGCCGCCGCCTGCTGCTCGCCGACAGCTTCGTGCCGCTGGCCGGCCGCCCCGCCGCGCTGCGGGCGCGCTACGACGACGACCGCGACGTGTGGGACCTCGCCCCCCCCGCGCCCCTGGAGCCGCTGCTCGAGCGGCCCCGCGCCCGCCCCCGCGCCCCCCCGCGCGCGCTGCTGGCGCTCGCCCCCCTGCCGCTGCCGCCCACCACGCGCCTCTACGTGCCGCCGCAGGTTCGTACATACGGCCCACTAATCGGCTGTGTAGCGGCTGCCCCATCTTACTGCGTTTATAGACGTATTGTAGACGTTTGGAACACTGCGATATTCGCAGCGGCGGACGACTACAATAAATCAACATCTAATCTGTATAATCTAATGTTTTGTGTGATCTAG

Protein

MEKSARPRTALNECVKVVVRCRPLSEREKKEGYDEVVKVWPERGAVQVYNPKGQDKLFTYDAAYDSSADTQTIYDEMVRPLVASVLDGFNGCVFAYGQTGTGKTHTMEGTPDHEGVIPRAFRHIWAHIENNASPDVTHLVSCSYVELYLEDVRDLLSKDCKKLTIRGQELNGFYIPEMTSIVCKSAAEMVRVMRAGNKHRAAGRTDMNEHSSRSHAVFLVTVETAHRKTNRIRVGKLNLVDLAGSERQSKTGASADRLREASRINQALSSLGNVISALAENSPHVPYRDSKLTRILQDSLGGNSKTIMIANIGPASYNYDETVTTLRYAHRAKAIKNKPVRNEDPKDAKLREYQAEIERLRALIEQRKLIEKRPRKPRPARPHPDNAAEDDTLSIENENILAESTIEQEKVKTEELEQQIRSLEDRLVQGGAGKDLINNLNESQIILEQRNLEIAERKNREVEMQQKIELEEETAAIVTNTFATLQQEVDHKTQRLKKCLSKYAGLREEMVEQREAHDAERREREALQAALVGALRRRLLLADSFVPLAGRPAALRARYDDDRDVWDLAPPAPLEPLLERPRARPRAPPRALLALAPLPLPPTTRLYVPPQVRTYGPLIGCVAAAPSYCVYRRIVDVWNTAIFAAADDYNKSTSNLYNLMFCVI

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Plus-end directed microtubule motor that may be used for anterograde axonal transport and could conceivably move cargos in fly neurons different than those moved by kinesin heavy chain or other plus-end directed motors.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Belongs to the eIF-3 subunit K family.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.

Keywords

ATP-binding   Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Microtubule   Motor protein   Nucleotide-binding   Reference proteome  

Feature

chain  Kinesin-like protein Klp68D

Uniprot

A0A2A4K1Y7   A0A212FFU4   A0A437B5C1   A0A194RBP4   A0A1L8E5K3   A0A1I8PAF6   + More
W8BCT9   A0A1B0A4A5   A0A1A9XEE5   A0A1B0AYT2   A0A084W6U8   A0A0L0BSJ6   T1PCC8   A0A1I8M1R0   A0A1A9UYL7   A0A0K8VIQ0   U5EW20   A0A034W161   A0A1B0G9H9   A0A0K8TNV2   A0A336MQK5   B4LCS9   A0A336MLZ9   A0A0A1XBT5   B3M4C8   A0A182ISY3   A0A3B0J8W7   A0A1A9WXS4   A0A1W4VTB1   B3NH09   B4IZA3   B4KUU3   B4N736   B4PFP6   A0A0R3P8S8   Q29DY1   B4QQN1   A0A1J1I6H1   A0A182FBL4   A0A0J9RUW9   B4HEZ2   A0A2M4AJK7   A0A182GF84   A0A1Y1L0H8   M9PF68   P46867   A0A1Y1L0Q1   A0A2M4BDZ7   A0A182JS84   A0A1B0CM91   A0A1S4H3V7   A0A182HX57   A0A182VJ40   A0A182XFN7   W5JWD9   Q7QDS6   A0A182U6K5   Q17N32   A0A182PUF0   A0A1Q3F530   A0A1Q3F501   A0A0M4EZ12   A0A182QVM8   A0A182R8W9   A0A182N2X8   A0A182W8C2   A0A182MVM0   B0X211   A0A0T6B9X5   N6UES0   U4UIR1   A0A026WDE8   D6X561   E2C7W6   A0A182YE74   E9J3X6   E2AFH7   A0A195ERI8   F4WKD7   A0A195DHT1   A0A158P1Q8   A0A151XAV3   A0A195BS52   A0A195CMA6   T1IFB2   A0A2J7PUC0   A0A0A9Y1C5   A0A146KP42   A0A154PKU1   A0A0L7QM35   A0A088AEK9   A0A0M8ZYA7   A0A232FHB0   A0A2A3E765   V9IK77   A0A023EZY2   A0A224XJC4   K7ISZ1   A0A0J7L3H3   A0A293LCD5  

Pubmed

22118469    26354079    24495485    24438588    26108605    25315136    + More
25348373    26369729    17994087    25830018    17550304    15632085    22936249    26483478    28004739    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    7525600    12537569    1924306    12364791    20920257    23761445    17510324    23537049    24508170    30249741    18362917    19820115    20798317    25244985    21282665    21719571    21347285    25401762    26823975    28648823    25474469    20075255   

EMBL

NWSH01000219    PCG78281.1    AGBW02008766    OWR52593.1    RSAL01000154    RVE45672.1    + More
KQ460436    KPJ14695.1    GFDF01000138    JAV13946.1    GAMC01007465    JAB99090.1    JXJN01005947    ATLV01020956    KE525310    KFB45942.1    JRES01001431    KNC22948.1    KA645593    AFP60222.1    GDHF01013548    JAI38766.1    GANO01001621    JAB58250.1    GAKP01011087    GAKP01011081    GAKP01011077    JAC47865.1    CCAG010001505    GDAI01002018    JAI15585.1    UFQS01001435    UFQT01001435    SSX10879.1    SSX30557.1    CH940647    EDW70971.1    UFQT01001190    SSX29397.1    GBXI01016938    GBXI01005887    JAC97353.1    JAD08405.1    CH902618    EDV39398.1    OUUW01000002    SPP76753.1    CH954178    EDV51466.1    CH916366    EDV96658.1    CH933809    EDW19349.1    CH964168    EDW80175.1    CM000159    EDW94195.1    CH379070    KRT08789.1    EAL30282.1    CM000363    EDX10133.1    CVRI01000043    CRK95795.1    CM002912    KMY99074.1    CH480815    EDW41161.1    GGFK01007645    MBW40966.1    JXUM01059550    KQ562059    KXJ76792.1    GEZM01068124    JAV67163.1    AE014296    AGB94420.1    U15974    AY051583    M74431    GEZM01068123    JAV67164.1    GGFJ01002096    MBW51237.1    AJWK01018373    AJWK01018374    AJWK01018375    AAAB01008849    APCN01005143    ADMH02000071    ETN67908.1    EAA07222.4    CH477202    EAT48111.1    GFDL01012373    JAV22672.1    GFDL01012409    JAV22636.1    CP012525    ALC43850.1    AXCN02002298    AXCM01001621    DS232276    EDS38941.1    LJIG01009134    KRT83687.1    APGK01029738    APGK01029739    APGK01029740    APGK01029741    APGK01029742    APGK01029743    APGK01029744    APGK01029745    APGK01029746    APGK01029747    KB740741    ENN79101.1    KB632375    ERL93914.1    KK107274    QOIP01000008    EZA53676.1    RLU19209.1    KQ971382    EEZ97207.2    GL453494    EFN75964.1    GL768069    EFZ12474.1    GL439108    EFN67870.1    KQ982021    KYN30517.1    GL888199    EGI65361.1    KQ980824    KYN12455.1    ADTU01006753    KQ982335    KYQ57477.1    KQ976419    KYM89339.1    KQ977595    KYN01602.1    ACPB03000974    NEVH01021202    PNF19932.1    GBHO01018686    JAG24918.1    GDHC01020365    JAP98263.1    KQ434947    KZC12367.1    KQ414906    KOC59581.1    KQ435817    KOX72556.1    NNAY01000247    OXU29727.1    KZ288358    PBC27066.1    JR051236    AEY61460.1    GBBI01003909    JAC14803.1    GFTR01007866    JAW08560.1    AAZX01005553    LBMM01001078    KMQ96969.1    GFWV01001632    MAA26362.1   

Proteomes

UP000218220    UP000007151    UP000283053    UP000053240    UP000095300    UP000092445    + More
UP000092443    UP000092460    UP000030765    UP000037069    UP000095301    UP000078200    UP000092444    UP000008792    UP000007801    UP000075880    UP000268350    UP000091820    UP000192221    UP000008711    UP000001070    UP000009192    UP000007798    UP000002282    UP000001819    UP000000304    UP000183832    UP000069272    UP000001292    UP000069940    UP000249989    UP000000803    UP000075881    UP000092461    UP000075840    UP000075903    UP000076407    UP000000673    UP000007062    UP000075902    UP000008820    UP000075885    UP000092553    UP000075886    UP000075900    UP000075884    UP000075920    UP000075883    UP000002320    UP000019118    UP000030742    UP000053097    UP000279307    UP000007266    UP000008237    UP000076408    UP000000311    UP000078541    UP000007755    UP000078492    UP000005205    UP000075809    UP000078540    UP000078542    UP000015103    UP000235965    UP000076502    UP000053825    UP000005203    UP000053105    UP000215335    UP000242457    UP000002358    UP000036403   

PRIDE

Q29DY1    P46867   

Pfam

PF00225   Kinesin        + More
PF10075   CSN8_PSD8_EIF3K

Interpro

IPR019821   Kinesin_motor_CS        + More
IPR027417   P-loop_NTPase       
IPR036961   Kinesin_motor_dom_sf       
IPR001752   Kinesin_motor_dom       
IPR027640   Kinesin-like_fam       
IPR033464   CSN8_PSD8_EIF3K       
IPR009374   eIF3k       
IPR016020   Transl_init_fac_sub12_N_euk       
IPR000717   PCI_dom       
IPR016024   ARM-type_fold       
IPR036390   WH_DNA-bd_sf       
IPR036388   WH-like_DNA-bd_sf       

SUPFAM

SSF52540   SSF52540        + More
SSF46785   SSF46785       
SSF48371   SSF48371       

Gene 3D

3.40.850.10     1.10.10.10     1.25.40.250    

ProteinModelPortal

A0A2A4K1Y7   A0A212FFU4   A0A437B5C1   A0A194RBP4   A0A1L8E5K3   A0A1I8PAF6   + More
W8BCT9   A0A1B0A4A5   A0A1A9XEE5   A0A1B0AYT2   A0A084W6U8   A0A0L0BSJ6   T1PCC8   A0A1I8M1R0   A0A1A9UYL7   A0A0K8VIQ0   U5EW20   A0A034W161   A0A1B0G9H9   A0A0K8TNV2   A0A336MQK5   B4LCS9   A0A336MLZ9   A0A0A1XBT5   B3M4C8   A0A182ISY3   A0A3B0J8W7   A0A1A9WXS4   A0A1W4VTB1   B3NH09   B4IZA3   B4KUU3   B4N736   B4PFP6   A0A0R3P8S8   Q29DY1   B4QQN1   A0A1J1I6H1   A0A182FBL4   A0A0J9RUW9   B4HEZ2   A0A2M4AJK7   A0A182GF84   A0A1Y1L0H8   M9PF68   P46867   A0A1Y1L0Q1   A0A2M4BDZ7   A0A182JS84   A0A1B0CM91   A0A1S4H3V7   A0A182HX57   A0A182VJ40   A0A182XFN7   W5JWD9   Q7QDS6   A0A182U6K5   Q17N32   A0A182PUF0   A0A1Q3F530   A0A1Q3F501   A0A0M4EZ12   A0A182QVM8   A0A182R8W9   A0A182N2X8   A0A182W8C2   A0A182MVM0   B0X211   A0A0T6B9X5   N6UES0   U4UIR1   A0A026WDE8   D6X561   E2C7W6   A0A182YE74   E9J3X6   E2AFH7   A0A195ERI8   F4WKD7   A0A195DHT1   A0A158P1Q8   A0A151XAV3   A0A195BS52   A0A195CMA6   T1IFB2   A0A2J7PUC0   A0A0A9Y1C5   A0A146KP42   A0A154PKU1   A0A0L7QM35   A0A088AEK9   A0A0M8ZYA7   A0A232FHB0   A0A2A3E765   V9IK77   A0A023EZY2   A0A224XJC4   K7ISZ1   A0A0J7L3H3   A0A293LCD5  

PDB

3B6U     E-value=2.31716e-108,     Score=1005

KEGG

101744927    K20196 kinesin family member 3B | (RefSeq) kinesin-like protein Klp68D

GO

GO:0007018   GO:0003777   GO:0005524   GO:0008017   GO:0005874   GO:0006446   GO:0016282   GO:0043022   GO:0003743   GO:0005852   GO:0001732   GO:0033290   GO:0007608   GO:0005875   GO:1904115   GO:0030951   GO:0008089   GO:0003774   GO:0005871   GO:0016887   GO:0022891   GO:0004812   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

PANTHER

PTHR24115  

Subcellular location

Cytoplasm  
  

Length:

664

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.5631

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01122

outside

1  -  664

 

 

Pi

178.237887

Theta

16.682475

Tajima's D

-0.725316

CLR

1358.987482

CSRT

0.191840407979601

Interpretation

Uncertain