SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO08537  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA009323
Annotation
PREDICTED:_putative_oxidoreductase_GLYR1_homolog_[Bombyx_mori]
Full name
Putative oxidoreductase GLYR1 homolog      
Alternative Name
Glyoxylate reductase 1 homolog
Nuclear protein NP60 homolog
Location in the cell
Nuclear   Reliability : 2.409
 

Sequence

CDS
ATGTCTGAAGGATATAAACTTGGGGATTTAGTTTGGGCGAAAATGAAGGGTTTCAGTCCTTGGCCTGGCCGGGTAGCGGTTCCCACTCCTGAACTTAGAACGCCGAAGAAGGCCACCAACGTACAATGCATTTACTTCTTTGGTACAAATAACTATGCTTGGATCGAAGACATCAACATCAAGCCGTACCAAGAGTTTAAGGAGCAGTTGATCAAATCCTGCAAGACGGCTGCGTTTAAAGAAGCCGTGAATCAAATCGAAGACTTCATTGAACATCCTGAGAAATTCGGAGATCTAGACGACCACACCCGTAACGTGGAGGAGGAATTCGATAAACTGAAGGAGAACGTCGAAGGAGACGACAGCAAAGAGGAGGCGACTGAAGCTGATGATGCACCCGCTCCAGAGTCTGCGAAGAAAAAGAGTTCCACGCCTAAGATACGTTTGGGCATTTCAAAGGTGAAGCCTATAAAGCGTGCCTCGTCGGCCGGCGTCAAGTCCACGCCGCGGAAGAAGGCAAAGAGTTCCCTCTCCAGGTCGTACACCGACTCCGATGTCGCCAACGAGAAGCCGTCGATGCTGAACCACTCGTTCTCCAAGAAGTCCAGCCTGTTGCAACGTCCCTCGAATATATTGAGACCTGAGACTCCCCCGCTGGACCTGGAGAACGTTTCTGAGACTCTTCTAGAGAAGAACATCAAGGCCAGCCAGATGAAGTTCGGCTTCCTCGGACTCGGCATCATGGGCTCGGGTATCGTGAAGAACCTCCTCAACTCGGGACACAAGGTCATCGTTTGGAACAGAACCGCGGCCAAGAAATATCTTCAGGCTCTTGTCTAA
Protein
MSEGYKLGDLVWAKMKGFSPWPGRVAVPTPELRTPKKATNVQCIYFFGTNNYAWIEDINIKPYQEFKEQLIKSCKTAAFKEAVNQIEDFIEHPEKFGDLDDHTRNVEEEFDKLKENVEGDDSKEEATEADDAPAPESAKKKSSTPKIRLGISKVKPIKRASSAGVKSTPRKKAKSSLSRSYTDSDVANEKPSMLNHSFSKKSSLLQRPSNILRPETPPLDLENVSETLLEKNIKASQMKFGFLGLGIMGSGIVKNLLNSGHKVIVWNRTAAKKYLQALV

Summary

Description
May have oxidoreductase activity.
Miscellaneous
The conserved NAD-binding sites suggest that this protein may have oxidoreductase activity.
Similarity
Belongs to the HIBADH-related family. NP60 subfamily.
Keywords
Complete proteome   NAD   Oxidoreductase   Reference proteome  
Feature
chain  Putative oxidoreductase GLYR1 homolog
EC Number
1.-.-.-
EMBL
ODYU01010995    SOQ56453.1    RSAL01000023    RVE52294.1    NWSH01002610    PCG67855.1    + More
AGBW02006209    OWR55239.1    PCG67856.1    KQ460817    KPJ12129.1    BABH01027215    KQ459337    KPJ01376.1    KQ982402    KYQ56858.1    ADTU01001056    ADTU01001057    ADTU01001058    ADTU01001059    ADTU01001060    ADTU01001061    GL437116    EFN71056.1    QOIP01000012    RLU15847.1    GL448228    EFN85056.1    NEVH01025635    PNF15379.1    KZ288192    PBC34298.1    JR038208    AEY58158.1    GEDC01013039    JAS24259.1    GEDC01022319    JAS14979.1    JXUM01031210    KQ560913    KXJ80367.1    GBYB01007492    GBYB01007494    JAG77259.1    JAG77261.1    GFDL01001212    JAV33833.1    ATLV01017581    KE525174    KFB42287.1    GEDC01019368    JAS17930.1    AXCM01002228    GDIQ01005978    JAN88759.1    GDIQ01117697    JAL34029.1    GDIP01228083    JAI95318.1    GDIP01070605    JAM33110.1    GDIP01228084    JAI95317.1    GECU01027695    JAS80011.1    GDIP01252332    LRGB01000872    JAI71069.1    KZS15433.1    GDIP01188990    JAJ34412.1    CH477401    GL888002    EGI69298.1    KQ414572    KOC71328.1    GECZ01007685    JAS62084.1    KQ435850    KOX70902.1    AJVK01010334    AJVK01010335    AXCN02000653    GGFK01003089    MBW36410.1    APCN01001690    AAAB01008980    GFDF01010486    JAV03598.1    ADMH02002138    ETN58343.1    GGFM01001964    MBW22715.1    GGFJ01003778    MBW52919.1    DS235243    EEB13855.1    GEZM01057056    JAV72474.1    GDIP01012526    JAM91189.1    KQ977720    KYN00496.1    GDAI01002062    JAI15541.1    GDIP01126305    JAL77409.1    KQ981855    KYN34855.1    GANO01000613    JAB59258.1    KQ980275    KYN17007.1    KK107488    EZA49910.1    UFQT01000023    SSX18021.1    ABLF02017887    ABLF02017889    ABLF02062618    GDIQ01227108    JAK24617.1    KQ434778    KZC04369.1    GDIP01144090    JAJ79312.1    GGLE01001541    MBY05667.1    GFJQ02004891    JAW02079.1    GDIQ01124086    JAL27640.1    GDRN01067921    JAI64295.1    GFPF01005553    MAA16699.1    GEDV01006170    JAP82387.1    KQ976418    KYM89496.1    GGMR01018042    MBY30661.1    ACPB03006490    PYGN01001092    PSN37674.1    GL732599    EFX72460.1    LJIJ01000222    ODN00228.1    SAUD01042376    RXG51071.1    CVRI01000055    CRL00964.1    KQ971338    EFA01759.1   
Pfam
PF00855   PWWP        + More
PF03446   NAD_binding_2
PF14833   NAD_binding_11
Interpro
IPR036291   NAD(P)-bd_dom_sf        + More
IPR000313   PWWP_dom       
IPR006115   6PGDH_NADP-bd       
IPR013328   6PGD_dom2       
IPR029154   NADP-bd       
IPR008927   6-PGluconate_DH-like_C_sf       
IPR035501   NP60_PWWP       
IPR002204   3-OH-isobutyrate_DH-rel_CS       
SUPFAM
SSF51735   SSF51735        + More
SSF48179   SSF48179       
Gene 3D
PDB
6IIT     E-value=1.45442e-09,     Score=149

Ontologies

Topology

Length:
279
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
2.46077
Exp number, first 60 AAs:
0.00579
Total prob of N-in:
0.01695
outside
1  -  279
 
 

Population Genetic Test Statistics

Pi
232.99073
Theta
205.1
Tajima's D
0.574353
CLR
0.392569
CSRT
0.529573521323934
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
26822097 FGDIDDHTR 95.24 7e-08
26280517 SYSIKPGTMIEWGNNWAR 95.24 7e-08
28467696 SYSIKPGTMIEWGNNWAR 95.24 7e-08
26822097 GYVEMTSIDADTSHDIVEAISGK 100.00 8e-04
26280517 EAESCDCIQGFQITHSIGGGTGSGMGTIIISK 100.00 8e-04
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