Gene

KWMTBOMO08543  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009319

Annotation

ribosomal_protein_S3_[Bombyx_mori]

Location

Bomo_Chr14(-):12514943-12518432      View in EpiBrowser

Full name

40S ribosomal protein S3       + More
40S ribosomal protein S3-A      

Alternative Name

S1A

Location in the cell

Cytoplasmic   Reliability : 1.97 Mitochondrial   Reliability : 1.666

CDS

ATGGCCGTGAACAATATTTCAAAGAAGCGAAAATTTGTTGGAGATGGAGTTTTCAAGGCGGAACTCAATGAGTTCCTCACTAGGGAGCTGGCCGAGGACGGCTACTCCGGCGTGGAAGTCCGGGTCACTCCCATCCGCTCGGAGATCATTATTATGGCCACCAGGACACAAAGTGTGCTCGGAGAGAAAGGACGCAGAATCCGTGAGCTGACTTCCGTAGTACAGAAGCGATTCAACATTCCAGAGCAATCTGTAGAATTGTATGCTGAAAAGGTGGCTACTCGTGGTCTTTGCGCTATCGCCCAGGCCGAATCTCTAAGATACAAGCTTATCGGAGGTCTCGCTGTACGTCGTGCTTGCTATGGTGTTCTCCGTTTCATCATGGAATCTGGCGCCCGTGGTTGTGAAGTTGTTGTATCTGGCAAGCTGCGTGGTCAACGTGCCAAATCAATGAAGTTTGTAGATGGACTCATGATCCACTCTGGAGACCCTTGCAATGACTACGTCAACACTGCTACCAGACATGTGCTTCTCAGGCAAGGAGTACTAGGAATCAAGGTCAAAATCATGTTGCCGTGGGACCAGCAAGGCAAGAACGGCCCGAAGAAGCCACAACCAGACCACATCCTGGTGACAGAGCCCAAGGACGAGCCCGTGCCCCTCGAGCCGACCAGCGAAGTGCGCTCCCTCGCGCCCGCGCCTCTGCCGCAGCCGGTCGCCGCTGTCGCTTAG

Protein

MAVNNISKKRKFVGDGVFKAELNEFLTRELAEDGYSGVEVRVTPIRSEIIIMATRTQSVLGEKGRRIRELTSVVQKRFNIPEQSVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRACYGVLRFIMESGARGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPCNDYVNTATRHVLLRQGVLGIKVKIMLPWDQQGKNGPKKPQPDHILVTEPKDEPVPLEPTSEVRSLAPAPLPQPVAAVA

Description

Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Also involved in other processes including regulation of transcription, translation of its cognate mRNA, spindle formation and chromosome movement during mitosis, and apoptosis.

Catalytic Activity

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

Similarity

Belongs to the universal ribosomal protein uS3 family.

Keywords

Ribonucleoprotein   Ribosomal protein   RNA-binding   Apoptosis   Cell cycle   Cell division   Cytoplasm   Cytoskeleton   DNA damage   DNA repair   DNA-binding   Lyase   Membrane   Mitochondrion   Mitochondrion inner membrane   Mitosis   Nucleus   Transcription   Transcription regulation   Translation regulation  

Feature

chain  40S ribosomal protein S3

Uniprot

Q5UAP2   A0A2H1WTQ8   E7DYZ6   A0A3G1T1G0   A0A089RLZ6   A0A0N1IP25   + More
I4DIK4   I4DLY2   P48153   A0A0A1E4H3   Q95V36   A0A212FND8   G0ZEB3   Q000A7   A0A0L7LNM2   A0A3S2LEV6   Q6EV28   Q4GXR1   A0A0N9MP84   A0A1W4XWB0   A0A146KR45   A0A1B1NJ06   A0A1Y1LA29   A0A1D1XCH0   A0A067R1U8   A0A2P8XV80   Q6EV05   A0A2J7R3C1   A0A0U2TI96   K7J8W6   R4V2V4   A2IA98   A0A1B0GIF5   A0A0C9QZ78   A0A1B6M639   A0A0X8NRC9   A0A0U2V6K3   A0A154NXU5   Q56FH9   A0A026W1G3   A0A077CUU1   D1M7X5   A0A1L8HJY0   P02350   Q7ZYT3   V5H4W7   A0A3Q2DY75   A0A1B1MRN5   A0A0U2T8D0   A0A0U2UT23   G3PJC8   U5EUR5   M1K4Y5   B5DGY5   W5MH79   C0H7T0   B5XAC5   A0A3B3XT32   A0A3B5Q286   A0A3B5LZC5   A0A087Y773   A0A3B3VA71   A0A3P9PWI0   A0A1L8DSD4   A0A0S7MHH5   A0A060VTT3   A0A2V2PN55   A0A3B3QSN6   A0A0K2UH90   A0A1B6GTJ0   A0A0U2UH62   A0A1S3LP02   A0A3P8ZA90   E2BHI4   A0A1A8FTZ9   A0A1A7YWJ2   A0A0E9WR13   A0A0B8RP95   A0A060WYE0   A0A1A8GP69   K9J1W0   F6RG35   Q6QZI0   A0A088AV85   A0A1W7R9N7   A0A1A8P4X7   A0A1A8Q4S8   A0A1A8I5S5   A0A1A8E8E0   A0A1A8UXU3   A0A348G678   A0A1S3F049   A0A3L7HXG6   I3N0Y3   A0A1U7Q9Q4   A0A250YDI8   A0A286XTB7   A0A091D1I9   Q5YLW3   L5JLX8  

EC Number

4.2.99.18

Pubmed

19121390    27163122    26354079    22651552    8630533    14668217    + More
22118469    16885282    26227816    26823975    28004739    24845553    29403074    26621068    20075255    17437641    24508170    30249741    27762356    2030971    7049839    19878547    20433749    23542700    24755649    29240929    25069045    20798317    25613341    25476704    17495919    15792627    29704459    28087693    21993624    10349636    11042159    11076861    11217851    12466851    12040188    16141073    16356660    17242355    19144319    21183079    23806337    23258410   

EMBL

BABH01027225    AY769316    AAV34858.1    ODYU01010995    SOQ56459.1    HQ424699    + More
ADT80643.1    MG992382    AXY94820.1    KM064630    KT962961    AIR07416.1    AND95944.1    KQ460817    KPJ12125.1    AK401122    KQ459337    BAM17744.1    KPJ01370.1    AK402300    BAM18922.1    U12708    KJ405954    AIY22794.1    AF429976    AAL26578.1    AGBW02006209    OWR55233.1    JF264991    AEL28822.1    DQ988989    ABJ55992.1    JTDY01000523    KOB76806.1    RSAL01000024    RVE52215.1    AJ783759    CAH04122.1    AM048962    CAJ17197.1    KR080494    ALG76022.1    GDHC01020902    JAP97726.1    KT274801    ANS83636.1    GEZM01063261    JAV69160.1    GDJX01027940    JAT39996.1    KK852773    KDR16813.1    PYGN01001295    PSN35918.1    AJ783866    CAH04314.1    NEVH01007822    PNF35323.1    KT755242    ALS05076.1    AAZX01000813    AAZX01013133    KC632284    AGM32098.1    EF179412    ABM55418.1    AJWK01014059    GBYB01006002    JAG75769.1    GEBQ01008623    JAT31354.1    KC507300    AHB12423.1    KT754746    KT754747    ALS04581.1    KQ434778    KZC04433.1    AY961521    AAX62423.1    KK107488    QOIP01000012    EZA49902.1    RLU15845.1    KJ868729    AIL23530.1    GU120399    ACY71249.1    CM004468    OCT96376.1    X57322    BC042230    V01441    BC041299    BC169756    BC169758    CM004469    AAH41299.1    AAI69756.1    OCT93347.1    GALX01000613    JAB67853.1    KU521367    ANS71247.1    KT755094    ALS04928.1    KT754933    ALS04767.1    GANO01002203    JAB57668.1    KC109783    AGF29412.1    BT043894    BT047476    BT058725    ACH71009.1    ACI67277.1    ACN10438.1    AHAT01003067    BT058386    BT060087    ACN10099.1    ACN12447.1    BT047994    ACI67795.1    AYCK01004889    GFDF01004773    JAV09311.1    GBYX01024237    JAP01208.1    FR904302    CDQ58373.1    QGNU01000090    PWS23245.1    HACA01020212    CDW37573.1    GECZ01004106    JAS65663.1    KT755329    ALS05163.1    GL448301    EFN84837.1    HAEB01016348    SBQ62875.1    HADX01012745    SBP34977.1    GBXM01015780    JAH92797.1    GBSH01002387    JAG66639.1    FR904677    CDQ69610.1    HAEC01004117    SBQ72194.1    GABZ01002484    JAA51041.1    AY521669    AAT01919.1    GFAH01000533    JAV47856.1    HAEI01001427    SBR76129.1    HAEF01004352    HAEG01010947    SBR88458.1    HAED01005343    HAEE01014299    SBQ91373.1    HADZ01001902    HAEA01012889    SBQ41369.1    HADY01019651    HAEJ01012762    SBS53219.1    FX985620    BBF97951.1    RAZU01000137    RLQ70634.1    AGTP01028900    GFFW01003189    JAV41599.1    AAKN02051174    KN123669    KFO24040.1    AY043296    AK003181    AK010579    AK012234    AK051243    AK146796    AK148030    AK159508    AK160526    AK164077    AK165174    AK166750    AK167210    AK167266    AK168845    CH466531    AAK95377.1    BAB22624.1    BAC34570.1    BAE27438.1    BAE35844.1    BAE37615.1    BAE40668.1    EDL16392.1    KB031158    ELK00374.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000037510    UP000283053    + More
UP000192223    UP000027135    UP000245037    UP000235965    UP000002358    UP000092461    UP000076502    UP000053097    UP000279307    UP000186698    UP000265020    UP000007635    UP000087266    UP000018468    UP000261480    UP000002852    UP000261380    UP000028760    UP000261500    UP000242638    UP000193380    UP000245538    UP000261540    UP000265140    UP000008237    UP000002280    UP000005203    UP000081671    UP000273346    UP000005215    UP000189706    UP000005447    UP000028990    UP000010552   

PRIDE

Q5UAP2    P48153    P02350    A0A088AV85   

Pfam

PF00189   Ribosomal_S3_C        + More
PF07650   KH_2

Interpro

IPR005703   Ribosomal_S3_euk/arc        + More
IPR036419   Ribosomal_S3_C_sf       
IPR004044   KH_dom_type_2       
IPR001351   Ribosomal_S3_C       
IPR015946   KH_dom-like_a/b       
IPR018280   Ribosomal_S3_CS       
IPR009019   KH_sf_prok-type       

SUPFAM

SSF54821   SSF54821        + More
SSF54814   SSF54814       

Gene 3D

3.30.1140.32     3.30.300.20    

ProteinModelPortal

Q5UAP2   A0A2H1WTQ8   E7DYZ6   A0A3G1T1G0   A0A089RLZ6   A0A0N1IP25   + More
I4DIK4   I4DLY2   P48153   A0A0A1E4H3   Q95V36   A0A212FND8   G0ZEB3   Q000A7   A0A0L7LNM2   A0A3S2LEV6   Q6EV28   Q4GXR1   A0A0N9MP84   A0A1W4XWB0   A0A146KR45   A0A1B1NJ06   A0A1Y1LA29   A0A1D1XCH0   A0A067R1U8   A0A2P8XV80   Q6EV05   A0A2J7R3C1   A0A0U2TI96   K7J8W6   R4V2V4   A2IA98   A0A1B0GIF5   A0A0C9QZ78   A0A1B6M639   A0A0X8NRC9   A0A0U2V6K3   A0A154NXU5   Q56FH9   A0A026W1G3   A0A077CUU1   D1M7X5   A0A1L8HJY0   P02350   Q7ZYT3   V5H4W7   A0A3Q2DY75   A0A1B1MRN5   A0A0U2T8D0   A0A0U2UT23   G3PJC8   U5EUR5   M1K4Y5   B5DGY5   W5MH79   C0H7T0   B5XAC5   A0A3B3XT32   A0A3B5Q286   A0A3B5LZC5   A0A087Y773   A0A3B3VA71   A0A3P9PWI0   A0A1L8DSD4   A0A0S7MHH5   A0A060VTT3   A0A2V2PN55   A0A3B3QSN6   A0A0K2UH90   A0A1B6GTJ0   A0A0U2UH62   A0A1S3LP02   A0A3P8ZA90   E2BHI4   A0A1A8FTZ9   A0A1A7YWJ2   A0A0E9WR13   A0A0B8RP95   A0A060WYE0   A0A1A8GP69   K9J1W0   F6RG35   Q6QZI0   A0A088AV85   A0A1W7R9N7   A0A1A8P4X7   A0A1A8Q4S8   A0A1A8I5S5   A0A1A8E8E0   A0A1A8UXU3   A0A348G678   A0A1S3F049   A0A3L7HXG6   I3N0Y3   A0A1U7Q9Q4   A0A250YDI8   A0A286XTB7   A0A091D1I9   Q5YLW3   L5JLX8  

PDB

6MTE     E-value=5.85526e-105,     Score=970

KEGG

692712    K02985 small subunit ribosomal protein S3e | (RefSeq) RpS3; ribosomal protein S3

PATHWAY

03010    Ribosome - Bombyx mori (domestic silkworm)

GO

GO:0015935   GO:0003723   GO:0006412   GO:0003735   GO:0005840   GO:0004364   GO:0051301   GO:0007049   GO:0006281   GO:0006915   GO:0006417   GO:0005743   GO:0005819   GO:0005730   GO:0003677   GO:0140078   GO:0030218   GO:0043009   GO:0045739   GO:0022627   GO:0003684   GO:0008534   GO:0003906   GO:2001235   GO:0005634   GO:0032357   GO:0051225   GO:0050862   GO:0005783   GO:0070301   GO:0044877   GO:0032587   GO:0005844   GO:1905053   GO:0032358   GO:0044390   GO:0000977   GO:0014069   GO:0061481   GO:0071356   GO:0072686   GO:0042769   GO:0008017   GO:0051092   GO:0032079   GO:0071159   GO:0070181   GO:0031397   GO:1902231   GO:0097100   GO:0031116   GO:0008134   GO:0003729   GO:0051879   GO:0010628   GO:0032743   GO:0051018   GO:0042104   GO:0017148   GO:1901224   GO:0007059   GO:0043507   GO:2001272   GO:0019901   GO:0030544   GO:0045738   GO:0005759   GO:1902546   GO:0004520   GO:0004812   GO:0006418   GO:0003676   GO:0016876   GO:0043039  

Subcellular location

Cytoplasm  
Nucleus  
Nucleolus  
Mitochondrion inner membrane  
Cytoskeleton  
Spindle  

Length:

243

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01711

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.27291

outside

1  -  243

 

 

Pi

427.381946

Theta

224.626624

Tajima's D

2.867981

CLR

0.136118

CSRT

0.970001499925004

Interpretation

Uncertain